[Aspects of development of surgical service of modem Navy].

The article is devoted to the aspects of a current state of surgical service in the Navy, prospects of development of professianl training for navy surgeons, formation of modern training comlex, united electronic library, containig the issues about combat surgical trauma, software technologies, realizing of the application methodology during the process of training and practical activity for the development of the training system for surgeons of Navy and improvement of effectiveness. Formation of normative technical documents, regulating activity of navy surgians is also among the expectations. The authors also touched on the issues of development of modern technologies in bone grafting with the help of domestic implants based on the osteoinductive nanostructured nonorganic matrices (titanium) with defined structure and composition. Department of navy and hospital surgery participate in this debelopment. Due to increased amount of oncologic patients, it was decided to establish the Cancer Center of the Ministry of Defense based on department of navy and hospital surgery of the Kirov Military Medical Academy. It makes possible to perform the following procedures: canser surgery; surgical repair; plastic repair of major vessels, bone and soft tissue grafting, removal of residual cancer cells with the help of loco-regional methods of hyperthermic intracavitary and intravascular chemoperfusion; diagnostics and treatment of recurrent tumors (surgical and radiation treatment, systemic chemotherapy, loco-regional chemoembolization. Each of the given methods help to develop and improve the innovation technologies.

[Histological manifestations of the sparing effect of cooling in heat dissection of the cerebral cortex and liver]. / Gistologicheskie proiavleniia shchadiashchego éffekta kholodovoi zashchity pri teplovom rassechenii kory bol'shogo mozga i pecheni.

A new method of heat dissection of tissues combined with application of cooling was studied experimentally in white rats. Histologic changes of tissues of the cerebrum cortex and the liver wounds were investigated. It was found out that automatic selection of temperature regimen in combination of heat and cold ensured stable effect which was well balanced from the point of view of its depth and prevented overheating of tissues surrounding a wound channel. In comparison with cut wounds the above mentioned method allowed to gain better safety of cells.

[Cytophotometric evaluation of alkaline phosphatase activity in neutrophilic granulocytes and fibroblasts during wound healing in rats]. / Tsitofotometricheskaia otsenka aktivnosti shchelochnoi fosfatazy v neitrofil'nykh granulotsitakh i fibroblastakh pri zazhivlenii ran u krys.

The most informative indexes of alkaline phosphatase activity in neutrophil granulocytes from the peripheral blood and in neutrophil granulocytes and fibroblasts from the wound were defined in the experimental study carried out on 60 rats. These indexes were used to reveal the relationship between blood system reactions and inflammatory and regeneration processes in the wound tissue. The division of neutrophil granulocytes into three functional groups in accordance with alkaline phosphatase activity was demonstrated to be reasonable. The progress of inflammatory and regeneration processes in the wound tissues was shown to be adequately reflected in changes of both general and relative number of blood circulating neutrophil granulocytes of the third functional group characterized by high alkaline phosphatase activity. The results of the study demonstrate that the cytophotometric method is highly informative. It can be used in the clinical practice for an objective evaluation of the wound healing process as well as for an estimation of the treatment efficacy.