1.
J Headache Pain
; 25(1): 32, 2024 Mar 07.
Artículo
en Inglés
| MEDLINE
| ID: mdl-38454380
RESUMEN
BACKGROUND: New guidelines for cluster headache clinical trials were recently published. We welcome these new guidelines and raise additional considerations in trial methodologies. MAIN BODY: We present non-inferiority trials to overcome ethical issues with placebo use, and additionally discuss issues with trial recruitment. CONCLUSIONS: We highlight some possible issues and solutions to be considered with the recently published cluster headache trial guidelines.