RESUMEN
Surveys are quick and easy to produce. This paper outlines some of the many problems that should be anticipated.
Asunto(s)
Encuestas y Cuestionarios , HumanosRESUMEN
Surveys are quick and easy to produce. This paper outlines some of the many problems that should be anticipated.
RESUMEN
The essential principles of statistics as applied to surveys, studies, sampling, epidemiology, screening, and trials are described and explained.
Asunto(s)
Estadística como Asunto , Ensayos Clínicos como Asunto , Epidemiología , Humanos , Tamizaje MasivoRESUMEN
All animal life on earth is thought to have a common origin and have common genetic mechanisms. Evolution has enabled differentiation of species. Pathogens likewise have evolved within various species and mostly come to a settled dynamic equilibrium such that co-existence results (pathogens ideally should not kill their hosts). Problems arise when pathogens jump species because the new host had not developed any resistance. These infections from related species are known as zoonoses. COVID-19 is the latest example of a virus entering another species but HIV (and various strains of influenza) were previous examples. HIV entered the human population from monkeys in Africa. These two papers outline the underlying principle of HIV and the differing epidemiologies in Africa, the USA and in Edinburgh. The underlying immunosuppression of HIV in Africa was initially hidden behind common infections and HIV first came to world awareness in focal areas of the USA as a disease seemingly limited to gay males. The epidemic of intravenous drug abuse in Edinburgh was associated with overlapping epidemics of bloodborne viruses like hepatitis B, hepatitis C and HIV.
Asunto(s)
Coinfección/virología , Infecciones por VIH/fisiopatología , Hepatitis B/fisiopatología , Hepatitis C/fisiopatología , Animales , Brotes de Enfermedades , Infecciones por VIH/genética , Infecciones por VIH/virología , VIH-1/genética , VIH-1/patogenicidad , Hepatitis B/genética , Hepatitis C/genética , Humanos , Compartición de Agujas/estadística & datos numéricos , Filogenia , Abuso de Sustancias por Vía Intravenosa/epidemiología , ZoonosisRESUMEN
All animal life on earth is thought to have a common origin and have common genetic mechanisms. Evolution has enabled differentiation of species. Pathogens likewise have evolved within various species and mostly come to a settled dynamic equilibrium such that co-existence results (pathogens ideally should not kill their hosts). Problems arise when pathogens jump species because the new host had not developed any resistance. These infections from related species are known as zoonoses. COVID-19 is the latest example of a virus entering another species but HIV (and various strains of influenza) were previous examples.