Systematic reviews on the success of dental implants present low spin of information but may be better reported and interpreted: An overview of systematic reviews with meta-analysis.

OBJECTIVE: To estimate the prevalence of spin and completeness of reporting of systematic reviews with metanalysis (SRMAs) in implant dentistry. STUDY DESIGN AND SETTING: Inclusion criteria were SRMAs of randomized clinical trials of implant dentistry on survival, success, or failure rates in humans, with no language restriction. Three databases were searched from inception to May 2021. Main outcomes were prevalence of spin (primary outcome) and completeness of reporting (secondary outcome) in abstracts and full texts. RESULTS: We identified 2481 SRMAs and 45 unique manuscripts were included. There was a low presence of spin in the abstracts and full text, except for adverse events, in which 51.1% (in the abstract) failed to mention any adverse event for summarized interventions. There was an adequate report of SRMAs in the full text except for prospective register (33.3% not reported). However, there was an incomplete report for most items in the abstract considering PRISMA-A checklist. CONCLUSION: In general, the included SRMAs presented a (a) low prevalence of spin (except for adverse events in the abstract); (b) adequate completeness of reporting in the full text (except for prospective register); and (c) incomplete report for most items in the abstracts.

Influence of post type on periapical status: a prospective study in a Brazilian population.

OBJECTIVES: This prospective study assessed the effect of post type used to restore endodontically treated teeth in the onset, progression, and remission of periapical lesions. MATERIALS AND METHODS: One hundred and forty teeth (92 patients) were endodontically treated and received a glass fiber post or a cast metal post and a final restoration at a University Clinic by undergraduate students. All patients were followed up for a mean period of 5.1 ± 2.2 years. Periapical Index (PAI) was used for endodontic assessment. Two calibrated and blind examiners assessed the radiographs. The longevity of the endodontic treatment was analyzed using Kaplan-Meier statistics. RESULTS: Of the included teeth, 67.1% received glass fiber posts while 32.9% received cast metal posts. There were 4 endodontic failures, two glass fiber posts with a PAI = 3 in the baseline and PAI = 4 in the last follow-up, and one PAI = 4 in baseline and last follow-up. One cast metal post-failure was PAI = 4 in the baseline and the last follow-up. After 9.4 years, the overall success rate of the endodontic treatment was 97.1% (p = 0.7). CONCLUSIONS: The tested posts presented similar endodontic healing. Precautions taken during endodontic therapy, post cementation, and final restoration are more likely to be responsible for the success of endodontic treatment rather than a specific type of post. Clinical relevance The type of post is not related to the success of the endodontic treatment.

Short vs standard implants associated with sinus floor elevation: a randomized controlled trial / Implantes curtos versus implantes convencionais associados à elevação do seixo maxilar: um ensaio clínico randomizado

Objective: the present equivalence two-arm parallel randomized controlled trial aimed to compare survival and marginal bone loss (MBL) of short implants (≤6 mm) and standard implants (≥8.5 mm) associated with sinus floor elevation (SFE). Methods: adult patients with partial edentulism with occlusal stability in the sinus area and intermediate bone height were selected in this double-blind trial (patient and outcome assessment). Patients were randomly allocated into two groups: standard length implants with SFE (control) or short implants (test). Clinical and radiographic assessments were made at the time of implant placement, 6 months, and annually thereafter up to 2 years after loading. The inter-examiner agreement was analyzed using intraclass correlation coefficient (ICC). One-way ANOVA, Kaplan-Meier, and Log-rank tests were used to compare implant survival (primary outcome) and MBL (secondary outcome) (P<0.05). Results: eight short implants and six standard implants were placed (mean age of patients was 47 ±12.5 years). The implant survival rates were 87.5% for short (one 5 mm implant failed at 7 months) and 100% for standard implants with no statistically significant difference between groups (P=0.4). The mean MBL after 1 year was 0.30 ±0.62 mm for short and 0.21 ±0.36 mm for standard implants (P=0.123). The inter-examiner agreement was set in 0.831. Conclusion: survival of short implants and standard implants associated with SFE was similar after two years of clinical service. Trial registration: Registered on 27-03-2018 at ClinicalTrials.gov (NCT03479333). Funding: This study was partially funded by Capes Finance Code 001 and #88881.187933/2018-01. TPC is partially funded by National Council for Scientific and Technological Development (CNPq - Brazil). The funders had no role in the study design, data collection and analysis, decision to publish or preparation of the manuscript.(AU)

Objetivo: o presente ensaio clínico randomizado de dois braços de equivalência comparou a taxa de sobrevivência e a perda óssea marginal de implantes curtos (≤ 6 mm) e implantes convencionais (≥ 8.5 mm) associados à elevação do seio maxilar. Métodos: edêntulos parciais adultos, com estabilidade oclusal e altura óssea intermediária na região do seio maxilar, foram selecionados neste estudo duplo-cego e alocados randomicamente em dois grupos: implante de comprimento convencional associado à elevação do seio maxilar (controle) ou implante curto (teste). Avaliações clínicas e radiográficas foram realizadas logo após a instalação do implante, seis meses e anualmente por até dois anos. A concordância interexaminador foi avaliada através do coeficiente de correlação intraclasse. Os testes ANOVA de uma via, Kaplan-Meier e Log-rank foram utilizados para comparar a sobrevivência do implante e a perda óssea marginal (P<0.05). Resultados: oito implantes curtos e seis implantes de comprimento convencional foram instalados em onze pacientes (média de idade dos pacientes: 47 ± 12.5 anos). As taxas de sobrevivência dos implantes foram de 87,5% para implantes curtos (um implante de 5 mm falhou aos sete meses), e 100% para implantes convencionais, sem diferença estatisticamente significativa entre os grupos (P=0.4). A perda óssea marginal média após um ano foi de 0.30 ±0.62 mm para implantes curtos e 0.21 ±0.36 mm para implantes convencionais (P=0.123). A concordância interexaminador foi de 0.831. Conclusão: a taxa de sobrevivência de implantes curtos e convencionais associados ao seio maxilar foi semelhante após dois anos de acompanhamento. Registro do estudo: Registrado em 27-03-2018 no ClinicalTrials.gov (NCT03479333).(AU)

Laser terapêutico e células inflamatórias - parte 1: mastócitos* / Therapeutic laser and inflammatory cells - part 1: mast cells

O presente estudo avaliou a quantidade de mastócitos após irradiação do laser não cirúrgico λ685 nm. Dezoito ratos machos, linhagem Wistar (250 a 300 gramas), nos quais foram realizadas feridas cirúrgicas padronizadas, foram distribuídos em seis grupos, três experimentais (com quatro ratos) e três controles (com dois ratos). Os grupos experimentais foram irradiados em quatro pontos perilesionais equidistantes (0,5 J/cm², 35 mW, 35 Hz e 17 segundos). Os grupos-controles não foram irradiados. Os animais foram mortos 6, 12 e 24 horas após a irradiação, sendo obtidas peças que seguiram para processamento laboratorial de rotina. O estudo das lâminas foi realizado por meio da contagem absoluta dos mastócitos pelo método esteriológico. Os resultados obtidos demonstraram que, nas primeiras 6 e 12 horas, após a irradiação laser, existe uma diminuição no número total de mastócitos, estatisticamente significante, quando comparados aos grupos controles, porém, após 24 horas, não existem diferenças no número de mastócitos entre os grupos experimental e controle. Baseados nos resultados obtidos com o protocolo de aplicação da luz laser utilizado, para esse modelo animal, pôde-se concluir que a luz laser é capaz de diminuir o número total de mastócitos após uma única irradiação.

This study measured the variation in the total number of mast cells after low level laser therapy (λ= 685 nm) using a stereological method. Eighteen male Wistar rats (250 to 300 grams) with standardized surgical wounds were randomly distributed into 6 groups - 3 study groups with 4 rats each, and 3 control groups with 2 rats each. In the study groups, four equidistant spots around the standardized wound were irradiated (0.5 J/cm², 35 mW, 35 Hz, 17 seconds). The control groups were not irradiated. The animals were killed at 6, 12 and 24 hours after laser therapy. Biological specimens were harvested and routinely processed; slides were prepared and stained with toluidine blue. The total number of mast cells was counted using the stereological method. A statistically significant decrease in the total number of mast cells was observed at 6 and 12 hours after irradiation. However, there was nodifference in the number of mast cells between study and control groups at 24 hours. Our results showed that one single irradiation with laser light reduced the total number of mast cells in the animal model used in this study.

Laser terapêutico e células inflamatórias - parte 2: neutrófilos* / Therapeutic laser and inflammatory cells - part 2: neutrophils

O objetivo deste trabalho foi estudar a intensidade do infiltrado inflamatório agudo, presente em tecido conjuntivo perilesional do dorso de ratos submetidos à irradiação laser de baixa potência (λ 685 nm) após uma única aplicação. Foram utilizados dezoito ratos machos, linhagem Wistar, de 250 a 300 gramas, nos quais foram realizadas feridas cirúrgicas padronizadas. A amostra foi constituída de seis grupos, três experimentais e três controles, compostos por quatro e dois ratos, cada grupo, respectivamente. Os grupos experimentais foram irradiados em quatro pontos perilesionais equidistantes, com uma única dose de 0,5J/cm² por ponto, com potência de 35 mW, frequência de 35 pulsos por segundo e tempo de aplicação por ponto de 17 s. Os grupos-controles não foram irradiados. Os animais foram mortos 6, 12 e 24 horas após a irradiação, sendo obtidas peças que seguiram para processamento laboratorial de rotina. O estudo das lâminas foi realizado através da descrição e contagem absoluta dos granulócitos pelo método esteriológico. Os resultados obtidos demonstraram que há uma diminuição no número total de granulócitos, não significante estatisticamente (p≥0,05), quando comparados aos grupos controles. Concluiu-se que a luz laser é capaz de diminuir a intensidade do infiltrado inflamatório após uma única irradiação.

The aim of this work was study the intensity of acute inflammatory infiltrate inconnective tissue after low level laser therapy (λ = 685 nm) irradiation. Eighteen maleWistar rats (250 to 300 grams) with standardized surgical wounds were randomlydistributed into 6 groups - 3 study groups with 4 rats each, and 3 control groups with2 rats each. In the study groups, four equidistant spots around the standardizedwound were irradiated (0.5 J/ cm², 35 mW, 35 Hz, 17 seconds). The control groupswere not irradiated. The animals were killed at 6, 12 and 24 hours after laser therapy.Biological specimens were harvested and routinely processed. The total number of granulocyteswascounted using the stereological method. A non-statistically significant decrease in thetotal number granulocytes was observed in the all study groups. Our results showedthat one single irradiation with laser light reduced the total number of graunulocytesin the animal model used in this study.