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1.
Rev. clín. esp. (Ed. impr.) ; 218(3): 115-120, abr. 2018. tab
Artículo en Español | IBECS | ID: ibc-174240

RESUMEN

Objetivos. Blastocystis hominis (B. hominis) es uno de los parásitos intestinales más frecuentemente aislados en el ser humano. Puede producir sintomatología gastrointestinal o, en la mayoría de los casos, permanecer asintomático. Existen dudas sobre el carácter patógeno del parásito. El objetivo de este estudio fue analizar las características clínicas y epidemiológicas de la parasitación por B. hominis, con y sin otras coparasitaciones. Pacientes y métodos. Estudio observacional retrospectivo de aislamientos de B. hominis en heces, desde octubre del 2004 hasta marzo del 2016 en una Unidad de Medicina Tropical. Se revisó a todos los pacientes con parasitación exclusiva, o no, por B. hominis. Resultados. Se estudió a 3.070 pacientes. En 570 (18%) se diagnosticó infección por B. hominis, de los que en 245 (43%) representó el único aislamiento; 325 (57%) presentaron otras coparasitaciones (Entamoeba hystolitica o dispar, Strongyloides stercoralis, uncinarias y Schistosoma sp.). El síntoma principal fue dolor abdominal (41,8%). En un 31,2% el parásito se detectó en el cribado de enfermedades importadas en pacientes asintomáticos. De los que recibieron tratamiento con metronidazol, un 78,2% mejoró y en el 82,6% los parásitos se negativizaron. Conclusiones. La parasitación por B. hominis es una de las enfermedades más frecuentes en nuestra Unidad de Medicina Tropical. La mayoría de los pacientes están asintomáticos o bien la clínica puede ser atribuida a otras parasitaciones. En aquellos casos en los que persisten los síntomas sin poder ser atribuidos a otras causas, es recomendable un tratamiento específico


Objectives. Blastocystis hominis (B. hominis) is one of the most common intestinal parasites isolated in humans. The parasite can cause gastrointestinal symptoms or, in most cases, remain asymptomatic. There are issues concerning the parasite's pathogenic character. The aim of this study was to analyse the clinical and epidemiological characteristics of the parasite infection by B. hominis, with or without other parasitic co-infections. Patients and methods. An observational retrospective study was conducted of B. hominis isolates in faeces from October 2004 to March 2016 in a tropical medicine unit. We reviewed all patients with a parasite infection, exclusively or not by B. hominis. Results. We studied 3070 patients, 570 (18%) of whom were diagnosed with B. hominis infection, which was the only isolate in 245 (43%) of the 570 patients. A total of 325 (57%) patients presented other parasitic co-infections (Entamoeba histolytic or Entamoeba dispar, Strongyloides stercoralis, hookworm and Schistosoma spp.). The main symptom was abdominal pain (41.8%). In 31.2% of cases, the parasite was detected in the imported diseases screening of asymptomatic patients. Of those who underwent treatment with metronidazole, 78.2% improved. The parasite was neutralised in 82.6% of the patients. Conclusions. Parasite infection by B. hominis is one of the most common diseases in our tropical medicine unit. Most patients are asymptomatic, or their symptoms can be attributed to other parasite infections. In those cases in which symptoms persist without being able to attribute them to other causes, a specific treatment is recommended


Asunto(s)
Humanos , Masculino , Femenino , Preescolar , Niño , Adolescente , Adulto Joven , Adulto , Persona de Mediana Edad , Anciano , Parasitosis Intestinales/epidemiología , Infecciones por Blastocystis/epidemiología , Blastocystis hominis/aislamiento & purificación , Metronidazol/uso terapéutico , Dolor Abdominal/etiología , Combinación Trimetoprim y Sulfametoxazol/uso terapéutico , Estudios Retrospectivos , Parasitosis Intestinales/tratamiento farmacológico , Anamnesis/métodos , Parasitosis Intestinales/orina , Esquistosomiasis/orina , Microfilarias , Microfilarias/parasitología , España/epidemiología , Heces/parasitología
2.
Rev Clin Esp (Barc) ; 218(3): 115-120, 2018 Apr.
Artículo en Inglés, Español | MEDLINE | ID: mdl-29455921

RESUMEN

OBJECTIVES: Blastocystis hominis (B. hominis) is one of the most common intestinal parasites isolated in humans. The parasite can cause gastrointestinal symptoms or, in most cases, remain asymptomatic. There are issues concerning the parasite's pathogenic character. The aim of this study was to analyse the clinical and epidemiological characteristics of the parasite infection by B. hominis, with or without other parasitic co-infections. PATIENTS AND METHODS: An observational retrospective study was conducted of B. hominis isolates in faeces from October 2004 to March 2016 in a tropical medicine unit. We reviewed all patients with a parasite infection, exclusively or not by B. hominis. RESULTS: We studied 3070 patients, 570 (18%) of whom were diagnosed with B. hominis infection, which was the only isolate in 245 (43%) of the 570 patients. A total of 325 (57%) patients presented other parasitic co-infections (Entamoeba histolytic or Entamoeba dispar, Strongyloides stercoralis, hookworm and Schistosoma spp.). The main symptom was abdominal pain (41.8%). In 31.2% of cases, the parasite was detected in the imported diseases screening of asymptomatic patients. Of those who underwent treatment with metronidazole, 78.2% improved. The parasite was neutralised in 82.6% of the patients. CONCLUSIONS: Parasite infection by B. hominis is one of the most common diseases in our tropical medicine unit. Most patients are asymptomatic, or their symptoms can be attributed to other parasite infections. In those cases in which symptoms persist without being able to attribute them to other causes, a specific treatment is recommended.

3.
Rev. clín. esp. (Ed. impr.) ; 216(5): 248-252, jun.-jul. 2016. tab
Artículo en Español | IBECS | ID: ibc-153374

RESUMEN

Introducción. Las hepatitis virales representan un importante problema de salud en los países africanos. El incremento de la población inmigrante procedente de este continente supone un reto para el sistema sanitario. Material y métodos. Estudio descriptivo sobre la prevalencia de marcadores serológicos de hepatitis viral B (VHB), C (VHC) y delta (VHD) en inmigrantes africanos atendidos en una consulta especializada. Resultados. Se incluyó a 2.518 pacientes (87,7% subsaharianos) con una edad media de 31,3 años. El 78,8% presentó algún marcador positivo de infección por el VHB y en 638 pacientes (25,3%) se diagnosticó una hepatitis B activa (AgHBs+). En 19 casos se detectaron anticuerpos frente al VHD (4 con detección del genoma viral). Sesenta y ocho pacientes presentaron anticuerpos contra el VHC, de los que 26 tenían carga viral positiva. Conclusiones. La elevada prevalencia de hepatitis virales en inmigrantes, en especial la infección por VHB, ha supuesto un cambio significativo en el perfil de pacientes atendidos en nuestro país, y precisa de medidas encaminadas a un diagnóstico precoz y prevención de la transmisión (AU)


Background. Viral hepatitis is a significant health problem in African countries. The increase in the immigrant population from this continent represents a challenge for the Spanish healthcare system. Material and methods. A descriptive study was conducted on the prevalence of the serological markers of hepatitis B (HBV), C (HCV) and D (HDV) in African immigrants treated in a specialised doctor's office. Results. The study included 2518 patients (87.7% Sub-Saharan natives), with a mean age of 31.3 years. Some 78.8% of the patients had a positive infection marker for HBV, and 638 patients (25.3%) were diagnosed with active hepatitis B (HBsAg +). In 19 cases, antibodies against HDV were detected (4 cases with detection of the viral genome). Sixty-eight patients had antibodies against HCV, 26 of whom had a positive viral load. Conclusions. The high prevalence of viral hepatitis in immigrants, especially HBV infection, represents a significant change in the profile of patients treated in Spain and requires measures aimed at early diagnosis and transmission prevention (AU)


Asunto(s)
Humanos , Masculino , Femenino , Adulto , Hepatitis C/epidemiología , Hepatitis A/epidemiología , Hepatitis B/epidemiología , Hepatitis Viral Humana/epidemiología , Emigrantes e Inmigrantes/estadística & datos numéricos , Sistemas de Salud/organización & administración , Sistemas de Salud/tendencias , Biomarcadores/análisis , Pruebas Serológicas/métodos , Pruebas Serológicas/tendencias , Diagnóstico Precoz , Hibridación in Situ/métodos , Viremia/diagnóstico , Viremia/epidemiología , Salud Pública/métodos , Salud Pública/tendencias , Monitoreo Epidemiológico/organización & administración , Monitoreo Epidemiológico/estadística & datos numéricos , Monitoreo Epidemiológico/normas
4.
Eur J Clin Microbiol Infect Dis ; 35(9): 1487-93, 2016 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-27272213

RESUMEN

Schistosomiasis is related to the development of liver fibrosis and portal hypertension. Chronic co-infection with HBV and Schistosoma has been associated in endemic areas with a higher risk for a more severe liver disease. However, no studies have assessed the real importance of this co-infection in non-endemic regions. This is a retrospective observational study of Sub-Saharan immigrants attending between October 2004 and February 2014. Patients with chronic HBV infection with and without evidence of schistosomal infection were compared. Epidemiological, analytical, and microbiological data were analysed. Likelihood of liver fibrosis based on APRI and FIB-4 indexes was established. A total of 507 patients were included in the study, 170 (33.5 %) of them harbouring evidence of schistosome infection. No differences were found in transaminase, GGT, and ALP levels. In fibrosis tests, a higher proportion of patients with HVB and S. mansoni detection reached possible fibrosis scores (F > 2) when compared to patients without schistosomiasis: 17.4 vs 14.2 % and 4.3 % vs 4.2 % (using high sensitivity and high specificity cut-offs respectively), although differences were not statistically significant (p = 0.69, p = 0.96). For possible cirrhosis (F4) score, similar results were observed: 4.3 % of co-infected patients vs 2.1 % of mono-infected ones, p = 0.46. According to these datas, in non-endemic regions the degree of hepatic fibrosis in patients with chronic hepatitis B is not substantially modified by schistosome co-infection.


Asunto(s)
Coinfección/diagnóstico , Hepatitis B Crónica/complicaciones , Hepatitis B Crónica/diagnóstico , Esquistosomiasis/complicaciones , Esquistosomiasis/diagnóstico , Adulto , África del Sur del Sahara , Animales , Coinfección/epidemiología , Coinfección/patología , Emigrantes e Inmigrantes , Femenino , Hepatitis B Crónica/epidemiología , Hepatitis B Crónica/patología , Humanos , Cirrosis Hepática/diagnóstico , Cirrosis Hepática/epidemiología , Cirrosis Hepática/patología , Masculino , Estudios Retrospectivos , Esquistosomiasis/epidemiología , Esquistosomiasis/patología , España/epidemiología , Adulto Joven
5.
Rev Clin Esp (Barc) ; 216(5): 248-52, 2016.
Artículo en Inglés, Español | MEDLINE | ID: mdl-26995326

RESUMEN

BACKGROUND: Viral hepatitis is a significant health problem in African countries. The increase in the immigrant population from this continent represents a challenge for the Spanish healthcare system. MATERIAL AND METHODS: A descriptive study was conducted on the prevalence of the serological markers of hepatitis B (HBV), C (HCV) and D (HDV) in African immigrants treated in a specialised doctor's office. RESULTS: The study included 2518 patients (87.7% Sub-Saharan natives), with a mean age of 31.3 years. Some 78.8% of the patients had a positive infection marker for HBV, and 638 patients (25.3%) were diagnosed with active hepatitis B (HBsAg +). In 19 cases, antibodies against HDV were detected (4 cases with detection of the viral genome). Sixty-eight patients had antibodies against HCV, 26 of whom had a positive viral load. CONCLUSIONS: The high prevalence of viral hepatitis in immigrants, especially HBV infection, represents a significant change in the profile of patients treated in Spain and requires measures aimed at early diagnosis and transmission prevention.

12.
Aten Primaria ; 13(1): 31-4, 1994 Jan.
Artículo en Español | MEDLINE | ID: mdl-8136444

RESUMEN

OBJECTIVE: To show the present spread of brucellosis in Almeriá Province. DESIGN: Retrospective descriptive study. SETTING: Torrecárdenas Hospital, Almería. PATIENTS AND OTHER PARTICIPANTS: 137 cases of brucellosis diagnosed between 1988 and 1990 in Almería province. Study of individualised statements. MEASUREMENTS AND MAIN RESULTS: The incidence of brucellosis in Almería was 0.25, 2.25 and 3.07 times greater than that in the rest of the Spain during the years under study. 70.80% of cases came from the rural environment. 70.80% were declared in the spring-summer months. 67.88% of patients were male. 7.29% were paediatric cases. 42.31% belonged to a profession considered at risk. The means of infection was indirect in 46.71% of cases. The number of relapses was 10.21%. 3.64% were family cases. CONCLUSIONS: Brucellosis is endemic in the province of Almería. The situation shows no sign of improvement, because the hygienic-sanitary controls covering both dairy products for consumption and those professionals at risk are deficient.


Asunto(s)
Brucelosis/epidemiología , Adolescente , Adulto , Distribución por Edad , Anciano , Brucelosis/transmisión , Niño , Femenino , Humanos , Incidencia , Masculino , Persona de Mediana Edad , Recurrencia , Estudios Retrospectivos , Factores de Riesgo , Distribución por Sexo , España/epidemiología
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