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Angew Chem Int Ed Engl ; 58(43): 15299-15303, 2019 10 21.
Artículo en Inglés | MEDLINE | ID: mdl-31411794

RESUMEN

Bio-inspired functional microcapsules have attracted increasing attention in many fields from physical/chemical science to artificial-cell engineering. Although particle-stabilised microcapsules are advantageous for their stability and functionalisation potential, versatile methods for their functionalisation are desired to expand their possibilities. This study reports a water-in-oil microdroplet stabilised with amphiphilic DNA origami nanoplates. By utilising DNA nanotechnology, DNA nanoplates were designed as a nanopore device for ion transportation and to stabilise the oil-water interface. Microscopic examination revealed the microcapsule formed by the accumulation of amphiphilic DNA nanoplates at the oil-water interface. Ion current measurements revealed the nanoplate pores functioned as channel to transport ions. These findings provide a general strategy for the programmable design of microcapsules to engineer artificial cells and molecular robots.


Asunto(s)
ADN/química , Nanoporos , Nanoestructuras/química , Colesterol/química , Fluoresceínas/química , Microscopía de Fuerza Atómica , Microscopía Confocal , Aceites/química , Polietilenglicoles/química , Agua/química
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