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Am Surg ; 82(11): 1068-1072, 2016 Nov 01.
Artículo en Inglés | MEDLINE | ID: mdl-28206933

RESUMEN

The treatment of complex wounds is commonplace for plastic surgeons. Standard management is debridement of infected and devitalized tissue and systemic antibiotic therapy. In cases where vital structures are exposed within the wound, coverage is obtained with the use of vascularized tissue using both muscle and fasciocutaneous flaps. The use of nondissolving polymethylmethacrylate and absorbable antibiotic-impregnated beads has been shown to deliver high concentrations of antibiotics with low systemic levels of the same antibiotic. We present a multicenter retrospective review of all cases that used absorbable antibiotic-impregnated beads for complex wound management from 2003 to 2013. A total of 104 cases were investigated, flap coverage was used in 97 cases (93.3%). Overall, 15 patients (14.4%) required reoperation with the highest groups involving orthopedic wounds and sternal wounds. The advantages of using absorbable antibiotic-impregnated beads in complex infected wounds have been demonstrated with minimal disadvantages. The utilization of these beads is expanding to a variety of complex infectious wounds requiring high concentrations of local antibiotics.


Asunto(s)
Antibacterianos/administración & dosificación , Fracturas Abiertas/cirugía , Mediastinitis/cirugía , Microesferas , Traumatismos de los Tejidos Blandos/cirugía , Colgajos Quirúrgicos/trasplante , Infección de la Herida Quirúrgica/cirugía , Carcinoma de Células Escamosas/terapia , Humanos , Neoplasias Hipofaríngeas/terapia , Masculino , Persona de Mediana Edad , Polimetil Metacrilato/administración & dosificación , Reoperación , Estudios Retrospectivos , Traumatismos de los Tejidos Blandos/patología , Infección de la Herida Quirúrgica/patología
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