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2.
J Dent Educ ; 88(2): 176-189, 2024 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-37953678

RESUMEN

OBJECTIVES: Hands-on learning environments can challenge learners' wellbeing in dental education, given their unfamiliarity with students. As today's learners are more aware about their wellbeing needs, it is important to explore the depth and complexity of the challenges they experience and provide them with the necessary support strategies. This study aims to identify the challenges and sources of cognitive overload of early years' dental students across two time-points: 2012 and 2022. We also aim to describe the students' recommendations for future program revision considerations to support students' wellbeing. METHODS: This study employs both qualitative and quantitative methods. Qualitatively, we utilized an Interpretive Description approach and conducted focus groups with first-year dental students in 2023. Quantitively, we utilized first-year dental students' responses to the Study Habits survey administered in 2012/2013. RESULTS: Five main concerns and sources of cognitive load emerged from the focus groups and survey data: steepness of the learning curve, inconsistent feedback, stigma around asking for support, structural and organizational challenges, and lack of resources. Students also identified several suggestions to support their wellbeing, including time, instructor support, non-graded exercises, additional resources, and re-organizing the curriculum. CONCLUSION: This study adopts a wellbeing lens to examine students' transition into hands-on learning activities. These findings were utilized to propose the TIPSS Support Framework (Time, Instructor Capacity Building, Peer Learning and Other Resources, Safe Learning Spaces, and Spiraling Curriculum). The proposed model can serve as a prototype for future studies to explore its applicability and effectiveness in other dental programs.


Asunto(s)
Aprendizaje , Estudiantes de Odontología , Humanos , Estudiantes de Odontología/psicología , Curriculum , Retroalimentación , Educación en Odontología/métodos
3.
Eur Heart J Qual Care Clin Outcomes ; 8(3): 289-297, 2022 05 05.
Artículo en Inglés | MEDLINE | ID: mdl-34849707

RESUMEN

AIMS: To explore the impact of incorporating a faster cardiac magnetic resonance (CMR) imaging protocol in a low-middle-income country (LMIC) and using the result to guide chelation in transfusion-dependent patients. METHODS AND RESULTS: A prospective UK-India collaborative cohort study was conducted in two cities in India. Two visits 13 months apart included clinical assessment and chelation therapy recommendations based on rapid CMR results. Participants were recruited by the local patient advocate charity, who organized the patient medical camps. The average scanning time was 11.3 ± 2.5 min at the baseline and 9.8 ± 2.4 min (P < 0.001) at follow-up. The baseline visit was attended by 103 patients (mean age 25 years) and 83% attended the second assessment. At baseline, 29% had a cardiac T2* < 20 ms, which represents significant iron loading, and 12% had left ventricular ejection fraction <60%, the accepted lower limit in this population. Only 3% were free of liver iron (T2* ≥ 17 ms). At 13 months, more patients were taking intensified dual chelation therapy (43% vs. 55%, P = 0.002). In those with cardiac siderosis (baseline T2* < 20 ms), there was an improvement in T2*-10.9 ± 5.9 to 13.5 ± 8.7 ms, P = 0.005-and fewer were classified as having clinically important cardiac iron loading (T2* < 20 ms, 24% vs. 16%, P < 0.001). This is the first illustration in an LMIC that incorporating CMR results into patient management plans can improve cardiac iron loading. CONCLUSION: For thalassaemia patients in an LMIC, a simplified CMR protocol linked to therapeutic recommendation via the patient camp model led to enhanced chelation therapy and a reduction in cardiac iron in 1 year.


Asunto(s)
Talasemia , Talasemia beta , Adulto , Terapia por Quelación/métodos , Estudios de Cohortes , Humanos , Hierro , Imagen por Resonancia Magnética , Estudios Prospectivos , Volumen Sistólico , Talasemia/terapia , Función Ventricular Izquierda , Talasemia beta/patología , Talasemia beta/terapia
4.
J Alzheimers Dis ; 75(2): 547-557, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-32310169

RESUMEN

BACKGROUND: Alzheimer's disease (AD) is characterized by amyloid-ß plaques, neurofibrillary tangles, and regional cerebral glucose hypometabolism. Providing an alternative metabolic substrate, such as ketone bodies, may be a viable therapeutic option. OBJECTIVE: The objective was to determine the efficacy and safety of the AC-1204 formulation of caprylic triglyceride administered daily for 26 weeks in APOE4 non-carrier participants with mild-to-moderate AD. METHODS: In a double-blind, placebo-controlled, randomized study (AC-12-010, NOURISH AD, NCT01741194), 413 patients with mild-to-moderate probable AD were stratified by APOE genotype and randomized (1 : 1) to receive either placebo or AC-1204 for 26 weeks. The primary outcome was the change from baseline to week 26 on the 11-item Alzheimer's Disease Assessment Scale - Cognitive subscale (ADAS-Cog11) among APOE4 non-carriers. The key secondary outcome was the change from baseline to week 26 in the Alzheimer's Disease Cooperative Study - Clinician's Global Impression of Change scale. RESULTS: Administration of AC-1204 was safe and well-tolerated. Mean changes from baseline in the primary outcome at 26 weeks in ADAS-Cog11 for placebo (n = 138) was 0.0 and for AC-1204 (n = 137) was 0.6 (LS differences of mean - 0.761, p = 0.2458) and secondary outcome measures failed to detect any drug effects. CONCLUSION: The AC-1204 formulation of caprylic triglyceride failed to improve cognition or functional ability in subjects with mild-to-moderate AD. The lack of efficacy observed in this study may have several contributing factors including a lower ketone body formation from AC-1204 than expected and a lack of decline in the patients receiving placebo.


Asunto(s)
Enfermedad de Alzheimer/tratamiento farmacológico , Cognición/efectos de los fármacos , Triglicéridos/uso terapéutico , Anciano , Anciano de 80 o más Años , Enfermedad de Alzheimer/psicología , Método Doble Ciego , Femenino , Humanos , Masculino , Resultado del Tratamiento , Triglicéridos/administración & dosificación
5.
Glob Public Health ; 14(2): 200-213, 2019 02.
Artículo en Inglés | MEDLINE | ID: mdl-29764294

RESUMEN

Expanding access to maternal, newborn and child health (MNCH) services in traditional societies is a public health challenge, often complicated by cultural and religious beliefs about what is permitted or not permitted within a faith group. This is particularly true in the Muslim majority North of Nigeria, where deep suspicions of Western public health programmes, coupled with failing and underfunded health system, have led to the emergence of a new generation of Muslim Opinion Leaders (MOLs) with counter-narratives against family planning, immunisation and nutrition programmes. This paper reports on an innovative project implemented under the Saving Lives at Birth global partnership programme, where conservative MOLs transformed as champions were engaged as health communicators to train health providers on correct religious precepts related to MNCH. A matched subject type of study design was used to compare healthcare providers' performance in control and intervention health facilities. The result indicates a significant difference both in perception and in practices between healthcare providers in intervention and control facilities, with respect to MNCH uptake. This paper highlights the need for renewed focus on engaging faith leaders and organisations in health communication and service delivery and presents a model of sustainable engagement of champions in MNCH.


Asunto(s)
Comercio , Salud Global , Personal de Salud/educación , Servicios de Salud Materna , Naciones Unidas , Niño , Servicios de Salud del Niño , Femenino , Humanos , Entrevistas como Asunto , Islamismo , Liderazgo , Nigeria , Embarazo , Investigación Cualitativa , Determinantes Sociales de la Salud
6.
J Dent Educ ; 81(8): 937-947, 2017 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-28765438

RESUMEN

The aims of this exploratory study were to explore dental faculty members' views and beliefs regarding knowledge, the dental profession, and teaching and learning and to determine how these views related to their problem-based learning (PBL) instructional practices. Prior to a PBL in dental education conference held in 2011, all attendees were invited to complete a survey focused on their pedagogical beliefs and practices in PBL. Out of a possible 55 participants, 28 responded. Additionally, during the conference, a forum was held in which preliminary survey findings were shared and participants contributed to focus group data collection. The forum results served to validate and bring deeper understanding to the survey findings. The conference participants who joined the forum (N=32) likely included some or many of the anonymous respondents to the survey, along with additional participants interested in dental educators' beliefs. The findings of the survey and follow-up forum indicated a disconnect between dental educators' reported views of knowledge and their pedagogical practices in a PBL environment. The results suggested that the degree of participants' tolerance of uncertainty in knowledge and the discrepancy between their epistemological and ontological beliefs about PBL pedagogy influenced their pedagogical choices. These findings support the idea that learner-centered, inquiry-based pedagogical approaches such as PBL may create dissonance between beliefs about knowledge and pedagogical practice that require the building of a shared understanding of and commitment to curricular goals prior to implementation to ensure success. The methods used in this study can be useful tools for faculty development in PBL programs in dental education.


Asunto(s)
Curriculum , Educación en Odontología/métodos , Docentes de Odontología/psicología , Aprendizaje Basado en Problemas , Grupos Focales , Humanos , Aprendizaje , Enseñanza
7.
J Health Econ Outcomes Res ; 5(1): 1-15, 2017.
Artículo en Inglés | MEDLINE | ID: mdl-37664687

RESUMEN

Background: Pain is a leading cause of admission to the emergency department (ED) and moderate-to-severe acute pain in medically supervised settings is often treated with intravenous (IV) opioids. With novel noninvasive analgesic products in development for this indication, it is important to assess the costs associated with IV administration of opioids. Materials and Methods: A retrospective observational study of data derived from the Premier database was conducted. All ED encounters of adult patients treated with IV opioids during a 2-year time period, who were charged for at least one IV opioid administration in the ED were included. Hospital reported costs were used to estimate the costs to administer IV opioids. Results: Over a 24 month-period, 7.3 million encounters, which included the administration of IV opioids took place in 614 US EDs. The mean cost per encounter of IV administration of an initial dose of the three most frequently prescribed opioids were: morphine $145, hydromorphone $146, and fentanyl $147. The main driver of the total costs is the cost of nursing time and equipment cost to set up and maintain an IV infusion ($140 ± 60). Adding a second dose of opioid, brings the average costs to $151-$154. If costs associated with the management of opioid-related adverse events and IV-related complications are also added, the total costs can amount to $269-$273. Of these 7.3 million encounters, 4.3 million (58%) did not lead to hospital admission of the patient and, therefore, the patient may have only required an IV catheter for opioid administration. Conclusions: IV opioid use in the ED is indicated for moderate-to-severe pain but is associated with significant costs. In subjects who are discharged from the ED and may not have required an IV for reasons other than opioid administration, rapid-onset analgesics for moderate-to-severe pain that do not require IV administration could lead to direct cost reductions and improved care.

8.
J Dent Educ ; 80(4): 422-9, 2016 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-27037450

RESUMEN

This article describes how the University of British Columbia Faculty of Dentistry reached consensus on essential basic biomedical science objectives for DMD students and applied the information to the renewal of its DMD curriculum. The Delphi Method was used to build consensus among dental faculty members and students regarding the relevance of over 1,500 existing biomedical science objectives. Volunteer panels of at least three faculty members (a basic scientist, a general dentist, and a dental specialist) and a fourth-year dental student were formed for each of 13 biomedical courses in the first two years of the program. Panel members worked independently and anonymously, rating each course objective as "need to know," "nice to know," "irrelevant," or "don't know." Panel members were advised after each round which objectives had not yet achieved a 75% consensus and were asked to reconsider their ratings. After a maximum of three rounds to reach consensus, a second group of faculty experts reviewed and refined the results to establish the biomedical science objectives for the renewed curriculum. There was consensus on 46% of the learning objectives after round one, 80% after round two, and 95% after round three. The second expert group addressed any remaining objectives as part of its review process. Only 47% of previous biomedical science course objectives were judged to be essential or "need to know" for the general dentist. The consensus reached by participants in the Delphi Method panels and a second group of faculty experts led to a streamlined, better integrated DMD curriculum to prepare graduates for future practice.


Asunto(s)
Consenso , Curriculum , Educación en Odontología , Aprendizaje , Ciencia/educación , Disciplinas de las Ciencias Biológicas/educación , Colombia Británica , Técnica Delphi , Odontólogos , Educación Médica , Docentes de Odontología , Humanos , Especialidades Odontológicas , Estudiantes de Odontología
9.
Afr J Reprod Health ; 20(3): 55-61, 2016 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-29553195

RESUMEN

As global impact investors gear up to support roll out of the Sustainable Development Goals in the developing world, African CSOs are urged to ensure that governments shift health funding sources away from aid and loans to innovative domestic funding sources which prioritize health. To do so, African CSOs require support to build their capacity for policy and budget advocacy. Governments and development partners have failed to invest in long term capacity building projects for indigenous NGOs and instead support INGOs to push the health advocacy agenda forward. In Nigeria, the Gates foundation has risen to the challenge of building capacity of indigenous NGOs for social accountability in child and family health. The 3 year pilot project - Partnership for Advocacy in Child and Family Health Project (PACFaH) mainstreams capacity building as an effective implementation strategy for 8 indigenous NGOs to deliver on - policy; budgetary; legislative; and administrative advocacy in four issue areas: 1) family planning; 2) nutrition; 3) routine immunization; and 4) reduction of under-5 deaths from diarrhea and pneumonia. This paper documents the achievements of the eight advocacy NGOs in PACFaH, at midterm and notes that while there have been challenges, working through capacity building as an implementation strategy has enabled the local groups in the delivery of evidence based advocacy.

10.
J Obes ; 2015: 693829, 2015.
Artículo en Inglés | MEDLINE | ID: mdl-26199740

RESUMEN

BACKGROUND: Lifestyle intervention programs after bariatric surgery have been suggested to maximise health outcomes. This pilot study aimed to investigate the feasibility and impact of an 8-week combined supervised exercise with nutritional-behavioral intervention following Roux-en-Y gastric bypass and sleeve gastrectomy. METHODS: Eight female patients (44 ± 8 years old, BMI = 38.5 ± 7.2 kg m(-2)) completed the program. Before and after intervention, anthropometric measures, six-minute walk test (6MWT), physical activity level, eating behavior, and quality of life (QoL) were assessed. Percentage weight loss (%WL) outcomes were compared with a historical matched control group. RESULTS: The program significantly improved functional capacity (mean increment in 6MWT was 127 ± 107 meters, p = 0.043), increased strenuous intensity exercise (44 ± 49 min/week, p = 0.043), increased consumption of fruits and vegetables (p = 0.034), reduced consumption of ready meals (p = 0.034), and improved "Change in Health" in QoL domain (p = 0.039). The intervention group exhibited greater %WL in the 3-12-month postsurgery period compared to historical controls, 12.2 ± 7.5% versus 5.1 ± 5.4%, respectively (p = 0.027). CONCLUSIONS: Lifestyle intervention program following bariatric surgery is feasible and resulted in several beneficial outcomes. A large randomised control trial is now warranted.


Asunto(s)
Terapia Conductista/métodos , Ejercicio Físico , Gastrectomía , Derivación Gástrica , Terapia Nutricional/métodos , Obesidad Mórbida/terapia , Pérdida de Peso , Adulto , Terapia Combinada , Estudios de Factibilidad , Femenino , Humanos , Obesidad Mórbida/prevención & control , Obesidad Mórbida/psicología , Proyectos Piloto , Calidad de Vida , Conducta de Reducción del Riesgo , Resultado del Tratamiento
11.
J Dent Educ ; 79(3): 286-94, 2015 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-25729022

RESUMEN

The purpose of this study was to explore the use of cognitive task analysis to inform the teaching of psychomotor skills and cognitive strategies in clinical tasks in dental education. Methods used were observing and videotaping an expert at one dental school thinking aloud while performing a specific preclinical task (in a simulated environment), interviewing the expert to probe deeper into his thinking processes, and applying the same procedures to analyze the performance of three second-year dental students who had recently learned the analyzed task and who represented a spectrum of their cohort's ability to undertake the procedure. The investigators sought to understand how experts (clinical educators) and intermediates (trained students) overlapped and differed at points in the procedure that represented the highest cognitive load, known as "critical incidents." Findings from this study and previous research identified possible limitations of current clinical teaching as a result of expert blind spots. These findings coupled with the growing evidence of the effectiveness of peer teaching suggest the potential role of intermediates in helping novices learn preclinical dentistry tasks.


Asunto(s)
Cognición , Educación en Odontología , Análisis y Desempeño de Tareas , Enseñanza/métodos , Estudios de Cohortes , Toma de Decisiones , Restauración Dental Permanente/métodos , Operatoria Dental/educación , Docentes de Odontología , Humanos , Aprendizaje , Mentores , Grupo Paritario , Proyectos Piloto , Desempeño Psicomotor , Estudiantes de Odontología , Pensamiento , Grabación de Cinta de Video
12.
Ann Fam Med ; 13(2): 168-75, 2015 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-25755039

RESUMEN

PURPOSE: There is a strong push in the United States to evaluate whether the patient-centered medical home (PCMH) model produces desired results. The explanatory and contextually based questions of how and why PCMH succeeds in different practice settings are often neglected. We report the development of a comprehensive, mixed qualitative-quantitative evaluation set for researchers, policy makers, and clinician groups. METHODS: To develop an evaluation set, the Brown Primary Care Transformation Initiative convened a multidisciplinary group of PCMH experts, reviewed the PCMH literature and evaluation strategies, developed key domains for evaluation, and selected or created methods and measures for inclusion. RESULTS: The measures and methods in the evaluation set (survey instruments, PCMH meta-measures, patient outcomes, quality measures, qualitative interviews, participant observation, and process evaluation) are meant to be used together. PCMH evaluation must be sufficiently comprehensive to assess and explain both the context of transformation in different primary care practices and the experiences of diverse stakeholders. In addition to commonly assessed patient outcomes, quality, and cost, it is critical to include PCMH components integral to practice culture transformation: patient and family centeredness, authentic patient activation, mutual trust among practice employees and patients, and transparency, joy, and collaboration in delivering and receiving care in a changing environment. CONCLUSIONS: This evaluation set offers a comprehensive methodology to enable understanding of how PCMH transformation occurs in different practice settings. This approach can foster insights about how transformation affects critical outcomes to achieve meaningful, patient-centered, high-quality, and cost-effective sustainable change among diverse primary care practices.


Asunto(s)
Guías como Asunto , Atención Dirigida al Paciente/normas , Garantía de la Calidad de Atención de Salud/métodos , Calidad de la Atención de Salud , Personal Administrativo , Conducta Cooperativa , Humanos , Investigación Cualitativa , Proyectos de Investigación , Estados Unidos
13.
J Clin Nurs ; 23(13-14): 1857-65, 2014 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-24942268

RESUMEN

AIMS AND OBJECTIVES: To evaluate the training needs and awareness of childhood sexual abuse amongst clinical staff taking cervical screening samples in one inner city primary care trust. BACKGROUND: Studies exploring sexual abuse and nonparticipation in cervical screening have demonstrated that women can experience re-traumatisation if care during examinations is insensitive to their particular needs. DESIGN: This was a mixed methods, service evaluation in three phases. METHODS: A literature review, a questionnaire to cervical screening staff in an inner city primary care trust and a focus group of four staff drawn from questionnaire respondents to explore themes raised in the questionnaire data. RESULTS: Data analysis of both quantitative and qualitative data showed that clinical staff underestimated the frequency of childhood sexual abuse although they were aware of the difficulties and reluctance some women experience undergoing gynaecological examinations. When women did disclose childhood sexual abuse or when staff suspected a history of childhood sexual abuse, staff reported feeling unsure of how they should proceed. There was no support or clinical supervision, and unmet training needs were identified. CONCLUSIONS: Nurses expressed anxiety around the potential of the screening test to cause more harm than good and at their inability to provide more help than listening. Staff wanted support and further training after completing their cervical screening training course to assist in their provision of sensitive care to patients who have experienced childhood sexual abuse. RELEVANCE TO CLINICAL PRACTICE: Whilst our results cannot be generalised to a wider population, they may be meaningful for the community of cervical screening takers. We argue that screening staff require further training and professional support (clinical supervision) to increase their confidence when providing safe and sensitive practice for childhood sexual abuse survivors. If staff feel more confident and competent when responding to disclosure of childhood sexual abuse in screening situations, women who have experienced childhood sexual abuse might participate in the screening programme more readily.


Asunto(s)
Cuello del Útero/patología , Abuso Sexual Infantil/psicología , Examen Físico , Autoimagen , Adulto , Anciano , Niño , Inglaterra , Femenino , Humanos , Tamizaje Masivo , Persona de Mediana Edad , Evaluación en Enfermería , Medicina Estatal , Encuestas y Cuestionarios , Salud Urbana
14.
Am J Med Qual ; 29(6): 517-21, 2014.
Artículo en Inglés | MEDLINE | ID: mdl-24101683

RESUMEN

Mercy Hospital Springfield is a tertiary care facility with 32 000 discharges and 15 000 inpatient surgeries in 2011. From June 2009 through January 2011, a stable inpatient elective neurosurgery infection rate of 2.15% was observed. The failure mode and effects analysis (FMEA) methodology to reduce inpatient neurosurgery infections was utilized. Following FMEA implementation, overall elective neurosurgery infection rates were reduced to 1.51% and sustained through May 2012. Compared with baseline, the post-FMEA deep-space and organ infection rate was reduced by 41% (P = .052). Overall hospital inpatient clean surgery infection rates for the same time frame did not decrease to the same extent, suggesting a specific effect of the FMEA. The study team believes that the FMEA interventions resulted in 14 fewer expected infections, $270 270 in savings, a 168-day reduction in expected length of stay, and 22 fewer readmissions. Given the serious morbidity and cost of health care-associated infections, the study team concludes that FMEA implementation was clinically cost-effective.


Asunto(s)
Análisis de Modo y Efecto de Fallas en la Atención de la Salud/métodos , Procedimientos Neuroquirúrgicos/efectos adversos , Mejoramiento de la Calidad/organización & administración , Infección de la Herida Quirúrgica/prevención & control , Ahorro de Costo/métodos , Costos de la Atención en Salud , Humanos , Tiempo de Internación/economía , Tiempo de Internación/estadística & datos numéricos , Procedimientos Neuroquirúrgicos/normas , Infección de la Herida Quirúrgica/economía , Infección de la Herida Quirúrgica/epidemiología , Centros de Atención Terciaria/economía , Centros de Atención Terciaria/organización & administración , Centros de Atención Terciaria/normas , Centros de Atención Terciaria/estadística & datos numéricos
15.
Afr J Reprod Health ; 16(2): 231-40, 2012 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-22916555

RESUMEN

This article explores the pattern of early marriage in Africa. It focuses on the sub-Saharan region as an area with the highest rates of early marriage in the world. The harmful effects of early marriage are explored in terms of impact on the health, education and economic well-being of young girls. The paper outlines a framework for analyzing global, regional and local initiatives to curb early marriage and examines the application of these interventions in sub-Saharan countries. Regional patterns are then examined and countries which have made progress in reducing age of marriage are compared to countries in which age of marriage amongst girls has reminded low. The paper concludes on the note that countries with the highest rates of early marriage are also the countries with the highest rates of poverty and highest population growth rates. The paper argues for a sub-regional strategy to address the problem of early marriage in the zone with the highest incidence.


Asunto(s)
Matrimonio , Adolescente , Adulto , África del Sur del Sahara , Niño , Defensa del Niño , Protección a la Infancia/legislación & jurisprudencia , Niños Huérfanos , Servicios de Planificación Familiar , Femenino , Humanos , Matrimonio/legislación & jurisprudencia , Matrimonio/estadística & datos numéricos , Matrimonio/tendencias , Abandono Escolar/estadística & datos numéricos , Adulto Joven
16.
Rural Remote Health ; 12: 1908, 2012.
Artículo en Inglés | MEDLINE | ID: mdl-22239835

RESUMEN

INTRODUCTION: Health workforce shortages are a major problem in rural areas. Australian medical schools have implemented a number of rural education and training interventions aimed at increasing medical graduates' willingness to work in rural areas. These initiatives include recruiting students from rural backgrounds, delivering training in rural areas, and providing all students with some rural exposure during their medical training. However there is little evidence regarding the impact of rural exposure versus rural origin on workforce outcomes. The aim of this study is to identify and assess factors affecting preference for future rural practice among medical students participating in the Australian Rural Clinical Schools (RCS) Program. METHODS: Questionnaires were distributed to 166 medical students who had completed their RCS term in 2006; 125 (75%) responded. Medical students were asked about their preferred location and specialty for future practice, their beliefs about rural work and life, and the impact of the RCS experience on their future rural training and practice preferences. RESULTS: Almost half the students (47%; n=58) self-reported a 'rural background'. Significantly, students from rural backgrounds were 10 times more likely to prefer to work in rural areas when compared with other students (p<0.001). For those preferring general practice, 80% (n=24) wished to do so rurally. Eighty-five per cent (n=105) of students agreed that their RCS experience increased their interest in rural training and practice with 62% (n=75) of students indicating a preference for rural internship/basic training after their RCS experience. A substantial percentage (86%; n=108) agreed they would consider rural practice after their RCS experience. CONCLUSIONS: This baseline study provides significant evidence to support rural medical recruitment and retention through education and training, with important insights into the factors affecting preference for future rural practice. By far the most significant predictor of rural practice intention is recruitment of students with a rural background who also undertake an RCS placement. This research also demonstrates significant demand for post-graduate rural training places, including specialty places, as RCS graduates become junior doctors and vocational trainees.


Asunto(s)
Actitud del Personal de Salud , Selección de Profesión , Selección de Personal/organización & administración , Ubicación de la Práctica Profesional , Servicios de Salud Rural , Estudiantes de Medicina/psicología , Adulto , Australia/epidemiología , Competencia Clínica , Femenino , Humanos , Internado y Residencia/organización & administración , Satisfacción en el Trabajo , Masculino , Persona de Mediana Edad , Especialización , Encuestas y Cuestionarios , Universidades , Recursos Humanos
17.
Eur J Hum Genet ; 19(6): 634-9, 2011 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-21386874

RESUMEN

Gilles de la Tourette syndrome is a complex neuropsychiatric disorder with a strong genetic basis. We identified a male patient with Tourette syndrome-like tics and an apparently balanced de novo translocation [46,XY,t(2;7)(p24.2;q31)]. Further analysis using array comparative genomic hybridisation (CGH) revealed a cryptic deletion at 7q31.1-7q31.2. Breakpoints disrupting this region have been reported in one isolated and one familial case of Tourette syndrome. In our case, IMMP2L, a gene coding for a human homologue of the yeast inner mitochondrial membrane peptidase subunit 2, was disrupted by the breakpoint on 7q31.1, with deletion of exons 1-3 of the gene. The IMMP2L gene has previously been proposed as a candidate gene for Tourette syndrome, and our case provides further evidence of its possible role in the pathogenesis. The deleted region (7q31.1-7q31.2) of 7.2 Mb of genomic DNA also encompasses numerous genes, including FOXP2, associated with verbal dyspraxia, and the CFTR gene.


Asunto(s)
Puntos de Rotura del Cromosoma , Cromosomas Humanos Par 7/genética , ADN/análisis , Endopeptidasas/genética , Tics/genética , Síndrome de Tourette , Apraxias/genética , Apraxias/fisiopatología , Cromosomas Humanos Par 7/ultraestructura , Hibridación Genómica Comparativa , Regulador de Conductancia de Transmembrana de Fibrosis Quística/deficiencia , Regulador de Conductancia de Transmembrana de Fibrosis Quística/genética , Endopeptidasas/metabolismo , Exones , Factores de Transcripción Forkhead/deficiencia , Factores de Transcripción Forkhead/genética , Humanos , Hibridación Fluorescente in Situ , Masculino , Análisis de Secuencia por Matrices de Oligonucleótidos , Linaje , Eliminación de Secuencia , Tics/fisiopatología , Síndrome de Tourette/genética , Síndrome de Tourette/fisiopatología , Translocación Genética
18.
Aust J Prim Health ; 16(1): 104-7, 2010.
Artículo en Inglés | MEDLINE | ID: mdl-21133307

RESUMEN

Collaborations between researchers, policy makers, service providers and community members are critical to the journey of health service reform. Challenges are multifaceted and complex. Partners come with a variety of challenging agendas, value sets and imperatives, and see the drivers for reform from different perspectives. Different skills are required for managing the partnership and for providing academic leadership, and different structural frameworks need to be put in place for each task in each project. We have found through a series of partnerships across our research theme of healthy ageing, and consequent translation into policy and practice, that significant and innovative effort is required for both the collaboration and the research to succeed. A shared understanding of the issues and challenges is a start, but not sufficient for longer-term success. In addition to managing the research, our experience has demonstrated the need to understand the different challenges faced by each of the partners, recognise and respect personal and organisational value systems, and to establish separate mechanisms to manage strong egos alongside, but outside of, the research process.


Asunto(s)
Redes Comunitarias/organización & administración , Relaciones Comunidad-Institución , Reforma de la Atención de Salud/organización & administración , Servicios de Salud para Ancianos/organización & administración , Redes Comunitarias/tendencias , Participación de la Comunidad , Conducta Cooperativa , Reforma de la Atención de Salud/métodos , Personal de Salud , Servicios de Salud para Ancianos/tendencias , Humanos , Relaciones Interinstitucionales , Formulación de Políticas , Investigadores , Tasmania
19.
Hum Mutat ; 30(7): 1082-92, 2009 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-19388127

RESUMEN

Genomic microarrays have been implemented in the diagnosis of patients with unexplained mental retardation. This method, although revolutionizing cytogenetics, is still limited to the detection of rare de novo copy number variants (CNVs). Genome-wide single nucleotide polymorphism (SNP) microarrays provide high-resolution genotype as well as CNV information in a single experiment. We hypothesize that the widespread use of these microarray platforms can be exploited to greatly improve our understanding of the genetic causes of mental retardation and many other common disorders, while already providing a robust platform for routine diagnostics. Here we report a detailed validation of Affymetrix 500k SNP microarrays for the detection of CNVs associated to mental retardation. After this validation we applied the same platform in a multicenter study to test a total of 120 patients with unexplained mental retardation and their parents. Rare de novo CNVs were identified in 15% of cases, showing the importance of this approach in daily clinical practice. In addition, much more genomic variation was observed in these patients as well as their parents. We provide all of these data for the scientific community to jointly enhance our understanding of these genomic variants and their potential role in this common disorder.


Asunto(s)
Discapacidad Intelectual/genética , Cariotipificación , Polimorfismo de Nucleótido Simple , Dosificación de Gen , Variación Genética , Heterocigoto , Humanos , Análisis de Secuencia por Matrices de Oligonucleótidos , Juego de Reactivos para Diagnóstico/normas , Disomía Uniparental
20.
Rural Remote Health ; 7(2): 705, 2007.
Artículo en Inglés | MEDLINE | ID: mdl-17465686

RESUMEN

INTRODUCTION: Australia is a country with a relatively small rural population dispersed over an enormous area. Issues similar to how best to deliver health services and recruit health professionals to rural areas exist in other countries. For professional and lifestyle reasons, most specialist doctors (including emergency medicine specialists), choose to live and work in major metropolitan centres. Outside the major Australian cities, most presentations to emergency departments are dealt with by 'non-specialist' doctors, often with limited specialist back up. Recruitment of suitably trained medical staff is increasingly difficult. There is increasing reliance on overseas trained doctors from widely varying backgrounds. In Canada and New Zealand, family medicine trained emergency medicine doctors are a significant proportion of the workforce in rural and regional emergency departments. AIM: To undertake a detailed investigation of the non-specialist emergency medicine doctors in Australia, and examine strategies to secure a more highly trained emergency medicine workforce for rural and regional Australia. METHODS: A survey was undertaken of 230 doctors working in 57 rural and regional Australian emergency departments. Consultations and interviews were held with 53 key clinicians, educators and administrators. RESULTS: There were no training or education standards for doctors working in smaller Australian emergency departments. There was considerable instability in the workforce with many planning to leave their current position or reduce their involvement in emergency medicine. The vast majority felt a need to undertake further emergency medicine training. There was little agreement among stakeholders as to how emergency medicine should be taught, or services delivered in rural and regional Australia. CONCLUSIONS: There is need in Australia to offer a specific postgraduate qualification in emergency medicine for doctors wishing to practise emergency medicine outside major city hospitals. Ideally, such a course would be largely taught in rural and regional hospitals and would contain additional elements relevant to rural practice. The Canadian and New Zealand emergency medicine qualifications may be useful models.


Asunto(s)
Actitud del Personal de Salud , Selección de Profesión , Educación de Postgrado en Medicina/normas , Medicina de Emergencia/educación , Servicios de Salud Rural , Australia , Escolaridad , Medicina de Emergencia/organización & administración , Necesidades y Demandas de Servicios de Salud , Humanos , Criterios de Admisión Escolar , Encuestas y Cuestionarios
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