[Antituberculosis antibodies in patients with tuberculosis during chemotherapy]. / Protivotuberkuleznye antitela u bol'nykh tuberkulezom legkikh v protsesse khimioterapii.

Enzyme immunoassay of the titer of antituberculosis antibodies (ATAb) from patients with pulmonary tuberculosis has indicated that their levels depend on the different characteristics of a specific process: the form of active tuberculosis, the extent of changes in the lung tissue, the presence of destruction and bacterial isolation, the type of specific inflammatory reaction, and the duration of the treatment performed. Whether there was a correlation of ATAb titers with skin tuberculin sensitivity the level was studied by the Mantoux test using 2 TE PPD-L. The time course of changes in ATAb titers in patients with pulmonary tuberculosis during the routine chemotherapy was analyzed.

[Pathogenesis of osteochondrosis]. / K patogenezu osteokhondroza.

Osteochondrosis may present as a separate disease or be one of the stages of a dystrophic process coursing in the presence of cartilagenous nodes of deforming spondylosis. Primary or secondary dystrophic involvement of the nucleus pulposus may eventuate in the disk fibrosis.

[The first experience with using autologous macrophages in the complex treatment of patients with destructive pulmonary tuberculosis]. / Pervyi opyt primeneniia autologichnykh makrofagov v kompleksnom lechenii bol'nykh destruktivnym tuberkulezom legkikh.

To correct local immunity, a suspension of autologous macrophages (AM) produced by culturing peripheral blood monocytes has been introduced in combined treatment of 15 patients with infiltrative, local disseminated, cavernous, fibrocavernous tuberculosis and tuberculoma (8, 1, 1, 4 and 1 case, respectively). AM treatment was added to the standard antibacterial and pathogenetic therapy. AM were introduced into the subsegmental bronchus at fibrobronchoscopy via a catheter inserted into the cavern-draining bronchus. The trial showed AM-promoted resolution of pulmonary tissue infiltrates and more intensive repair processes. The best results were obtained in 11 new-onset cases of pulmonary tuberculosis.