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Background: Kartagener's syndrome, a rare autosomal recessive genetic disorder, is characterized by primary ciliary dyskinesia (PCD), resulting in defective cilia function in the respiratory tract and fallopian tubes. Case presentation: This case report discusses a 23-year-old female with Kartagener's syndrome, bronchiectasis, and cardiac involvement, who presented with shortness of breath, cough, and syncope. Notably, she received home oxygen therapy but became exhausted, leading to loss of consciousness. Clinical examination revealed prominent heart sounds and abnormal lung findings. Laboratory results indicated leukocytosis, and an ECG confirmed dextrocardia and cardiac abnormalities. Doppler studies identified mitral and tricuspid regurgitation along with severe pulmonary arterial hypertension. Antibiotics were administered for coagulase-negative Staphylococcus infection. The patient improved with a treatment regimen, including oxygenation and nebulization. Regular follow-up and patient education were emphasized. Conclusion: This case underscores the complexity of Kartagener's syndrome and the importance of a multidisciplinary approach in managing its respiratory and cardiac manifestations.
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Cite this article as: Vaid R, Fareed A. Colorful perspectives: Bridging the gap between marketing influences and pediatric medication adherence. Turk Arch Pediatr. Published online May 6, 2024. doi: 10.5152/TurkArchPediatr.2024.24027.
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Adenovirus, a common respiratory pathogen, has witnessed a notable rise in incidence rates across various regions in Pakistan. Utilizing epidemiological data and climate records, this research discerns a potential linkage between the burgeoning adenovirus cases and alterations in regional climate patterns. Through statistical analysis and modeling techniques, the study aims to elucidate the relationship between climatic variables, such as temperature, humidity, and precipitation, and the prevalence of adenovirus infections. Understanding these dynamics is crucial for developing effective public health interventions and preparedness strategies to mitigate the impact of adenovirus outbreaks in Pakistan. Furthermore, this research contributes to the broader discourse on the intersection of infectious diseases and climate change, highlighting the need for comprehensive adaptive measures to address emerging health challenges in a changing environment.
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Infecciones por Adenoviridae , Adenoviridae , Humanos , Adenoviridae/genética , Pakistán/epidemiología , Salud Pública , Brotes de Enfermedades/prevención & control , Infecciones por Adenoviridae/epidemiología , Infecciones por Adenoviridae/prevención & controlRESUMEN
Despite the life-saving nature of colorectal surgeries, patients often experience intra and post-operative problems, especially pain and discomfort. This meta-analysis aimed to evaluate the effectiveness of erector spinae plane block (ESP block) in postoperative pain management for patients undergoing colorectal surgeries. A comprehensive systematic literature search was conducted in PubMed and Cochrane Library databases from inception until December 2023. Eight studies were deemed appropriate for inclusion. The pooled analysis demonstrated a significant decrease with the ESP block compared to the control group in postoperative opioid consumption [MD â= â-15.96 âmg; 95 â% CI (-28.74 to -3.18); p â= â0.014, I2 â= â87 â%], intraoperative opioid consumption [MD â= â-35.51 âmg; 95 â% CI (-62.63 to -8.40); p â= â0.010, I2 â= â87 â%], pain scores [MD â= â-0.94; 95 â% CI (-1.27 to -0.60); p â< â0.000001, I2 â= â86 â%], with a significantly shorter duration of hospital stay [MD â= â-1.25 days; 95 â% CI (-2.02 to -0.48); p â= â0.002, I2 â= â23 â%]. This meta-analysis support the use of erector spinae plane block (ESP) for postoperative pain management in colorectal surgeries. ESP shows significant reductions in opioid consumption, pain scores and hospital stay.
