RESUMEN
Brazilian spotted fever is an acute febrile infectious disease caused by Rickettsia rickettsii, transmitted by tick bite. As this disease is rare and has high mortality rates in Brazil, the clinical aspects and epidemiological data may help the diagnosis. We report a case of Brazilian spotted fever in a 19-year-old patient who presented maculopapular exanthema in the palmar region and upper limbs, lymphadenopathy, fever, chills, headache, conjunctival hyperemia, nausea, vomiting, dyspnea, myalgia, developing neurological signs and abdominal pain. He was treated with doxycycline with clinical improvement. We emphasize the importance of the recognition of this disease by dermatologists as cutaneous manifestations are the key findings to establish early diagnosis and prevent complications.
Asunto(s)
Fiebre Maculosa de las Montañas Rocosas/patología , Enfermedades Cutáneas Bacterianas/patología , Antibacterianos/uso terapéutico , Brasil , Doxiciclina/uso terapéutico , Diagnóstico Precoz , Humanos , Masculino , Rickettsia rickettsii , Fiebre Maculosa de las Montañas Rocosas/tratamiento farmacológico , Piel/patología , Enfermedades Cutáneas Bacterianas/tratamiento farmacológico , Adulto JovenRESUMEN
Brazilian spotted fever is an acute febrile infectious disease caused by Rickettsia rickettsii, transmitted by tick bite. As this disease is rare and has high mortality rates in Brazil, the clinical aspects and epidemiological data may help the diagnosis. We report a case of Brazilian spotted fever in a 19-year-old patient who presented maculopapular exanthema in the palmar region and upper limbs, lymphadenopathy, fever, chills, headache, conjunctival hyperemia, nausea, vomiting, dyspnea, myalgia, developing neurological signs and abdominal pain. He was treated with doxycycline with clinical improvement. We emphasize the importance of the recognition of this disease by dermatologists as cutaneous manifestations are the key findings to establish early diagnosis and prevent complications.
Asunto(s)
Humanos , Masculino , Adulto Joven , Fiebre Maculosa de las Montañas Rocosas/patología , Enfermedades Cutáneas Bacterianas/patología , Antibacterianos/uso terapéutico , Brasil , Doxiciclina/uso terapéutico , Diagnóstico Precoz , Rickettsia rickettsii , Fiebre Maculosa de las Montañas Rocosas/tratamiento farmacológico , Enfermedades Cutáneas Bacterianas/tratamiento farmacológico , Piel/patologíaRESUMEN
American Tegumentary Leishmaniasis (ATL) is a chronic, non-contagious, infectious disease affecting millions of people worldwide. The timely and proper treatment is of great importance to prevent the disease from progressing to destructive and severe forms. Treatment for ATL recommended by the Brazilian Ministry of Health is similar for the whole country, regardless of the species of Leishmania. It is known that the response to treatment may vary with the strain of the parasite, the immune status of the patient and clinical form. We report the case of a healthy patient, coming from Manaus, Amazonas state, Brazil, who presented resistance to treatment with N-methyl-glutamine and liposomal amphotericin B, only being healed after using pentamidine.
Asunto(s)
Niño , Femenino , Humanos , Antiprotozoarios/uso terapéutico , Leishmaniasis Cutánea/tratamiento farmacológico , Pentamidina/uso terapéutico , Brasil , Resistencia a Medicamentos , Leishmaniasis Cutánea/patología , Resultado del TratamientoRESUMEN
American Tegumentary Leishmaniasis (ATL) is a chronic, non-contagious, infectious disease affecting millions of people worldwide. The timely and proper treatment is of great importance to prevent the disease from progressing to destructive and severe forms. Treatment for ATL recommended by the Brazilian Ministry of Health is similar for the whole country, regardless of the species of Leishmania. It is known that the response to treatment may vary with the strain of the parasite, the immune status of the patient and clinical form. We report the case of a healthy patient, coming from Manaus, Amazonas state, Brazil, who presented resistance to treatment with N-methyl-glutamine and liposomal amphotericin B, only being healed after using pentamidine.
Asunto(s)
Antiprotozoarios/uso terapéutico , Leishmaniasis Cutánea/tratamiento farmacológico , Pentamidina/uso terapéutico , Brasil , Niño , Resistencia a Medicamentos , Femenino , Humanos , Leishmaniasis Cutánea/patología , Resultado del TratamientoRESUMEN
Leprosy skin lesions are described as hypochromic or erythematous macules, pale erythematous or reddish-brown plaques, papules, nodules, and diffuse cutaneous infiltration, depending on the clinical form of the disease. They may be accompanied by hypo or anesthesia, alopecia, and hypo or anhidrosis. Verrucous lesions are now quite uncommon in leprosy. The literature is sparse, with only 25 reported cases of this association, especially in the lepromatous pole of the disease. This work is a report on two cases of lepromatous leprosy of long evolution, coursing with vegetant verrucous lesions.
Asunto(s)
Lepra Lepromatosa/patología , Adulto , Anciano de 80 o más Años , Progresión de la Enfermedad , Femenino , Dermatosis del Pie/patología , Humanos , Dermatosis de la Pierna/patologíaRESUMEN
Leprosy skin lesions are described as hypochromic or erythematous macules, pale erythematous or reddish-brown plaques, papules, nodules, and diffuse cutaneous infiltration, depending on the clinical form of the disease. They may be accompanied by hypo or anesthesia, alopecia, and hypo or anhidrosis. Verrucous lesions are now quite uncommon in leprosy. The literature is sparse, with only 25 reported cases of this association, especially in the lepromatous pole of the disease. This work is a report on two cases of lepromatous leprosy of long evolution, coursing with vegetant verrucous lesions.