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1.
Lab Chip ; 13(7): 1247-56, 2013 Apr 07.
Artículo en Inglés | MEDLINE | ID: mdl-23429747

RESUMEN

Utilizing a tunable photonic crystal resonant reflector as a mirror of an external cavity laser cavity, we demonstrate a new type of label-free optical biosensor that achieves a high quality factor through the process of stimulated emission, while at the same time providing high sensitivity and large dynamic range. The photonic crystal is fabricated inexpensively from plastic materials, and its resonant wavelength is tuned by adsorption of biomolecules on its surface. Gain for the lasing process is provided by a semiconductor optical amplifier, resulting in a simple detection instrument that operates by normally incident noncontact illumination of the photonic crystal and direct back-reflection into the amplifier. We demonstrate single-mode, biomolecule-induced tuning of the continuous-wave laser wavelength. Because the approach incorporates external optical gain that is separate from the transducer, the device represents a significant advance over previous passive optical resonator biosensors and laser-based biosensors.


Asunto(s)
Técnicas Biosensibles/instrumentación , Rayos Láser , ADN/genética , Hibridación de Ácido Nucleico , Propiedades de Superficie
2.
Opt Express ; 20(13): 14292-301, 2012 Jun 18.
Artículo en Inglés | MEDLINE | ID: mdl-22714491

RESUMEN

Continuous tuning over a 1.6 THz region in the near-infrared (842.5-848.6 nm) has been achieved with a hybrid ring/external cavity laser having a single, optically-driven grating reflector and gain provided by an injection-seeded semiconductor amplifier. Driven at 532 nm and incorporating a photonic crystal with an azobenzene overlayer, the reflector has a peak reflectivity of ~80% and tunes at the rate of 0.024 nm per mW of incident green power. In a departure from conventional ring or external cavity lasers, the frequency selectivity for this system is provided by the passband of the tunable photonic crystal reflector and line narrowing in a high gain amplifier. Sub - 0.1 nm linewidths and amplifier extraction efficiencies above 97% are observed with the reflector tuned to 842.5 nm.


Asunto(s)
Amplificadores Electrónicos , Rayos Láser , Semiconductores , Diseño Asistido por Computadora , Cristalización , Diseño de Equipo , Análisis de Falla de Equipo , Fotones
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