Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 26
Filtrar
1.
Clin J Sport Med ; 32(2): e145-e150, 2022 03 01.
Artículo en Inglés | MEDLINE | ID: mdl-33852439

RESUMEN

OBJECTIVE: The purpose of this study was to investigate injury occurrence sustained by collegiate rodeo athletes during practice and competition. DESIGN: Descriptive epidemiology. SETTING: Eleven National Intercollegiate Rodeo Association member institutions across the United States. PARTICIPANTS: Participants included 264 male and female college rodeo athletes. Athletic trainers (ATs) from each institution reported injury and exposure data using the National Collegiate Athletic Association Injury Surveillance Program. INTERVENTIONS: Institutional ATs reported athlete exposures (AEs) and injuries that occurred from collegiate rodeo practices and competitions. MAIN OUTCOME MEASURE: Injury and AEs from practices and competitions for one college rodeo season were analyzed. Injury rates and ratios were calculated for non-time loss (NTL) and time loss (TL) with 95% confidence intervals (CI). RESULTS: Data revealed a higher proportion of TL than NTL injuries [2.47 vs 1.77 per 1000 AE; injury rate ratios (IRRs) = 1.39; 95% CI: 0.93-2.08]. There was a higher injury rate during competition as compared with practice (10.98 vs 3.09 per 1000 AE; IRR = 3.56; 95% CI: 2.36-5.35), but more injuries were reported in practice (62.2%). CONCLUSIONS: Although the injury rate during rodeo competition was significantly higher than during practice in this study, a greater number of injuries were reported during practice. This indicates all college rodeo athletes can potentially benefit from available medical care.


Asunto(s)
Traumatismos en Atletas , Conmoción Encefálica , Atletas , Traumatismos en Atletas/epidemiología , Conmoción Encefálica/epidemiología , Femenino , Humanos , Incidencia , Masculino , Instituciones Académicas , Estudiantes , Estados Unidos/epidemiología , Universidades
2.
Int J Exerc Sci ; 13(4): 539-553, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-32509124

RESUMEN

Post-activation potentiation (PAP) is a phenomenon characterized by improved muscle performance based on the previous contractile activity of the muscle. The purpose of this study was to determine the effect of different potentiating stimuli on jump and sprint performance in 13 resistance trained, college-aged men and women. After determining back squat 1 repetition max, subjects returned for testing on separate days to complete one of four interventions (dynamic resistance, weighted plyometric, isometric, or control) in a randomized order. A standardized warmup was performed, followed by a baseline countermovement jump (CMJ) and 20m sprint. Following warm-up and baseline measurements, subjects performed one of the four experimental conditions. CMJ and 20m sprint measurements were completed again at 20-seconds, 4, 8, 12, 16, and 20-minutes. Results revealed significantly faster 0-20m sprint times (p < .05) at the 4, 8, 12, 16, and 20-minute time points compared to baseline and 20-second time points. Significantly faster 0-20m sprint times (p < .05) were also shown for the squat intervention compared to control at 4-minutes, the plyometric and squat intervention compared to control at 8-minutes, the isometric intervention compared to control at 12 and 16-minutes, and the isometric intervention compared to the squat at 20-minutes. These findings indicate that while all PAP stimuli utilized can be effective at improving sprint performance, specific optimal time points may exist.

3.
Appl Physiol Nutr Metab ; 44(7): 791-795, 2019 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-30608872

RESUMEN

The purpose of this study was to investigate the effect of 6 weeks of oral Echinacea purpurea supplementation on serum erythropoietin (EPO) and erythropoietic status. Twenty-four males (mean ± SE; age = 25.2 ± 1.4 years, height = 178.1 ± 1.4 cm, body mass = 78.1 ± 1.6 kg, body fat = 12.7 ± 0.9%, maximal oxygen uptake = 52.9 ± 0.9 mL·kg-1·min-1) were randomly grouped using a matched-pair, double-blind design and self-administered 8000 mg·day-1 of either E. purpurea (n = 12) or placebo (n = 12) for 42 consecutive days. Blood samples were collected prior to supplementation (day 0) and every 2 weeks during the supplementation period (days 14, 28, and 42) and were analyzed for EPO, red blood cell count, hemoglobin concentration, hematocrit, mean corpuscular volume, and mean corpuscular hemoglobin concentration. Separate 2 × 4 (group × time) factorial ANOVA with repeated measures on time were used to determine statistical differences with significance set at p ≤ 0.05. There were no significant interaction, group, or time effects observed for EPO or erythropoietic status markers for any of the measurement points (p ≤ 0.05). The present study indicated that 6 weeks of oral E. purpurea supplementation in recreationally active males with above average aerobic fitness did not enhance EPO or erythropoietic status. These findings are in contrast with previous reports of E. purpurea supplementation in untrained participants with average fitness levels, but consistent with observations in trained endurance athletes.


Asunto(s)
Aerobiosis/fisiología , Suplementos Dietéticos , Echinacea/química , Eritropoyesis/efectos de los fármacos , Eritropoyetina/sangre , Aptitud Física/fisiología , Adulto , Umbral Anaerobio/efectos de los fármacos , Método Doble Ciego , Recuento de Eritrocitos , Índices de Eritrocitos , Hematócrito , Hemoglobinas/análisis , Humanos , Masculino , Adulto Joven
4.
J Strength Cond Res ; 32(10): 2743-2749, 2018 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-29112051

RESUMEN

Whitehead, MT, Scheett, TP, McGuigan, MR, and Martin, AV. A comparison of the effects of short-term plyometric and resistance training on lower-body muscular performance. J Strength Cond Res 32(10): 2743-2749, 2018-The purpose of this study was to compare effects of short-term plyometric and resistance training on lower-body muscular performance. A convenience sample of 30 male subjects aged 21.3 ± 1.8 years (height, 177.3 ± 9.4 cm; mass, 80.0 ± 2.6 kg; body fat, 16.1 ± 1.2%) participated in this investigation. Participants were grouped, and they participated in progressive plyometric (PLT) or resistance training (SRT) twice per week for 8 consecutive weeks or a control (CNT) group that did not participate in any training. Performance tests were administered before and after the training period, and it included measures of high-speed muscular strength (standing long jump, vertical jump), low-speed muscular strength (1-repetition maximal back squat), running speed (20-m sprint), and running agility (505 agility test). Analysis of variance followed by post hoc analyses was performed to determine significant differences between the groups. Significance set at p ≤ 0.05 for all analyses. Significant improvements were observed in the PLT group for standing long jump, vertical jump, and 1-repetition maximal back squat compared with the CNT group and for vertical jump as compared with the SRT group. Significant improvements were observed in the SRT group 1-repetition maximal back squat compared with the CNT group. There were no differences observed between any of the groups for the 20-m sprint or the 505 agility test after the training. These data indicate that 8 weeks of progressive plyometric training results in improvements in parameters of high-speed and low-speed muscular strength with no appreciable change in speed or agility. Additionally, the improvement in low-speed muscular strength observed from 8 weeks of progressive plyometric training was comparable to the results observed from 8 weeks of progressive strength training.


Asunto(s)
Rendimiento Atlético/fisiología , Ejercicio Pliométrico/métodos , Entrenamiento de Fuerza/métodos , Humanos , Masculino , Fuerza Muscular , Carrera , Adulto Joven
5.
J Allied Health ; 42(2): 79-83, 2013.
Artículo en Inglés | MEDLINE | ID: mdl-23752234

RESUMEN

This study investigated a pretest strategy that identified physical therapist assistant (PTA) students who were at risk of failure on the National Physical Therapy Examination (NPTE). Program assessment data from five cohorts of PTA students (2005-2009) were used to develop a stepwise multiple regression formula that predicted first-time NPTE licensure scores. Data used included the Nelson-Denny Reading Test, grades from eight core courses, grade point average upon admission to the program, and scores from three mock NPTE exams given during the program. Pearson correlation coefficients were calculated between each of the 15 variables and NPTE scores. Stepwise multiple regression analysis was performed using data collected at the ends of the first, second, and third (final) semesters of the program. Data from the class of 2010 were then used to validate the formula. The end-of-program formula accounted for the greatest variance (57%) in predicted scores. Those students scoring below a predicted scaled score of 620 were identified to be at risk of failure of the licensure exam. These students were counseled, and a remedial plan was developed based on regression predictions prior to them sitting for the licensure exam.


Asunto(s)
Evaluación Educacional/métodos , Concesión de Licencias , Asistentes de Fisioterapeutas/educación , Especialidad de Fisioterapia/educación , Adulto , Consejo , Femenino , Humanos , Masculino , Persona de Mediana Edad , Valor Predictivo de las Pruebas , Análisis de Regresión , Estudios Retrospectivos , Medición de Riesgo , Estados Unidos
6.
Clin Endocrinol (Oxf) ; 78(2): 297-302, 2013 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-22775481

RESUMEN

OBJECTIVE: To determine the effects of tibolone or oestradiol (E(2) )/norethisterone acetate (NETA) hormone replacement therapy on glucose and insulin metabolism in postmenopausal women. DESIGN: Single-centre double-blind placebo-controlled randomized clinical trial. SUBJECTS/METHODS: We randomized 105 healthy postmenopausal women to tibolone 2·5 mg daily, continuous combined oral E(2) 2 mg/NETA 1 mg daily or placebo over a 2-year study. We performed intravenous glucose tolerance tests (IVGTT) with measurements of plasma glucose, insulin and C-peptide concentrations and the IVGTT glucose elimination rate, k. Mathematical modelling was performed to determine measures of insulin sensitivity, S(i) , pancreatic insulin secretion and hepatic and plasma insulin elimination. RESULTS: Tibolone decreased S(i) to 53-63% and k to 72-79% of baseline values but increased IVGTT phase 2 C-peptide concentrations 1·6-1·8-fold and pancreatic insulin secretion 2·2-2·4-fold, so overall IVGTT glucose concentrations were unaffected. Similar, but for k, significantly smaller changes in insulin and C-peptide secretion were seen with E(2) /NETA, also with no effect on overall IVGTT glucose concentrations. CONCLUSIONS: Tibolone reduces insulin sensitivity. Healthy postmenopausal women seem able to compensate for this and maintain normal postload glucose concentrations, but it may not be advisable to prescribe tibolone to women with, or at increased risk for, diabetes.


Asunto(s)
Estradiol/farmacología , Glucosa/metabolismo , Insulina/metabolismo , Noretindrona/farmacología , Norpregnenos/farmacología , Anciano , Glucemia , Péptido C/sangre , Anticonceptivos Sintéticos Orales/administración & dosificación , Anticonceptivos Sintéticos Orales/farmacología , Estradiol/administración & dosificación , Moduladores de los Receptores de Estrógeno/administración & dosificación , Moduladores de los Receptores de Estrógeno/farmacología , Estrógenos/administración & dosificación , Estrógenos/farmacología , Femenino , Humanos , Insulina/sangre , Resistencia a la Insulina , Persona de Mediana Edad , Noretindrona/administración & dosificación , Norpregnenos/administración & dosificación
7.
Int J Sports Phys Ther ; 7(4): 365-71, 2012 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-22893856

RESUMEN

INTRODUCTION/PURPOSE: Shoulder dysfunction and injury are common in throwing athletes. Loss of internal rotation has been correlated to shoulder pathologies. The purpose of this study was to assess the effects of a stretching protocol on passive internal rotation. The purpose of this study was assess the effects of a stretching protocol on passive internal rotation motion in the throwing shoulders of collegiate baseball players. STUDY DESIGN: Pre-Post, intervention, using a within subjects comparison of a convenience sample. METHODS: Glenohumeral internal rotation and external rotation of the throwing and non-throwing shoulders of NCAA Division I baseball players were measured using a universal goniometer. Determinations were made as to the degree of Glenohumeral Internal Rotation Deficit (GIRD) in the throwing shoulder. A daily (5 days per week), 12-week posterior capsule stretching program was administered. Post-stretching internal rotation and external rotation measures were again obtained. The coaches and athletic trainers of the included team monitored the players for shoulder injuries and innings of training/competition lost due to shoulder injuries during the 12 week intervention. RESULTS: A significant increase in range of motion was found for dominant arm internal rotation (IR) and total range of motion (TOT) following the stretching program. No statistically significant improvement in range of motion was found for external rotation (ER), non-throwing arm internal rotation (NDIR), non-throwing arm external rotation (NDER), and non-throwing arm total motion (NDTOT). CONCLUSIONS: Implementation of a posterior capsule stretching program may be helpful to facilitate increased passive internal rotation range of motion at the glenohumeral joint. Further research should be performed using a control group not receiving the stretching program in order to more completely establish the impact of stretching on measures of passive glenohumeral range of motion. LEVEL OF EVIDENCE: 1b.

8.
J Strength Cond Res ; 26(7): 1928-33, 2012 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-22728943

RESUMEN

The purpose of this investigation was to determine the effects of 4 weeks of oral Echinacea (ECH) supplementation on erythropoietin (EPO), red blood cell (RBC) count, running economy (RE), and VO2max. Twenty-four men aged 24.9 ± 4.2 years, height 178.9 ± 7.9 cm, weight 87.9 ± 14.6 kg, body fat 19.3 ± 6.5% were grouped using a double-blind design and self-administered an 8,000-mg·d(-1) dosage of either ECH or placebo (PLA) in 5 × 400 mg × 4 times per day for 28 days. Blood samples were collected and analyzed for RBCs and EPO using automated flow cytometery and enzyme-linked immunosorbent assay. Maximal graded exercise tests (GXTs) were administered to measure VO2max, RE, and heart-rate responses. Analysis of variance was used to determine statistically significant differences (P ≤ 0.05). The EPO increased significantly in ECH at 7 days (ECH: 15.75 ± 0.64, PLA: 10.01 ± 0.73 mU·ml(-1)), 14 days (ECH: 18.88 ± 0.71, PLA: 11.02 ± 0.69 mU·ml(-1)), and 21 days (ECH: 16.06 ± 0.55, PLA: 9.20 ± 0.55 mU·ml(-1)). VO2max increased significantly in ECH (ECH: 1.47 ± 1.28, PLA: -0.13 ± 0.52%). Running economy improved significantly in ECH as indicated by a decrease in submaximal VO2max during the first 2 stages of the GXT (stage 1: ECH -1.50 ± 1.21, PLA 0.60 ± 1.95%; stage 2: ECH -1.67 ± 1.43, PLA 0.01 ± 1.03%). These data suggest that ECH supplementation results in significant increases in EPO, VO2max, and running economy.


Asunto(s)
Suplementos Dietéticos , Echinacea , Consumo de Oxígeno/efectos de los fármacos , Preparaciones de Plantas/administración & dosificación , Carrera/fisiología , Adulto , Análisis de Varianza , Método Doble Ciego , Recuento de Eritrocitos , Eritropoyetina/sangre , Prueba de Esfuerzo , Frecuencia Cardíaca/efectos de los fármacos , Humanos , Masculino , Adulto Joven
10.
Maturitas ; 61(1-2): 95-106, 2008.
Artículo en Inglés | MEDLINE | ID: mdl-19434883

RESUMEN

The importance of distinguishing climacteric symptoms from other psychological and somatic complaints has been repeatedly stressed, but as yet no detailed guidelines are available to assist the clinician in the day-to-day management of patients. Previous epidemiological surveys of climacteric symptoms have been criticised because of inadequate methodology. We have attempted to overcome most of these problems and to provide a more detailed analysis of the relationships between menopausal status and psychological and somatic symptoms. Eight hundred and fifty pre-, peri- and post-menopausal women, aged 45-65 yr, took part in a cross-sectional survey of general health, psychosocial factors and current symptomatology. They were a non-menopause clinic sample and were blind to the purpose of the study. Using a principal components analysis, the relationships between symptoms were examined. Certain psychological and somatic symptoms occurred together in specific clusters. Some of these symptom clusters, e.g., vasomotor symptoms and sexual difficulties, were best predicted solely by menopausal status, while others, such as psychological and somatic symptoms, were more clearly associated with psychosocial factors. On the basis of these results, guidelines for the assessment of climacteric and post-menopausal women can be suggested.

11.
Int J Sport Nutr Exerc Metab ; 17(4): 378-90, 2007 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-17962712

RESUMEN

The purpose of this investigation was to determine whether echinacea supplementation results in alterations of erythroid growth factors and erythropoietic status. Twenty-four men age 24.9 +/- 4.2 y, height 1.7 +/- 0.8 m, weight 87.9 +/- 14.6 kg, and 19.3% +/- 6.5% body fat were grouped using a double-blind design and self- administered an 8000-mg/d dose of either echinacea (ECH) or placebo (PLA) in 5 x 400 mg x 4 times/d for 28 d. Blood samples were collected and analyzed for red blood cells (RBCs), hematocrit (Hct), hemoglobin (Hb), mean corpuscular volume, mean corpuscular hemoglobin content, prostaglandin E2, ferritin, erythropoietin (EPO), interleukin 3 (IL-3), and granulocyte-macrophage-colony-stimulating factor using automated flow cytometry and ELISA. ANOVA was used to determine significant differences (P ? 0.05). EPO was greater (P < 0.001) in ECH at Days 7, 14, and 21 and reflected a 44%, 63%, and 36% increase, respectively. IL-3 was greater (P = 0.011) in ECH at Days 14 and 21, which indicated a 65% and 73% increase, respectively. These data indicate that ECH supplementation resulted in an increase in EPO and IL-3 but did not significantly alter RBCs, Hb, or Hct.


Asunto(s)
Echinacea , Eritropoyesis/efectos de los fármacos , Eritropoyetina/sangre , Administración Oral , Adulto , Análisis de Varianza , Área Bajo la Curva , Recuento de Células Sanguíneas , Suplementos Dietéticos , Método Doble Ciego , Índices de Eritrocitos/efectos de los fármacos , Eritropoyesis/inmunología , Eritropoyesis/fisiología , Citometría de Flujo , Humanos , Interleucina-3/sangre , Masculino , Factores de Tiempo
12.
J Br Menopause Soc ; 12 Suppl 1: 4-7, 2006 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-16513012

RESUMEN

A new form of continuous combined hormone replacement therapy has become available that contains estradiol and drospirenone as the progestogen component. Drospirenone is a synthetic progestogen, the only one in hormone replacement therapy in the UK that possesses clinically relevant anti-mineralocorticoid activity. The combination of estradiol and drospirenone has been shown to provide relief from estrogen-deficiency symptoms of the menopause. It also helps to prevent osteoporosis in postmenopausal women by increasing bone density. Further, it has been shown to provide protection against endometrial hyperplasia associated with unopposed estrogen therapy.


Asunto(s)
Androstenos/administración & dosificación , Hiperplasia Endometrial/prevención & control , Estradiol/administración & dosificación , Terapia de Reemplazo de Hormonas/métodos , Anciano , Relación Dosis-Respuesta a Droga , Esquema de Medicación , Quimioterapia Combinada , Hiperplasia Endometrial/patología , Femenino , Estudios de Seguimiento , Terapia de Reemplazo de Hormonas/efectos adversos , Humanos , Menopausia/efectos de los fármacos , Menopausia/fisiología , Persona de Mediana Edad , Estudios Multicéntricos como Asunto , Ensayos Clínicos Controlados Aleatorios como Asunto , Medición de Riesgo , Resultado del Tratamiento , Reino Unido
14.
J Strength Cond Res ; 18(4): 741-6, 2004 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-15574077

RESUMEN

The purpose of this investigation was to determine the effect of hyperhydration on the electromyographic (EMG) and mechanomyographic (MMG) responses during isometric and isokinetic muscle actions of the biceps brachii. Eight (22.1 +/- 1.8 years, 79.5 +/- 22.8 kg) subjects were tested for maximal isometric, submaximal isometric, and maximal concentric isokinetic muscle strength in either a control (C) or hyperhydrated (H) state induced by glycerol ingestion while the EMG and MMG signals were recorded. Although fluid retention was significantly greater during the H protocol, the analyses indicated no change in torque, EMG amplitude, EMG mean power frequency (MPF), MMG amplitude, or MMG MPF with hyperhydration. These results indicated that glycerol-induced fluid retention does not affect the torque-producing capabilities of a muscle, the impulses (EMG) going to a muscle, or muscular vibrations (MMG). It has been suggested that EMG and MMG can be used as direct electrical/mechanical monitoring, which could be presented to trainers and athletes; however, before determining the utility of these signals, the MMG and EMG responses should be examined under a variety of conditions such as in the present study.


Asunto(s)
Brazo/fisiología , Glicerol/administración & dosificación , Músculo Esquelético/fisiología , Miografía/métodos , Adulto , Análisis de Varianza , Fenómenos Biomecánicos , Deshidratación/fisiopatología , Electromiografía , Femenino , Humanos , Contracción Isométrica/fisiología , Masculino , Músculo Esquelético/efectos de los fármacos , Torque
15.
Endocrine ; 24(3): 187-93, 2004 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-15542884

RESUMEN

The regulatory authority in the UK, the Committee on Safety of Medicines, issued advice to health professionals on the day the results of the Million Women Study (MWS) were published. This course of action was undertaken before review of the study by the international medical and scientific community. We have reviewed the methodology of the MWS. It is our belief that the flaws in the design render the results largely uninterpretable because built in biases have affected risk estimates.


Asunto(s)
Neoplasias de la Mama/inducido químicamente , Terapia de Reemplazo de Estrógeno/efectos adversos , Proyectos de Investigación , Salud de la Mujer , Sesgo , Neoplasias de la Mama/diagnóstico por imagen , Neoplasias de la Mama/epidemiología , Femenino , Humanos , Mamografía , Persona de Mediana Edad , Sensibilidad y Especificidad , Reino Unido
17.
J Br Menopause Soc ; 10(3): 118-22, 2004 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-15494104

RESUMEN

The effects of oestrogen on brain ageing, cognition and neuropsychiatric disorder are an important public health issue, which, despite intensive research, has yet to be resolved. Evidence from basic science demonstrates that oestrogen has multiple protective effects on neurons and neurotransmitter systems. However, the evidence for oestrogen having a clinical role in the treatment and prevention of neuropsychiatric disorders is not well established. Here we review research into the effects of oestrogen on brain maturation and function and discuss the role for oestrogen replacement therapy (ERT) as a therapeutic tool.


Asunto(s)
Enfermedad de Alzheimer/fisiopatología , Encéfalo/metabolismo , Estrógenos/metabolismo , Envejecimiento , Trastorno Depresivo/fisiopatología , Terapia de Reemplazo de Estrógeno , Femenino , Humanos , Esquizofrenia/fisiopatología
18.
Br J Haematol ; 124(6): 802-8, 2004 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-15009069

RESUMEN

Whether hormone replacement therapy (HRT) is beneficial for coronary heart disease (CHD) is controversial. We hypothesized that continuous combined transdermal HRT may have benefits on CHD risk markers without the potential adverse effects seen with certain other HRT regimens. Sixty apparently healthy postmenopausal women, aged 40-65 years, entered a prospective, double-blind, randomized, placebo-controlled clinical trial; 55 women completed the 6-month study. Women received either transdermal oestradiol 17beta 0.05 mg and norethisterone acetate 0.125 mg daily, or identical placebo. Circulating markers of vascular function and remodelling, forearm blood flow, lipids and lipoproteins, glucose and insulin, and haemostatic safety parameters were measured at baseline and after treatment. Compared with placebo after 6 months, HRT administration resulted in decreased E-selectin (P < 0.01), and angiotensin-converting-enzyme (ACE; P = 0.05). Cholesterol (P < 0.05), low-density lipoproteins (LDL; P < 0.05), high-density lipoprotein3 (HDL3; P < 0.05) and apolipoproteins AII (P < 0.05) and B (P < 0.05), and fasting insulin (P < 0.05) also decreased in the HRT group. Factor VII coagulation activity decreased (P < 0.01) and plasminogen activator inhibitor-1 and fibrin D-dimer increased (P < 0.05) in the HRT group, whilst prothrombin fragment 1 + 2 (P < 0.05) decreased, more so in the placebo group. There were no changes in matrix metalloproteinase (MMP)-2, or in LDL particle size. This transdermal HRT had beneficial effects on vascular function and CHD risk markers.


Asunto(s)
Enfermedades Cardiovasculares/prevención & control , Terapia de Reemplazo de Estrógeno/métodos , Noretindrona/análogos & derivados , Posmenopausia/sangre , Administración Cutánea , Adulto , Antropometría , Biomarcadores/sangre , Glucemia/metabolismo , Enfermedades Cardiovasculares/sangre , Preparaciones de Acción Retardada , Combinación de Medicamentos , Métodos Epidemiológicos , Estradiol/administración & dosificación , Femenino , Hemostasis/efectos de los fármacos , Humanos , Insulina/sangre , Lípidos/sangre , Lipoproteínas/sangre , Persona de Mediana Edad , Noretindrona/administración & dosificación , Acetato de Noretindrona
19.
Med Sci Sports Exerc ; 35(1): 150-6, 2003 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-12544649

RESUMEN

PURPOSE: To compare glycerol and water hyperhydration and rehydration on tennis related skill and agility performance. METHODS: Eleven male subjects completed two counter-balanced, double-blind trials. Each trial consisted of three phases: 1). hyperhydration with or without glycerol (1.0 g.kg/(-1)) over 150 min, 2). 120 min of exercise-induced dehydration (EID), and 3) rehydration with or without glycerol (0.5 g.kg(-1)) over 90 min. After each phase, subjects performed 5- and 10-m sprint tests, a repeated-effort agility test, and tennis skill tests. RESULTS: Glycerol (G) hyperhydration significantly increased fluid retention by approximately 900 mL over the placebo (P) (P

Asunto(s)
Glicerol/uso terapéutico , Soluciones para Rehidratación , Carrera/fisiología , Análisis y Desempeño de Tareas , Agua , Adulto , Estudios Cruzados , Deshidratación/prevención & control , Método Doble Ciego , Humanos , Masculino , Volumen Plasmático , Tenis/fisiología
20.
Exp Gerontol ; 38(1-2): 109-17, 2003.
Artículo en Inglés | MEDLINE | ID: mdl-12543268

RESUMEN

The population of the western world is ageing. This increase in the elderly population will inevitably mean a rise in the prevalence of age-related cognitive decline and late-onset neuropsychiatric disorder, such as Alzheimer's disease (AD). There are sex differences in the incidence and age of onset of these disorders. Sex steroids and sex chromosomes are therefore implicated in their pathophysiology. We have identified relevant past and current literature using a Medline search and from the references of relevant papers. These were then reviewed and relevant articles have been summarized and included in the review. Evidence is presented for the wide-ranging actions of estrogen in the brain at the cellular, metabolic and neurotransmitter levels as well as from the cognitive, AD, depression and cerebrovascular perspectives. The authors conclude that it is unlikely that estrogen will become a stand-alone treatment for any of these disorders, although there may still be a role as an adjunctive treatment and as a prophylactic measure.


Asunto(s)
Envejecimiento/fisiología , Encéfalo/efectos de los fármacos , Terapia de Reemplazo de Estrógeno , Fármacos Neuroprotectores/uso terapéutico , Sexo , Anciano , Enfermedad de Alzheimer/prevención & control , Encéfalo/metabolismo , Trastornos Cerebrovasculares/metabolismo , Trastornos Cerebrovasculares/prevención & control , Demencia/metabolismo , Demencia/prevención & control , Depresión/tratamiento farmacológico , Dopamina/metabolismo , Femenino , Humanos , Masculino , Enfermedades Neurodegenerativas/metabolismo , Enfermedades Neurodegenerativas/prevención & control , Norepinefrina/metabolismo , Serotonina/metabolismo
SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA
...