RESUMEN
Aim: To evaluate the CANLPH score in in-hospital mortality after coronary artery bypass grafting. Materials & methods: The 999 patients were included in this retrospective cohort study. Neutrophil/lymphocyte ratio, C-reactive protein/albumin ratio and platelet/hemoglobin ratio were determined and the CANLPH score was calculated as the sum score of 0 or 1 by the cutoff in each ratio. Results: Twenty-five patients who reached the primary end point were defined as the mortality group and the remaining as the nonmortality group. The CANLPH score was noninferior to the European System for Cardiac Operative Risk Evaluation II in receiver-operating characteristic curve analysis with difference between AUC: 0.0162, standard error (SE): 0.0394, z statistics: 0.682 and p = 0.494. Conclusion: The CANLPH score may be more appropriate in assessing the risk of in-hospital mortality after coronary artery bypass grafting.
Lay abstract Mortality, morbidity and complications of coronary artery disease depend largely on inflammatory processes. The CANLPH score, a combination of three different ratios, can better determine inflammation. We aimed to evaluate the CANLPH score in in-hospital mortality after coronary artery bypass grafting. The 999 patients were classified into two groups according to the primary end point. Twenty-five patients (2.5%) who reached the primary end point were defined as the mortality group and the remaining 974 patients as the nonmortality group. The multivariate logistic regression analysis showed that the European System for Cardiac Operative Risk Evaluation II, neutrophil/lymphocyte ratio, platelet/hemoglobin ratio and the CANLPH score were independent predictors of primary end point after coronary artery bypass grafting. The CANLPH score may be more appropriate than neutrophil/lymphocyte ratio, C-reactive protein/albumin ratio and platelet/hemoglobin ratio in assessing the risk of in-hospital mortality after coronary artery bypass grafting.