RESUMEN
Patients with familial adenomatous polyposis (FAP) develop multiple premalignant colorectal adenomas. Untreated, one or more of these polyps will progress to colorectal carcinoma in middle-aged adults. Extra-intestinal manifestations of FAP are frequently observed and this combination has been called Gardner's syndrome. Oral and maxillofacial symptoms of FAP include an increased risk of jaw osteomas, odontomas and supernumerary or unerupted teeth. Early diagnosis of FAP is crucial and may be life saving. As oral signs usually precede gastrointestinal symptoms, the dentist may play an important role in the diagnosis of FAP.
Asunto(s)
Poliposis Adenomatosa del Colon/complicaciones , Neoplasias Faciales/etiología , Neoplasias Maxilomandibulares/etiología , Enfermedades Dentales/etiología , Poliposis Adenomatosa del Colon/genética , Síndrome de Gardner/diagnóstico , Humanos , Odontoma/etiología , Osteoma/etiología , Diente Supernumerario/etiología , Diente no Erupcionado/etiologíaRESUMEN
Patients suffering from familial adenomatosis polyposis develop multiple pre-malignant gastrointestinal polyps and are at high risk of developing colon cancer. In addition extra-intestinal manifestations are observed frequently. The combination of extra-intestinal manifestations and familial adenomatosis polyposis is named Gardner's syndrome. An early diagnosis of this disease is important because it could mean a better prognosis for the patient. This review describes the oral and maxillofacial symptoms of FAP, and its potential implications for dental treatment.
