Clinical outcomes of non-surgical root canal obturations using NeoMTA: A retrospective series of case reports.

NeoMTA is a commercially available tricalcium silicate-based cement intended for contact with pulp and periradicular tissues. The purpose of this study was to retrospectively evaluate the outcomes of non-surgical root canal treatments with NeoMTA obturations. Patients were treated in a private endodontic practice between 2015 and 2018. All cases, including initial treatments and retreatments, were either fully obturated with NeoMTA, or using gutta-percha with NeoMTA as an endodontic sealer. Outcomes were assessed using follow-up examination data with digital periapical radiographs with a minimum of a 1-year recall. Teeth were classified based on the clinical examination as: healed/healing (success), or non-healed (failure). 265 teeth were included with an average follow-up time of 1.3 years. The overall success rate was 91.7%. Only the presence of a pre-operative periapical radiolucency was found to significantly affect success. Comparison of obturation techniques demonstrated no effect on outcomes. NeoMTA is suitable for endodontic obturation.

Scleroderma and multiple teeth with invasive cervical resorption: is there a connection?

Scleroderma is a chronic connective tissue disease generally classified as an autoimmune rheumatic disease. Symptoms may include thickening of the skin, calcifications, Raynaud syndrome, and esophageal problems. Invasive cervical resorption is an aggressive form of external resorption localized in the cervical part of the tooth. Its etiology remains uncertain. This case report describes invasive cervical resorption affecting 4 teeth in a 44-year-old woman with scleroderma and speculates on the possible relationships between these disease entities.

Retrospective Analysis of Root-end Microsurgery Outcomes in a Postgraduate Program in Endodontics Using Calcium Silicate-based Cements as Root-end Filling Materials.

INTRODUCTION: The purpose of this retrospective study was to determine the clinical and radiographic outcomes of root-end microsurgery in a postgraduate program in endodontics using modern techniques and calcium silicate-based root-end filling materials (ProRoot MTA; Dentsply International, Johnson City, TN, and EndoSequence Root Repair Material [ERRM]; Brasseler USA, Savannah, GA) and to identify any potential prognostic factors that may have affected healing outcomes. METHODS: Clinical records and periapical radiographs were collected from patients who had undergone endodontic microsurgery between 2007 and 2018 in a postgraduate endodontic clinic with a minimum follow-up interval of 6 months. Either ProRoot MTA or ERRM was used as the root-end filling material. Outcomes were categorized into healed, healing, and nonhealing based on clinical and radiographic findings. Healed and healing cases were pooled and considered as successes, whereas nonhealing cases were considered as failures. RESULTS: A total of 129 patients with 142 teeth were included in the final analysis. Seventy-six cases were root-end filled with ProRoot MTA and 66 root-end filled with ERRM. The ProRoot MTA group had a success rate of 92.1%, and the ERRM group had a success rate of 92.4% with no significant difference between the groups (P > .05). Vertical root fracture was found to be the predominant cause of failure. No patient- or treatment-related factor was identified to have any significant impact on healing. CONCLUSIONS: High overall success can be achieved in a postgraduate endodontic program when either ProRoot MTA or ERRM is used as the root-end filling material.

Comparison of optical performance among three dental operating microscopes: A pilot study.

INTRODUCTION: Two important aspects of the dental operating microscope (DOM) that factor into its overall effectiveness are resolution and depth of field. Therefore, the objective of this study was to evaluate and compare the resolution and depth of field of DOMs from three well-known manufacturers using standardized test targets. MATERIALS AND METHODS: A resolution test, using the 1951 USAF Hi-Resolution Target (Edmund Optics, Barrington, NJ), and a depth of field test, using the Depth of Field Target 5-15 (Edmund Optics, Barrington, NJ), were performed by two calibrated observers. Three DOM systems such as Seiler IQ (Seiler Instrument Inc., St. Louis, USA), Global G-Series 6 step (Global Surgical Corp., St. Louis, USA), and Zeiss Extaro 300 (Carl Zeiss Meditec AG, Oberkochen, Germany) were used to compare the resolution and depth of field. RESULTS: The Zeiss Extaro 300 showed the highest maximum resolution and maximum DOF (64 lp/mm and 17mm, respectively). The Seiler IQ showed the lowest maximum resolution and maximum DOF (35.9 lp/mm and 11 mm, respectively). CONCLUSION: Within the limitations of this study, the Zeiss Extaro 300 was superior in terms of resolution and depth of field as compared to the other two DOMs.

International volunteer activities of US dentists: results of a survey.

Although several recent studies have gauged the participation of US dental schools and dental students in international volunteer programs, no study of US dentists' international dental volunteer activities has been published to date. The goal of this study was to quantify that participation and explore dentists' motivation for service. A web-based survey was developed, and, in August 2018, a hyperlink to a web-based survey consisting of 12 questions was sent to 19,679 US dentists whose names and contact information were obtained from a commercially obtained email list. All respondents were volunteers, and no compensation was offered. Of the 19,679 potential respondents contacted via email, 1295 (6.6%) participated in the survey. Some respondents did not answer all the survey questions. A majority (79.2%) were 51 years or older, and 41.9% of respondents reported having participated in volunteer dental activities outside the United States. Of those dentists, 99.6% reported having had positive experiences, and 98.8% reported that they would recommend this activity to other dentists. Among the respondents, 27.4% reported having volunteered more than once, and 12.1% reported that they volunteered regularly.

Histology of NeoMTA Plus and Quick-Set2 in Contact with Pulp and Periradicular Tissues in a Canine Model.

INTRODUCTION: NeoMTA Plus (Avalon Biomed Inc, Bradenton, FL) is a tricalcium silicate material similar to the first mineral trioxide aggregate product, ProRoot MTA (Dentsply Sirona, York, PA), but with improvements such as decreased setting time, increased ion release, increased water sorption, and nonstaining radiopacifiers. Quick-Set2 (Avalon Biomed Inc) is a newly formulated calcium aluminosilicate material that has a faster setting time and increased acid resistance and is nonstaining. The purpose of this study was to compare the healing of pulpal and periapical tissues in dogs after exposure to NeoMTA Plus and Quick-Set2 after pulpotomy and root-end surgery procedures. METHODS: Seventy-two teeth (36 for each procedure) in 6 beagle dogs received pulpotomy or root-end surgery using either NeoMTA Plus or Quick-Set2. The dogs were sacrificed at 90 days, and the teeth and surrounding tissues were prepared for histologic evaluation. Sixty teeth were evaluated and scored histologically (29 with pulpotomies and 31 with root-end resections). Specimens were scored for inflammation, quality and thickness of dentin bridging, pulp tissue response, cementum and periodontal ligament formation, and apical bone healing. RESULTS: Both materials displayed favorable healing at 90 days. The only significant difference was the quality of dentin bridge formation in pulpotomies using NeoMTA Plus compared with Quick-Set2. CONCLUSIONS: Quick-Set2 and NeoMTA Plus had similar effects on inflammation, pulp response, periodontal ligament and cementum formation, and apical tissue healing in dogs. NeoMTA Plus had superior dentin bridge quality compared with Quick-Set2.

Bioactive endodontic materials for everyday use: a review.

Bioceramic materials are at the forefront of modern dentistry. Bioactive bioceramic endodontic materials promote pulpal and periapical tissue healing and are easy to use. Dentists can choose among many endodontic materials, depending on their needs. This article highlights the major differences among commercially available bioactive tricalcium silicate bioceramics, commonly known as mineral trioxide aggregate materials, to enable dentists to make appropriate decisions in the selection of these materials.

A National Survey of U.S. Dental Students' Experiences with International Service Trips.

Globalization, along with the increasing prevalence of non-communicable diseases, their risk factors, and poor oral health, demands global approaches to oral health care. Trained health care workers' providing volunteer services abroad is one model used for improving access to dental services for some communities. Currently, little is known about U.S. dental student involvement in international clinical service volunteerism. The aim of this exploratory study was to capture national survey data from predoctoral dental students about their interest in and experience with global health service trips. The survey sought to assess students' past experiences and current and future interest in programs providing dental and/or medical services in order to lay the foundation for further research. A 12-question web-based survey was distributed in May 2017 to 22,930 students enrolled in U.S. dental schools. A total of 1,555 students responded, for a response rate of 7%. Respondents were evenly distributed across the four academic years. Approximately 22% (n=342) of the respondents had already participated in a service trip experience, 83% reported interest in a service trip while in school, and 92% were interested after graduation. Reported motivations for international trips included the desire to care for the underserved and to obtain a more global view of health and disease. Concerns were expressed regarding costs and time constraints. This study provided preliminary, exploratory data on dental student engagement with international service trips. Both interest and participation in international service trips among responding students were high, reflecting current trends in both dentistry and medicine. Dental education may have an opportunity to guide student engagement in more sustainable and ethical volunteering in the U.S. and abroad.

Visual Fixation and Scan Patterns of Dentists Viewing Dental Periapical Radiographs: An Eye Tracking Pilot Study.

INTRODUCTION: The visual search patterns of dentists and the areas that attract their attention when interpreting dental periapical radiographs are currently unknown. This research identifies areas and patterns of visual fixation when observing dental periapical radiographs. METHODS: In an observational study using eye tracking technology and a convenience sample of 44 observers, the interpretations of 4 dental periapical radiographs were recorded using Camtasia Software (TechSmith, Okemos, MI) with a gaze tracking "bubble" denoting where within the radiograph the observers' eyes gazed. The recorded observations included the scanning pattern, the area of first fixation, and revisits of areas. Also noted was whether the area of first fixation or revisit was radiopaque, radiolucent, or of normal radiodensity and whether it was a coronal or radicular area. RESULTS: The first fixation is more likely to be an area of high contrast that is either radiopaque or radiolucent compared with areas that were normal or of average gray scale. Significantly more revisits occurred on areas that were radiopaque and located in the radicular area. Of the 4 categorized scanning patterns, tooth by tooth scanning predominated. CONCLUSIONS: When interpreting dental periapical radiographs, significantly more observers initially fixated on areas of the radiograph that were of high contrast (ie, radiopaque or radiolucent) compared with "normal areas." A tooth by tooth scanning pattern was most commonly used.

Intraradicular Appearances Affect Radiographic Interpretation of the Periapical Area.

INTRODUCTION: No research exists evaluating the influences of specific variables such as obturation length, radiodensity, or the presence of voids on interpretation of periradicular area. The purpose of this study was to evaluate the effects of obturation length, radiodensity, and the presence of voids on the radiographic interpretations of periapical areas. METHODS: In a Web-based survey, 3 test image groups of variable obturation lengths, radiodensities, and numbers of voids were presented to observers for evaluation of the periapical areas. Intracanal areas of the images were altered by using Adobe Photoshop to create 3 test image groups. Each observer reviewed 2 control images and 1 image from each test image group. Responses were recorded in a 5-point Likert-type scale. Within each test image group, the periapical areas were identical. Kruskal-Wallis, Mann-Whitney U, and Cliff's delta statistical tests were used to analyze results. RESULTS: A total of 748 observer responses were analyzed. Significant differences (P ≤ .01) in the median Likert-type scale responses were identified between the following paired groups: 3 mm short and 1 mm short, 3 mm short and flush, lower radiodensity and higher radiodensity, lower radiodensity and intermediate radiodensity, no voids and several voids, and several voids and single void. Effect sizes ranged from 0.19 to 0.41. CONCLUSIONS: Significant differences were noted within all 3 test image groups: length, radiodensity, and presence of voids. Length of obturation had the largest effect on interpretation of the periapical area, with the 3 mm short radiographic obturation length image interpreted less favorably.

Long-term Clinical Outcome of Teeth Obturated with Resilon.

INTRODUCTION: Although Resilon has been in clinical use as an endodontic obturation material for more than a decade, there is a lack of long-term clinical outcome studies. The purpose of this retrospective case-control study was to compare long-term clinical outcomes in teeth obturated with Resilon/RealSeal SE (RS) and GP/AH Plus (GP). METHODS: One hundred teeth treated at Texas A&M University College of Dentistry between 2007 and 2012 were included; 50 teeth were obturated with RS and 50 with GP. All cases were initial treatments without preoperative periapical radiolucencies. Success and failure were assessed on the basis of clinical signs and symptoms and/or the presence of periapical radiolucency. Chi-square test and odds ratio were used to determine the association between the obturation material and outcome. Potential prognostic factors were evaluated including age, sex, tooth location, preoperative diagnosis, and one versus multiple visits. RESULTS: The average recall time for RS was 5.8 years and 6.6 years for GP. Fifty-six percent of RS-obturated teeth were classified as successful at recall compared with 88% of GP-obturated teeth. RS had 5.7 times greater odds of failure compared with GP (P < .001). When periapical radiolucencies were present, they tended to be larger and involve multiple roots in the RS group compared with GP group. None of the prognostic factors examined were found to have any significant effect on outcome. CONCLUSIONS: Within the limitations of this study, teeth obturated with RS had 5.7 times greater chance of failure compared with teeth obturated with GP.

Coronal and Intraradicular Appearances Affect Radiographic Perception of the Periapical Region.

INTRODUCTION: The influence of the radiographic appearances of the coronal and intraradicular areas on periapical radiographic interpretation has been minimally evaluated in dentistry and endodontics. The purpose of this study was to evaluate the effects that the coronal and intraradicular radiographic appearance has on endodontists' radiographic interpretations of periapical areas. METHODS: In a split-group study design using an online survey format, 2 pairs of digital periapical radiographic images were evaluated by 2 groups (A and B) of endodontist readers for the presence of a periapical finding. The images in each pair were identical except that 1 image of each image pairs had coronal restorations and/or root canal fillings altered using Adobe Photoshop software (Adobe Systems, San Jose, CA). The periapical areas were not altered. Using a 5-point Likert scale, the endodontist readers were asked to "Please evaluate the periapical area(s)." A Mann-Whitney U test was used to statistically evaluate the difference between the groups. Significance was set at P < .01. RESULTS: There were 417 readers in group A and 442 readers in group B. The Mann-Whitney U test showed a significant difference in the responses between the groups for both image pairs (P < .01). CONCLUSIONS: Because the periapical areas of the image pairs were unaltered, the differing coronal and intraradicular areas of the radiographs appear to have influenced endodontists' interpretations of the periapical areas. This finding has implications for all radiographic outcome assessments.

International Volunteer Programs for Dental Students: Results of 2009 and 2016 Surveys of U.S. Dental Schools.

The aims of this study were to determine the prevalence and nature of international volunteer programs for predoctoral students at U.S. dental schools and to document the change over five years. Web-based surveys were conducted in 2009 and 2016. An invitation to participate in the study, along with a hyperlink to the survey, was emailed to the deans of all U.S. dental schools in the two years. In 2009, 47 of 58 dental school deans responded to the survey, for a response rate of 81%. In 2016, 48 of 64 dental school deans responded, for a response rate of 75%. From 2009 to 2016, the number of schools reporting dental student international experiences increased from 25 to 31. In 2016, 65% of responding schools offered dental student international experiences, an 11.5% increase over the results of the 2009 survey. Concomitantly, the number of deans reporting their students' participation in international opportunities not officially sanctioned by the school decreased from 41 to 34. These findings showed an increase in the number of dental schools providing international experiences for their students and established baseline data to assess trends in the future.

Clinical and Patient-centered Outcomes of Nonsurgical Root Canal Retreatment in First Molars Using Contemporary Techniques.

INTRODUCTION: There have been many recent technical advances in modern endodontics that have the potential to affect treatment outcomes. Reports on treatment outcomes using contemporary techniques are relatively scarce, especially in the field of nonsurgical retreatment. The purpose of this study was to determine the success of nonsurgical root canal retreatment in molars using contemporary endodontic techniques. METHODS: Sixty-three patients referred for retreatment in first molars were enrolled in the study. The retreatment procedures were performed by endodontic residents using a semistandardized treatment protocol. Patients were followed-up at 6, 12, and 24 months. Treatment outcomes were categorized into healed, healing, or nonhealing based on clinical and radiographic criteria. Healed and healing were considered as successes, and nonhealing was considered a failure. Outcomes were also evaluated using patient-centered criteria that included oral health-related quality of life scores and subjective chewing ability. RESULTS: Fifty-two of the 63 patients were available for final analysis. Five cases (9.6%) were determined to be nonhealing at the last follow-up with new or persistent periapical lesions. Thirty-seven (71.2%) patients had complete resolution of apical periodontitis, and the remaining 10 (19.2%) remained asymptomatic and showed radiographic evidence of healing. Oral health-related quality of life scores and chewing ability improved significantly over time (P < .05), with the biggest increase observed within the first week of treatment completion. CONCLUSIONS: This study showed that endodontic retreatment using contemporary techniques significantly improved patients' quality of life and chewing ability over time, with a success rate of 90.4% after 2 years.

Comparative Analysis of Calcium Silicate-based Root Filling Materials Using an Open Apex Model.

INTRODUCTION: Many new calcium silicate-based root filling materials have emerged in the market; however, their performance in the orthograde obturation of an open apex has not been evaluated. The purpose of this study was to compare the marginal adaptation of ProRoot MTA (Dentsply Tulsa Dental, Tulsa, OK), NeoMTA Plus (Avalon Biomed Inc, Bradenton, FL), and Endosequence BC RRM-Fast Set Putty (BC RRM-FS; Brasseler USA, Savannah, GA) after orthograde placement in roots with open apices. METHODS: Palatal roots of maxillary molars were instrumented to create divergent open apices and divided into 4 groups for orthograde obturation: ProRoot MTA, NeoMTA Plus, BC RRM-FS, and BC RRM-FS + BC Sealer. Using a scanning electron microscope, the quality of material adaptation at the anatomic apex was evaluated by 5 blinded examiners; 3 mm of the root end was sectioned, and gap distance was measured at the material-dentin interface. Statistical analyses were performed using the Kruskal-Wallis test. RESULTS: There were no significant differences in marginal adaptation among the 4 groups at the level of the anatomic apex (P = .175). BC RRM-FS + BC Sealer had a significantly smaller gap size after 3-mm root end resection compared with the other 3 groups (P < .01). No differences were observed among the other 3 materials. CONCLUSIONS: All materials showed comparable marginal adaptation at the anatomic apex when used for orthograde obturation of open apices. Application of BC Sealer before the delivery of BC RRM-FS Putty enhanced the quality of adaptation coronal to the apex.

Histologic Assessment of Quick-Set and Mineral Trioxide Aggregate Pulpotomies in a Canine Model.

INTRODUCTION: Quick-Set (Primus Consulting, Bradenton, FL) is a calcium aluminosilicate cement that is a potential alternative to mineral trioxide aggregate (MTA) with greater acid resistance and faster setting. The purpose of this study was to compare the effects of Quick-Set and MTA on pulpal tissues in response to pulpotomy procedures. METHODS: The pulp chambers of 42 maxillary teeth in 7 beagle dogs were accessed, and the coronal pulpal tissue was removed. Pulpotomy procedures were performed, placing the experimental materials directly over the radicular pulp tissues. The dogs were sacrificed at 70 days, and the teeth and surrounding tissues were removed and prepared for histologic analysis. The sections of the pulpotomy areas were scored for inflammation, pulp tissue organization, reactionary dentin formation, and quality of dentinogenesis. RESULTS: The Quick-Set group exhibited significantly more pulpal inflammation (P = .002) and significantly less pulp tissue organization (P = .004). No significant difference was noted for reactionary dentin formation (P = .526) and quality of dentinogenesis (P = .436). CONCLUSIONS: Compared with ProRoot White MTA (Dentsply Tulsa Dental Specialties, Tulsa, OK), Quick-Set exhibited more pulpal inflammation and decreased pulp tissue organization. No significant differences were noted for reactionary dentin formation and quality of dentinogenesis.

Residents' Perceptions of the Graduate Endodontic Application Selection Process and Match.

INTRODUCTION: Anecdotal reports suggest that the application process for graduate endodontic programs in the United States and Canada is inefficient and may be perceived by applicants as being unfair. This survey examines residents' perceptions of the graduate endodontic application process and related issues. METHODS: A web-based survey consisting of 24 questions on the residents' perception of the graduate endodontic application process was developed and e-mailed to 403 graduate endodontic students in the United States and Canada. RESULTS: Of the 403 invited participants, 218 surveys were completed (53%). The responses were varied. Respondents were not overwhelmingly satisfied with the application/interview/selection process; 45% were satisfied or very satisfied, 25% were neutral, and 30% were dissatisfied or very dissatisfied. Only 39% indicated that they would have preferred a Match process. Eighty-two percent accepted the first program that offered a position, and 79% reported being satisfied or very satisfied with their choice of a program. CONCLUSIONS: Forty-five percent of endodontic residents were satisfied with the application/interview/selection process, and most would not have preferred a Match process.

The effect of obturation technique on the push-out bond strength of calcium silicate sealers.

INTRODUCTION: Calcium silicate-based sealers are known to have excellent sealing ability and bioactivities. They are typically recommended to be used in a single-cone (SC) technique. No studies have evaluated the effects of the thermoplastic obturation technique on the dentin interface of these sealers. The purpose of this study was to evaluate the push-out bond strengths of MTA Plus Sealer (Avalon Biomed Inc, Bradenton, FL) and EndoSequence BC Sealer (BC; Brasseler USA, Savannah, GA) when they were used in a thermoplastic technique. METHODS: Fifty single-rooted human extracted teeth were randomly divided into 5 groups (n = 10), instrumented, and obturated with the SC technique or continuous wave (CW) technique: group 1, BC-SC; group 2, BC-CW; group 3, MTA Plus-SC; group 4, MTA Plus-CW; and group 5, AH Plus (Dentsply DeTrey, Konstanz, Germany)-CW. The roots were sectioned into 1.0-mm-thick slices, and bond strengths were measured using a standardized push-out test. The mode of failure was determined by visual inspection under magnification. RESULTS: The MTA Plus-CW had statistically significant lower bond strengths than all other groups. The BC-SC group had statistically higher bond strengths than the MTA Plus-SC and AH Plus-CW groups. No significant differences were seen among the other groups. Modes of failure were predominately cohesive or mixed except for group 4 (ie, MTA Plus-CW) in which nearly half the specimens had no visible sealer. CONCLUSIONS: BC and MTA Plus sealer showed favorable bond strengths when used in an SC technique. The CW obturation technique decreased the bond strengths of these sealers.

Comparison of Quick-Set and mineral trioxide aggregate root-end fillings for the regeneration of apical tissues in dogs.

INTRODUCTION: Quick-Set (Avalon Biomed Inc, Bradenton, FL) is a calcium aluminosilicate cement that is a potential alternative to mineral trioxide aggregate (MTA) with greater acid resistance and faster setting. The purpose of this study was to compare the regeneration of apical tissues after root-end surgery when the apical tissues were exposed to Quick-Set or White ProRoot MTA (Dentsply Tulsa Dental Specialties, Tulsa, OK) by root-end resection. METHODS: The root canals of 42 mandibular premolars in 7 beagle dogs were accessed, cleaned and shaped, and obturated with Quick-Set or white MTA. Osteotomies and root-end resections were performed immediately. The dogs were sacrificed at 90 days, and the teeth and surrounding tissues were removed and prepared for histologic analysis. The sections of the apical areas were scored for inflammation, new cementum formation, periodontal ligament formation, and bone quality. RESULTS: At 90 days, both materials supported some degree of cementum formation on the surface of the material, periodontal ligament regeneration, and excellent bone quality. The only significant difference was greater inflammation found in the Quick-Set group. CONCLUSIONS: Quick-Set and White ProRoot MTA had a similar effect on bone quality, cementum formation, and periodontal ligament formation after root-end surgery in dogs. Quick-Set was associated with greater inflammation.

Capping a pulpotomy with calcium aluminosilicate cement: comparison to mineral trioxide aggregates.

INTRODUCTION: Calcium aluminate cements have shown little affinity for bacterial growth, low toxicity, and immunogenicity when used as a restoration material, but calcium aluminate cements have not been tested in vivo in pulpotomy procedures. METHODS: To address this question, a calcium aluminosilicate cement (Quick-Set) was tested along with 2 mineral trioxide aggregates, ProRoot MTA and MTA Plus. These cements were used as a capping agent after pulpotomy. Control rats had no pulpotomy, or the pulpotomy was not capped. Proinflammatory cytokines interleukin (IL)-1ß and IL-1α were measured, and histology was performed at 30 and 60 days after capping. The nociceptive response was determined by measuring the lengthening of the rat's meal duration. RESULTS: and CONCLUSIONS: IL-1ß and IL-1α concentrations were reduced in the capped teeth, but no differences were observed among the 3 cements. Dentinal bridging could be detected at both 30 and 60 days with each of the 3 cements, and the pulps were still vital 60 days after capping. Meal duration significantly shortened after placement of the 3 different cements, indicating a nociceptive response, but there were no differences among the materials. Calcium aluminosilicate cement had similar properties to mineral trioxide aggregates and is a viable option for pulpotomy procedures.