1.
Bioorg Med Chem Lett
; 27(2): 143-146, 2017 01 15.
Artículo
en Inglés
| MEDLINE
| ID: mdl-27979595
RESUMEN
The inhibition of aldosterone synthase (CYP11B2) may be an effective treatment of hypertension and heart failure, among other ailments. Previously reported benzimidazole CYP11B2 inhibitors led the way for bioisosteric imidazopyridines that are both potent and selective over CYP11B1.