Cognitive effects of one season of head impacts in a cohort of collegiate contact sport athletes.

OBJECTIVE: To determine whether exposure to repetitive head impacts over a single season negatively affects cognitive performance in collegiate contact sport athletes. METHODS: This is a prospective cohort study at 3 Division I National Collegiate Athletic Association athletic programs. Participants were 214 Division I college varsity football and ice hockey players who wore instrumented helmets that recorded the acceleration-time history of the head following impact, and 45 noncontact sport athletes. All athletes were assessed prior to and shortly after the season with a cognitive screening battery (ImPACT) and a subgroup of athletes also were assessed with 7 measures from a neuropsychological test battery. RESULTS: Few cognitive differences were found between the athlete groups at the preseason or postseason assessments. However, a higher percentage of the contact sport athletes performed more poorly than predicted postseason on a measure of new learning (California Verbal Learning Test) compared to the noncontact athletes (24% vs 3.6%; p < 0.006). On 2 postseason cognitive measures (ImPACT Reaction Time and Trails 4/B), poorer performance was significantly associated with higher scores on several head impact exposure metrics. CONCLUSION: Repetitive head impacts over the course of a single season may negatively impact learning in some collegiate athletes. Further work is needed to assess whether such effects are short term or persistent.

Zinc gluconate and the common cold: a controlled clinical study.

A report in 1984 on the success of zinc gluconate against common cold symptoms could not be confirmed in three subsequent studies, which are now known to have used formulations that inactivated zinc. A non-chelating formulation including glycine, which releases 93% of contained zinc into saliva, was tested in a randomized, placebo-controlled, double-blind trial in 73 young adults. Efficacy was recorded in symptom diaries using a symptom severity rating. Patients' symptoms first appeared 1.34 days prior to entry to the study in both groups. Disappearance of symptoms occurred after an additional 4.9 days for zinc-treated patients versus 6.1 days for placebo-treated patients. A difference was noted in the efficacy of treatment if it was started 1 day after symptom onset: cold duration was an additional 4.3 days in zinc-treated patients compared with 9.2 days for placebo-treated patients. Cough, nasal drainage and congestion were the symptoms most affected, and only mild side-effects were noted.

Medical withdrawals from college for mental health reasons and their relation to academic performance.

A collaborative study among the university health service, the dean's office, and the registrar's office examined the academic performance of 77 students who took medical withdrawals for mental health reasons from Dartmouth College during a 3-year period. In 71.4% of the cases, students withdrew from a term in progress; the remainder arranged to withdraw after they had completed a term but before starting a new term. Depression was a major factor in approximately half of the withdrawals. Grade point average improved significantly after return from the withdrawal, with a large jump in individual term averages occurring between the terms immediately preceding and immediately following return. We found no significant difference between the number of students who experienced disciplinary trouble before withdrawal and those who were disciplined afterward. Students who were depressed at the time of withdrawal did not fare as well academically upon return as those students who had not been depressed. The data suggest that procedures for handling mental health withdrawals and readmission are important ways in which the campus counseling center can support the university's academic mission.

Acute short-term memory loss from trimethyltin exposure.

We report a case of organic tin exposure in a graduate chemistry student. The inhalational and transcutaneous exposure occurred following a laboratory explosion. The patient initially presented with first and second degree burns of the face and chest, and developed an acute loss of short-term memory 72 hours after exposure. The memory loss gradually improved over the course of several months.

Alcohol consumption by college undergraduates: current use and 10-year trends.

In a carefully executed study with a high response rate, a random sample of 10% of the undergraduate student body at a rural New England university was surveyed as to the subjects' use of alcohol in 1987. Over 87% of the surveyed students returned questionnaires. The results were compared to similar studies conducted on the campus in 1977 and 1983. "Daily or almost daily" use of alcohol was registered by 4.7% of the respondents, which represents a continuing decrease in daily consumption from earlier studies. One-fourth of the sample indicated drinking only one drink or fewer per week, contrary to the common perception on the campus. Nevertheless, 25.5% recorded a hangover, 7.5% recorded vomiting from drinking too much and 4.4% recorded a blackout, all "in the last week." Compared to the U.S. population, alcohol consumption appears to be more evenly distributed in the college sample but, still, most of the drinking is done by one-fifth of both groups.

Drug use among college undergraduates: current use and 10-year trends.

A random sample of 10% of the undergraduate student body at a rural New England university were surveyed as to their use of drugs in 1987. Over 87% of the surveyed students returned questionnaires. Results indicated that alcohol is clearly the "drug of choice" on the campus, and the second most used drug is marijuana. The 1987 survey findings were also compared to similar studies conducted on the campus in 1977 and 1983. Over the decade there has been a decrease in daily, weekly, and monthly use of marijuana. Cocaine use was greatest in the 1983 survey, but the 1987 figures were still somewhat higher than those of 1977. Hallucinogen use has remained low across all three observation points. Students indicating they had substance-dependent parents showed more use of cocaine, "ecstasy," and sedative-hypnotic drugs than their fellow students.

Visits to the college health service for alcohol-related injuries.

A study of alcohol-related injuries presenting to the local emergency room and the campus health service indicated an annualized rate of 25.16 injuries per thousand students. Twenty-four percent of injuries presenting to the emergency room were assessed as alcohol-related; another 6% were listed as being "suspected." Less than 4% of the injuries presenting to the campus health service were assessed as alcohol-related, and a similar number were listed as "suspected." Males had a significantly higher rate of alcohol-related injuries than females, and undergraduates had a higher rate than graduate students. Differences among the undergraduate classes were not significant. An investigation of the time of presentation indicated that most alcohol-related injuries occurred after hours and on weekends.