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2.
Can Fam Physician ; 53(10): 1722-30, 2007 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-17934036

RESUMEN

OBJECTIVE: To evaluate the effect of rooming-in (rather than standard nursery care) on the incidence and severity of neonatal abstinence syndrome among opioid-exposed newborns and on the proportion of mothers who retain custody of their babies at hospital discharge. DESIGN: Retrospective cohort study. SETTING: Lower mainland in southwestern British Columbia. PARTICIPANTS: We selected 32 women in the city of Vancouver known to have used heroin or methadone during pregnancy between October 2001 and December 2002. Comparison groups were a historical cohort of 38 women in Vancouver and a concurrent cohort of 36 women cared for in a neighbouring community hospital. MAIN OUTCOME MEASURES: Need for treatment with morphine, number of days of treatment with morphine, and whether babies were discharged in the custody of their mothers. RESULTS: Rooming-in was associated with a significant decrease in need for treatment of neonatal abstinence syndrome compared with the historical cohort (adjusted relative risk [RR] 0.40, 95% confidence interval [CI] 0.20 to 0.78) and the concurrent cohort (adjusted RR 0.39, 95% CI 0.20 to 0.75). Rooming-in was also associated with shorter newborn length of stay in hospital compared with both comparison groups. Newborns who roomed in at BC Women's Hospital were significantly more likely to be discharged in the custody of their mothers than babies in the historical cohort (RR 2.23, 95% CI 1.43 to 3.98) or the concurrent cohort (RR 1.52, 95% CI 1.15 to 2.53) were. CONCLUSION: Rooming-in might ease opioid-exposed newborns' transition to extrauterine life and promote more effective mothering.


Asunto(s)
Heroína/efectos adversos , Metadona/efectos adversos , Síndrome de Abstinencia Neonatal/epidemiología , Síndrome de Abstinencia Neonatal/etiología , Alojamiento Conjunto/estadística & datos numéricos , Adulto , Lactancia Materna/estadística & datos numéricos , Colombia Británica/epidemiología , Custodia del Niño/estadística & datos numéricos , Estudios de Cohortes , Comorbilidad , Femenino , Humanos , Recién Nacido , Tiempo de Internación/estadística & datos numéricos , Trastornos Relacionados con Opioides/epidemiología , Embarazo , Complicaciones del Embarazo/epidemiología , Efectos Tardíos de la Exposición Prenatal/epidemiología , Prevalencia , Fumar/epidemiología , Factores Socioeconómicos , Trastornos Relacionados con Sustancias/epidemiología
3.
Pediatrics ; 111(1): 15-20, 2003 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-12509548

RESUMEN

OBJECTIVE: The use of antibacterial agents to clean and dry the stump of the newborn's umbilical cord after birth has recently been abandoned by many neonatal units in favor of dry cord care. The objective of this study was to compare cord bacterial colonization and morbidity among newborns whose cords were treated with triple dye and alcohol versus dry cord care. METHODOLOGY: We randomly allocated 766 newborns to either 2 applications of triple dye to the umbilical cord stump on the day of birth with alcohol swabbing twice daily until the cord fell off (n = 384) or dry care (n = 382). Dry care consisted of spot cleaning soiled skin in the periumbilical area with soap and water, wiping it with a dry cotton swab or cloth, and allowing the area to air dry. Umbilical stumps on all subjects were swabbed and cultured. Community health nurses visiting at 2 or 3 days after hospital discharge observed the stump for signs of infection. Follow-up phone calls were made to mothers within 3 weeks of discharge. RESULTS: One infant in the dry care group was diagnosed with omphalitis. The umbilical stump was colonized with alpha-hemolytic streptococcus and coagulase-negative staphylococcus. Infants in the dry care group were significantly more likely to be colonized with Escherichia coli (34.2% vs 22.1%), coagulase-negative staphylococci (69.5% vs 50.5%), Staphylococcus aureus (31.3% vs 2.8%), and group B streptococci (11.7% vs 6.0%). Community health nurses were significantly more likely to observe exudate (7.4% vs 0.3%) and foul odor (2.9% vs 0.7%) among infants allocated to the dry care group during the home visit. CONCLUSIONS: Omphalitis remains a clinical issue. Cessation of bacteriocidal care of the umbilical stump must be accompanied by vigilant attention to the signs and symptoms of omphalitis.


Asunto(s)
Antiinfecciosos Locales/administración & dosificación , Infecciones Bacterianas/microbiología , Infecciones Bacterianas/prevención & control , Etanol/administración & dosificación , Violeta de Genciana/administración & dosificación , Proflavina/administración & dosificación , Compuestos de Amonio Cuaternario/administración & dosificación , Cordón Umbilical/microbiología , Combinación de Medicamentos , Escherichia coli/aislamiento & purificación , Humanos , Recién Nacido , Staphylococcus/clasificación , Staphylococcus/aislamiento & purificación
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