RESUMEN
Various bovine ephemeral fever (BEF) vaccines were tested between 1982 and 1984 in 24 Queensland herds; neutralising antibody responses were monitored and six of the herds were closely observed following natural challenge with ephemeral fever. A vaccine regime of two consecutive vaccinations with attenuated virus combined with the adjuvant Quil A provided excellent protection against BEF for at least 12 months, whereas one vaccination with the Quil A vaccine or two vaccinations with vaccine containing the adjuvant aluminium hydroxide gel did not provide significant protection. Antibody responses were highest for the vaccine incorporating Quil A when it was given as two consecutive injections. There was an apparent relationship between neutralising antibody response and the level of protection.
Asunto(s)
Virus de la Fiebre Efímera Bovina/inmunología , Fiebre Efímera/inmunología , Vacunas Virales , Adyuvantes Inmunológicos , Animales , Anticuerpos Antivirales/biosíntesis , Anticuerpos Antivirales/sangre , Formación de Anticuerpos , Bovinos , Fiebre Efímera/prevención & control , Esquemas de Inmunización , Pruebas de Neutralización , Queensland , Seguridad , Vacunación , Vacunas Virales/administración & dosificación , Vacunas Virales/efectos adversosRESUMEN
Horses grazing manily Cenchrus ciliaris and/or Panicum maximum var. trichoglume pastures on over 30 properties in southern central Queensland developed lesions of osteodystrophia fibrosa. Horses on individual properties in coastal Queensland grazing Setaria anceps, Brachiaria mutica or Pennisetum clandestinum also developed the disease. Ill-thrift, lameness, and fibrous swellings of nasal bones, maxillae and mandibles were observed. Calcium and phosphorus levels of pasture were normal but all the above pasture species contained oxalates which were suspected of causing the disease.