Determination of a cone-beam CT low-dose protocol for root fracture diagnosis in non-endodontically treated anterior maxillary teeth.

OBJECTIVES: The aim of this study was to determine a "low-dose protocol" which provides acceptable diagnostic accuracy for detection of root fractures in unrestored anterior maxillary teeth, using an ex vivo model. METHODS: 48 maxillary anterior teeth, half with horizontal or oblique root fractures, were imaged using CBCT in an anthropomorphic model. Nine X-ray exposure combinations were used, including the manufacturer's standard ("reference") exposure and high-resolution settings ("HiRes"), by varying kV, exposure time, and rotation angle. Measurements of Dose Area Product (DAP) were recorded. Five dental radiologists assessed the scans for root fractures and judged image quality. Parameters of diagnostic accuracy were calculated, including area under the Receiver Operating Characteristic curve (Az). Objective measures of image quality were made at the same exposure combinations using an image quality phantom. RESULTS: Although there was a significant linear relationship between DAP and mean Az, only the lowest DAP exposure combination had a mean Az significantly different to the reference exposure. There was no significant effect on other diagnostic accuracy parameters when using HiRes compared with the reference exposure. There was a significant positive relationship between DAP and contrast resolution. HiRes did not significantly improve contrast resolution and made a small improvement to spatial resolution. CONCLUSIONS: Scope existed for radiation dose reduction compared with the manufacturer's guidance. There was no improvement in diagnostic accuracy using HiRes settings. A cautious recommendation for this CBCT machine is that it is possible to achieve a dose reduction of about 20% compared with the reference exposure parameters.

Use of out-of-field contact shielding on patients in medical imaging: A review of current guidelines, recommendations and legislative documents.

The use of patient contact-shielding has become a topic of intensive scientific debate. While it has been common practice during the last decades, some studies have questioned the efficiency of using such shielding while others have highlighted the inconsistencies in its application. The objective of this work is to review current recommendations and legislative documents on the use of out-of-field shielding in X-ray imaging, including those from national authorities and from international and national organisations and professional bodies. The review, performed within the framework of the activities of EURADOS Working Group 12, covers available recommendations on use of contact shielding in adult, pregnant and paediatric patients in general radiography, fluoroscopy, computed tomography, mammography and dental radiology. It includes a comprehensive search of 83 documents from 32 countries and 6 international organisations over the last 39 years. In general, using shielding is recommended only under two conditions: if it does not compromise the diagnostic task and the performance of the procedure and/or if it reassures the patient and comforters that they are appropriately protected against potentially harmful effects of radiation. There are very few specific regulatory requirements to use shielding in a particular imaging modality, although they may consider use of shielding either as part of good radiological practice or as requirements for availability of protective or ancillary tools, without further specification of their use. There is a wide variety of positions among documents that recommend out-of-field shielding, those that do not recommend it and those that are not specific. Therefore, evidence-based consensus is still needed to ensure best and consistent practice.

Quality control in cone-beam computed tomography (CBCT) EFOMP-ESTRO-IAEA protocol (summary report).

The aim of the guideline presented in this article is to unify the test parameters for image quality evaluation and radiation output in all types of cone-beam computed tomography (CBCT) systems. The applications of CBCT spread over dental and interventional radiology, guided surgery and radiotherapy. The chosen tests provide the means to objectively evaluate the performance and monitor the constancy of the imaging chain. Experience from all involved associations has been collected to achieve a consensus that is rigorous and helpful for the practice. The guideline recommends to assess image quality in terms of uniformity, geometrical precision, voxel density values (or Hounsfield units where available), noise, low contrast resolution and spatial resolution measurements. These tests usually require the use of a phantom and evaluation software. Radiation output can be determined with a kerma-area product meter attached to the tube case. Alternatively, a solid state dosimeter attached to the flat panel and a simple geometric relationship can be used to calculate the dose to the isocentre. Summary tables including action levels and recommended frequencies for each test, as well as relevant references, are provided. If the radiation output or image quality deviates from expected values, or exceeds documented action levels for a given system, a more in depth system analysis (using conventional tests) and corrective maintenance work may be required.

Dose optimization for assessment of periodontal structures in cone beam CT examinations.

OBJECTIVES: To investigate the relationship between dose and image quality for a dedicated dental CBCT scanner using different scanning protocols and to set up an optimal imaging protocol for assessment of periodontal structures. METHODS: Radiation dose and image quality measurements were made using 3D Accuitomo 170 (J. Morita, Kyoto, Japan) dental CBCT scanner. The SedentexCT IQ phantom was used to investigate the relationship between contrast-to-noise ratio (CNR) and dose-area product. Subjective image quality assessment was achieved using a small adult skull phantom for the same range of exposure settings. Five independent observers assessed the images for three anatomical landmarks using a three-point visual grade analysis. RESULTS: When correlating the CNR of each scanning protocol to the exposure parameters used to obtain it, CNR decreased as these parameters decreased, especially current-exposure time product. When correlating to subjective image quality, the CNR level remained acceptable when 5 mA and 17.5 s or greater was selected and 80 kV could be used without compromising the CNR. CONCLUSIONS: For a dedicated CBCT unit, changing the rotation angle from 360° to 180° degrades image quality. By altering tube potential and current for the 360° rotation protocol, assessment of periodontal structures can be performed with a smaller dose without substantially affecting visualization.

Development of a low-dose protocol for cone beam CT examinations of the anterior maxilla in children.

OBJECTIVE: The aim of this study was to develop a low-dose protocol suitable for cone beam CT (CBCT) examination of an impacted maxillary canine in children by using a combination of dosimetry with subjective and objective image quality assessment. METHODS: Radiation dose and image quality measurements were made using a dental CBCT machine. An image quality phantom was used to investigate the relationship between objective image quality and dose-area product (DAP) for a broad range of exposure settings. Subjective image quality assessment was achieved using a paediatric skull phantom submerged in a water bath for the same range of exposure settings. Eight clinicians assessed each CBCT data set for nine aspects of image quality using a five-point rating scale of agreement. RESULTS: Acceptable image quality, defined using subjective judgements by the clinicians of the skull phantom images, was achievable with DAP values of 127 mGy cm(2) or greater and a polytetrafluoroethylene (PTFE) contrast-to-noise ratio (CNR) of 4.8 or greater. A cautious choice was made to recommend a low-dose protocol of 80 kV and 3 mA for implementation into clinical practice, corresponding to a DAP value of 146 mGy cm(2) and a PTFE CNR of 5.0. CONCLUSION: A low-dose protocol for this particular CBCT machine was established which represents as much as a 50% reduction compared with manufacturer's recommendations. ADVANCES IN KNOWLEDGE: To the authors' best knowledge, this is the first study that addresses dose optimization in paediatric clinical protocols in dental CBCT. Furthermore, this study explores the relationship between radiation dose, objective and subjective image quality.

Use of cone beam CT in children and young people in three United Kingdom dental hospitals.

BACKGROUND: There is limited evidence about the use of cone-beam computed tomography (CBCT) in paediatric dentistry. Appropriate use of CBCT is particularly important because of greater radiation risks in this age group. AIM: To survey the use of CBCT in children and young people in three Dental Hospitals in the United Kingdom (UK), with special attention paid to aspects of justification and optimisation. DESIGN: Retrospective analysis of patient records over a 24-month period, looking at CBCT examinations performed on subjects under 18 years of age. Clinical indications, region of interest, scan field of view (FoV), incidental findings and exposure factors used were recorded. RESULTS: There were 294 CBCT examinations performed in this age group, representing 13.7% of all scanned patients. CBCT was used more frequently in the >13 year age group. The most common use was for localisation of unerupted teeth in the anterior maxilla and the detection of root resorption. Optimisation of X-ray exposures did not appear to be consistent. CONCLUSIONS: When planning a CBCT service for children and young people, a limited FoV machine would be the appropriate choice for the majority of clinical requirements. It would facilitate clinical evaluation of scans, would limit the number of incidental findings and contribute to optimisation of radiation doses.

Effective dose range for dental cone beam computed tomography scanners.

OBJECTIVE: To estimate the absorbed organ dose and effective dose for a wide range of cone beam computed tomography scanners, using different exposure protocols and geometries. MATERIALS AND METHODS: Two Alderson Radiation Therapy anthropomorphic phantoms were loaded with LiF detectors (TLD-100 and TLD-100 H) which were evenly distributed throughout the head and neck, covering all radiosensitive organs. Measurements were performed on 14 CBCT devices: 3D Accuitomo 170, Galileos Comfort, i-CAT Next Generation, Iluma Elite, Kodak 9000 3D, Kodak 9500, NewTom VG, NewTom VGi, Pax-Uni3D, Picasso Trio, ProMax 3D, Scanora 3D, SkyView, Veraviewepocs 3D. Effective dose was calculated using the ICRP 103 (2007) tissue weighting factors. RESULTS: Effective dose ranged between 19 and 368 µSv. The largest contributions to the effective dose were from the remainder tissues (37%), salivary glands (24%), and thyroid gland (21%). For all organs, there was a wide range of measured values apparent, due to differences in exposure factors, diameter and height of the primary beam, and positioning of the beam relative to the radiosensitive organs. CONCLUSIONS: The effective dose for different CBCT devices showed a 20-fold range. The results show that a distinction is needed between small-, medium-, and large-field CBCT scanners and protocols, as they are applied to different indication groups, the dose received being strongly related to field size. Furthermore, the dose should always be considered relative to technical and diagnostic image quality, seeing that image quality requirements also differ for patient groups. The results from the current study indicate that the optimisation of dose should be performed by an appropriate selection of exposure parameters and field size, depending on the diagnostic requirements.

The classification of secondary colorectal liver cancer in human biopsy samples using angular dispersive x-ray diffraction and multivariate analysis.

The motivation behind this study is to assess whether angular dispersive x-ray diffraction (ADXRD) data, processed using multivariate analysis techniques, can be used for classifying secondary colorectal liver cancer tissue and normal surrounding liver tissue in human liver biopsy samples. The ADXRD profiles from a total of 60 samples of normal liver tissue and colorectal liver metastases were measured using a synchrotron radiation source. The data were analysed for 56 samples using nonlinear peak-fitting software. Four peaks were fitted to all of the ADXRD profiles, and the amplitude, area, amplitude and area ratios for three of the four peaks were calculated and used for the statistical and multivariate analysis. The statistical analysis showed that there are significant differences between all the peak-fitting parameters and ratios between the normal and the diseased tissue groups. The technique of soft independent modelling of class analogy (SIMCA) was used to classify normal liver tissue and colorectal liver metastases resulting in 67% of the normal tissue samples and 60% of the secondary colorectal liver tissue samples being classified correctly. This study has shown that the ADXRD data of normal and secondary colorectal liver cancer are statistically different and x-ray diffraction data analysed using multivariate analysis have the potential to be used as a method of tissue classification.