Probiotic supplements and postoperative complications after tooth extractions and third molar surgery: a systematic review.

INTRODUCTION: Probiotics have gained considerable attention as intervention for various conditions in dentistry. The purpose of this review is to evaluate the current literature on the efficacy of probiotic supplements for alleviating symptoms after tooth extractions and third molar surgery. EVIDENCE ACQUISITION: We searched the PubMed and Google Scholar databases up to October 15, 2021 using pertinent keywords to retrieve relevant literature. Based on abstracts, the authors reviewed the full text papers, extracted key outcome data, and assessed the risk of bias. EVIDENCE SYNTHESIS: Four articles based on three RCT's were included of which three allowed compilation. There were no beneficial effects on the occurrence of postoperative infections or alveolitis, but we disclosed a significant trend towards less self-reported pain one week after the tooth extractions (RD -0.22; 95% CI -0.33; -0.11; P<0.05). Findings concerning swelling, discomfort and use of painkillers were inconsistent. CONCLUSIONS: Probiotic supplements may offer clinical benefits within oral surgery, such as alleviating pain after tooth extractions. However, the certainty of these findings was very low due to risk of bias, heterogeneity, and inconsistencies across the studies. Further and larger investigations are required to strengthen the level of evidence.

Ridge preservation using Collacone compared with an empty socket: a pilot study.

OBJECTIVES: The objective of this study was to evaluate the dimensional changes in alveolar bone and soft tissue after dental extraction/postextraction in alveoli filled/grafted with collagen (Collacone) compared with those left empty/ungrafted. STUDY DESIGN: Twenty-three patients with a single maxillary incisor to be extracted were included in the study. The patients were randomized into either the treatment group, receiving a collagen sponge, or into the control group with an empty alveolus. All participants were examined and followed with cone beam computed tomography and 3-dimensional soft tissue scanning procedures during the healing process. The outcomes were statistically evaluated with Mann-Whitney U tests. RESULTS: Seventeen patients were available for follow-up. The radiographic outcome showed an average loss of bone in the bucco-palatal width of 1.15 mm (range, 0.2-2.2) in the test group and 0.57 mm (range, 0-1.6) among the controls. There was no significant difference between the 2 groups (P = .092). The soft tissue topography height measurements revealed an average decrease of 1.737 mm (range, 0.118-2.872) in the test group and 1.899 mm (range, 0.454-3.014) in the control group. The difference was not significant (P = .847). CONCLUSION: The use of a Collacone collagen sponge does not enhance the bone and soft tissue healing outcome after extraction of an incisor in the maxilla compared with leaving the alveolus empty.

Vertical bone augmentation with titanium granule blocks in rabbit calvaria.

To determine whether it is possible to vertically augment bone utilizing a block graft from compressed titanium granules mainly used previously for contained bone defects and to determine whether there exists a difference in osteoconductive properties between the white and the grey granules. In 11 rabbits, 4 titanium blocks were inserted on each rabbit's skull bone according to a randomized scheme. These blocks were made from standardized compressed titanium granules. Type A: PTG grey, small granules (Pourus Titanium Granules, Tigran, Malmö, Sweden); Type B: PTG grey, large granules; Type C: PTG white, small granules; Type D: PTG white large granules. After 12 weeks, the animals were sacrificed and specimens were collected for histology and µCT scanning. From both the µCT and histology, it can be said that bone formation was successfully achieved for all groups, and the granules maintained their volume. The histomorphometric BA (bone area) evaluation in the entire grafted area presented that there were no statistical differences between all groups tested. The lowest 1/4 BA in contact with the rabbit skull presented that groups A and C presented the highest mean BA, and group A presented significantly higher BA than that of group D (p = 0,049). No significant differences were noted between groups A, B and C. Within the limitation of this study, no differences were noted between small white or grey PTG blocks. The large granules presented less bone ingrowth area compared to the small granules and this trend was regardless of the different PTG types. The entire grafted area was not filled with new bone suggesting that bone migration occurred mostly from the existing cortical bone side suggesting contact osteogenesis.

Periosteal expansion before local bone reconstruction using a new technique for measuring soft tissue profile stability: a clinical study.

PURPOSE: To evaluate the outcome of intraoral soft tissue expansion by measuring the profile change using objective 3D metering equipment and to evaluate localized bone grafting after soft tissue expansion with regard to gain of bone and complications. MATERIALS AND METHODS: Using a prospective study design, we asked patients with an osseous and soft tissue defect on the buccal aspect of the alveolar process to participate in this study. In 10 patients (experimental group) a self-inflatable soft tissue expander was placed under the periosteum. After 2 weeks, the expander was removed and a particulated onlay bone graft was placed in the expanded area, protected by a titanium mesh covered with a collagen membrane. Ten patients (reference group) were treated with a mandibular ramus bone block graft. The soft tissue profile was registered before each surgical procedure. The vertical and lateral dimensions of the bone grafts were noted at the grafting procedure and at the implant installation. P < .05 was considered significant. RESULTS: The mean soft tissue profile change was 2.9 ± 1.1 mm after soft tissue expansion and 2.3 ± 2.1 mm at implant placement in the experimental group compared with 1.5 ± 1.4 mm at implant placement in the reference group (P = .065). Two patients had minor perforations of the soft tissue expander. In the experimental group, the mean lateral bone augmentation after soft tissue expansion was 4.5 ± 1.3 mm, and after healing, it decreased to 3.9 ± 1.4 mm (P = .063). The mean vertical augmentation was 4.1 ± 1.7 mm and had decreased at implant placement to 3.0 ± 1.4 mm (P = .041). In the reference group, the mean lateral augmentation was 3.8 ± 0.8 mm, and after healing, it reduced to 2.7 ± 0.8 mm (P = .024). The mean vertical augmentation was 2.9 ± 0.9 mm, and after healing of the bone graft at implant placement, it was reduced to 1.6 ± 0.8 mm (P = .01). When smokers were excluded, there was significantly less resorption of the bone grafts in both lateral (P = .049) and vertical (P = .012) dimensions in the experimental group compared with the reference group. CONCLUSION: Hydrogel expansion of the periosteum is an applicable method to achieve a surplus of soft tissue to cover bone grafts. More refinements to the technique may be required to minimize complications, especially in smoking patients.

Periapical tissue response after use of intermediate restorative material, gutta-percha, reinforced zinc oxide cement, and mineral trioxide aggregate as retrograde root-end filling materials: a histologic study in dogs.

PURPOSE: To investigate the periapical tissue response of 4 different retrograde root-filling materials, ie, intermediate restorative material, thermoplasticized gutta-percha, reinforced zinc oxide cement (Super-EBA), and mineral trioxide aggregate (MTA), in conjunction with an ultrasonic root-end preparation technique in an animal model. MATERIALS AND METHODS: Vital roots of the third and fourth right mandibular premolars in 6 healthy mongrel dogs were apicectomized and sealed with 1 of the materials using a standardized surgical procedure. After 120 days, the animals were sacrificed and the specimens were analyzed radiologically, histologically, and scanning electron microscopically. The Fisher exact test was performed on the 2 outcome values. RESULTS: Twenty-three sections were analyzed histologically. Evaluation showed better re-establishment of the periapical tissues and generally lower inflammatory infiltration in the sections from teeth treated with the intermediate restorative material and the MTA. New root cement on the resected dentin surfaces was seen on all sections regardless of the used material. New hard tissue formation, directly on the surface of the material, was seen only in the MTA sections. There was no statistical difference in outcome among the tested materials. CONCLUSIONS: The results from this dog model favor the intermediate restorative material and MTA as retrograde fillings when evaluating the bone defect regeneration. MTA has the most favorable periapical tissue response when comparing the biocompatibility of the materials tested.

Super-EBA and IRM as root-end fillings in periapical surgery with ultrasonic preparation: a prospective randomized clinical study of 206 consecutive teeth.

OBJECTIVE: This study evaluated the treatment outcome after periapical surgery with the use of 2 different retrograde root-filling materials and the influence of 3 pre- and perioperative variables on the periapical healing. STUDY DESIGN: Two hundred six teeth in 164 patients were randomly allocated to receive either IRM or Super-EBA as a retrograde root-end seal. The teeth were reviewed 12 months after surgery. The influence of lesion size, lesion type, and orthograde root filling quality on healing was analyzed. RESULTS: One hundred ninety-four teeth in 153 patients were reviewed. Radiologic evaluation and clinical examination revealed 91% success rate for the IRM group and 82% for the Super-EBA group. There was no statistical significance in the healing outcome between the 2 groups (Fisher exact test). The analyzed pre- and perioperative variables had no significant influence on the treatment outcome (Z test). CONCLUSIONS: Both retrograde materials tested in this study can serve as a root-end seal in periapical infected teeth, according to the results of the healing outcome after 12 months' follow-up.

Frontal bone and modified zygomatic implants for retention of a nasal prosthesis: Surgical planning using a three-dimensional computer software program.

Implants integrated into bone have revolutionised the retention of total nasal prostheses. However, it may be difficult to identify available sites for placement of the implant after excision. In addition, it is ideal to minimise wide bony exposure after radiotherapy to avoid compromising the blood supply. In this paper we describe a technique for accurate placement of frontal bone and customised zygomatic implants using a computer-designed and fabricated surgical guide with a minimal access flap.

Periapical surgery using ultrasonic preparation and thermoplasticized gutta-percha with AH Plus sealer or IRM as retrograde root-end fillings in 160 consecutive teeth: a prospective randomized clinical study.

OBJECTIVE: The aim of this study was to evaluate the healing outcome after periapical surgery with an ultrasonic cleaning technique in conjunction with the use of either of 2 different retrograde root-filling materials in teeth with apical periodontitis. STUDY DESIGN: One hundred sixty teeth in 139 consecutive patients were randomly allocated into 2 groups receiving either IRM or thermoplasticized gutta-percha (GP) with AH Plus sealer as a retrograde root-end seal. The patients were reviewed 12 months after surgery. The results were analyzed with Fisher exact test. RESULTS: One hundred forty-seven teeth in 131 patients were reviewed. Radiologic evaluation and clinical examination showed an 85% success rate for the IRM group and 90% for GP group. There was no statistical significance between the 2 groups. CONCLUSION: Both tested materials, IRM and GP, are suitable as retrograde root-end filling materials in conjunction with ultrasonic root-end preparation according to the results of the healing outcome after 12 months follow-up.

Prospective study of periapically infected teeth treated with periapical surgery including ultrasonic preparation and retrograde intermediate restorative material root-end fillings.

PURPOSE: The aim of this prospective study was to evaluate the current method of periapical surgery at the Maxillofacial Unit, Halmstad Hospital, which included ultrasonic root-end preparation and the use of intermediate restorative material as a root-end filling material. PATIENTS AND METHODS: Fifty-five consecutive patients with a total of 56 treated teeth, within the close vicinity of the hospital, were included in the study during a period of 10 months in 2002. Teeth with advanced periodontal bone loss or presence of root fractures were excluded from the study. RESULTS: All teeth but 1 were followed up after 1 year (12-19 months). Radiological evaluation (complete or incomplete healing) and clinical examination showed an 80% success rate. Twenty percent of the patients were stated as failures (uncertain healing and unsatisfactory healing). The success rate was highest among incisors (100%) and lowest among molars and premolars (78% and 69%, respectively). CONCLUSION: Compared with other studies, these findings seemed to be a bit inferior regarding success rate. However, our study population was not selected for the study purpose but rather represented the true clinical variety taken care of in our practice.

Description of a technique for evaluation of three-dimensional shape alterations in soft tissue after intra oral bone reconstruction.

Equipment from GFMesstechnik, Germany, for three-dimensional (3D) measurements of topography alterations was tested in an intra oral situation. A patient with previous loss of tooth 21 due to trauma planned for local bone grafting procedure together with a titanium mesh and later implant insertion was signed as a trial. Pre- and postoperative measurements of the buccal contour in maxillary anterior region were performed with the 3D equipment and the pictures were evaluated in a software programme. The evaluation showed ability to reproduce numerical volume changes in the buccal soft tissue in the operated area. The contour changes can be displayed as a diagram change as well, with possibility to make numerical calculations. We believe this is an excellent system to use in long-term follow-ups of the soft tissue changes after intra oral reconstructive procedures. The procedure is a rapid, accurate, and harmless procedure and can be performed directly on the patient.