Desarrollo de un proceso participativo para el diagnóstico de salud comunitaria en estudiantes de la Universidad Miguel Hernández: Proyecto #beUMHealthy.

Los procesos participativos permiten analizar, comprender, debatir y promover la acción colectiva en asuntos significativos para una comunidad. Estas metodologías activas favorecen la identificación de necesidades y activos en salud para elaborar un diagnóstico de salud comunitaria y promover acciones colectivas. En este sentido, la aplicación de los procesos participativos en el contexto universitario resulta de gran interés para el fortalecimiento de las universidades como comunidades promotoras de la salud. En este trabajo se describe el desarrollo del proceso participativo #beUMHealthy, cuyo objetivo principal fue potenciar el debate sobre la salud y las iniciativas de promoción de la salud en el alumnado de la Universidad Miguel Hernández (UMH). El proyecto se desarrolló entre mayo y noviembre del 2019. Se recogieron 22 participaciones mediante WhatsApp y 173 cuestionarios diligenciados en línea. Este proceso permitió identificar necesidades y activos en salud en el alumnado de la UMH y obtener propuestas para su mejora. Esta información se usará para promover acciones futuras que incrementen la salud de la comunidad universitaria.

Fat: Quality, or Quantity? What Matters Most for the Progression of Metabolic Associated Fatty Liver Disease (MAFLD).

OBJECTIVES: Lately, many countries have restricted or even banned transfat, and palm oil has become a preferred replacement for food manufacturers. Whether palm oil is potentially an unhealthy food mainly due to its high content of saturated Palmitic Acid (PA) is a matter of debate. The aim of this study was to test whether qualitative aspects of diet such as levels of PA and the fat source are risk factors for Metabolic Syndrome (MS) and Metabolic Associated Fatty Liver Disease (MAFLD). METHODS: C57BL/6 male mice were fed for 14 weeks with three types of Western diet (WD): 1. LP-WD-low concentration of PA (main fat source-corn and soybean oils); 2. HP-WD-high concentration of PA (main fat source-palm oil); 3. HP-Trans-WD-high concentration of PA (mainly transfat). RESULTS: All types of WD caused weight gain, adipocyte enlargement, hepatomegaly, lipid metabolism alterations, and steatohepatitis. Feeding with HP diets led to more prominent obesity, hypercholesterolemia, stronger hepatic injury, and fibrosis. Only the feeding with HP-Trans-WD resulted in glucose intolerance and elevation of serum transaminases. Brief withdrawal of WDs reversed MS and signs of MAFLD. However, mild hepatic inflammation was still detectable in HP groups. CONCLUSIONS: HP and HP-Trans-WD play a crucial role in the genesis of MS and MAFLD.

Sleep Duration and Quality and Sensory Reactivity in School-Aged Children: The Spanish Cross-Sectional InProS Study.

Background: The relationship between children's sleep and health has been widely examined; however, research focused on the link between sleep and sensory reactivity in children without medical conditions is relatively new and based on studies with small samples. Hence, we aimed at exploring the association between sleep duration and quality and prevalence of sensory reactivity in a population-based sample of children aged 3-7. Methods: We examined data on 579 school-age children from the InProS project, a cross-sectional population-based study. Children's sleep duration was classified as <10 vs. ≥10 h/day, and sleep quality was measured using the Pediatric Sleep Questionnaire, defining poor quality sleep as a score of ≥0.33. The Short Sensory Profile (SSP) was used to classify children with or without sensory reactivity using the cut-off points proposed by W. Dunn for SSP total score and each SSP subscale. Prevalence ratios (PR) using Poisson multiple regression models with robust variance were estimated to examine main associations. Results: Around a third (32.6%; n = 189) slept <10 h/day and 10.4% presented poor sleep quality. The prevalence of sensory reactivity was 29.5% for total SSP (<155), 11.4% for tactile sensitivity (<30), 15% for taste/smell sensitivity (<15), 22.5% for movement sensitivity (<13), 49.1% for under-responsive/seeks sensation (<27), 44.4% for auditory filtering (<23), 12.4% for low energy/weak (<26), and 25.4% for visual/auditory sensitivity (<19). Main findings indicated that poor sleep quality was significantly associated with a greater prevalence of sensory reactivity for SSP total score (PR = 1.27; IC 95%: 1.18; 1.38), tactile sensitivity (PR = 1.09, IC95%: 1.00-1.19), taste/smell sensitivity (PR = 1.18, IC95%: 1.08-1.30), under-responsive/seeks sensation (PR = 1.28, IC95%: 1.20-1.37), auditory filtering (PR = 1.31, IC95%: 1.23-1.39), low energy/weak (PR = 1.14, IC95%: 1.04-1.25) and audiovisual sensitivity (PR = 1.15, IC95%: 1.05-1.26) scores after adjusting for potential confounders. Conclusions: In this study, we observed that poor sleep quality was statistically significantly associated with a higher prevalence of sensory reactivity as measured by the total SSP and almost all SSP subscales. To our knowledge, this is the first time that this association has been explored and reported. Further research from prospective studies is required to confirm these findings.

Popliteal artery: Anatomical study and review of the literature.

BACKGROUND: The frequency of appearance of anatomical variability in the terminal division of the popliteal artery (PA) is different according to the type of sample used, and ranges from 2% to 21%. The PA locates 1,01 cm behind to the lateral meniscus, which makes it vulnerable during surgical procedures. Iatrogenic injury of the PA or its terminal branches increases if anatomical variables are present. Our aim was to describe and review the branching pattern of the PA in a body-donors to science sample to determine the influence of the sample used (body-donors vs imaging test). METHODS: A sample consisting of 260 popliteal regions, corresponding to 130 corpses (66 women, 64 men), have been dissected. Multivariate analysis was carried out. RESULTS: The terminal division of the PA was classified as follows: Pattern 1: the PA divided into the anterior tibial (ATA) and the posterior tibial arteries (PTA) at the level or distal to the lower border of the popliteal muscle (PM) (94.7%). Pattern 2: the PA bifurcated into the ATA and PTA, proximal to the lower border of the PM (3.3%). Pattern 3: the PA divided at the same level into the ATA, PTA and PEA. (2%). No significant differences between gender and side of the limb could be find. CONCLUSIONS: We propose a classification that encloses three identifiable groups only. This will allow clinicians to bear in mind these variables easily, at the same time avoiding injuries during surgical procedures such as lateral meniscus repair.

Association between Body Mass Index and Sensory Processing in Childhood: InProS Study.

We assessed the association between body mass index (BMI) and sensory processing in 445 Spanish children aged 3-7 from the InProS project. Child sensory processing was measured using the short sensory profile (SSP); an atypical sensory performance was defined as an SSP total score <155 and scores of tactile sensitivity <30; taste/smell sensitivity <15; movement sensitivity <13; under-responsive/seeks sensation <27; auditory filtering <23; low energy/weak <26; and visual/auditory sensitivity <19. The BMI was calculated according to the cutoffs by the World Health Organization for children aged 0-5 and 5-19 years. We used multiple Poisson regression models with robust variance to obtain prevalence ratios (PR). No associations between children's overweight and obesity and the prevalence of atypical sensory outcomes were observed. A one-point increase in BMI was significantly associated with a higher prevalence of atypical tactile sensitivity (PR = 1.07, 95% CI: 1.02; 1.12). A statistically marginal association was also observed for atypical total SSP (PR = 1.03, 95% CI: 1.00; 1.07) and atypical movement sensitivity (PR = 1.05, 95% CI: 1.00; 1.10). To our knowledge, this is the first time the association between children's BMI and sensory processing has been reported. Our findings suggest that sensory processing issues may play a part in the complex context of childhood obesity. Further research is required to confirm these findings.

Vascular clinical anatomy of the submandibular gland.

OBJECTIVE: The aim of this study is to describe in depth the precise anatomy of the vascular supply of the submandibular gland, trying to determine the existence of patterns of glandular vascularization. Knowledge of these patterns could facilitate surgical management of the gland and the submandibular gland flap. MATERIAL AND METHODS: Neck dissections of formaldehyde preserved human cadavers were performed. Submandibular and transmandibular approaches were used during the dissections. All the vascular branches found were registered and classified into 2groups: main or accessory branches. The anatomical data analyzed was: The diameter and length of the main and accessory branches, as well as the most important measurements of the submandibular gland flap pedicle. RESULTS: 33 glands were dissected to study the arterial supply of the submandibular gland (17 right, 16 left; 17 males, 16 females) and 29 were dissected to study the venous supply (15 left, 14 right; 15 males,14 females). A total of 123 arterial branches were found reaching the 33 submandibular glands (47 main and 76 accessories) and 116 venous branches were found draining the 29 submandibular glands (47 main branches and 69 accessory branches). A constant main venous branch that ran parallel to the Wharton duct and drained in the sublingual vein was found in all of cases (Concomitant Wharton Duct Vein or CWDV). CONCLUSION: The CWDV is a constant venous branch for the drainage of the gland and should be considered as venous pedicle during the dissection of submandibular gland flaps.

Alcoholic liver disease: Utility of animal models.

Alcoholic liver disease (ALD) is a major cause of acute and chronic liver injury. Extensive evidence has been accumulated on the pathological process of ALD during the past decades. However, effective treatment options for ALD are very limited due to the lack of suitable in vivo models that recapitulate the full spectrum of ALD. Experimental animal models of ALD, particularly rodents, have been used extensively to mimic human ALD. An ideal animal model should recapitulate all aspects of the ALD process, including significant steatosis, hepatic neutrophil infiltration, and liver injury. A better strategy against ALD depends on clear diagnostic biomarkers, accurate predictor(s) of its progression and new therapeutic approaches to modulate stop or even reverse the disease. Numerous models employing rodent animals have been established in the last decades to investigate the effects of acute and chronic alcohol exposure on the initiation and progression of ALD. Although significant progress has been made in gaining better knowledge on the mechanisms and pathology of ALD, many features of ALD are unknown, and require further investigation, ideally with improved animal models that more effectively mimic human ALD. Although differences in the degree and stages of alcoholic liver injury inevitably exist between animal models and human ALD, the acquisition and translational relevance will be greatly enhanced with the development of new and improved animal models of ALD.

Alternativa al cierre de heridas crónicas mediante injertos de Reverdin y factores de crecimiento en cirugía menor ambulatoria / Alternative to chronic wound closure by Reverdin grafts and growth factors in ambulatory surgery minor

El cierre de heridas crónicas supone una alta tasa en cuidados de enfermería, sobre todo en heridas de difícil cicatrización, debido a la falta de respuesta a los tratamientos aplicados y a la elevada prevalencia del proceso. Es necesario encontrar un método que reduzca el tiempo de curación, evite las complicaciones inherentes al cierre por cura húmeda convencional y pueda realizarse con los recursos disponibles en cualquier medio sanitario. El plasma rico en plaquetas (PRP) autólogo se utiliza actualmente como alternativa a la infiltración tradicional con corticoesteroides o en estado gel, en la cobertura o relleno de una determinada zona con pérdida de tejido. El presente estudio combina el uso de PRP e injertos insulares descritos por Reverdin (1869), en 15 individuos que presentan traumatismos con pérdida de sustancia que no responden a la cura húmeda convencional. Los resultados muestran que, tras la primera aplicación de PRP, se aprecia la aparición de tejido de granulación, que es susceptible de recibir el injerto. La combinación de ambas técnicas acorta el período de cicatrización de las heridas tratadas, con equipos de fácil accesibilidad en cualquier centro sanitario, minimizando costes con una expectativa de curación elevada, sumado al procedimiento fácilmente asumible por el personal de enfermería dedicado a cirugía menor ambulatoria

The closure of chronic wounds by secondary intention, is a high rate of nursing, especially in poorly healing wounds, for two main reasons, the lack of response to treatments, and the prevalence of this appeal process as claimed in primary health care centers and outpatient hospital. Also, the patient can lead to a delay in their total healing (medical discharge), which sometimes induce other incidents such as ambulance, delay in job placement, etc. It is necessary to find a method which reduces healing time in these cases and at the same time, avoid the complications inherent to conventional wet cure closing and in turn, be available to the media and resources available on our health system. The application of Platelets Rich Plasma (PRP), obtained by centrifugation of blood drawn directly to the patient, has been running for nearly twenty years in the health care setting. It is currently used as an alternative to traditional infiltration corticosteroid tendinopathies in gel state or as a clot, equivalent to a mesh of fibrin membranes capable of forming, filling in coverage or a particular area of tissue loss. Already in 1869, coined the term Reverdin island of skin grafts, initially in treating injury due to burns. In this technique, the wound is covered partially with small fragments of healthy skin of the patient. This study combines the use of PRP and slips island, applied in 15 individuals with trauma with loss of substance, no relevant medical history and do not respond to conventional wet cure. The results show that after the first application of the gel of PRP shows the appearance of granulation tissue, which is susceptible to grafting or island nested. The combination of both techniques shortens the healing time of wounds treated with equipment that is easily accessible in any health center, which is a very low level of spending and an expectation of success High cure, plus the procedure easily manageable by the nursing staff dedicated to program minor outpatient surgery

[Treatment of chronic anal fissure]. / Tratamiento de la fisura anal crónica.

Chronic anal fissure is a common benign anorectal problem in Western countries that substantially impairs the patient's life. Consequently, a rapid and effective solution is required. We reviewed the various treatments for chronic anal fissure described in the literature, with the aim of establishing a therapeutic protocol. We recommend surgical sphincterotomy (preferably open or closed lateral sphincterotomy) as the first therapeutic approach in patients with chronic anal fissure. However, we prefer the use of chemical sphincterotomy (preferably botulinum toxin) in patients aged more than 50 years old and in those with previous incontinence, risk factors for incontinence (previous anal surgery, multiple vaginal births, diabetes, inflammatory bowel disease, etc.), or without anal hypertonia, despite the higher recurrence rate with medical treatments, since this procedure avoids the greater risk of residual incontinence described in the literature with surgical sphincterotomy in this group of patients.