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1.
Int J Mol Sci ; 24(11)2023 Jun 05.
Artículo en Inglés | MEDLINE | ID: mdl-37298711

RESUMEN

The effects of treadmill running under hypoxic conditions on joints and muscles of collagen-induced arthritis (CIA) rats were investigated. CIA rats were divided into normoxia no-exercise, hypoxia no-exercise (Hypo-no), and hypoxia exercise (Hypo-ex) groups. Changes were examined on days 2 and 44 of hypoxia with or without treadmill exercises. In the early stage of hypoxia, the expression of hypoxia-inducible factor (HIF)-1α increased in the Hypo-no and Hypo-ex groups. The expression of the egl-9 family hypoxia-inducible factor 1 (EGLN1) and vascular endothelial growth factor (VEGF) in the Hypo-ex group also increased. Under sustained hypoxia, the Hypo-no and Hypo-ex groups did not show increased expression of HIF-1α or VEGF, but p70S6K levels were elevated. Histologically, joint destruction was alleviated in the Hypo-no group, the loss of muscle weight in slow-twitch muscles was prevented, and muscle fibrosis was suppressed. In the Hypo-ex group, the preventive effect of a reduction in the slow-twitch muscle cross-sectional area was enhanced. Thus, chronic hypoxia in an animal model of rheumatoid arthritis controlled arthritis and joint destruction and prevented slow-twitch muscle atrophy and fibrosis. The combination of hypoxia with treadmill running further enhanced the preventive effects on slow-twitch muscle atrophy.


Asunto(s)
Artritis Experimental , Artritis Reumatoide , Ratas , Animales , Factor A de Crecimiento Endotelial Vascular/metabolismo , Artritis Reumatoide/metabolismo , Hipoxia/metabolismo , Atrofia Muscular , Subunidad alfa del Factor 1 Inducible por Hipoxia
2.
Mod Rheumatol Case Rep ; 7(2): 354-358, 2023 06 19.
Artículo en Inglés | MEDLINE | ID: mdl-36961737

RESUMEN

Patients with established rheumatoid arthritis (RA) are at risk of developing secondary sarcopenia. Both pharmacological and exercise interventions are essential for treatment. However, for such patients, exercise loads may lead to the progression of joint destruction and worsening of pain. The purpose of this report was to assess the feasibility of a home-based, low-intensity resistance exercise programme. The case was a 70-year-old female patient with sarcopenia secondary to RA. She was diagnosed with RA at 57 years of age and began medication, maintaining remission of disease activity. However, she did not exercise habitually and was relatively inactive in her daily life. Furthermore, she had kinesiophobia associated with her RA-related symptoms. We suggested implementing a home-based low-intensity resistance exercise programme >3 months, with the goal of exercising the lower extremities daily. The patient was asked to self-monitor using an exercise diary and attend monthly outpatient visits for repeat counselling and feedback. As a result, she was able to perform the exercise programme safely with high compliance, improving her kinesiophobia as well as physical inactivity, although her skeletal muscle mass did not change. Regular exercise and increased physical activity may help prevent the onset of sarcopenia. These results demonstrate the feasibility of implementing our exercise programme and support its potential for preventing the progression of sarcopenia. While questions remain in terms of treating sarcopenia, we believe that our findings will lead to the establishment of an exercise programme for patients with sarcopenia secondary to established rheumatoid arthritis.


Asunto(s)
Artritis Reumatoide , Entrenamiento de Fuerza , Sarcopenia , Femenino , Humanos , Anciano , Sarcopenia/diagnóstico , Sarcopenia/etiología , Sarcopenia/terapia , Terapia por Ejercicio/efectos adversos , Artritis Reumatoide/complicaciones , Artritis Reumatoide/terapia
3.
Prog Rehabil Med ; 7: 20220047, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-36160028

RESUMEN

Objectives: Patients with rheumatoid arthritis (RA)-related foot impairment have a high rate of sarcopenia. Treatment using a foot orthosis (FO) enables not only a reduction in pain while walking but also an increase in physical activity, helping to prevent further loss of muscle mass. However, the primary goal of treating RA is to maximize patients' long-term quality of life (QOL). We investigated whether FO treatment both increases physical activity and improves QOL. Methods: Among 31 patients with RA-related foot impairment, 15 with sarcopenia were treated with an FO for 6 months. Foot-specific QOL (measuring using the Self-Administered Foot Evaluation Questionnaire), foot pain, activities of daily living, and physical activity (walking-intensity activity and moderate- to vigorous-intensity activity) were compared before treatment and after 6 months of treatment. Results: Ten patients who completed 6 months of follow-up were analyzed. Significant QOL improvements were found in the Pain and Pain-Related category and the Physical Functioning and Daily Living category (P = 0.02-0.04); however, no significant changes were found in the Social Functioning, General Health and Well-Being, or Shoe-Related categories (P = 0.09-0.21). Foot pain and activities of daily living significantly improved (P = 0.01-0.04). Physical activity significantly increased for walking-intensity activity (P = 0.04) but did not change for moderate- to vigorous-intensity activity (P = 1.00). Conclusions: FO treatment in patients with RA-related foot impairment and sarcopenia increased light-intensity physical activity such as walking and improved physical QOL.

4.
J Hand Surg Am ; 47(1): 95.e1-95.e4, 2022 01.
Artículo en Inglés | MEDLINE | ID: mdl-34147318

RESUMEN

A patient presented with an abducted little finger due to the avulsion of the third volar interosseous muscle. For treatment, we transferred the fourth dorsal interosseous muscle arising from the ulnar side of the fourth metacarpal bone to the lateral band of the little finger.


Asunto(s)
Dedos , Huesos del Metacarpo , Dedos/cirugía , Humanos , Músculos , Transferencia Tendinosa , Arteria Cubital
5.
J Muscle Res Cell Motil ; 42(3-4): 429-441, 2021 12.
Artículo en Inglés | MEDLINE | ID: mdl-34687403

RESUMEN

To investigate the effects of treadmill running on two different types of skeletal muscle, we established a rat model of collagen-induced arthritis (CIA). The skeletal muscles studied were the extensor digitorum longus (EDL), which is rich in fast-twitch muscle fibers, and the soleus, which is rich in slow-twitch muscle fibers. The histological and transcriptional changes in these muscles at 14 and 44 days after immunosensitization were compared between rats that were forced to exercise (CIA ex group) and free-reared CIA rats (CIA no group). Change in protein expression was examined on day 14 after a single bout of treadmill running. Treadmill running had different effects on the relative muscle weight and total and fiber cross-sectional areas in each muscle type. In the soleus, it prevented muscle atrophy. Transcriptional analysis revealed increased eukaryotic translation initiation factor 4E (Eif4e) expression on day 14 and increased Atrogin-1 and peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α) expression on day 44 in the soleus in the CIA ex group, suggesting an interaction between muscle type and exercise. A single bout of treadmill running increased the level of Eif4e and p70S6K and decreased that of Atrogin-1 in the soleus on day 14. Treadmill running prevented muscle atrophy in the soleus in a rat model of rheumatoid arthritis via activation of mitochondrial function, as evidenced by increased PGC-1α expression.


Asunto(s)
Artritis Reumatoide , Carrera , Animales , Artritis Reumatoide/patología , Factor 4E Eucariótico de Iniciación , Fibras Musculares de Contracción Rápida , Fibras Musculares de Contracción Lenta , Músculo Esquelético , Atrofia Muscular/patología , Atrofia Muscular/prevención & control , Condicionamiento Físico Animal , Ratas
6.
J Hand Surg Asian Pac Vol ; 26(3): 472-476, 2021 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-34380390

RESUMEN

Volar dislocation of the distal radioulnar joint (DRUJ) is a rare injury. Furthermore, few reports exist regarding DRUJ dislocation with simultaneous elbow dislocation. Elbow dislocation is easily diagnosed and reduced, whereas a DRUJ dislocation is easily missed because of an inaccurate or missed examination of the wrist, which results in a chronic condition. We experienced a case of simultaneous elbow and volar DRUJ dislocation; the latter was found 2 months postinjury. To treat chronic volar dislocation of the DRUJ, surgical methods should include reconstruction of the triangle fibrocartilage complex because of scar tissue and severe instability. In this paper, we describe triangle fibrocartilage complex reconstruction by using the extensor carpi ulnaris half-slip. It is the first report of applying this technique for chronic volar DRUJ dislocation. This technique has a role in creating strong stabilization of the DRUJ and can be an effective treatment option.


Asunto(s)
Luxaciones Articulares , Codo , Antebrazo , Humanos , Luxaciones Articulares/diagnóstico por imagen , Luxaciones Articulares/cirugía , Fibrocartílago Triangular , Articulación de la Muñeca/diagnóstico por imagen , Articulación de la Muñeca/cirugía
7.
Arthritis Res Ther ; 23(1): 66, 2021 02 27.
Artículo en Inglés | MEDLINE | ID: mdl-33640011

RESUMEN

BACKGROUND: Although drug therapy for rheumatoid arthritis (RA) has recently improved, treating patients with established disease, whose hands have three major deformities (thumb deformity, finger deformities, and ulnar drift), remains a challenge. The underlying complex pathophysiology makes understanding these deformities difficult, and comprehensive assessment methods require accumulated skill with long learning curves. We aimed to establish a simpler composite method to understand the pathophysiology of and alterations in the hand deformities of patients with RA. METHODS: We established a rheumatoid hand cohort in 2004 and clinically evaluated 134 hands (67 patients). We repeated the evaluations in 2009 (100 hands of 52 patients) and 2015 (63 hands of 37 patients) after case exclusion. Thumb deformities, finger deformities (swan-neck and boutonnière deformity), and ulnar drift were semi-quantitated and entered as parameters into a two-step cross-sectional cluster analysis for the data in 2004. The parameters in each cluster were plotted at each evaluation point. Two-way analysis of covariance was used to examine whether differences existed between evaluation points and clusters of deformity parameters. RESULTS: Five clusters most appropriately described hand deformity: (i) cluster 1, minimal deformity; (ii) cluster 2, type 1 thumb deformity; (iii) cluster 3, thumb deformity and severe boutonnière deformity; (iv) cluster 4, type 2 or 3 thumb deformity and severe ulnar drift; and (v) cluster 5, thumb deformity and severe swan-neck deformity. Clusters 1 and 2 had higher function than cluster 5, and cluster 3 had moderate function. Clusters 1-4 had similar disease duration but showed different paths of deformity progression from disease onset. Clusters 1 and 2 represented conservative deformity parameters and clusters 3, 4, and 5 represented progressive deformity parameters. Over time, thumb deformity evolved into other types of deformities and swan-neck deformity worsened significantly. CONCLUSIONS: Our comprehensive analysis identified five deformity patterns and a progressive course in the rheumatoid hand. Knowledge of the characteristics of progressive deformity parameters may allow rheumatologists to more easily implement practical interventions and determine functional prognosis.


Asunto(s)
Artritis Reumatoide , Deformidades Adquiridas de la Mano , Artritis Reumatoide/epidemiología , Análisis por Conglomerados , Estudios Transversales , Mano , Deformidades Adquiridas de la Mano/epidemiología , Deformidades Adquiridas de la Mano/etiología , Humanos
8.
Mod Rheumatol ; 31(5): 997-1003, 2021 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-33153343

RESUMEN

OBJECTIVES: Foot impairment in rheumatoid arthritis (RA) may exacerbate sarcopenia from physical inactivity because of foot pain while walking. The present study aimed to investigate the prevalence of sarcopenia in patients with RA-associated foot impairment, and whether treatment with a foot orthosis improved physical activity and muscle quantity. METHODS: Thirty-two patients with RA were diagnosed as sarcopenic or nonsarcopenic, and the prevalence of sarcopenia was determined. Eleven patients with sarcopenia were treated with a foot orthosis. The following parameters were compared between baseline and after 6 months of treatment: physical activity (walking, moderate-intensity activity, and vigorous-intensity activity), foot pain while walking, Health Assessment Questionnaire (HAQ) score, and body composition parameters, including muscle quantity. RESULTS: Sarcopenia was present in 25/32 patients (78.1%). The use of a foot orthosis improved walking activity (p = .02), foot pain while walking (p = .02), and HAQ score (p = .02). However, there were no significant changes in moderate- or vigorous-intensity activities or body composition parameters, including muscle quantity. CONCLUSION: Patients with RA-associated foot impairment had a high rate of sarcopenia. Treatment with a foot orthosis increases light-intensity physical activity such as walking, but does not enhance moderate-to-vigorous-intensity activities or increase muscle quantity.


Asunto(s)
Artritis Reumatoide , Ortesis del Pié , Sarcopenia , Artritis Reumatoide/complicaciones , Artritis Reumatoide/terapia , Ejercicio Físico , Humanos , Músculo Esquelético , Sarcopenia/complicaciones , Sarcopenia/terapia
9.
J Hand Surg Glob Online ; 2(1): 55-60, 2020 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-35415477

RESUMEN

A major transition in the surgical treatment of rheumatoid arthritis has been facilitated by a recent paradigm shift in its diagnosis and treatment. Improved outcomes in the treatment of the rheumatoid thumb are desirable; however, the results of conventional surgery are less than ideal. Even if the rheumatoid arthritis is well-controlled, the progression of thumb deformity may persist owing to an ineffective deformity correction and an insufficient understanding of the mechanism by which the deformity occurs. The mechanism of rheumatoid thumb deformity should be considered, using it to base the appropriate correction. We applied a new deformity correction procedure that accounts for the mechanism of type I rheumatoid thumb deformity and obtained positive results without recurrence. Although the primary cause of type I thumb deformity is believed to be an extensor mechanism failure resulting from synovitis of the metacarpophalangeal (MCP) joint, surgical outcomes are negatively affected as a result of flexion contracture caused by the adductor pollicis (ADP). Because the ADP attaches to the ulnar sesamoid on the palmar side of MCP joint, we release the ADP tendon to improve flexion contracture of the MCP joint. We consider release of ADP to be effective in preventing the recurrence of flexion contracture of the MCP joint and re-tensioning of the extensor pollicis brevis. Rheumatoid thumb deformity can be restored by applying this procedure, improving a patient's outcome.

10.
J Hand Surg Eur Vol ; 45(2): 187-192, 2020 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-31722639

RESUMEN

The most common thumb deformity in rheumatoid arthritis is Nalebuff Type 1 deformity (boutonniere deformity). Type 1 deformity severely impairs hand function, and this impairment is evaluated by the Terrono classification. In some cases, the Terrono classification incorrectly categorizes advanced thumb deformity into earlier stages. We modified the Terrono classification by assessing the active range of motion of the interphalangeal joint prior to assessing the passive range of movement of the metacarpophalangeal joint. An active range of movement of the interphalangeal joint was strongly correlated with hand function. In 55 hands that we treated between 2004 and 2015, we compared the modified classification with the original Terrono classification. Our modified classification could detect advanced deformity earlier, and was more strongly correlated with hand function. Additionally, correlation analysis showed that advanced Type 1 deformity should be treated first, even in cases with severe ulnar drift. Our results suggest that the modified classification may benefit the treatment of Type 1 deformity, including joint-preserving surgery. Level of evidence: III.


Asunto(s)
Artritis Reumatoide , Deformidades Adquiridas de la Mano , Artritis Reumatoide/complicaciones , Estudios Transversales , Deformidades de la Mano , Deformidades Adquiridas de la Mano/etiología , Deformidades Adquiridas de la Mano/cirugía , Humanos , Articulación Metacarpofalángica/cirugía , Pulgar/anomalías , Pulgar/cirugía
11.
PM R ; 12(7): 692-698, 2020 07.
Artículo en Inglés | MEDLINE | ID: mdl-31702870

RESUMEN

BACKGROUND: Post-polio syndrome-induced muscle weakness may develop in limbs that have had normal muscle strength and have been considered unaffected by polio. OBJECTIVE: To investigate the utility of electromyography (EMG) for predicting future muscle weakness in clinically unaffected limb muscles of polio survivors. DESIGN: Retrospective study. SETTING: Academic polio clinic. PARTICIPANTS: Polio survivors (N = 77) who underwent EMG between April 2008 and March 2010 and were followed for at least 2 years. MATERIALS AND METHODS: Chart reviews were conducted to extract baseline EMG and manual muscle strength test (MMT) results to investigate the relationship between baseline EMG abnormalities and change in muscle strength over 2 years for various upper and lower limb muscles that control movement in the limb joints. MAIN OUTCOME MEASUREMENTS: Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of EMG findings for prediction of subsequent muscle weakness. RESULTS: EMG data were available for 44 deltoid, 59 biceps brachii, 60 triceps brachii, 59 vastus lateralis, 59 tibialis anterior, and 55 gastrocnemius (medial head) muscles. The percentage of muscles with an initial MMT of grade 5 that developed weakness over 2 years of follow-up was approximately 15% for most muscle types. Sensitivity of EMG to predict subsequent weakness was higher in the lower limbs (0.67-1.00). Specificity was higher in the biceps brachii (0.83). PPV was higher in the biceps brachii (0.50). NPV was higher in the lower limbs (0.89-1.00) but lower in the deltoid (0.75). CONCLUSION: EMG abnormalities were detected in some clinically normal muscles of polio survivors. EMG abnormalities predicted muscle weakness 2 years later, although the strength of this relationship varied depending on the muscle.


Asunto(s)
Electromiografía , Debilidad Muscular , Músculo Esquelético/fisiopatología , Poliomielitis , Humanos , Debilidad Muscular/diagnóstico , Debilidad Muscular/etiología , Poliomielitis/complicaciones , Poliomielitis/diagnóstico , Estudios Retrospectivos , Sobrevivientes
12.
Mod Rheumatol ; 30(6): 1009-1015, 2020 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-31625432

RESUMEN

Objectives: To assess the effectiveness and safety of interferon-free direct-acting antiviral (DAA) therapy for patients with concomitant hepatitis C virus (HCV) infection and rheumatic diseases (RDs), including rheumatoid arthritis (RA).Methods: This was a single-center observational case-series study conducted in Japan from 2014 to 2018. The primary endpoint was the sustained virological response (SVR) rate 24 weeks after the end of therapy (EoT24). We also evaluated hepatological and rheumatological outcomes and adverse events.Results: Of the 2314 patients with RDs, 18 received DAA therapy (RA = 11, other RDs = 7). The SVR rate for the initial DAA therapy was 89% (16/18). The remaining two achieved SVR with secondary DAA therapy. Along with HCV elimination, hepatological parameters improved significantly from baseline to EoT24. During the study period, no patients newly developed cirrhosis or HCC after HCV elimination. Several patients showed improvement in RDs activity. In RA patients, the simplified disease activity index decreased significantly from baseline to EoT24 (median [interquartile range]: 11.53 [5.14-14.89] vs. 4.06 [2.08-9.05], respectively). On-treatment adverse events were minimal, while two patients experienced tuberculosis reactivation after EoT.Conclusion: DAA therapy was effective and safe, providing hepatological and rheumatological benefits in HCV-infected patients with RDs. Immune reconstitution following HCV elimination should be noted.


Asunto(s)
Antivirales/uso terapéutico , Hepatitis C Crónica/tratamiento farmacológico , Enfermedades Reumáticas/complicaciones , Antivirales/administración & dosificación , Antivirales/efectos adversos , Femenino , Hepatitis C Crónica/complicaciones , Hepatitis C Crónica/virología , Humanos , Masculino , Persona de Mediana Edad , Respuesta Virológica Sostenida
13.
Int J Mol Sci ; 20(20)2019 Oct 15.
Artículo en Inglés | MEDLINE | ID: mdl-31618828

RESUMEN

Exercise therapy inhibits joint destruction by suppressing pro-inflammatory cytokines. The efficacy of pharmacotherapy for rheumatoid arthritis differs depending on the phase of the disease, but that of exercise therapy for each phase is unknown. We assessed the differences in the efficacy of treadmill running on rheumatoid arthritis at various phases, using rat rheumatoid arthritis models. Rats with collagen-induced arthritis were used as rheumatoid arthritis models, and the phase after immunization was divided as pre-arthritis and established phases. Histologically, the groups with forced treadmill running in the established phase had significantly inhibited joint destruction compared with the other groups. The group with forced treadmill running in only the established phase had significantly better bone morphometry and reduced expression of connexin 43 and tumor necrosis factor α in the synovial membranes compared with the no treadmill group. Furthermore, few cells were positive for cathepsin K immunostaining in the groups with forced treadmill running in the established phase. Our results suggest that the efficacy of exercise therapy may differ depending on rheumatoid arthritis disease activity. Active exercise during phases of decreased disease activity may effectively inhibit arthritis and joint destruction.


Asunto(s)
Artritis Reumatoide/etiología , Artritis Reumatoide/patología , Cartílago Articular/patología , Condicionamiento Físico Animal , Animales , Artritis Experimental , Artritis Reumatoide/diagnóstico por imagen , Artritis Reumatoide/metabolismo , Biomarcadores , Peso Corporal , Resorción Ósea/diagnóstico por imagen , Resorción Ósea/metabolismo , Cartílago Articular/diagnóstico por imagen , Cartílago Articular/metabolismo , Conexina 43/metabolismo , Citocinas/metabolismo , Modelos Animales de Enfermedad , Mediadores de Inflamación/metabolismo , Ratas , Membrana Sinovial/metabolismo , Membrana Sinovial/patología , Factor de Necrosis Tumoral alfa/metabolismo
14.
Am J Phys Med Rehabil ; 98(12): 1099-1105, 2019 12.
Artículo en Inglés | MEDLINE | ID: mdl-31246614

RESUMEN

OBJECTIVE: The aim of the study was to investigate the validity of using total score and to examine the constitution and characteristics of the Basic Movement Scale in postsurgery patients with hip fracture. DESIGN: The dimensionality and the threshold difficulty intervals between each score and item difficulty hierarchy of the Basic Movement Scale were examined using factor analysis and Rasch analysis in 37 patients admitted to our hospital between April and November 2015. RESULTS: For factor analysis, the contribution ratio of the first factor was 78.9%, that of the second factor was 6.5%, and there were no items that fit the Rasch analysis. The threshold was reversed at 6 of the 48 locations. The difficulty of the 12 Basic Movement Scale items was distributed roughly evenly among all 9 lots, with some deviation. There was one very easy item, and there were some items almost overlapping in difficulty. CONCLUSIONS: The results showed a unidimensional association between the items and evaluation index. The difficulty threshold of each score was approximated to the interval scale. Therefore, the Basic Movement Scale has evident construct validity and enables quantitative evaluation of physical ability, assessment of the effects of daily training, and general predictions of the feasibility of patients' clinical goals.


Asunto(s)
Evaluación de la Discapacidad , Fracturas de Cadera/rehabilitación , Locomoción , Equilibrio Postural , Estudios Transversales , Fijación de Fractura/rehabilitación , Humanos , Extremidad Inferior/fisiopatología , Psicometría , Recuperación de la Función/fisiología , Reproducibilidad de los Resultados
15.
Mod Rheumatol ; 29(1): 113-118, 2019 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-29448870

RESUMEN

OBJECTIVES: To establish a new assessment tool for ulnar drift (UD) in rheumatoid arthritis (RA). METHODS: We established an observational cohort of 67 patients (134 rheumatoid hands) beginning in 2004. Fifty-two patients (100 hands) had follow-up in 2009 and 37 patients (63 hands) completed follow-up in 2015. UD was evaluated with the Fearnley classification and our scoring method, which assesses four parameters of the metacarpophalangeal joint. Cluster analysis using UD parameters divided hands into groups. Changes in UD over time, correlation of the Fearnley stage and cluster with a functional assessment, and reliability of the parameters were analyzed. RESULTS: UD increased and worsened over time according to the trend test. A dendrogram indicated five clusters would be appropriate. Both the Fearnley classification and cluster were associated with function; however, our method related to function more linearly (R-squared: 0.42). We found one type of hand in which bone destruction precedes the joint dislocation and one type in which joint dislocation progresses with little deviation during UD progression. CONCLUSION: Our UD evaluation appeared to be simple and related to function. Additionally, it enables dividing UD hands into five stages. Thus, our assessment should be beneficial compared to the Fearnley classification in considering treatments of UD.


Asunto(s)
Artritis Reumatoide/complicaciones , Deformidades Adquiridas de la Mano , Luxaciones Articulares , Articulación Metacarpofalángica , Adulto , Anciano , Análisis por Conglomerados , Estudios de Cohortes , Progresión de la Enfermedad , Femenino , Deformidades Adquiridas de la Mano/diagnóstico , Deformidades Adquiridas de la Mano/etiología , Deformidades Adquiridas de la Mano/fisiopatología , Humanos , Japón , Luxaciones Articulares/diagnóstico , Luxaciones Articulares/etiología , Luxaciones Articulares/fisiopatología , Masculino , Articulación Metacarpofalángica/patología , Articulación Metacarpofalángica/fisiopatología , Persona de Mediana Edad , Gravedad del Paciente , Reproducibilidad de los Resultados , Índice de Severidad de la Enfermedad , Resultado del Tratamiento
16.
J Phys Ther Sci ; 30(10): 1262-1266, 2018 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-30349161

RESUMEN

[Purpose] The balance exercise assist robot is a training device based on a personal transport assistance robot ridden in the standing position. The personal transport assistance robot uses an inverted pendulum control system and moves in response to movements of the user's center of gravity. The purpose of this study was to describe the characteristics of postural control during the action of stopping the personal transport assistance robot. [Participants and Methods] Eleven healthy male participants were required to maintain a standing position for 30 s; each task was performed 10 times. The measurement conditions were as follows: (1) on the floor; (2) on the robot, touching the handlebars; and (3) on the robot, not touching the handlebars. [Results] During the robotic tasks, the total locus lengths of the center of gravity and total joint momentums of the hip, knee, and ankle joints were larger, and the amount of displacement of the center of pressure was smaller than that during the floor task. Posture control on the robot was performed actively by mechanical interaction of the ankle, knee, and hip joints within a small base of support. [Conclusion] The balance exercise assist robot can be useful for postural control exercises because maintaining a standing position on the personal transport assistance robot required active postural control.

17.
Gait Posture ; 66: 228-235, 2018 10.
Artículo en Inglés | MEDLINE | ID: mdl-30212782

RESUMEN

BACKGROUND: The biomechanical abnormalities in patients with posterior tibial tendon dysfunction (PTTD) have been described, but few studies have investigated biomechanical chains of adjacent joints. Therefore, we examined the gait pattern of the lower extremity in subjects with PTTD, focusing on the hip and knee joints. METHODS: We compared 19 PTTD patients (average age: 67.1) with 30 age-matched control subjects (average age: 65.1). Gait analysis was performed with a nine-camera motion-capture system and four force plates, using the Vicon Plug-In-Gait and Vicon Nexus software. Temporal-spatial parameters were compared between PTTD and control subjects, and motion and ground reaction force data were compared between the affected limb, the contralateral limb, and the right limb in control subjects. RESULTS: Subjects with PTTD had increased stance phase ratio and decreased stride length, cadence, and gait speed. The limbs of subjects with PTTD showed increased knee internal rotation at lording response, which was biased to abduction in the knee joint during the gait cycle, and irregular hip flexion and knee extension moment in the terminal stance, even under control of gait speed. SIGNIFICANCE: We believe that the subjects with PTTD have an increased risk of knee osteoarthritis in both the affected and contralateral limbs.


Asunto(s)
Análisis de la Marcha/métodos , Articulación de la Cadera/fisiopatología , Articulación de la Rodilla/fisiopatología , Extremidad Inferior/fisiopatología , Disfunción del Tendón Tibial Posterior/fisiopatología , Anciano , Fenómenos Biomecánicos , Femenino , Pie/fisiopatología , Marcha/fisiología , Humanos , Cinética , Masculino , Persona de Mediana Edad , Rango del Movimiento Articular/fisiología , Análisis Espacio-Temporal
18.
Int J Surg Case Rep ; 48: 87-91, 2018.
Artículo en Inglés | MEDLINE | ID: mdl-29913431

RESUMEN

INTRODUCTION: Closed flexor tendon rupture after a malunited distal radius fracture is rare and usually becomes apparent early after the fracture. Most cases are accompanied by a severe distal radio-ulnar joint capsule injury, wherein bone protrusion (as a spur) directly stresses the tendons. We experienced a nonspecific flexor tendon rupture associated with an old fracture and the presence of collagen disease. PRESENTATION OF CASE: A 63-year-old woman presented with delayed complete rupture of the flexor digitorum profundus (FDP) of the fifth digit. Her history included closed fracture on the left wrist at age 13 years. At 27 years, she was diagnosed with Behçet syndrome and commenced oral prednisolone 10 mg/day. At the current admission, physical examination revealed that she was incapable of fifth finger flexion after minor passive extension. The fifth digit FDP rupture appeared to be due to damage at the wrist-level fracture site. A tiny capsule rupture was seen on the volar side of the distal radio-ulnar joint. We resected ulnar head osteophytes protruding from the capsule hole and transferred tendon from the fifth FDP to the fourth FDP. CONCLUSION: Reportedly, metalloproteases weaken tendon structure by acting as a collagenase in patients with Behçet syndrome. Also, vasculitis next to a tendon and steroid intake are considered to impede the tendon repair process. Hence, even minor trauma may lead to complete tendon rupture. Although an injury seems slight, we should take into account the possible history of bone and joint trauma.

19.
Am J Phys Med Rehabil ; 97(5): 316-322, 2018 05.
Artículo en Inglés | MEDLINE | ID: mdl-28930758

RESUMEN

OBJECTIVE: The aim of this study was to examine the correlation between basic movement ability and activities of daily living (ADL) in elderly patients after hip fracture surgery and predict ADL outcomes from changes in basic movement ability. DESIGN: Fifty-four patients receiving rehabilitation after hip fracture surgery were collected prospectively. Ambulatory ability was evaluated using a Basic Movement Scale (BMS), and ADL was evaluated using the motor subscale of the Functional Independence Measure (motor-FIM). From the results of evaluating BMS and motor-FIM weekly, the important postoperative period to regain ADL was investigated. RESULTS: There was a close correlation between BMS and motor-FIM scores at each evaluation point (r = 0.971, P < 0.001) and a significant correlation between weekly BMS and motor-FIM gains (r = 0.741, P < 0.001). Cluster analysis of BMS scores from postoperative week (POW) 2 to 12 showed three patterns of change, with BMS scores at POW 2 reflecting the outcome. CONCLUSIONS: The very strong correlation between BMS and motor-FIM scores suggests that BMS is a favorable indicator of changes in ADL. Because basic movement ability at POW 2 also reflected the prognosis, constructive interventions should be implemented early to help patients ambulate and regain other basic movements by no later than POW 2.


Asunto(s)
Actividades Cotidianas , Fijación de Fractura/rehabilitación , Fracturas de Cadera/rehabilitación , Recuperación de la Función/fisiología , Anciano , Anciano de 80 o más Años , Análisis por Conglomerados , Evaluación de la Discapacidad , Femenino , Fracturas de Cadera/fisiopatología , Fracturas de Cadera/cirugía , Humanos , Masculino , Persona de Mediana Edad , Movimiento , Periodo Posoperatorio , Factores de Tiempo , Resultado del Tratamiento
20.
Mod Rheumatol ; 27(2): 266-270, 2017 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-27539207

RESUMEN

OBJECTIVE: To examine the recurrence of deformity after silicone implant arthroplasty combined with resection arthroplasty for severe forefoot deformity in patients with rheumatoid arthritis. METHODS: We reviewed the long-term results of this procedure for 27 feet in 15 patients. Their average age and disease duration at the time of operation were 58.6 years and 17.5 years, respectively, and the average follow-up period was 10.3 years. RESULTS: An improved hallux valgus angle (45.3° preoperatively, 23.6° 6 months after operation) was maintained. By contrast, deformity and dislocation of lesser toe had recurred at the final follow-up; the angle between the proximal phalanx and the metatarsal of the second toe improved 13.4° with recurrence of 22.5°, the angle between the proximal phalanx and ground surface improved 22.4° with recurrence of 34.5. Furthermore, claw toe deformity at the final follow-up was significantly worse in the group whose hallux valgus deformity was observed 6 months after operation. CONCLUSION: This procedure could maintain the alignment of the first metatarsophalangeal joint, but the recurrence of claw toe deformity is a problem and the relation between the first toe and the lesser toe is an important consideration.


Asunto(s)
Artritis Reumatoide/cirugía , Artroplastia/métodos , Hallux Valgus/cirugía , Articulación Metatarsofalángica/cirugía , Anciano , Anciano de 80 o más Años , Artritis Reumatoide/diagnóstico por imagen , Femenino , Estudios de Seguimiento , Hallux Valgus/diagnóstico por imagen , Humanos , Luxaciones Articulares/diagnóstico por imagen , Luxaciones Articulares/cirugía , Masculino , Huesos Metatarsianos/diagnóstico por imagen , Huesos Metatarsianos/cirugía , Articulación Metatarsofalángica/diagnóstico por imagen , Persona de Mediana Edad , Prótesis e Implantes , Radiografía , Recurrencia , Siliconas , Resultado del Tratamiento
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