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1.
J Craniofac Surg ; 34(7): 2121-2123, 2023 Oct 01.
Artículo en Inglés | MEDLINE | ID: mdl-37431923

RESUMEN

AIM: The aim of the present study was to evaluate the efficacy of modified lacrimal gland suspension surgery combined with upper lid blepharoplasty. METHODS: Between December 2020 and December 2021, 365 patients admitted to our clinic for ptosis were included in the study. The data of 89 patients who underwent upper lid blepharoplasty with lacrimal gland repositioning for dermatochalasis were analyzed. RESULTS: Combined surgery was performed in 24.38% of the patients included in the study; 16 (17.9%) of these patients were males and 73 (82.1%) were females, and the mean age of the patients was 47.34 ± 8.13 years. The mean follow-up period was 16.42 ± 2.63 months. In patients who underwent lacrimal gland suspension, 72 (85%) of the patients complained of swelling on the outer part of the upper lid before surgery. However, 9 (10.11%) of the patients did not have lacrimal gland prolapse, and only fat prolapse was present in these patients. No complication or recurrence was observed in any patient during the follow-up period. DISCUSSION: With the new modified technique, the lacrimal gland can be suspended close to the anatomical position, and satisfactory results can be obtained for both the patient and the surgeon.


Asunto(s)
Blefaroplastia , Blefaroptosis , Aparato Lagrimal , Masculino , Femenino , Humanos , Adulto , Persona de Mediana Edad , Blefaroplastia/métodos , Aparato Lagrimal/cirugía , Párpados/cirugía , Blefaroptosis/cirugía , Prolapso , Estudios Retrospectivos
2.
J Craniofac Surg ; 34(3): e216-e218, 2023 May 01.
Artículo en Inglés | MEDLINE | ID: mdl-36195986

RESUMEN

The aim of the present study is to evaluate the success of mucosa-sparing surgery with a modified inverted U flap in endoscopic dacryocystorhinostomy (E-DCR). Forty-two patients who underwent E-DCR without mucosal flap were included in group 1, and 41 patients who underwent E-DCR with modified inverted U mucosal flap technique were included in group 2. The patients were followed up for at least 12 months postoperatively, and the complications and functional success in both groups were analyzed comparatively. The functional success rate was 81% in group 1 and 95.1% in group 2. The difference between the 2 groups is statistically significant ( P =0.04). Postoperative granulation tissue development was observed in 9 patients (20.4%) in group 1 and in 2 patients (4.88%) in group 2, and the difference was statistically significant ( P =0.02). Mucosa-sparing E-DCR with modified inverted U flap achieves higher functional success than flapless surgery and causes less granulation formation.


Asunto(s)
Dacriocistorrinostomía , Conducto Nasolagrimal , Humanos , Dacriocistorrinostomía/métodos , Mucosa Nasal/cirugía , Tejido de Granulación , Colgajos Quirúrgicos , Periodo Posoperatorio , Endoscopía/métodos , Resultado del Tratamiento , Conducto Nasolagrimal/cirugía
3.
Beyoglu Eye J ; 7(3): 188-192, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-36185984

RESUMEN

Objectives: The aim of this study is to investigate the relationship between pseudoexfoliation syndrome (XFS) and pseudoexfoliative glaucoma (XFG) and endothelial nitric oxide synthase (eNOS) G894T polymorphism. Methods: Seventy-eight eyes of 78 patients who had undergone uncomplicated cataract surgeries for senile cataract were included in this study. Forty patients with XFS were included in the study group, and 38 patients without XFS constituted the control group. Patients with XFS were divided into two subgroups according to their XFG development, and subgroup analysis was performed. Venous blood samples were taken from all patients before surgery and 894 G>T (rs1799983) polymorphism on the eNOS gene was evaluated by RT-PCR. Results: While the mean age in the control group was 65.97±10.64 years (23 males and 15 females), the mean age in the study group was 73.05±6.79 years (30 males and 10 females), (p<0.001). Regression analysis of the risks caused by the genotype and alleles between the control and study groups revealed that the homozygous alleles were more common in the study group, and heterozygous or mutant alleles have reduced the development of XFS approximately 2-folds. However, this was not statistically significant (p=0.11). Similarly, when subgroup analysis was performed, it was found that there was no significant relationship between XFG in patients with XFS and gene polymorphism. Conclusion: In this study, it was observed that there was no relationship between the G894T polymorphism in the eNOS gene and the development of XFS/XFG.

4.
Arq. bras. oftalmol ; 85(3): 223-228, May-June 2022. tab, graf
Artículo en Inglés | LILACS-Express | LILACS | ID: biblio-1383802

RESUMEN

ABSTRACT Purpose: To compare the learning curves of the specialists in two different fields without previous endoscopic endonasal dacryocystorhinostomy experience as well as to reveal the related complications with surgical success rates. Methods: We retrospectively investigated 90 patients who received consecutive endoscopic endonasal dacryocystorhinostomy with mucosa preservation by an ophthalmologist (Group 1, n=45) and an otorhinolaryngologist (Group 2, n=45) between October 2017 and October 2019. Patients who were admitted with epiphora complaints and diagnosed with primary acquired nasolacrimal duct obstruction through lacrimal irrigation test and aged >18 years with at least 6 months of follow-up were included in the study. In all cases, additional pathologies such as septum deviation were evaluated by performing maxillofacial imaging. Patients' medical records were evaluated in terms of surgery duration, complications, and functional achievements. Results: The mean surgical duration of the patients in Group-2 was 36.27 ± 11.61 min, while it was 43.62 ± 16.89 min in Group-1; the difference was statistically significant (p=0.018). Functional achievements in Group 1 was 84.4% (73.3% in the first set of 15 cases, 93.3% in the last set of 15 cases) in Group 2; this rate was 88.9% (80% in the first set of 15 cases, 93.3% in the last set of 15 cases), and the difference was not statistically significant (p=0.53). Septum intervention in addition to endoscopic surgery in both the groups (p=0.03, p=0.005, respectively) and intense bleeding during surgery (for both the groups, p<0.0001) significantly decreased the functional success. Conclusion: Endoscopic endonasal dacryocystorhinostomy, performed after the necessary training, can provide high success and low complication rates when even conducted by ophthalmologists who are unfamiliar with endoscopic surgery after an experience of 30 cases.


RESUMO Objetivos: O objetivo deste estudo é comparar as curvas de aprendizagem dos especialistas em dois campos diferentes sem experiência prévia de dacriocistorrinostomia endonasal endoscópica e revelar as complicações com as taxas de sucesso cirúrgico. Métodos: Foram investigados retrospectivamente 90 pacientes que receberam dacriocistorrinostomia endonasal endoscópica consecutiva com preservação da mucosa realizada por um oftalmologista (Grupo 1, n=45) e realizada por um otorrinolaringologista (Grupo 2, n=45) entre outubro de 2017 e outubro de 2019. Foram incluídos no estudo pacientes admitidos com epífora e diagnosticados com obstrução primária do ducto nasolacrimal adquirido como resultado do teste de irrigação lacrimal, com idade superior a 18 anos e com, pelo menos, 6 meses de acompanhamento. Em todos os casos, patologias adicionais, como o desvio do septo, foram avaliadas por meio da realização de imagens maxilofaciais. Os prontuários dos pacientes foram avaliados quanto à duração da cirurgia, complicações e desempenho funcional. Resultados: A média de duração cirúrgica dos pacientes no Grupo-2 foi de 36,27 ± 11,61 minutos, enquanto no Grupo-1 foi de 43,62 ± 16,89 minutos, sendo a diferença estatisticamente significativa (p=0,018). O desempenho funcional no Grupo 1 foi de 84,4% (73,3% nos primeiros 15 casos, 93,3% nos últimos 15 casos) no Grupo 2, essa taxa foi de 88,9% (80% nos primeiros 15 casos, 93,3% nos últimos 15 casos) e a diferença não foi estatisticamente significativa (p=0,53). A intervenção do septo além da cirurgia endoscópica em ambos os grupos (p=0,03, p=0,005, respectivamente) e sangramento intenso durante a cirurgia (para ambos os grupos, p<0,0001) diminuiu significativamente o sucesso funcional. Conclusão: A dacriocistorrinostomia endonasal endoscópica, realizada após o treinamento necessário, pode ser realizada com alto sucesso e com baixas taxas de complicações por oftalmologistas que não estão familiarizados com a cirurgia endoscópica após adquirirem experiência com trinta casos.

5.
Arq Bras Oftalmol ; 85(3): 223-228, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-34586231

RESUMEN

PURPOSE: To compare the learning curves of the specialists in two different fields without previous endoscopic endonasal dacryocystorhinostomy experience as well as to reveal the related complications with surgical success rates. METHODS: We retrospectively investigated 90 patients who received consecutive endoscopic endonasal dacryocystorhinostomy with mucosa preservation by an ophthalmologist (Group 1, n=45) and an otorhinolaryngologist (Group 2, n=45) between October 2017 and October 2019. Patients who were admitted with epiphora complaints and diagnosed with primary acquired nasolacrimal duct obstruction through lacrimal irrigation test and aged >18 years with at least 6 months of follow-up were included in the study. In all cases, additional pathologies such as septum deviation were evaluated by performing maxillofacial imaging. Patients' medical records were evaluated in terms of surgery duration, complications, and functional achievements. RESULTS: The mean surgical duration of the patients in Group-2 was 36.27 ± 11.61 min, while it was 43.62 ± 16.89 min in Group-1; the difference was statistically significant (p=0.018). Functional achievements in Group 1 was 84.4% (73.3% in the first set of 15 cases, 93.3% in the last set of 15 cases) in Group 2; this rate was 88.9% (80% in the first set of 15 cases, 93.3% in the last set of 15 cases), and the difference was not statistically significant (p=0.53). Septum intervention in addition to endoscopic surgery in both the groups (p=0.03, p=0.005, respectively) and intense bleeding during surgery (for both the groups, p<0.0001) significantly decreased the functional success. CONCLUSION: Endoscopic endonasal dacryocystorhinostomy, performed after the necessary training, can provide high success and low complication rates when even conducted by ophthalmologists who are unfamiliar with endoscopic surgery after an experience of 30 cases.


Asunto(s)
Dacriocistorrinostomía , Obstrucción del Conducto Lagrimal , Conducto Nasolagrimal , Dacriocistorrinostomía/efectos adversos , Dacriocistorrinostomía/métodos , Humanos , Curva de Aprendizaje , Conducto Nasolagrimal/cirugía , Estudios Retrospectivos , Resultado del Tratamiento
6.
J Craniofac Surg ; 33(2): e105-e107, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-34260448

RESUMEN

PURPOSE: The aim of this study is to determine the demographic characteristics of pediatric open globe injuries, evaluate the ocular trauma scores (OTS), and predict the visual outcomes. METHODS: All patients with pediatric open globe injuries who applied to Department of Ophthalmology, Faculty of Medicine, Mersin University between January 2018 and December 2019 were included in this study. Age, gender, type of injury, time of admission, time to surgery, OTS, and pediatric ocular trauma score (POTS) were calculated for each patient. The relation between these findings and final visual acuity (VA) after 12 months of follow-up was examined. RESULTS: Forty-two eyes of 41 patients were included in this study. The most common injuries observed were sharp objects such as knives (23.8%) and stones (23.8%). The wound locations were zone I in 36 patients (85.7%) and zone II in 6 patients (14.3%). The most common concomitant eye pathologies were iris prolapse in 37 (88.1%) and hyphema in 29 (69.1%). The mean original OTS was 77.21 and the mean POTS was 46.78. Association between OTS/POTS and final VA was very good (Kendall Tau-b = 0.665, P < 0.001, Kendall Tau-b = 0.505, P < 0.001, respectively). The level of agreement between the predicted VA for OTS and that for POTS was almost perfect (kappa = 0.8726). CONCLUSIONS: This study shows that the original OTS is still the gold standard in pediatric cases.


Asunto(s)
Lesiones Oculares Penetrantes , Lesiones Oculares , Niño , Lesiones Oculares/epidemiología , Lesiones Oculares/cirugía , Lesiones Oculares Penetrantes/cirugía , Humanos , Pronóstico , Estudios Retrospectivos , Índices de Gravedad del Trauma , Agudeza Visual
7.
J Craniofac Surg ; 32(7): e679-e680, 2021 Oct 01.
Artículo en Inglés | MEDLINE | ID: mdl-34705373

RESUMEN

ABSTRACT: The aim of this brief clinical study to describe and discuss the subconjunctival fat infiltration encountered in a patient with autologous fat injection. A 50-year-old female patient, who had an autologous fat injection 2 days ago, applied to our clinic with the complaint of redness and burning in the left eye. On anterior segment examination, a raised 20 × 15 mm adipose tissue was observed in the temporal region under the conjunctiva. Infiltrated fat tissue was surgically removed from the subconjunctival area. Subconjunctival fat infiltration is an extremely rare complication after autologous fat injection.


Asunto(s)
Conjuntiva , Órbita , Tejido Adiposo , Femenino , Humanos , Persona de Mediana Edad , Procedimientos Quirúrgicos Oftalmológicos , Trasplante Autólogo
8.
Arq. bras. oftalmol ; 84(3): 279-281, May-June 2021. graf
Artículo en Inglés | LILACS | ID: biblio-1248970

RESUMEN

ABSTRACT The aim of this study was to discuss a case of late-onset Klebsiella oxytoca keratitis after deep anterior lamellar keratoplasty and its treatment. A 21-year-old female patient presented with redness and effluence in the left eye at 5 months after uncomplicated deep anterior lamellar keratoplasty surgery. In the examination, a single suture was loosened in the superior nasal region and there was an infiltration area and epithelial defect in the graft and recipient bed junction in the area of the loose suture. Topical fortified vancomycin and fortified ceftazidime treatment was started empirically hourly, but there was insufficient response. After K. Oxytoca growth in a swab and suture culture taken from the patient, fortified vancomycin was replaced with fortified imipenem. It was observed that the infiltration area rapidly regressed and the epithelial defect was closed after fortified imipenem treatment. Fortified imipenem may be considered as an alternative treatment, especially in cases in which there is no response to treatment and culture growth is detected.(AU)


RESUMO O objetivo deste estudo é discutir um caso de ceratite tardia por Klebsiella oxytoca, após ceratoplastia lamelar anterior profunda, bem como seu tratamento. Uma paciente de 21 anos apresentou vermelhidão e efluxo no olho esquerdo 5 meses após cirurgia de ceratoplastia lamelar anterior profunda sem complicações. Ao exame, havia uma única sutura solta na região nasal superior e uma área de infiltração com defeito epitelial no enxerto e na junção com o leito receptor na área da sutura solta. Iniciou-se empiricamente um tratamento tópico com vancomicina e ceftazidima fortificada de hora em hora, porém com resposta insuficiente. Após o crescimento de K. oxytoca a partir de cultura de swab e sutura retirados da paciente, a vancomicina fortificada foi substituída por imipenem fortificado. Observou-se que a área de infiltração regrediu rapidamente e que o defeito epitelial foi fechado com o tratamento com imipenem fortificado. O imipenem fortificado pode ser considerado um tratamento alternativo, especialmente nos casos sem resposta ao tratamento e detecção de crescimento na cultura.(AU)


Asunto(s)
Humanos , Masculino , Adulto , Imipenem/uso terapéutico , Trasplante de Córnea , Klebsiella oxytoca/aislamiento & purificación , Queratitis/diagnóstico
9.
Arq Bras Oftalmol ; 84(3): 279-281, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-33567032

RESUMEN

The aim of this study was to discuss a case of late-onset Klebsiella oxytoca keratitis after deep anterior lamellar keratoplasty and its treatment. A 21-year-old female patient presented with redness and effluence in the left eye at 5 months after uncomplicated deep anterior lamellar keratoplasty surgery. In the examination, a single suture was loosened in the superior nasal region and there was an infiltration area and epithelial defect in the graft and recipient bed junction in the area of the loose suture. Topical fortified vancomycin and fortified ceftazidime treatment was started empirically hourly, but there was insufficient response. After K. Oxytoca growth in a swab and suture culture taken from the patient, fortified vancomycin was replaced with fortified imipenem. It was observed that the infiltration area rapidly regressed and the epithelial defect was closed after fortified imipenem treatment. Fortified imipenem may be considered as an alternative treatment, especially in cases in which there is no response to treatment and culture growth is detected.


Asunto(s)
Trasplante de Córnea , Queratitis , Adulto , Femenino , Humanos , Imipenem , Klebsiella oxytoca , Suturas , Adulto Joven
10.
J Ocul Pharmacol Ther ; 37(4): 200-208, 2021 05.
Artículo en Inglés | MEDLINE | ID: mdl-33481657

RESUMEN

Purpose: The aim of this study was to investigate the microRNA (miRNA) expressions of the corneal tissue after an alkaline burn and to compare the efficiency of adipose- and bone marrow-derived mesenchymal stem cells (MSCs) on expressions. Methods: Thirty-two rats were divided into 4 groups. No intervention was made in the control group. A chemical burn was created by applying 4 µL NaOH soaked in 6 mm filter paper to the right eye of each animal in the other groups. Whereas only subconjunctival 0.1 mL phosphate-buffered saline (PBS) was injected to in the group 1, 2 × 106 adipose- or bone marrow-derived MSC in 0.1 mL PBS was injected subconjunctivally to the animals in the remaining groups (groups 2 and 3, respectively). Tissue samples were collected for miRNA analysis on the third day after the burn. Results: When group 1 was compared with the control group, the expression of 3 of 93 miRNAs increased significantly, whereas the expression of 50 miRNAs decreased significantly. Significant changes in miRNA expressions were observed when group 1 was compared with groups 2 and 3. Although a significant change was observed in the expression of 6 miRNAs in the adipose-derived MSC group, it was found that the expression of 65 miRNAs significantly changed in the bone marrow-derived MSC group. Conclusion: This study shows that there are significant changes in some miRNA expressions after corneal alkaline burn and these changes can be reversed with the subconjunctival injection of MSCs.


Asunto(s)
Quemaduras/metabolismo , Trasplante de Células Madre Mesenquimatosas/efectos adversos , Células Madre Mesenquimatosas/metabolismo , MicroARNs/genética , Animales , Células de la Médula Ósea/metabolismo , Quemaduras/terapia , Estudios de Casos y Controles , Células Cultivadas/trasplante , Córnea/metabolismo , Lesiones de la Cornea/inducido químicamente , Lesiones de la Cornea/patología , Modelos Animales de Enfermedad , Masculino , Microscopía Fluorescente/métodos , Ratas , Ratas Sprague-Dawley
11.
J Ocul Pharmacol Ther ; 37(1): 24-34, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-33275515

RESUMEN

Purpose: The aim of the present study is to comparatively evaluate the anti-inflammatory and antiapoptotic effects of bone marrow and adipose-derived mesenchymal stem cells (MSCs) applied subconjunctivally after alkaline corneal burn. Methods: Thirty-two rats were divided into 4 groups and included in the study (n = 8). While no intervention was made in the control group, a chemical burn was created by applying 4 µL of NaOH soaked in 6 mm filter paper to the right eye of each subject in the other groups under general anesthesia. While only subconjunctival 0.1 mL phosphate-buffered saline (PBS) was injected to in the group 1, 2 × 106 adipose or bone marrow-derived MSC in 0.1 mL PBS was applied subconjunctivally to the subjects in the remaining groups (Group 2 and 3, respectively). Tissue samples were collected for histological analysis on the third day after the burn. Tissue samples were evaluated light microscopically and immunohistochemically stained for interleukin-1 beta (IL-1ß), tumor necrosis factor alpha (TNF-α), caspase-3 (Cas-3), and CD68. Results: The IL-1ß and TNF-α staining scores and the number of CD68- and Cas-3-positive stained cells were significantly lower in the groups given bone marrow and adipose-derived MSC compared to the alkaline burn group (P < 0.0001, for all parameters). Epithelial IL-1ß and TNF-α staining scores were significantly lower in the bone marrow-derived MSC group compared to the adipose-derived MSC group (P < 0.0001, for all parameters). Conclusions: The presented study shows that both bone-marrow and adipose-derived MSCs support wound healing in the corneal tissue and strongly suppress the inflammation occured in the tissue.


Asunto(s)
Antiinflamatorios/metabolismo , Médula Ósea/metabolismo , Córnea/metabolismo , Lesiones de la Cornea/metabolismo , Células Madre Mesenquimatosas/metabolismo , Animales , Apoptosis , Córnea/efectos de los fármacos , Córnea/patología , Lesiones de la Cornea/patología , Masculino , Ratas , Ratas Sprague-Dawley , Hidróxido de Sodio/farmacología
12.
Turk J Ophthalmol ; 50(1): 1-5, 2020 03 05.
Artículo en Inglés | MEDLINE | ID: mdl-32166941

RESUMEN

Objectives: To investigate the relationship between optical coherence tomography (OCT) signal strength (SS) and visual acuity in patients with posterior capsule opacification (PCO) and evaluate the effect of PCO on retinal thickness measurements. Materials and Methods: Forty-one eyes of 35 patients who were diagnosed with PCO were included in the study. Patients with any anterior or posterior segment pathology other than PCO were excluded. After ophthalmologic examination, pupil dilation was induced using 0.5% tropicamide and OCT images were acquired. The assessment was repeated 1 month after Nd:YAG laser capsulotomy and postoperative values were compared with baseline values. Results: The patients' mean best corrected visual acuity (BCVA) was 0.28±0.13 preoperatively and 0.78±0.09 postoperatively (p<0.0001). Strong positive correlations were observed between BCVA and SS both pre- and postoperatively (p<0.0001 and p=0.01, respectively). Central retinal thickness (CRT) and SS increased significantly postoperatively (p<0.0001 for both). OCT SS and CRT were strongly correlated preoperatively (p=0.001) but not postoperatively (p=0.46). Conclusion: OCT SS correlates with visual acuity in patients with PCO, and PCO can affect the accuracy of objective data obtained with OCT.


Asunto(s)
Opacificación Capsular/diagnóstico , Terapia por Láser/métodos , Láseres de Estado Sólido/uso terapéutico , Tomografía de Coherencia Óptica/métodos , Agudeza Visual , Opacificación Capsular/cirugía , Femenino , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , Estudios Retrospectivos
13.
J Pediatr Hematol Oncol ; 42(2): 92-99, 2020 03.
Artículo en Inglés | MEDLINE | ID: mdl-31851069

RESUMEN

OBJECTIVE: The aim of this study was to compare optical coherence tomography (OCT) findings in pediatric patients with sickle cell disease (SCD) and healthy individuals and to investigate associations between these data and the patients' systemic findings. MATERIALS AND METHODS: The study included 108 eyes of 54 patients with SCD with no visual symptoms and a control group consisting of 110 eyes of 55 healthy subjects with no systemic or ocular pathology. After best-corrected visual acuity assessment, the study participants underwent a complete ophthalmologic examination including intraocular pressure. After examination and pupil dilation induced with 1% tropicamide, 9×9 mm macular sections were obtained with spectral-domain OCT. The macular sections were evaluated according to Early Treatment Diabetic Retinopathy Study (ETDRS) map and internal and external retinal thicknesses were measured using the software included in the OCT device. RESULTS: The patient group showed significantly more foveal flattening, temporal thinning, and vascular tortuosity than the control group (P<0.0001 for all). Foveal width was significantly greater in the patient group (1592.39±175.56 µm) compared with the control group (1391.01±175.56 µm) (P<0.0001), whereas foveal depth was significantly lower in the patient group (121.15±26.83 µm) than in the control group (146.1±12.25 µm) (P<0.0001). The mean total retinal thickness was 253.53±22.31 µm in the patient group and 261.03±18.48 µm in the control group (P=0.007). Similarly, central retinal thickness was significantly lower in the patient group (219.35±10.53 µm) compared with the control group (235.32±12.51 µm) (P<0.0001). DISCUSSION: Our study shows that pediatric patients with SCD may have subclinical retinal involvement and that temporal thinning, in particular, is an important OCT finding. This strongly suggests that OCT imaging would be a beneficial addition to routine ophthalmologic examination in the diagnosis and follow-up of this patient group.


Asunto(s)
Anemia de Células Falciformes/complicaciones , Enfermedades de la Retina/diagnóstico , Tomografía de Coherencia Óptica/métodos , Adolescente , Anemia de Células Falciformes/diagnóstico por imagen , Anemia de Células Falciformes/patología , Estudios de Casos y Controles , Niño , Femenino , Estudios de Seguimiento , Humanos , Masculino , Ensayos Clínicos Controlados no Aleatorios como Asunto , Pronóstico , Estudios Prospectivos , Enfermedades de la Retina/diagnóstico por imagen , Enfermedades de la Retina/etiología
14.
Arq. bras. oftalmol ; 82(3): 239-241, May-June 2019. graf
Artículo en Inglés | LILACS | ID: biblio-1001313

RESUMEN

ABSTRACT Fibroepithelial polyps are benign non-epithelial tumors arising from mesodermal tissue and are commonly found on the skin. They can develop on the eyelid and surrounding area and rarely appear at other sites. While most cutaneous cases are diagnosed incidentally, the lesions may be symptomatic based on their location. The etiology of fibroepithelial polyps is not fully understood but may involve trauma, chronic irritation, allergic factors, and developmental or congenital causes. Although fibroepithelial polyps are benign lesions, they can be malignant in extremely rare cases. Herein we discuss 2 cases of fibroepithelial polyp with an atypical presentation and their treatment.


RESUMO Pólipos fibroepiteliais são tumores benignos não-epiteliais que surgem do tecido mesodérmico e são comumente encontrados na pele. Eles podem se desenvolver na pálpebra e na área adjacente, e raramente aparecem em outros locais. Embora a maioria dos casos cutâneos seja diagnosticada incidentalmente, as lesões podem ser sintomáticas com base em sua localização. A etiologia dos pólipos fibroepiteliais não é completamente compreendida, mas pode envolver trauma, irritação crônica, fatores alérgicos e causas de desenvolvimento ou congênitas. Apesar dos pólipos fibroepiteliais serem lesões benignas, podem ser malignos em casos extremamente raros. Aqui discutimos 2 casos de pólipo fibroepitelial com uma apresentação atípica e seu tratamento.


Asunto(s)
Humanos , Masculino , Preescolar , Persona de Mediana Edad , Pólipos/patología , Pólipos/terapia , Neoplasias Fibroepiteliales/patología , Neoplasias de la Conjuntiva/psicología , Neoplasias de los Párpados/patología , Neoplasias Fibroepiteliales/terapia , Neoplasias de la Conjuntiva/terapia , Neoplasias de los Párpados/terapia
15.
Arq Bras Oftalmol ; 82(3): 239-241, 2019.
Artículo en Inglés | MEDLINE | ID: mdl-30916216

RESUMEN

Fibroepithelial polyps are benign non-epithelial tumors arising from mesodermal tissue and are commonly found on the skin. They can develop on the eyelid and surrounding area and rarely appear at other sites. While most cutaneous cases are diagnosed incidentally, the lesions may be symptomatic based on their location. The etiology of fibroepithelial polyps is not fully understood but may involve trauma, chronic irritation, allergic factors, and developmental or congenital causes. Although fibroepithelial polyps are benign lesions, they can be malignant in extremely rare cases. Herein we discuss 2 cases of fibroepithelial polyp with an atypical presentation and their treatment.


Asunto(s)
Neoplasias de la Conjuntiva/patología , Neoplasias de los Párpados/patología , Neoplasias Fibroepiteliales/patología , Pólipos/patología , Preescolar , Neoplasias de la Conjuntiva/terapia , Neoplasias de los Párpados/terapia , Humanos , Masculino , Persona de Mediana Edad , Neoplasias Fibroepiteliales/terapia , Pólipos/terapia
16.
Int Ophthalmol ; 38(4): 1703-1708, 2018 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-28695379

RESUMEN

PURPOSE: In the present study, we aimed to evaluate the expression of EP receptors in primary and recurrent human pterygium tissues. METHODS: Pterygium samples were collected from 65 patients with primary pterygium and 16 patients with recurrent pterygium. Normal conjunctival tissues were collected from nasal interpalpebral area from 17 patients without systemic and any other ocular pathology. Expression of EP receptors was evaluated by immunohistochemistry. The median value for each receptor staining score (RSS) was determined in normal conjunctival specimens. In this study, RSS of > median value was defined as positive staining or high expression and ≤ median value as negative staining or weak expression in specimens. Chi-square test was used for statistical analysis, and p value of less than 0.05 was considered significant. RESULTS: Stromal expression of EP1 was significantly higher in primary and recurrent pterygium specimens compared to normal conjunctival tissues (p = 0.007 and p = 0.002, respectively). Epithelial expressions of EP2 and EP3 were significantly lower in primary pterygium specimens compared to normal conjunctival tissues (p = 0.005 and p < 0.0001, respectively), and stromal expressions were insignificant. Stromal expression of EP4 was significantly higher in primary and recurrent pterygium specimens compared to normal conjunctival tissues (p = 0.002 and p = 0.012, respectively). CONCLUSIONS: Expression of EP receptors has been up- or downregulated in primary and recurrent pterygium tissues, and these receptors may play a role in formation and recurrence of pterygium.


Asunto(s)
Conjuntiva/metabolismo , Pterigion/metabolismo , Receptores de Prostaglandina E/metabolismo , Adulto , Estudios de Casos y Controles , Sustancia Propia/metabolismo , Femenino , Humanos , Inmunohistoquímica , Masculino , Persona de Mediana Edad
17.
Turk Neurosurg ; 28(2): 282-287, 2018.
Artículo en Inglés | MEDLINE | ID: mdl-28127724

RESUMEN

AIM: Conservative treatment is a frequently used treatment modality for traumatic thoracolumbar fractures. However, not many studies evaluating radiological and clinical results of conservative treatment are found. The aim of this study was to determine the risk factors, and compression and kyphosis rates after 1 year in patients with AO type A thoracic, thoracolumbar, and lumbar fractures treated conservatively. MATERIAL AND METHODS: Radiological and clinical results of 79 thoracolumbar fractures in 57 patients, who were treated conservatively, were evaluated one year after trauma. Fractures were classified according to thoracolumbar injury classification and severity (TLICS) score and AO spinal trauma classification system. Compression rate, wedge and kyphosis angles, and sagittal index were calculated in early and late periods after trauma. RESULTS: Female/male ratio was 25/32, and mean age was 41.7±16.7 years. They were followed for 15.2±4.9 months. Mean compression rates were 19.6% and 25.2%; wedge angles were 10.1 and 12.7 degrees; kyphosis angles were 5.82 and 8.9 degrees; and sagittal indexes were 8.01 and 10.13 in all patients just after trauma and after one year, respectively. Fractures in older patients ( > 60 years of age) and in patients with osteopenia or osteoporosis, located in the thoracolumbar junction, AO type A2 and A3 fractures, and solitary fractures had higher compression and kyphosis rates at last follow-up. CONCLUSION: Early mobilization without bed rest for stable thoracolumbar fractures according to the TLICS system is a good treatment option, and radiological and clinical results are usually acceptable. However, fractures in patients older than 60 years, those with osteoporosis or osteopenia, fractures located in the thoracolumbar junction, solitary fractures, and fractures in AO type A2 or A3, are more inclined to increase in compression and kyphosis and may require a closer follow-up.


Asunto(s)
Tratamiento Conservador/métodos , Fracturas de la Columna Vertebral/complicaciones , Fracturas de la Columna Vertebral/patología , Fracturas de la Columna Vertebral/terapia , Adulto , Anciano , Femenino , Humanos , Puntaje de Gravedad del Traumatismo , Cifosis/epidemiología , Cifosis/etiología , Vértebras Lumbares/lesiones , Masculino , Persona de Mediana Edad , Factores de Riesgo , Vértebras Torácicas/lesiones
18.
Int Ophthalmol ; 38(6): 2357-2361, 2018 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-29027061

RESUMEN

PURPOSE: To evaluate visual outcomes and complications in scleral fixated intraocular lens (IOL) implantation with the modified Z-suture technique. MATERIALS AND METHODS: Thirty-five eyes of 35 patients (20 male, 15 female) were included in the study. Patients underwent scleral fixated IOL implantation using the modified Z-suture technique and were followed in terms of visual acuity and complications. RESULTS: Mean postoperative follow-up time was 12.46 ± 7.46 months. Mean best corrected visual acuity was 1.35 ± 0.91 logMAR preoperatively and 0.48 ± 0.39 logMAR postoperatively, and difference was statistically significant (p < 0.001). No suture-related complications were observed during follow-up in any of the patients. Slight infero-temporal dislocation of the IOL was observed at postoperative 5 months in one patient (2.85%) who experienced blunt trauma. It caused no optical disturbance, and repeated surgery was not advised. Transient intravitreal hemorrhage was observed in two patients (5.7%) who underwent combined scleral fixation and pupilloplasty. DISCUSSION: The modified Z-suture technique is simple, fast, and was determined to be safe in terms of complications. However, long-term outcomes should be evaluated in larger patient groups.


Asunto(s)
Implantación de Lentes Intraoculares/métodos , Facoemulsificación , Esclerótica/cirugía , Técnicas de Sutura , Anciano , Femenino , Estudios de Seguimiento , Humanos , Lentes Intraoculares , Masculino , Persona de Mediana Edad , Seudofaquia/fisiopatología , Agudeza Visual/fisiología
19.
Turk Neurosurg ; 2017 Jul 16.
Artículo en Inglés | MEDLINE | ID: mdl-28944948

RESUMEN

AIM: Laminar screw technique is used to stabilize C2 and other levels when other techniques cannot be performed. MATERIAL AND METHODS: The patients underwent laminar screws at cervical and upper thoracic levels in our clinic during 5 yearswere evaluated retrospectively. RESULTS: In 25 patients, 6 to 82 years old,total 54 laminar screws were used. Most frequent diagnoses were cervical spinal stenosis and craniovertebraljunction anomalies.There were handicaps to perform other type of screwsin 19 out of 25 screws during first 4 years, and 9 out of 29 in the last year (p=0.0009).Two modifications were performed in some cases. In 4 segments with thin lamina, a shorter screw was performed to leave clear the thinnest part, and in 3 C2 levels with almost full length bifid spinous process,shorter screws were inserted from medial sides of the bifid processes with a more vertical orientation. There was ventral cortex penetration in 11 screws without new neurological deficits. One of them was removed because of its full thickness insertion into the spinal canal.Fusion rate was 75% in 16 patients followed radiologically longer than 6 months.In one patient out of 4 without fusion, unilateral screw was loosened, and in others laminar screws were not loosened. CONCLUSION: Laminar screw technique is easy, safe and effective at C2, C7 and upper thoracic levels. Some modifications may be required due to the anatomical variations.It can be used at other subaxial levels also in theselected cases that other techniques could not be performed.

20.
J Craniofac Surg ; 28(8): e752-e756, 2017 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-28953146

RESUMEN

PURPOSE: In this study, the authors aimed to identify facial and nasal parameters, which may create an anatomic disposition toward obstruction in patients with primary acquired nasolacrimal duct obstruction. MATERIALS AND METHODS: Forty-eight patients (14 males and 34 females) who presented to the ophthalmology outpatient clinic and were diagnosed with primary acquired nasolacrimal duct obstruction between January 2014 and January 2015 were included in the study. The control group comprised 59 patients (38 females and 21 males) without nasolacrimal duct obstruction. Measurements of nasal height, length, and depth, presence of a nasal hump, alar width and alar angle, distance between the maxillary bone nasal notches, and right and left distances between outer canthi and corners of the mouth were made using photographs of the patients. The presence of facial asymmetry was also assessed. RESULTS: Facial asymmetry (P = 0.014) and nasal hump (P = 0.048) were more common in the patient group. The patient group had smaller nasal radix depth (P < 0.001), nasal length (P = 0.001), and alar width (P < 0.001), larger distance between maxillary bone nasal notches (P < 0.001), and smaller alar angle (P < 0.001). CONCLUSION: In the current study, the authors found that primary acquired nasolacrimal duct obstruction occurred more frequently on the side of the face with shorter facial measurements. Smaller nasal radix depth, nasal length, and alar base width, presence of a nasal hump and longer distance between maxillary bone nasal notches may form an anatomic basis for nasolacrimal duct obstruction. Based on our results, the authors believe that primary acquired nasolacrimal duct obstruction is associated with facial structure.


Asunto(s)
Asimetría Facial/epidemiología , Obstrucción del Conducto Lagrimal/epidemiología , Conducto Nasolagrimal , Nariz/anatomía & histología , Adulto , Anciano , Estudios de Casos y Controles , Femenino , Humanos , Obstrucción del Conducto Lagrimal/diagnóstico , Masculino , Persona de Mediana Edad , Boca/anatomía & histología
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