1.
Org Biomol Chem
; 12(23): 3924-31, 2014 Jun 21.
Artículo
en Inglés
| MEDLINE
| ID: mdl-24796538
RESUMEN
A method for the protecting group free synthesis of ß-urea-linked glycoconjugates has been developed. The one step process, involving reactions between urea and D-glucose, N-acetyl-D-glucosamine or D-xylose in acidic aqueous solution, furnishes the corresponding ß-urea glycosides in modest yields. This simple and efficient procedure is applicable to the synthesis of ß-urea tethered amino acid-carbohydrate conjugates.