1.
Org Biomol Chem
; 20(33): 6566-6570, 2022 08 24.
Artículo
en Inglés
| MEDLINE
| ID: mdl-35903979
RESUMEN
An efficient potassium persulfate-mediated radical addition of allenamides with diselenides was developed to create a workable route to 1,2-diselenide products. The reaction tolerates a wide spectrum of functional groups to deliver the products in good to excellent yields. Mechanistic investigations including a calculation study indicated that the radical cascade proceeds through a vinyl radical intermediate, which is formed via a selenium radical added to the terminal CîC double bond of allenamides.