RESUMEN
Intimate partner violence (IPV) is associated with a high risk of HIV acquisition. Pre-exposure prophylaxis (PrEP), which does not require partner knowledge or consent, is a promising HIV risk reduction option for women experiencing IPV. Drawing on semi-structured interviews with 26 women experiencing IPV within the last six months, this study explored the feasibility and acceptability of PrEP use in this population. Slightly more than half of the women in this study expressed interest in taking PrEP when in a relationship with an abusive partner. Potential barriers to PrEP, discussed regardless of women's expressed interest in PrEP, included fear of side effects and long-term health concerns, low risk perceptions, potential partner interference, and prioritizing coping with the relationship over HIV prevention. When offering PrEP counseling, providers should inquire about IPV, as women in violent relationships may require tailored counseling to address barriers and concerns specific to their situation.
Asunto(s)
Infecciones por VIH/prevención & control , Conocimientos, Actitudes y Práctica en Salud , Violencia de Pareja/psicología , Aceptación de la Atención de Salud , Profilaxis Pre-Exposición , Maltrato Conyugal/psicología , Adolescente , Adulto , Anciano , Consejo , Estudios de Factibilidad , Femenino , Infecciones por VIH/epidemiología , Humanos , Masculino , Persona de Mediana Edad , Conducta de Reducción del Riesgo , Parejas SexualesRESUMEN
HIV and childhood sexual abuse (CSA) are intersecting public health problems for women. We pilot tested an integrated sexual risk reduction intervention for women with a history of CSA that addressed both the consequences of CSA [based on the Traumagenic Dynamics (TD) framework] and the antecedents of sexual risk behavior (based on the Information-Motivation-Behavioral Skills [IMB] model). Women with a history of CSA who were attending a public STI clinic (n = 84) were randomly assigned to a five-session integrated TD/IMB (experimental) group intervention or to a time-matched IMB-guided sexual risk reduction (control) group intervention. Preliminary findings indicated that women in the integrated TD/IMB intervention reduced their average number of episodes of unprotected sex with a primary partner, their alcohol use, and their likelihood of being in a violent relationship, relative to women in the IMB-only group. Our findings suggest that sexual risk reduction interventions that address both the consequences of CSA and the antecedents of sexual risk behavior may be efficacious in reducing sexual risk behavior among women who were sexually abused.
Asunto(s)
Adultos Sobrevivientes del Maltrato a los Niños/psicología , Terapia Conductista/métodos , Motivación , Conducta de Reducción del Riesgo , Asunción de Riesgos , Conducta Sexual/psicología , Sexo Inseguro/estadística & datos numéricos , Adulto , Consumo de Bebidas Alcohólicas/prevención & control , Niño , Femenino , Humanos , Parejas Sexuales , Resultado del Tratamiento , Sexo Inseguro/psicologíaRESUMEN
BACKGROUND: Black men who have sex with men (MSM) are disproportionately infected with HIV and are less well retained along the HIV continuum of care. We report on the feasibility of a peer support text messaging intervention designed to increase retention in HIV care and HIV medication adherence among HIV-infected black men who have sex with men. METHODS: Based on formative research, a cell phone app was developed to support a peer-based text messaging intervention. The app allowed the researchers to view text messages sent between mentors and mentees, but did not allow them to view other text messages sent by these phones. Three HIV-infected black men who have sex with men were recruited to serve as volunteer peer mentors. They were trained in motivational techniques, peer support skills, and skills for improving appointment attendance and medication adherence. Mentees (N = 8) received the intervention for 1 month. Mentees completed a postintervention survey and interview. RESULTS: The peer mentor text messaging intervention was feasible. Mentors delivered support in a nonjudgmental, motivational way. However, technical and other implementation problems arose. Some mentees desired more frequent contact with mentors, and mentors reported that other commitments made it difficult at times to be fully engaged. Both mentors and mentees desired more personalized contact (ie, phone calls). CONCLUSIONS: A text messaging peer mentor intervention was feasible. Additional research with a larger sample is needed to determine optimal ways to improve mentors' engagement in the intervention and to determine intervention acceptability and efficacy. In future studies, peer support phone calls could be incorporated.
Asunto(s)
Continuidad de la Atención al Paciente , Infecciones por VIH/diagnóstico , Infecciones por VIH/terapia , Homosexualidad Masculina , Cumplimiento de la Medicación , Sistemas Recordatorios/estadística & datos numéricos , Envío de Mensajes de Texto/estadística & datos numéricos , Adulto , Negro o Afroamericano , Consejo , Infecciones por VIH/prevención & control , Humanos , Masculino , Persona de Mediana Edad , Proyectos Piloto , Estados UnidosRESUMEN
HIV positive Black men who have sex with men (MSM) are retained in HIV medical care at suboptimal rates. Interventions targeted to Black MSM are needed to help to improve their retention in care. The purposes of this study were to investigate the use of mobile technology among HIV+ Black MSM and to explore participants' thoughts about the use of mobile technology for HIV retention in care interventions. Twenty-two HIV+ Black MSM completed a technology use survey and participated in a qualitative interview regarding technology-based interventions. The majority of participants (95%) had access to a cell phone, and used their phones frequently (median 3 hours/day). Men preferred interventions that would allow for anonymous participation and that would provide individually tailored support. Mobile technology is a promising approach to intervention delivery for both younger and older HIV+ Black MSM. These interventions should incorporate features that are desirable to men (i.e., anonymous participation and individual tailoring).
Asunto(s)
Negro o Afroamericano , Teléfono Celular , Infecciones por VIH/tratamiento farmacológico , Homosexualidad Masculina , Adulto , Población Negra , Humanos , Entrevistas como Asunto , Masculino , Persona de Mediana Edad , Prioridad del Paciente , Encuestas y CuestionariosRESUMEN
We report results from a randomized controlled trial designed to evaluate the efficacy of a video-based sexual risk reduction intervention and to measure assessment reactivity. Patients (N = 1010; 56 % male; 69 % African American) receiving care at a sexually transmitted infection (STI) clinic were assigned to one of four conditions formed by crossing assessment condition (i.e., sexual health vs. general health) with intervention condition (i.e., sexual risk reduction intervention vs. general health promotion). After completing their assigned baseline assessment, participants received their assigned intervention, and subsequently returned for follow-up assessments at 3, 6, 9, and 12 months. Participants in all conditions reduced their self-reported sexual risk behavior, and the incidence of new STIs declined from baseline through the follow-ups; however, there was no effect of intervention or assessment condition. We conclude that further risk reduction will require more intensive interventions, especially in STI clinics that already provide excellent clinical care.
Asunto(s)
Infecciones por VIH/prevención & control , Promoción de la Salud/métodos , Conducta de Reducción del Riesgo , Conducta Sexual , Enfermedades de Transmisión Sexual/prevención & control , Grabación en Video , Adolescente , Adulto , Instituciones de Atención Ambulatoria , Terapia Conductista/métodos , Consejo , Femenino , Estudios de Seguimiento , Humanos , Incidencia , Masculino , Persona de Mediana Edad , Evaluación de Procesos y Resultados en Atención de Salud , Parejas Sexuales , Encuestas y Cuestionarios , Estados Unidos/epidemiologíaRESUMEN
Randomized controlled trials (RCTs) remain the gold standard for evaluating intervention efficacy but are often costly. To optimize their scientific yield, RCTs can be designed to investigate multiple research questions. This paper describes an RCT that used a modified Solomon four-group design to simultaneously evaluate two, theoretically-guided, health promotion interventions as well as assessment reactivity. Recruited participants (N = 1010; 56% male; 69% African American) were randomly assigned to one of four conditions formed by crossing two intervention conditions (i.e., general health promotion vs. sexual risk reduction intervention) with two assessment conditions (i.e., general health vs. sexual health survey). After completing their assigned baseline assessment, participants received the assigned intervention, and returned for follow-ups at 3, 6, 9, and 12 months. In this report, we summarize baseline data, which show high levels of sexual risk behavior; alcohol, marijuana, and tobacco use; and fast food consumption. Sexual risk behaviors and substance use were correlated. Participants reported high satisfaction with both interventions but ratings for the sexual risk reduction intervention were higher. Planned follow-up sessions, and subsequent analyses, will assess changes in health behaviors including sexual risk behaviors. This study design demonstrates one way to optimize the scientific yield of an RCT.
Asunto(s)
Conductas Relacionadas con la Salud , Promoción de la Salud/métodos , Proyectos de Investigación , Conducta de Reducción del Riesgo , Conducta Sexual , Adolescente , Adulto , Condones/estadística & datos numéricos , Recolección de Datos , Comida Rápida , Femenino , Humanos , Masculino , Satisfacción del Paciente , Grupos Raciales , Enfermedades de Transmisión Sexual/epidemiología , Factores Socioeconómicos , Trastornos Relacionados con Sustancias/epidemiología , Grabación de Cinta de Video , Adulto JovenRESUMEN
OBJECTIVE: The purpose of this study is to investigate alcohol use, sexual risk behaviour and trichomoniasis in a sample of low-income, largely minority, women patients at a publicly funded sexually transmitted disease (STD) clinic in the USA. METHODS: Baseline data, collected as part of a clinical trial, were used. Patients (688 women, 46% of the overall sample) completed an audio computer-assisted self-interview that included questions about their alcohol use and sexual behaviours. Trichomoniasis was determined from vaginal swab specimens obtained during a standard clinical exam. RESULTS: Women (n=580; 18-56 years of age; 64% African-American) who reported that they had consumed alcohol at least once in the past year were included in the analyses. Of the 580 women, 157 were diagnosed with an STD and 80 tested positive for trichomoniasis. Trichomoniasis was associated with having multiple sexual partners (OR=1.09; 95% CI 1.01 to 1.17) but not with the number or proportion of unprotected sex events (p>0.05) in the past 3 months. Quantity of alcohol use (drinks per drinking day, drinks per week, and peak consumption) moderated the association between the number of sexual partners and trichomoniasis. CONCLUSIONS: The number of sexual partners predicted the probability of trichomoniasis when women reported drinking large quantities of alcohol. Because having multiple sexual partners increases the risk for STD transmission, interventions designed for at-risk women should address the quantity of alcohol consumed as well as partner reduction to reduce the risk for trichomoniasis.
Asunto(s)
Consumo de Bebidas Alcohólicas/efectos adversos , Asunción de Riesgos , Conducta Sexual , Enfermedades de Transmisión Sexual/epidemiología , Tricomoniasis/epidemiología , Trichomonas vaginalis/aislamiento & purificación , Adolescente , Adulto , Femenino , Humanos , Entrevistas como Asunto , Persona de Mediana Edad , Parejas Sexuales , Enfermedades de Transmisión Sexual/parasitología , Tricomoniasis/parasitología , Estados Unidos/epidemiología , Vagina/parasitología , Adulto JovenRESUMEN
We assessed determinants of condom use postulated by the IMB model among STD patients (N = 1474). The model provided acceptable fit to the data (CFI = 0.99, RMSEA = .04). Information was unrelated to condom use but had a negative effect on behavioral skills. Motivation had a positive effect on behavioral skills and condom use. Behavioral skills had a positive effect on condom use. In multiple-groups analyses, stronger associations between motivation and condom use were found among participants reporting no prior STD treatment. Interventions among STD patients should include activities addressing condom use motivation and directly enhancing condom skills.
Asunto(s)
Conducta , Condones/estadística & datos numéricos , Motivación , Pacientes/psicología , Enfermedades de Transmisión Sexual/prevención & control , Adulto , Análisis Factorial , Femenino , Humanos , Masculino , Modelos Teóricos , Valor Predictivo de las Pruebas , Encuestas y CuestionariosRESUMEN
Sexual partner concurrency plays an important role in HIV and STD transmission. The shortage of African-American men may facilitate partner concurrency. This study evaluated whether the male-to-female ratio was associated with African-American participants' number of recent sexual partners, and whether this association differed by gender. Multilevel modeling was used to determine the influence of individual (i.e., gender) and population-level (i.e., sex ratio) variables on the number of recent sexual partners. African-American patients (N = 915; 52% male) were recruited from an STD clinic. Patients reported their number of sexual partners; the male-to-female ratio per census tract was obtained from the U.S. Census Bureau. There were fewer men than women in nearly all census tracts. The interaction between gender and the male-to-female ratio was significant. For men, there was no association between the sex ratio and their number of sexual partners. For women, as the sex ratio increased, their number of sexual partners increased; however, this association was driven by participants who reported trading sex. We found no evidence that fewer African-American men in a census tract was associated with men having more sexual partners.
Asunto(s)
Negro o Afroamericano/estadística & datos numéricos , Infecciones por VIH/epidemiología , Heterosexualidad/estadística & datos numéricos , Parejas Sexuales , Enfermedades de Transmisión Sexual/epidemiología , Adulto , Negro o Afroamericano/psicología , Femenino , Infecciones por VIH/transmisión , Humanos , Modelos Logísticos , Masculino , Análisis Multinivel , Factores de Riesgo , Factores Sexuales , Enfermedades de Transmisión Sexual/transmisión , Factores Socioeconómicos , Estados Unidos/epidemiología , Adulto JovenRESUMEN
The purpose of this study was to evaluate the separate and combined effectiveness of brief and intensive interventions for sexual risk reduction among patients at a sexually transmitted disease (STD) clinic. Patients (N =1483; 54% men; 64% African-American; M = 29.2 years old) were recruited from a publicly funded, walk-in STD clinic. Patients completed a baseline assessment, and then were randomized to one of six intervention arms; each arm combined a brief intervention with an intensive intervention. The interventions provided different levels of information, motivational counseling, and behavioral skills training, guided by theory, formative research, and empiric precedent. Follow-up assessments, including STD screening, occurred at 3, 6, and 12 months post-intervention. The results showed that infection rates declined from 18.1% at baseline to 4.5% at 12 months. At a 3-month follow-up, patients reported fewer sexual partners, fewer episodes of unprotected sex, and a lower percentage of unprotected sexual events; they strengthened sexual health knowledge, safer sex attitudes and intentions, and self-efficacy beliefs. No consistent pattern of differential risk reduction was observed among the six intervention conditions, nor was any evidence of decay from 3 to 12-month follow-ups obtained. We conclude that implementing behavioral interventions in a STD clinic was associated with significant reduction of sexual risk behavior and risk antecedents.
Asunto(s)
Infecciones por VIH/prevención & control , Conducta de Reducción del Riesgo , Conducta Sexual , Enfermedades de Transmisión Sexual/prevención & control , Sexo Inseguro/prevención & control , Adulto , Negro o Afroamericano , Instituciones de Atención Ambulatoria , Femenino , Infecciones por VIH/epidemiología , Infecciones por VIH/etnología , Humanos , Masculino , Sexo Seguro , Enfermedades de Transmisión Sexual/epidemiología , Enfermedades de Transmisión Sexual/etnología , Resultado del TratamientoRESUMEN
OBJECTIVE: Research on the association between substance use and sexual risk behavior has yielded a complex pattern of findings. Such inconsistent findings may reflect method variance, including factors such as gender of the participant, nature of the sexual event, partner characteristics, and type of substance used. The purpose of this study was to investigate the association between substance use and unprotected sex independently for alcohol, drugs, or combined substance use and to examine partner characteristics as a moderator of this association. METHOD: Participants (N = 1,419; 48% women) were recruited from a publicly funded sexually transmitted disease clinic and were asked to complete an audio computer-assisted self-interview regarding their most recent sexual experience, including nature of the event, substance use, and partner characteristics. RESULTS: Analyses showed that alcohol use was related to condom use when gender and partner type were considered; thus, for women, but not for men, partner type interacted with alcohol consumption such that condom use was less likely when alcohol consumption preceded sex with nonprimary partners (drinking was unrelated to condom use with primary partners). Subsequent analyses examining partner substance use showed that women, but not men, who reported both they and their nonprimary partners were drinking during sex were less likely to use a condom. CONCLUSIONS: At the event level, alcohol consumption among sexually transmitted disease clinic patients is associated with condom use, but this association differs by gender and partner characteristics. Findings suggest the need to strengthen substance-use components in sexual risk reduction interventions for women and their partners.
Asunto(s)
Consumo de Bebidas Alcohólicas/epidemiología , Instituciones de Atención Ambulatoria , Condones , Conducta Anticonceptiva , Enfermedades de Transmisión Sexual/epidemiología , Trastornos Relacionados con Sustancias/epidemiología , Adulto , Consumo de Bebidas Alcohólicas/efectos adversos , Instituciones de Atención Ambulatoria/estadística & datos numéricos , Conducta Anticonceptiva/estadística & datos numéricos , Femenino , Humanos , Masculino , Factores de Riesgo , Conducta Sexual/estadística & datos numéricos , Enfermedades de Transmisión Sexual/etiología , Trastornos Relacionados con Sustancias/complicacionesRESUMEN
OBJECTIVE: The Centers for Disease Control and Prevention recommends that HIV testing be a standard part of medical care; however, testing is voluntary and some patients decline. We evaluated 2 brief interventions to promote rapid HIV testing among STD clinic patients who initially declined testing. METHOD: Using a randomized controlled trial, patients either viewed an educational digital video disc (DVD) or participated in stage-based behavioral counseling (SBC) provided by a nurse. Sixty clients presenting for care at a STD clinic who initially declined HIV testing at registration and during risk behavior screening participated in the study. RESULTS: The primary outcome was whether patients agreed to be tested for HIV. The secondary outcomes included attitudes, knowledge, and stage-of-change regarding HIV testing. Patients receiving both interventions improved their attitudes and knowledge about testing (ps < .01). Patients receiving SBC agreed to testing more often (45%) than did patients who viewed the DVD (19%; p < .05). CONCLUSIONS: Brief interventions can increase rapid HIV testing acceptance among patients who are reluctant to be tested; counseling guided by behavioral science theory is more effective than a well-designed information-based intervention.
Asunto(s)
Atención Ambulatoria/estadística & datos numéricos , Infecciones por VIH/diagnóstico , Infecciones por VIH/epidemiología , Tamizaje Masivo/métodos , Tamizaje Masivo/normas , Enfermedades de Transmisión Sexual/epidemiología , Adulto , Demografía , Femenino , Promoción de la Salud , Humanos , Masculino , Índice de Severidad de la EnfermedadRESUMEN
BACKGROUND: Sexually transmitted infection (STI) clinics provide an opportune setting for HIV prevention efforts. This randomized controlled trial evaluated a unique, two-step approach to sexual risk reduction at a publicly-funded STI clinic. METHODS: During an initial visit, patients completed an audio-computer assisted self-interview (ACASI), were randomized to and received one of two brief interventions, obtained medical care, and completed a post-assessment. Next, two-thirds of the patients were assigned to attend an intensive sexual risk reduction workshop. At 3, 6, and 12 months, patients completed additional ACASIs and provided urine specimens to assess behavior change and incident STIs. RESULTS: During a 28-month interval, 5613 patients were screened, 2691 were eligible, and 1483 consented to participate and were randomized; the modal reason for declining was lack of time (82%). Consenting patients included 688 women and 795 men; 64% of participants were African-American. The sample was low-income, with 57% reporting an annual income of less than $15,000; most participants (62%) had a high school education or less, and 51% were unemployed. Sexual risk behavior was common, as indicated by multiple sexual partners (mean=32.8, lifetime; mean=2.8, past 3 months), unprotected sex (mean=17.3 episodes, past 3 months), and prior STIs (mean=3.3, lifetime; 23% at baseline). Bivariate analyses confirmed our prediction that HIV-related motivation and behavioral skills would be related to current sexual risk behavior. All patients received a brief intervention; patient satisfaction ratings were uniformly high for both interventions (all means >or=3.7 on 4-point scales). Fifty-six percent of invited patients attended the intensive workshop, and attendance did not differ as a function of brief intervention. Patient satisfaction ratings were also uniformly positive for the workshop interventions (all means >or=3.6). Return to follow-up assessments exceeded 70%. CONCLUSIONS: Results demonstrate that implementing an HIV preventive program in a busy, public clinic is feasible and well-accepted by patients. Ongoing evaluation will determine if the interventions reduce sexual risk behavior and lower incident STIs.
Asunto(s)
Instituciones de Atención Ambulatoria , Infecciones por VIH/prevención & control , Asunción de Riesgos , Conducta Sexual , Enfermedades de Transmisión Sexual , Adulto , Femenino , Infecciones por VIH/epidemiología , Promoción de la Salud , Humanos , Masculino , Comercialización de los Servicios de Salud , New York/epidemiología , Satisfacción del Paciente , Factores de Riesgo , Conducta de Reducción del Riesgo , Enfermedades de Transmisión Sexual/epidemiología , Enfermedades de Transmisión Sexual/prevención & control , Encuestas y Cuestionarios , Estados Unidos/epidemiologíaRESUMEN
OBJECTIVES: This study determined whether patients from an STD clinic who agreed to participate in behavioral research are representative of the overall patient population. STUDY DESIGN: Patients attending an STD clinic (N = 2694) were invited to participate in sexual risk-reduction research. Those who accepted (consenters) were compared to those who declined (nonconsenters) on data obtained from the medical chart. RESULTS: Overall, 58% of eligible patients consented to participation. Logistic regression analyses indicated that consenting to participate was associated with female sex [odds ratio (OR) = 1.86], nonwhite race (OR = 2.16), having completed at least some college (OR = 1.70), being a returning patient (OR = 1.21), and having a greater number of sexual partners in the past 3 months (OR = 6.95) (all P's <0.05). CONCLUSIONS: Patients who agreed to participate had more education, were more familiar with the setting, and were more vulnerable to HIV/STD (as suggested by epidemiologic research). Efforts to enhance participation by an even greater percentage of patients might target these predictors of participation by enhancing risk awareness and providing preemptive reassurances regarding the research process and setting.
Asunto(s)
Selección de Paciente , Ensayos Clínicos Controlados Aleatorios como Asunto , Investigación , Asunción de Riesgos , Enfermedades de Transmisión Sexual/prevención & control , Adulto , Femenino , Humanos , Masculino , New YorkRESUMEN
Childhood sexual abuse (CSA) is associated with a wide range of negative outcomes. The authors investigated the relation between CSA and sexual risk behavior in 827 patients recruited from a sexually transmitted disease (STD) clinic. Overall, CSA was reported by 53% of women and 49% of men and was associated with greater sexual risk behavior, including more sexual partners, unprotected sex, and sex trading. Alcohol use for men and drug use for women mediated the relation between CSA and the number of sexual partners in the past 3 months; intimate partner violence mediated the relation between CSA and the number of episodes of unprotected sex in the past 3 months for women. These results document the prevalence of CSA among patients seeking care for an STD and can be used to tailor sexual risk reduction programs for individuals who were sexually abused.
Asunto(s)
Atención Ambulatoria/estadística & datos numéricos , Abuso Sexual Infantil/psicología , Abuso Sexual Infantil/estadística & datos numéricos , Conducta Sexual/psicología , Enfermedades de Transmisión Sexual/epidemiología , Enfermedades de Transmisión Sexual/terapia , Adulto , Niño , Femenino , Humanos , Masculino , PrevalenciaRESUMEN
Most patients attending urban STD clinics can benefit from workshops designed to promote sexual health and reduce sexual risk behaviors. However, many patients do not attend such workshops when invited. The purpose of this study was to evaluate the effects of providing a financial incentive on attendance at a sexual risk reduction workshop tailored to patients at an urban STD clinic. A quasi-experimental design with two conditions (incentive vs no incentive) was implemented sequentially with 107 STD clinic patients (58 men, 49 women; 69% African American; mean age = 27 years) reporting risky sexual behavior. Attendance at a subsequent sexual risk reduction workshop served as the key outcome. Results indicated that participants who were provided with a $30 cash incentive were more likely to attend the risk reduction workshop (38%) than participants who were not offered an incentive (9%), chi (1, N = 107) = 12.88, p < .001. Additional analyses confirmed that incentive (AOR = 7.59, p < .001) predicted attendance even after controlling for other significant predictors, namely, employment status (AOR = 3.04, p < .05) and age (AOR = 1.07, p < .05). We conclude that financial incentives are an effective way to increase attendance at sexual risk reduction workshops for at-risk urban populations.
Asunto(s)
Educación , Motivación , Selección de Paciente , Conducta de Reducción del Riesgo , Enfermedades de Transmisión Sexual/prevención & control , Adulto , Femenino , Humanos , Masculino , Conducta SexualAsunto(s)
Aspergilosis/complicaciones , Aspergillus niger/aislamiento & purificación , Virus de la Influenza A/aislamiento & purificación , Gripe Humana/complicaciones , Insuficiencia Respiratoria/etiología , Anciano , Anciano de 80 o más Años , Aspergilosis/diagnóstico , Resultado Fatal , Femenino , Fiebre/etiología , Humanos , Gripe Humana/diagnósticoRESUMEN
Legionella pneumophila is an important cause of community-acquired and nosocomial pneumonia. We describe an immunocompromised patient with severe pneumonia from whom Legionella species were isolated from sputum samples by culture for 30 days, despite administration of treatment with appropriate antimicrobial agents. However, clear improvement in the patient's respiratory condition was evident, and he subsequently recovered completely.