Update on the management of elderly patients with colorectal cancer

Colorectal cancer (CRC) is one of the most common tumours worldwide, and 70% of CRC patients are over 65 years of age. However, the scientific evidence available for these patients is poor, as they are underrepresented in clinical trials. Therefore, a group of experts from the Oncogeriatrics Section of the Spanish Society of Medical Oncology (SEOM), the Spanish Cooperative Group for the Treatment of Digestive Tumours, (TTD) and the Multidisciplinary Spanish Group of Digestive Cancer (GEMCAD) have reviewed the scientific evidence available in older patients with CRC. This group of experts recommends a multidisciplinary approach and geriatric assessment (GA) before making a therapeutic decision because GA predicts the risk of toxicity and survival and helps to individualize treatment. In addition, elderly patients with localized CRC should undergo standard cancer resection, preferably laparoscopically. The indication for adjuvant chemotherapy (CT) should be considered based on the potential benefit, the risk of recurrence, the life expectancy and patient comorbidities. When the disease is metastatic, the possibility of radical treatment with surgery, radiofrequency (RF) or stereotactic body radiation therapy (SBRT) should be considered. The efficacy of palliative CT is similar to that seen in younger patients, but elderly patients are at increased risk of toxicity. Clinical trials should be conducted with the elderly population and include GAs and specific treatment plans (AU)

Update on the management of elderly patients with colorectal cancer.

Colorectal cancer (CRC) is one of the most common tumours worldwide, and 70% of CRC patients are over 65 years of age. However, the scientific evidence available for these patients is poor, as they are underrepresented in clinical trials. Therefore, a group of experts from the Oncogeriatrics Section of the Spanish Society of Medical Oncology (SEOM), the Spanish Cooperative Group for the Treatment of Digestive Tumours, (TTD) and the Multidisciplinary Spanish Group of Digestive Cancer (GEMCAD) have reviewed the scientific evidence available in older patients with CRC. This group of experts recommends a multidisciplinary approach and geriatric assessment (GA) before making a therapeutic decision because GA predicts the risk of toxicity and survival and helps to individualize treatment. In addition, elderly patients with localized CRC should undergo standard cancer resection, preferably laparoscopically. The indication for adjuvant chemotherapy (CT) should be considered based on the potential benefit, the risk of recurrence, the life expectancy and patient comorbidities. When the disease is metastatic, the possibility of radical treatment with surgery, radiofrequency (RF) or stereotactic body radiation therapy (SBRT) should be considered. The efficacy of palliative CT is similar to that seen in younger patients, but elderly patients are at increased risk of toxicity. Clinical trials should be conducted with the elderly population and include GAs and specific treatment plans.

Vómitos / Vomiting

Los vómitos son un motivo frecuente de consulta. La mayoría de las veces se deben a enfermedades benignas; sin embargo, pueden ser el síntoma inicial de patologías graves y complejas, como procesos neoplásicos con afectación del sistema nervioso central, donde son el resultado del aumento de la presión intracraneal. El cáncer de testículo representa aproximadamente el 1 % de todas las neoplasias y constituye la neoplasia maligna más frecuente en hombres de entre 15 y 34 años. El coriocarcinoma supone entre el 0,3 y el 1 % de las neoplasias testiculares; es considerado como el más raro y con peor pronóstico de todas debido a su rápida diseminación. La mayoría de los casos debutan con síntomas en relación con las metástasis. Presentamos el caso de un paciente de 16 años que acude a consulta por mareos y vómitos. Presentaba una auscultación pulmonar patológica, por la que se solicitó una radiografía torácica que mostró neumotórax derecho e imagen en suelta de globos. Al ampliar estudio, se objetiva una B-HCG elevada y lesión nodular en la ecografía testicular. En el TAC cerebral se objetivaron lesiones metastásicas responsable de los vómitos. Se realizó biopsia de una lesión ulcerada del cuero cabelludo que informó metástasis de coriocarcinoma testicular

Vomiting is a frequent complaint. Most times it is caused by benign conditions. However, it can also be the initial symptom of serious and complex illnesses, such as neoplastic processes with central nervous system involvement, where vomiting is the result of increased intracranial pressure. Testicular cancer accounts for 1% of all neoplasms, and is the most frequent malignancy in men between 15 and 34 years. Choriocarcinoma accounts for 0.3-1% of testicular neoplasms, and it is considered the rarest of all and the one with the worst prognosis due to rapid spread. Most cases begin with symptoms related to the metastases. We present the case of a 16-year-old patient with dizziness and vomiting. His pulmonary auscultation was pathological, so a chest x-ray was performed, showing right pneumothorax and multiple pulmonary nodules. Further study showed elevated B-HCG and a nodular lesion in testicular ultrasound. Metastatic lesions responsible for the vomiting were found in the brain CT. A biopsy of an ulcerated lesion of the scalp showed metastasis of testicular choriocarcinoma

¿Existen diferencias en la derivación de las pacientes con cáncer de mama según se realice desde cirugía general o ginecología? / Collapse therapy of pulmonary tuberculosis

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Encuesta sobre las medidas de prevención antitabáquica en la red de hospitales del Insalud / A survey about the measures of smoking control in the network of Insalud hospitals

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