RESUMEN
Veterans living with HIV (VLWH) and hepatitis C virus (HCV) co-infection have an exacerbated risk of cardiovascular disease (CVD). It is unknown if HCV cure reduces CVD risk in this population. We evaluated changes in low-density lipoprotein (LDL), as a surrogate of CVD risk, 18âmonths after HCV cure in VLWH. We found significant increases in LDL in VLWH with advanced fibrosis, potentially increasing CVD risk. Lower LDL thresholds to initiate lipid-lowering therapies in VLWH after HCV cure may be warranted.
Asunto(s)
Infecciones por VIH , Hepatitis C Crónica , Veteranos , Humanos , Infecciones por VIH/tratamiento farmacológico , Infecciones por VIH/complicaciones , Masculino , Persona de Mediana Edad , Femenino , Hepatitis C Crónica/tratamiento farmacológico , Hepatitis C Crónica/complicaciones , Aterosclerosis , Lipoproteínas LDL/sangre , Enfermedades Cardiovasculares , Adulto , Antivirales/uso terapéutico , Coinfección , Medición de Riesgo , Hepatitis C/complicaciones , Hepatitis C/tratamiento farmacológicoRESUMEN
Background: Myiasis is a disease caused by the infestation of human tissue by the larval stage of various flies. It has been identified in sub-Saharan Africa and in tropical parts of the Americas. Cases have also been identified among travelers returning to the United States. Infestations may involve any part of the body, including the scalp, and open wounds may become infected with these larvae. The primary cause of wound myiasis in the western hemisphere is Cochliomyia hominivorax. Case Report: We present a case of wound myiasis in an adult Haitian male with a persistent wound for 2 years. To our knowledge, only 1 other report of wound myiasis in Haiti caused by C hominivorax has been published. Conclusion: Wound myiasis can occur in many tropical regions of the world, including Haiti. Because of the prevalence of global travel, clinicians should be familiar with the condition's diagnosis and management.
Asunto(s)
Prueba de VIH , Receptores de Antígenos de Linfocitos T/uso terapéutico , Serodiagnóstico del SIDA/métodos , Algoritmos , Infecciones por VIH/diagnóstico , Infecciones por VIH/tratamiento farmacológico , Humanos , Inmunoterapia Adoptiva/métodos , Masculino , Persona de Mediana Edad , Resultado del Tratamiento , Carga ViralRESUMEN
We present the genome sequence of Bacillus cereus LA2007, a strain isolated in 2007 from a fatal pneumonia case in Louisiana. Sequence-based genome analysis revealed that LA2007 carries a plasmid highly similar to Bacillus anthracis pXO1, including the genes responsible for the production and regulation of anthrax toxin.
