The role of root zone soil moisture return on vegetation green-up: A comparison of two degrading permafrost sites.

The effects of permafrost degradation on ecological changes have attracted more and more attention, but the underlying interactive mechanisms are still not well understood. From a unique angle of view, this study focuses on the linkage between the freezing-induced root zone soil moisture return (SMR) and vegetation green-up along with climate warming and permafrost degradation. Using 7-year soil-weather monitoring data in the high-altitude and high-latitude permafrost regions, we investigated the changes of root zone SMR in two degrading permafrost sites. Results demonstrate that, as one important water source for vegetation green-up, the ratio of root zone SMR to the soil moisture storage after final thawed, Rsmr, could reach 22.8 % and 10.5 % at the two sites, respectively. In contrast to the negligible change at the high-latitude permafrost site, a rapid increase rate of 7.7 % per decade in Rsmr was found at the high-altitude permafrost site over the monitoring period of 2012-2018. Generally, vegetation green-up definitely benefited from the enrichment of soil moisture storage, but their sensitivities to climate warming and permafrost degradation were different at the two sites. The increase of Rsmr effectively buffered the shrinking trend of soil water availability of the root zone both over the pre-freezing and the green-up period at the high-altitude permafrost site. The changing role of root zone SMR might be threatened during the vegetation green-up in the longer future. Whereas, there would be no water shortage risk for the foreseeable future at the high-latitude permafrost site. Overall, this study emphasized the importance of SMR in enhancing soil water availability for vegetation green-up under the background of quick climate warming and permafrost degradation.

Immersion-Triggered Active Switch for Spin-Decoupled Meta-Optics Multi-Display.

Meta-optics exhibits many promising applications in various fields of optical displays, imaging, and information encryption. However, heading towards next-generation intelligent displays, its broad implementation is critically restricted by the lack of practical active tuning capability. Beyond the conventional electrical/optical/mechanical/thermal tuning methods, liquid immersion has recently emerged as a facile mechanism for active spectral tuning. To further conquer the challenge in achieving active complicated optical-field manipulation, here, an environment-compliant switch for meta-optics multi-display is originally proposed and experimentally realized via the liquid immersion tuning scheme. By designing the spin-decoupled phase array for left-/right-handed circular polarizations, it flexibly presents quad-fold independent-encoded phase distributions for different medium-relevant and polarization-controlled channels, thus enabling four switchable holographic images through immersion tuning. Such a proposed immersion tuning design is quite a straightforward approach for meta-optics holographic displays, enjoying full-spatial usage, design flexibility, and large-scale facile implementation. Overall, the proposed liquid immersion tuning strategy for a meta-optics multi-display would strongly benefit the practical applications in biochemical sensing, environment-adaptive displays, and information encryption.

On-chip asymmetric beam-steering for broadband visible light.

Artificial optical nanostructures including three-dimensional (3D) metamaterials and two-dimensional (2D) metasurfaces have shown overwhelming capability to control electromagnetic waves in desirable manners. However, the challenges of manufacturing a complex 3D bulk architecture or achieving nanoscale alignment between multilayers limit their practical applications, and they are unable to be used in on-chip integrated photonic devices. Therefore, the emerging dimensionality-reduction to on-chip metadevices would be of promising research value. Here, we propose a visible-frequency on-chip dual-layer design by cascading one-dimensional (1D) plasmonic metawires with metagratings, which can effectively manipulate surface plasmon polariton (SPP) wavefronts and exhibit on-chip asymmetric beam-steering functionality. Our 1D metawires consist of trapezoidal plasmonic nanoantennas and can enable broadband (460-700 nm) on-chip beam-deflection with a high conversion efficiency. The cascading plasmonic coupling between metawires/metagrating is further demonstrated with broadband asymmetric propagation performance, which is crucial for on-chip plasmonic device development. Finally, we study and theoretically verify a cascade system that integrates a dual-functional (convergent/divergent) lens for the forward/backward propagation, respectively. Compared with conventional free-space multilayer metasurfaces, on-chip 1D metawires enjoy single-time lithography processing and no alignment requirement for implementation in multifunctional devices. We believe that the proof-of-concept on-chip metawires study will pave a new, to the best of our knowledge, way for creating multifunctional photonic integrated devices and hold tremendous potential in realizing on-chip transformation optics, information processing, spectrometers, as well as optical sensors.

Dual-encryption freedom via a monolayer-nanotextured Janus metasurface in the broadband visible.

As an emerging category of two-faced 2D architecture, the Janus metasurface aims to explore another universal optical property, that is, the wavevector direction (k-direction), and to enable the asymmetric transmission between the opposite directional incidences. It exhibits significant potential in creating versatile multiplexing metasurfaces and an optical isolator in optical communication applications. However, most previous asymmetric functionality shows merely one-way functionality with the other-way simply muted or demands multilayered nanostructure fabrication and alignment. Hence, it remains a great challenge to make a monolayer-nanotextured Janus metasurface with dual-encryption freedom and conquering the difficulty for multilayer alignment and practical operation bandwidth. In this work, we have proposed and experimentally demonstrated a new strategy of a dual-encryption Janus metasurface design with a simple monolayer-nanotextured metasurface coupled with a commercialized film of the half-wave plate. Utilizing the hybridization from two independent geometrical dimensions of rectangular-antennas, our approach ingeniously transforms the polarization-multiplexing into the dual-directional channels. A series of calculations and experimental results demonstrate that our asymmetric approach simultaneously constructs completely independent imaging encryptions for both forward and backward directions. Additionally, our proposed approach becomes a practical scheme with broadband visible-frequency operation and great simplicity in design and nanofabrication. We believe the universal scheme could facilitate to increase the information encoding capacity and holographic multiplexing channels by expanding the illumination wavevector to the full-space (+/-), and it paves the route toward the potential applications in on-chip integration, telecommunications, encryption, information processing, and communication.

Angular Multiplexing Nanoprinting with Independent Amplitude Encryption Based on Visible-Frequency Metasurfaces.

Two-dimensional (2D) metasurfaces hold great promise to enable multiplexing and multifunctional optical devices due to their artificial freedom in design, device miniaturization, etc. Various multiplexing and multifunctional metasurfaces have been extensively studied, including polarization multiplexing, wavelength multiplexing, and orbit angular momentum (OAM) multiplexing. However, due to the lack of angular encoding freedom, angular multiplexing switchable nanoprinting has rarely been studied or demonstrated yet to the best of our knowledge. Here, we realize angular multiplexing switchable nanoprinting functionality with independent amplitude encryption based on visible-frequency metasurfaces. By screening a large number of structural designs and breaking the angular correlation, we eventually obtain optimal metasurface designs to realize dual-channel arbitrary image encryption. Furthermore, we illustrate that the proposed scheme would serve as an optical information concealment/retrieval strategy by combining the structural color and amplitude modulation. Overall, we believe that angular multiplexing metasurfaces would easily find promising applications, including optical information encryption/concealment, multifunctional switchable devices, and advanced eyeglass-free three-dimensional (3D) stereoscopic displays.

3D Meta-Prisms for Versatile Beam Steering by Hybridizing Plasmonic and Diffractive Effect in the Broadband Visible Regime.

As two independent optical sub-fields, diffraction optics and plasmonics both have been used for wavefront shaping and beam steering. However, the two separate concepts have always been developing as two parallel directions, which have not met for studying their structural hybridization to discover new potentials. For instance of the flat metasurfaces, even though the geometric parameters including shape, size, and periodicity have been studied, it remains mostly unexplored for the 3D spatial height variation. Here, a new type of all-metallic 3D meta-prism is proposed and experimentally demonstrated by hybridizing the localized surface plasmonic resonances (LSPR) and the blazed grating diffraction, which enables strong polarization-dependent behaviors to steer broadband visible light to drastically inverse directions. The nanofabrication of 3D meta-prism is achieved by nanostencil lithography with electron-beam evaporation. Such meta-prism could also enable to split different visible light (green, blue, and red) with high-efficiency contrast (≈10). By the mirror-symmetry arrangement, a multifunctional surface is demonstrated with polarization-/wavelength-multiplexing wavefront-shaping functions (concave, convex, or flat mirror). This unique 3D meta-prism enjoys great simplicity and versatility in broadband beam steering through the incorporation of plasmonic and diffractive effects and can be utilized in various applications including dichroic-prism splitters, multifunctional meta-mirrors, etc.

Polarization-insensitive broadband visible-light steering with tunable direction enabled by scalable plasmonics meta-gratings.

As an emerging field in the discipline of optics, plasmonics and metasurfaces have been demonstrated to enable a new degree of freedom to manipulate light for arbitrary beam steering, spectral splitting as well as precise wavefront shaping. However, it has been mostly studied in parallel with the field of diffractive optics, and awaits the unveiling of how the hybridizations between plasmonic effect and diffraction effect interact and impact. Here, we have theoretically proposed a new type of polarization-insensitive meta-grating structure across the broadband visible regime. The structure design combines the width gradient (critical resonant length) from a trapezoid-nanoantenna with the height gradient from a blazed grating profile. The hybridized meta-grating creates both plasmonic effect and grating effect, which enables all the optical incident photons to be directed to the same orientation regardless of the light polarization. As we know, both metasurfaces and diffractive optical elements (such as gratings) are, more often than not, quite sensitive to the incident light polarization. Moreover, if placing our meta-grating on a flexible/stretchable substrate (such as polydimethylsiloxane), the outgoing angle can be effectively adjusted by tuning the period or density of meta-grating arrays. Such meta-grating architectures can be potentially manufactured by existing photolithography and nanoimprint techniques, and can easily find a wide range of practical polarization-insensitive applications, including broadband deflector and emitter, tunable display and imaging device, high signal-to-noise ratio spectrometer, polarization-insensitive plasmonic coupler, etc.

Circular RNA 0001313 Knockdown Suppresses Non-Small Cell Lung Cancer Cell Proliferation and Invasion via the microRNA-452/HMGB3/ERK/MAPK Axis.

BACKGROUND: Non-small cell lung cancer (NSCLC) seriously endangers human health. Circular RNAs (circRNAs) regulate diverse types of cancers, including NSCLC. This study investigated the possible mechanism of circ0001313 in NSCLC. MATERIALS AND METHODS: Circ0001313 expression in NSCLC tissues was measured, and its correlation with clinicopathological features was analyzed. The binding relationships among circ0001313, microRNA (miR)-452 and HMGB3 were tested. The gain and loss of functions were performed to examine NSCLC cell malignant behaviors. After HMGB3 overexpression, ERK/MAPK pathway-related protein levels were detected. Subsequently, the rescue experiment was further performed using an ERK/MAPK pathway inhibitor PD98059. RESULTS: Abnormally elevated circ0001313 and decreased miR-452 in NSCLC cells were observed. Circ0001313 silencing or miR-452 overexpression significantly reduced NSCLC cell proliferation and invasion. Circ0001313 competitively bound to miR-452 to upregulate HMGB3, thus promoting NSCLC cell growth. HMGB3 overexpression activated the ERK/MAPK pathway to contribute to NSCLC development. CONCLUSION: We highlighted that silencing of circ0001313 blunted the ERK/MAPK pathway via the miR-452/HMGB3 axis, thereby inhibiting NSCLC cell proliferation and invasion.

On-chip metalenses based on one-dimensional gradient trench in the broadband visible.

Metasurfaces are composed of flat, ultrathin subwavelength nanoantennas with strong capability in manipulating light propagation by modulations on its phase, amplitude, and polarization. For instance, the invention of two-dimensional (2D) metalenses has enabled light focusing and imaging in three-dimensional (3D) free space with miniaturized thickness and device size at a planar surface. However, such inherent form of 2D arrays and focusing functionality at 3D optical free-space limits the degree of freedom for light propagation and manipulation along a 2D planar surface and eventually the possibility of on-chip photonic system integration. Here, we theoretically study and demonstrate a new type of planar on-chip metalens, which enables light focusing and strong localization at a 2D surface. The planar on-chip architecture design is based on the one-dimensional (1D) length or width gradient trench metalens (GTM), which could yield the elaborately engineered phase shift for propagating light within the on-chip waveguide at the visible wavelength of 500 nm. By generating 1D phase arrangement at the nanoscale, a miniature on-chip metalens with ∼3×0.5µm dimension could achieve light focusing on a 2D waveguide surface with the flexibility to design scalable focal lengths and ultra-high numerical aperture of up to ∼0.99. Additionally, GTM metalens designs could also exhibit overlapped high depth-of-focus, which consequently could behave as achromatic-like lensing at the selected focal plane. Furthermore, we manifest that the focusing functionality can also be subject to dynamically tuning and switching on-and-off with TE/TM polarization change or waveguide index alteration. We believe this new form of on-chip 1D metalens holds potential applications including on-chip light manipulation functionality of focusing and diverging, optical on-chip sensing, next-generation on-chip optical communication, signal processing as well as imaging devices, etc.

Effect of Qinbai Qingfei Concentrated Pellets on substance P and neutral endopeptidase of rats with post-infectious cough.

BACKGROUND: In recent years, it has been reported that Qinbai Qingfei Concentrated Pellet (QQCP) has the effect of relieving cough and reducing sputum. However, the therapeutic potentials of QQCP on post-infectious cough (PIC) rat models has not been elucidated. So the current study was aimed to scientifically validate the efficacy of QQCP in post infectious cough. METHODS: All rats were exposed to sawdust and cigarette smokes for 10 days, and intratracheal lipopolysaccharide (LPS) and capsaicin aerosols. Rats were treated with QQCP at dose of 80, 160, 320 mg/kg. Cough frequency was monitored twice a day for 10 days after drug administration. Inflammatory cell infiltration was determined by ELISA. Meanwhile, the histopathology of lung tissue and bronchus in rats were evaluated by hematoxylin-eosin staining (H&E). Neurogenetic inflammation were measured by ELISA and qRT-PCR. RESULTS: QQCP dose-dependently decreased the cough frequency and the release of pro-inflammatory cytokines TNF-α, IL-1ß, IL-6 and IL-8, but exerted the opposite effects on the secretion of anti-inflammatory cytokines IL-10 and IL-13 in BALF and serum of PIC rats. The oxidative burden was effectively ameliorated in QQCP-treated PIC rats as there were declines in Malondialdehyde (MDA) content and increases in Superoxide dismutase (SOD) activity in the serum and lung tissue. In addition, QQCP blocked inflammatory cell infiltration into the lung as evidenced by the reduced number of total leukocytes and the portion of neutrophils in the broncho - alveolar lavage fluid (BALF) as well as the alleviated lung damage. Furthermore, QQCP considerable reversed the neurogenetic inflammation caused by PIC through elevating neutral endopeptidase (NEP) activity and reducing Substance P (SP) and Calcitonin gene related peptide (CGRP) expression in BALF, serum and lung tissue. CONCLUSIONS: Our study indicated that QQCP demonstrated a protective role of PIC and may be a potential therapeutic target of PIC.

High-NA achromatic diffractive lensing for arbitrary dual-wavelengths enabled by hybridized metal-insulator-metal cavities.

A new type of diffractive lens based on hybridized Fabry-Perot (FP) cavities with high-NA and achromatic features for arbitrary dual-wavelengths is theoretically proposed and demonstrated. We utilize the subwavelength-scale metal-insulator-metal nanocavity to form a Fresnel zone plate (MIM-FZP) that benefits from both spectral selectivity and high numerical aperture (NA > 0.9) to enable lensing functionality. By taking advantage of the different transmission orders from MIM, any arbitrary dual-wavelength achromatic focusing design is achieved. Using this approach, we merge two independent MIM-FZP designs and realize achromatic focusing performance at the selected dual-wavelength of 400/600 nm. Furthermore, the achromatic lens also exhibits a crucial potential for dynamically tuning of the operation wavelengths and focusing lengths as actively scaling the core layer thickness of MIM. The unique MIM-FZP design can be practically fabricated using a grayscale lithography technique. We believe such high-NA and achromatic optical devices enjoy great simplicity for structural design and can easily find applications including high-resolution imaging, new-generation integrated optoelectronic devices, confocal collimation, and achromatic lens, etc.

Isotopic constraints on water balance of tundra lakes and watersheds affected by permafrost degradation, Mackenzie Delta region, Northwest Territories, Canada.

Widespread permafrost degradation in Canada's western Arctic has led to formation of shoreline retrogressive thaw slumps (SRTS), a process influential in modifying water and biogeochemical balances of tundra lakes. To investigate hydrological effects of SRTS, water sampling campaigns were conducted in 2004, 2005, and 2008 for paired lakes (undisturbed vs SRTS) in the upland region adjacent to the Mackenzie Delta, Northwest Territories, Canada. An isotope mass balance model to estimate evaporation/inflow, precipitation/inflow, water yield, and runoff ratio was developed incorporating seasonal evaporative drawdown effects and a mixing model to simulate gradients in marine-continental atmospheric moisture. Site-specific water balance results revealed systematically higher evaporation/inflow and precipitation/inflow for lakes with active SRTS compared to undisturbed lakes, and typically higher ratios of these indicators associated with stabilized versus active SRTS. Water yields were higher for active SRTS sites compared to undisturbed and stabilized SRTS sites, suggesting that slumping is an initial but not a sustained source of water delivery to lakes. Catchments with wildfire history were found to have lower water yields, attributed to reduced permafrost influence on runoff generation. Conceptually, we define a permafrost thaw trajectory whereby undisturbed sites, active SRTS, stabilized SRTS, and ancient SRTS represent progressive stages of permafrost thaw. We postulate that release of additional runoff is mainly due to permafrost thaw in active SRTS, which also promotes lake expansion, talik formation, and subsurface connectivity. Eventual stabilization of slumps and reduced runoff is expected once permafrost thaw sources are exhausted, at which time lakes may become more reliant on replenishment by direct precipitation. The effect of snow catch in slumps appears to be subordinate to permafrost thaw sources based on eventual decline in runoff once thaw slumps stabilize. Improved, site-specific hydrologic understanding is expected to assist with ongoing research into carbon cycling and biogeochemical feedbacks in the region.

Visible-frequency meta-gratings for light steering, beam splitting and absorption tunable functionality.

Diffractive grating and plasmonic metasurface have always been developing as two parallel optical domains, which have not met for studying their hybridization to discover new applications and potentials. Here, we proposed a novel meta-grating design, which hybridizes the metasurface interfacial gradient with the blazed grating profile. The unique architecture takes advantage of both grating effect and plasmonic resonances with minimum cross-coupling, thus leading to the polarization-selective behaviors to steer different polarized light to drastically inverse directions (> 90°). Furthermore, the hybridized surface also exhibits angle-dependent broadband absorptive tunability (∼ 5% - 86%) by migrating the strong blazed order and plasmonic order at the far field. We believe that the integrated meta-grating device would suggest various potential applications including polarization beam splitters, high signal-to-noise ratio (SNR) optical spectrometer, high-efficiency plasmonic couplers and filter, etc.

Using stable isotopes paired with tritium analysis to assess thermokarst lake water balances in the Source Area of the Yellow River, northeastern Qinghai-Tibet Plateau, China.

A spatially distributed network of thermokarst lakes undergoing significant environmental changes was sampled in 2014 and 2016 to develop a comprehensive understanding of lake water balances in lakes across a gradient of frozen ground conditions. Frozen ground ranges from seasonally frozen ground (SFG) to sporadic discontinuous permafrost (SDP) to extensive discontinuous permafrost (EDP), and is representative of complex conditions in the Source Area of the Yellow River, northeastern part of Qinghai-Tibet Plateau. Radioactive and stable water isotopes in reference lakes (non-thaw lakes), thermokarst lakes, precipitation, wetlands, ground ice and supra-permafrost groundwater are analyzed to characterize systematic variations and to assess lake water balances using stable isotope mass balance (IMB). IMB, paired with analysis of tritium decay gradients, is shown to be a valid approach for detecting short-term shifts in lake water balance, which allows evaluation of the proportion of precipitation-derived versus permafrost-derived water inputs to lakes. All lakes except EDP thaw lakes are evaporation-dominated (E/I > 0.5). Negative water balances occurred most frequently in reference lakes due to hydrological connectivity with rivers. Precipitation-derived water inputs result in positive water balances in SFG and SDP thermokarst lakes, but negative-trending water balances are found in SDP thermokarst lakes due to substantial reduction in water yield. Increasing contributions from thawing permafrost in EDP thermokarst lakes result in strong positive water balance. Permafrost degradation may also lead to the changes in hydrological connectivity between precipitation and wetlands or thermokarst lakes. Based on these findings, a conceptual model of the hydrological evolution of thermokarst lakes under the influence of permafrost degradation is proposed.

Use of 10Be isotope to predict landscape development in the source area of the Yellow River (SAYR), northeastern Qinghai-Tibet Plateau.

The magnitude of soil and sediment erosion and accumulation processes can profoundly affect landscape development and hamper efficient management of natural resources. Consequently, estimating the rates and causes of these processes is essential, particularly in remote regions, for prediction of changes in landform and river evolution and protection of local ecosystem. We here present the results of a soil and sediment erosion investigation in the Source Area of the Yellow River (SAYR), northeast Qinghai-Tibet Plateau based on a combined analysis of 10Be cosmogenic isotope and Soil and Water Assessment Tool (SWAT) simulation modelling. The data reveal variable soil erosion trends that range between 103 and 830 t km-2 a-1. The low values occur in the western part of the basin that are associated with low sediment yield, while the high values appear in the dominant sediment export part of the basin along the main stream of the Yellow River in the east. Generally, soil and sediment accumulation is characterized by high 10Be concentration in the western part and the northwest of Ngöring Lake. The style of landform development by the erosion/accumulation processes is closely linked to the distribution and degradation extent of the permafrost in the study region. Soil surface erosion increases with more permafrost degradation from the western to the eastern part of the basin, and surface soil particles are dominantly removed from the surface rather than deeper layers.

Evaluation of groundwater discharge into surface water by using Radon-222 in the Source Area of the Yellow River, Qinghai-Tibet Plateau.

Understanding hydrological processes in the Source Area of the Yellow River (SAYR), Qinghai-Tibet Plateau, is vital for protection and management of groundwater and surface water resources in the region. In situ water measurements of exchange rates between surface water and groundwater are, however, hard to conduct because of the harsh natural conditions of the SAYR. We here present an indirect method using in situ 222Rn measurements to estimate groundwater discharge into rivers and lakes in the SAYR. 222Rn was measured in rivers, lakes, groundwater and springs during three sampling periods (2014-2016), and the results indicate large variability in the concentration of the isotope. The data also indicate decreasing 222Rn trends in groundwater in the cold season (the Feb-2015 sampling period) which may be linked to frequency of capturing 222Rn in the frozen ground caused by geocryogenic processes. In addition, permafrost spatial extent and freeze-thaw processes have strongly affected the hydrological conditions in the region.