RESUMEN
BACKGROUND: Specific factors affect the outcome of full-thickness skin grafts after Mohs micrographic surgery. No recent clinical studies have systematically investigated the clinical factors that may affect the success of full-thickness skin grafts. OBJECTIVE: Our objective was to analyze patient data to define factors that may influence the success of full-thickness skin grafts. METHODS: We reviewed the clinical course of 117 patients who had full-thickness skin grafts after Mohs micrographic surgery. We analyzed these cases using patient variables, tumor variables, and skin graft variables and then correlated these variables to skin graft success. RESULTS: Delay of skin graft placement (> 1 day) was significantly correlated with subsequent skin graft success (p = 0.015). Skin graft necrosis was more likely to develop in men than in women (p = 0.021). CONCLUSION: A delay of 2 to 8 days between Mohs micrographic surgery and full-thickness skin graft placement resulted in a lower incidence of skin graft necrosis than no delay or a delay of 1 day.
Asunto(s)
Supervivencia de Injerto , Cirugía de Mohs , Trasplante de Piel , Adulto , Anciano , Anciano de 80 o más Años , Femenino , Humanos , Masculino , Persona de Mediana Edad , Complicaciones Posoperatorias , Neoplasias Cutáneas/cirugía , Factores de TiempoRESUMEN
This is the second reported case of minocycline-induced Sweet's syndrome (and the first such case to appear in the American literature). The syndrome developed in a 32-year-old man 10 days after minocycline therapy for acne was begun and resolved rapidly after discontinuation of the medication and start of oral prednisone therapy.