Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 11 de 11
Filtrar
1.
BMC Public Health ; 15: 724, 2015 Jul 30.
Artículo en Inglés | MEDLINE | ID: mdl-26223781

RESUMEN

BACKGROUND: Hispanics, particularly men of Mexican origin, are more likely to engage in heavy drinking and experience alcohol-related problems, but less likely to obtain treatment for alcohol problems than non-Hispanic men. Our previous research indicates that heavy-drinking Hispanics who received a brief motivational intervention (BMI) were significantly more likely than Hispanics receiving standard care to reduce subsequent alcohol use. Among Hispanics who drink heavily the BMI effectively reduced alcohol use but did not impact alcohol-related problems or treatment utilization. We hypothesized that an adapted BMI that integrates cultural values and addresses acculturative stress among Hispanics would be more effective. METHODS/DESIGN: We describe here the protocol for the design and implementation of a randomized (approximately 300 patients per condition) controlled trial evaluating the comparative effectiveness of a culturally adapted (CA) BMI in contrast to a non-adapted BMI (NA-BMI) in a community hospital setting among men of Mexican origin. Study participants will include men who were hospitalized due to an alcohol related injury or screened positive for heavy drinking. By accounting for risk and protective factors of heavy drinking among Hispanics, we hypothesize that CA-BMI will significantly decrease alcohol use and alcohol problems, and increase help-seeking and treatment utilization. DISCUSSION: This is likely the first study to directly address alcohol related health disparities among non-treatment seeking men of Mexican origin by comparing the benefits of a CA-BMI to a NA-BMI. This study stands to not only inform interventions used in medical settings to reduce alcohol-related health disparities, but may also help reduce the public health burden of heavy alcohol use in the United States. TRIAL REGISTRATION: Trial registration clinicaltrials.gov identifier NCT02429401; Registration date: April 28, 2015.


Asunto(s)
Consumo de Bebidas Alcohólicas/etnología , Consumo de Bebidas Alcohólicas/terapia , Trastornos Relacionados con Alcohol/etnología , Trastornos Relacionados con Alcohol/terapia , Americanos Mexicanos , Entrevista Motivacional/métodos , Competencia Cultural , Hispánicos o Latinos , Humanos , Masculino , Tamizaje Masivo , Motivación , Proyectos de Investigación , Estados Unidos
2.
Am J Cardiol ; 113(10): 1599-605, 2014 May 15.
Artículo en Inglés | MEDLINE | ID: mdl-24792735

RESUMEN

The Immediate Myocardial Metabolic Enhancement During Initial Assessment and Treatment in Emergency care Trial of very early intravenous glucose-insulin-potassium (GIK) for acute coronary syndromes (ACS) in out-of-hospital emergency medical service (EMS) settings showed 80% reduction in infarct size at 30 days, suggesting potential longer-term benefits. Here we report 1-year outcomes. Prespecified 1-year end points of this randomized, placebo-controlled, double-blind, effectiveness trial included all-cause mortality and composites including cardiac arrest, mortality, or hospitalization for heart failure (HF). Of 871 participants randomized to GIK versus placebo, death occurred within 1 year in 11.6% versus 13.5%, respectively (unadjusted hazard ratio [HR] 0.83, 95% confidence interval [CI] 0.57 to 1.23, p = 0.36). The composite of cardiac arrest or 1-year mortality was 12.8% versus 17.0% (HR 0.71, 95% CI 0.50 to 1.02, p = 0.06). The composite of hospitalization for HF or mortality within 1 year was 17.2% versus 17.2% (HR 0.98, 95% CI 0.70 to 1.37, p = 0.92). The composite of mortality, cardiac arrest, or HF hospitalization within 1 year was 18.1% versus 20.4% (HR 0.85, 95% CI 0.62 to 1.16, p = 0.30). In patients presenting with suspected ST elevation myocardial infarction, HRs for 1-year mortality and the 3 composites were, respectively, 0.65 (95% CI 0.33 to 1.27, p = 0.21), 0.52 (95% CI 0.30 to 0.92, p = 0.03), 0.63 (95% CI 0.35 to 1.16, p = 0.14), and 0.51 (95% CI 0.30 to 0.87, p = 0.01). In patients with suspected acute coronary syndromes, serious end points generally were lower with GIK than placebo, but the differences were not statistically significant. However, in those with ST elevation myocardial infarction, the composites of cardiac arrest or 1-year mortality, and of cardiac arrest, mortality, or HF hospitalization within 1 year, were significantly reduced.


Asunto(s)
Síndrome Coronario Agudo/tratamiento farmacológico , Atención Posterior/métodos , Pacientes Ambulatorios , Síndrome Coronario Agudo/diagnóstico , Síndrome Coronario Agudo/mortalidad , Adulto , Soluciones Cardiopléjicas , Causas de Muerte/tendencias , Método Doble Ciego , Electrocardiografía , Femenino , Estudios de Seguimiento , Glucosa/administración & dosificación , Paro Cardíaco/mortalidad , Paro Cardíaco/prevención & control , Humanos , Infusiones Intravenosas , Insulina/administración & dosificación , Masculino , Persona de Mediana Edad , Miocardio/metabolismo , Potasio/administración & dosificación , Estudios Retrospectivos , Tasa de Supervivencia/tendencias , Factores de Tiempo , Resultado del Tratamiento , Estados Unidos/epidemiología
3.
Addict Behav ; 37(7): 817-23, 2012 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-22472523

RESUMEN

BACKGROUND: Motivational interviewing (MI) is widely used for adolescent smoking cessation but empirical support for this approach is mixed. METHODS: Adolescent cigarette smokers 14-18 years old (N=162) were recruited from medical, school, and community settings and randomly assigned to enhanced MI or brief advice (BA) for smoking cessation. MI comprised an in-person individual session, a telephone booster session one week later, and a brief telephone-based parent intervention. BA consisted of standardized brief advice to quit smoking. Assessments occurred at baseline, post-treatment and at 1-, 3-, and 6-month follow ups. RESULTS: Biochemically-confirmed 7-day point prevalence abstinence rates were low (e.g., 4.5% for MI; 1.4% for BA at 1 month) and did not differ significantly by group at any follow up. Only those in MI reported significant decreases in cigarettes smoked per day (CPD) from baseline to 1 month. At 3 and 6 months, smokers in both groups reported significantly reduced CPD with no differences between groups. MI reduced perceived norms regarding peer and adult smoking rates, while BA had no effect on normative perceptions. No group differences emerged for self-reported motivation or self-efficacy to quit smoking. CONCLUSIONS: Findings support the efficacy of MI for addressing normative misperceptions regarding peer and adult smoking and for modestly reducing CPD in the short-term; however, these effects did not translate to greater smoking abstinence. MI may have more promise as a prelude to more intensive smoking intervention with adolescents than as a stand-alone intervention.


Asunto(s)
Terapia Conductista/métodos , Consejo Dirigido/métodos , Motivación , Cese del Hábito de Fumar/métodos , Prevención del Hábito de Fumar , Adolescente , Femenino , Estudios de Seguimiento , Humanos , Masculino , Autoeficacia , Autoinforme , Fumar/epidemiología , Fumar/psicología , Cese del Hábito de Fumar/psicología , Resultado del Tratamiento
4.
JAMA ; 307(18): 1925-33, 2012 May 09.
Artículo en Inglés | MEDLINE | ID: mdl-22452807

RESUMEN

CONTEXT: Laboratory studies suggest that in the setting of cardiac ischemia, immediate intravenous glucose-insulin-potassium (GIK) reduces ischemia-related arrhythmias and myocardial injury. Clinical trials have not consistently shown these benefits, possibly due to delayed administration. OBJECTIVE: To test out-of hospital emergency medical service (EMS) administration of GIK in the first hours of suspected acute coronary syndromes (ACS). DESIGN, SETTING, AND PARTICIPANTS: Randomized, placebo-controlled, double-blind effectiveness trial in 13 US cities (36 EMS agencies), from December 2006 through July 31, 2011, in which paramedics, aided by electrocardiograph (ECG)-based decision support, randomized 911 (871 enrolled) patients (mean age, 63.6 years; 71.0% men) with high probability of ACS. INTERVENTION: Intravenous GIK solution (n = 411) or identical-appearing 5% glucose placebo (n = 460) administered by paramedics in the out-of-hospital setting and continued for 12 hours. MAIN OUTCOME MEASURES: The prespecified primary end point was progression of ACS to myocardial infarction (MI) within 24 hours, as assessed by biomarkers and ECG evidence. Prespecified secondary end points included survival at 30 days and a composite of prehospital or in-hospital cardiac arrest or in-hospital mortality, analyzed by intent-to-treat and by presentation with ST-segment elevation. RESULTS: There was no significant difference in the rate of progression to MI among patients who received GIK (n = 200; 48.7%) vs those who received placebo (n = 242; 52.6%) (odds ratio [OR], 0.88; 95% CI, 0.66-1.13; P = .28). Thirty-day mortality was 4.4% with GIK vs 6.1% with placebo (hazard ratio [HR], 0.72; 95% CI, 0.40-1.29; P = .27). The composite of cardiac arrest or in-hospital mortality occurred in 4.4% with GIK vs 8.7% with placebo (OR, 0.48; 95% CI, 0.27-0.85; P = .01). Among patients with ST-segment elevation (163 with GIK and 194 with placebo), progression to MI was 85.3% with GIK vs 88.7% with placebo (OR, 0.74; 95% CI, 0.40-1.38; P = .34); 30-day mortality was 4.9% with GIK vs 7.7% with placebo (HR, 0.63; 95% CI, 0.27-1.49; P = .29). The composite outcome of cardiac arrest or in-hospital mortality was 6.1% with GIK vs 14.4% with placebo (OR, 0.39; 95% CI, 0.18-0.82; P = .01). Serious adverse events occurred in 6.8% (n = 28) with GIK vs 8.9% (n = 41) with placebo (P = .26). CONCLUSIONS: Among patients with suspected ACS, out-of-hospital administration of intravenous GIK, compared with glucose placebo, did not reduce progression to MI. Compared with placebo, GIK administration was not associated with improvement in 30-day survival but was associated with lower rates of the composite outcome of cardiac arrest or in-hospital mortality. TRIAL REGISTRATION: clinicaltrials.gov Identifier: NCT00091507.


Asunto(s)
Síndrome Coronario Agudo/tratamiento farmacológico , Soluciones Cardiopléjicas/uso terapéutico , Infarto del Miocardio/prevención & control , Síndrome Coronario Agudo/mortalidad , Anciano , Técnicos Medios en Salud , Angina Inestable/complicaciones , Angina Inestable/tratamiento farmacológico , Técnicas de Apoyo para la Decisión , Método Doble Ciego , Electrocardiografía , Servicios Médicos de Urgencia , Femenino , Glucosa/uso terapéutico , Paro Cardíaco/prevención & control , Mortalidad Hospitalaria , Humanos , Insulina/uso terapéutico , Masculino , Persona de Mediana Edad , Infarto del Miocardio/etiología , Oportunidad Relativa , Potasio/uso terapéutico , Análisis de Supervivencia , Resultado del Tratamiento
5.
Pediatr Emerg Care ; 27(9): 812-25, 2011 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-21878829

RESUMEN

OBJECTIVES: The objectives of the study were to investigate the attitudes and practices of pediatric emergency department (PED) physicians (MDs), MD extenders (MD's assistants [PAs], nurse practitioners [NPs]), and nurses (RNs) regarding their counseling of alcohol-using adolescent PED patients and to determine which, if any, PED clinician characteristics predict current counseling practice. METHODS: An Internet-based survey of PED clinicians (MDs, PAs, NPs, and RNs) from 11 academic US PEDs was conducted. Respondents were asked about their counseling training, current counseling practices, confidence in their counseling skills, importance of counseling, attitudes and beliefs about counseling, and demographic information. Univariate and multivariate analyses were performed to determine the relationship between clinician characteristics and counseling practice. RESULTS: Counseling practice was strongly associated with one's profession; PED MDs/PAs/NPs reported significantly higher rates of counseling alcohol-using adolescents than PED RNs. These 2 groups differed significantly in terms of counseling training and experience. Counseling training and experience remained significant predictors of counseling practice, even after controlling for profession and other covariates. Both groups had similar views on the importance of counseling, confidence in their ability to counsel, and counseling substance-using adolescent PED patients. CONCLUSIONS: Pediatric ED MDs/PAs/NPs differ significantly from PED RNs in their counseling training, experience, and practice. These findings have important implications for the training and support necessary to successfully implement PED counseling. Specifically, formal training in counseling during professional schooling and garnering counseling experience after completing training may be critical factors in promoting PED counseling.


Asunto(s)
Conducta del Adolescente , Consumo de Bebidas Alcohólicas , Actitud del Personal de Salud , Cultura , Consejo Dirigido , Medicina de Emergencia , Conocimientos, Actitudes y Práctica en Salud , Enfermeras y Enfermeros/psicología , Enfermería Pediátrica , Pediatría , Médicos/psicología , Pautas de la Práctica en Medicina/estadística & datos numéricos , Centros Médicos Académicos , Adolescente , Recolección de Datos , Consejo Dirigido/organización & administración , Medicina de Emergencia/educación , Servicio de Urgencia en Hospital , Femenino , Promoción de la Salud/organización & administración , Humanos , Masculino , Rol de la Enfermera , Enfermeras y Enfermeros/estadística & datos numéricos , Educación del Paciente como Asunto/organización & administración , Enfermería Pediátrica/educación , Pediatría/educación , Rol del Médico , Médicos/estadística & datos numéricos , Estados Unidos
6.
Subst Abus ; 30(3): 223-9, 2009.
Artículo en Inglés | MEDLINE | ID: mdl-19591058

RESUMEN

Screening and brief intervention (SBI) for alcohol problems in the emergency department (ED) is effective. The objective of this study was to examine the translation of SBI into a busy community ED environment. The authors assessed key stakeholders views of SBI delivery model, then utilized feedback to adapt model. Adoption of SBI was recorded, with data collected on use of screening tool, and referral for a BI. Model was modified due to physicians' and nursing resistance; physicians only screened and a research assistant (RA) delivered the BI. When the RA was present, screening by ED staff increased from 50% to 71% but returned to 50% after the RA left. An identified opportunity was increased nursing interest after observation of SBI, with 15 nurses trained in SBI after ED intervention concluded. Important barriers to translating SBI to community ED clinical practice exist. However, with additional staff present, high levels of SBI can occur.


Asunto(s)
Alcoholismo/diagnóstico , Alcoholismo/terapia , Servicio de Urgencia en Hospital , Hospitales Comunitarios , Desarrollo de Programa/estadística & datos numéricos , Psicoterapia Breve/métodos , Actitud del Personal de Salud , Humanos
7.
Emerg Med Clin North Am ; 24(4): 925-67, 2006 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-16982347

RESUMEN

Alcohol, tobacco, and other drug use is a significant societal problem. Individuals who use these substances are frequently seen in emergency departments at rates disproportionately greater than their population prevalence. This article highlights the impact of these drugs on patients and on emergency departments, including common presenting problems of individuals on these substances. Also discussed is how to help and to refer individuals with substance abuse problems through brief motivational interventions.


Asunto(s)
Consumo de Bebidas Alcohólicas/epidemiología , Servicio de Urgencia en Hospital/estadística & datos numéricos , Fumar/epidemiología , Trastornos Relacionados con Sustancias/epidemiología , Adolescente , Conducta del Adolescente , Adulto , Consumo de Bebidas Alcohólicas/efectos adversos , Consumo de Bebidas Alcohólicas/economía , Niño , Promoción de la Salud , Humanos , Rol del Médico , Prevalencia , Factores de Riesgo , Fumar/efectos adversos , Prevención del Hábito de Fumar , Trastornos Relacionados con Sustancias/economía , Trastornos Relacionados con Sustancias/prevención & control , Estados Unidos/epidemiología
8.
J Stud Alcohol ; 66(3): 433-7, 2005 May.
Artículo en Inglés | MEDLINE | ID: mdl-16047535

RESUMEN

OBJECTIVE: Although the Short Index of Problems (SIP) is often used, little is known about the psychometric properties of the SIP in special populations. The present study seeks to determine the following: (1) whether it is possible to substitute items to enhance the psychometric properties of the SIP and (2) whether the SIP, or improved scale, is as sensitive as the Drinker Inventory of Consequences (DrInC) to assess intervention effectiveness. METHOD: The sample consisted of 404 injured patients who were treated in the Emergency Department (ED) of a major teaching hospital that serves southern New England. Three approaches were used to guide development of the 3-month SIP-R, the potential alternative to the SIP. Cronbach's alpha assessed intrascale reliability; hierarchical multiple regression assessed construct validity; performance of the scales assessing intervention change were compared to the total 3-month DrInC as a function of intervention using analysis of covariance (ANCOVA). RESULTS: There was no evidence that changing the current SIP items will significantly improve performance. The 3-month SIP performed as well as the 3-month DrInC-2R in predicting 12-month DrInC scores and in determining intervention change at 12 months. Of the 45 DrInC items, 31 also predicted a difference across intervention groups. CONCLUSIONS: These results suggest there is no advantage to changing the current SIP items. The 3-month SIP is a psychometrically sound measure for assessing consequences of alcohol consumption in an ED sample and is almost as sensitive to intervention change as the full DrInC.


Asunto(s)
Alcoholismo , Servicios Médicos de Urgencia , Encuestas y Cuestionarios , Heridas y Lesiones/diagnóstico , Heridas y Lesiones/epidemiología , Adulto , Alcoholismo/diagnóstico , Alcoholismo/epidemiología , Alcoholismo/rehabilitación , Femenino , Humanos , Masculino , Psicometría , Reproducibilidad de los Resultados
9.
Acad Emerg Med ; 11(8): 859-66, 2004 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-15289193

RESUMEN

Many published clinical trials have less than adequate follow-up. When conducting a clinical trial, researchers attempt to minimize data loss; however, some data may not be collected, particularly when subjects are lost to follow-up. Careful planning of research protocols, including comprehensive initial data collection, identification of locators, flexible scheduling, systematic subject tracking, monitoring subject loss, and systematically approaching problem cases can ensure high follow-up rates. This article presents a compendium of techniques and procedures that researchers can use to enhance follow-up and address attrition in their studies. Finally, this article outlines statistical techniques that can be used to address the effects of missing data, particularly when patients are lost to follow-up.


Asunto(s)
Ensayos Clínicos como Asunto/métodos , Medicina de Emergencia/métodos , Estudios de Seguimiento , Negativa a Participar , Sujetos de Investigación , Citas y Horarios , Ensayos Clínicos como Asunto/normas , Interpretación Estadística de Datos , Humanos , Entrevistas como Asunto/métodos , Relaciones Profesional-Paciente , Reproducibilidad de los Resultados
10.
JAMA ; 288(21): 2693-700, 2002 Dec 04.
Artículo en Inglés | MEDLINE | ID: mdl-12460092

RESUMEN

CONTEXT: Observational studies of acute myocardial perfusion imaging in emergency department (ED) patients with chest pain have suggested high sensitivity and negative predictive value for acute cardiac ischemia, but use of this method has not been prospectively tested. OBJECTIVE: To assess whether incorporating acute resting perfusion imaging into an ED evaluation strategy for patients with suspected acute ischemia but no initial electrocardiogram (ECG) changes diagnostic of acute ischemia improves clinical decision making for initial ED triage. DESIGN, SETTING, AND PATIENTS: Prospective, randomized controlled trial conducted at 7 academic medical centers and community hospitals between July 1997 and May 1999 among 2475 adult ED patients with chest pain or other symptoms suggestive of acute cardiac ischemia and with normal or nondiagnostic initial ECG results. INTERVENTION: Patients were randomly assigned to receive either the usual ED evaluation strategy (n = 1260) or the usual strategy supplemented with results from acute resting myocardial perfusion imaging using single-photon emission computed tomography with injection of 20 to 30 mCi of Tc-99m sestamibi (n = 1215), interpreted in real time by local staff physicians and with results provided to the ED physician for incorporation into clinical decision making. MAIN OUTCOME MEASURE: Appropriateness of triage decision either to admit to hospital/observation or to discharge directly home from the ED. RESULTS: Among patients with acute cardiac ischemia (ie, acute myocardial infarction [MI] or unstable angina; n = 329), there were no differences in ED triage decisions between those receiving standard evaluation and those whose evaluation was supplemented by a sestamibi scan. Among patients with acute MI (n = 56), 97% vs 96% were hospitalized (relative risk [RR], 1.00; 95% confidence interval [CI], 0.89-1.12), and among those with unstable angina (n = 273), 83% vs 81% were hospitalized (RR, 0.98; 95% CI, 0.87-1.10). However, among patients without acute cardiac ischemia (n = 2146), hospitalization was 52% with usual care vs 42% with sestamibi imaging (RR, 0.84; 95% CI, 0.77-0.92). CONCLUSIONS: Sestamibi perfusion imaging improves ED triage decision making for patients with symptoms suggestive of acute cardiac ischemia without obvious abnormalities on initial ECG. In this study, unnecessary hospitalizations were reduced among patients without acute ischemia, without reducing appropriate admission for patients with acute ischemia.


Asunto(s)
Isquemia Miocárdica/diagnóstico por imagen , Tomografía Computarizada de Emisión de Fotón Único , Triaje , Enfermedad Aguda , Angina Inestable/diagnóstico , Angina Inestable/diagnóstico por imagen , Electrocardiografía , Servicio de Urgencia en Hospital , Femenino , Hospitalización/estadística & datos numéricos , Humanos , Masculino , Persona de Mediana Edad , Infarto del Miocardio/diagnóstico , Infarto del Miocardio/diagnóstico por imagen , Isquemia Miocárdica/diagnóstico , Evaluación de Procesos y Resultados en Atención de Salud , Alta del Paciente/estadística & datos numéricos , Estudios Prospectivos , Radiofármacos , Tecnecio Tc 99m Sestamibi
11.
J Emerg Med ; 22(4): 335-40, 2002 May.
Artículo en Inglés | MEDLINE | ID: mdl-12113840

RESUMEN

To compare the "Bellows on Sternum Resuscitation" (BSR) device that permits simultaneous compression and ventilation by one rescuer with two person cardiopulmonary resuscitation (CPR) with bag-valve-mask (BVM) ventilation in a single blind crossover study performed in the laboratory setting. Tidal volume and compression depth were recorded continuously during 12-min CPR sessions with the BSR device and two person CPR. Six CPR instructors performed a total of 1,894 ventilations and 10,532 compressions in 3 separate 12-min sessions. Mean tidal volume (MTV) and compression rate (CR) with the BSR device differed significantly from CPR with the BVM group (1242 mL vs. 1065 mL, respectively, p = 0.0018 and 63.2 compressions per minute (cpm) vs. 81.3 cpm, respectively, p = 0.0076). Error in compression depth (ECD) rate of 9.78% was observed with the BSR device compared to 8.49% with BMV CPR (p = 0.1815). Error rate was significantly greater during the second half of CPR sessions for both BSR and BVM groups. It is concluded that one-person CPR with the BSR device is equivalent to two-person CPR with BVM in all measured parameters except for CR. Both groups exhibited greater error rate in CPR performance in the latter half of 12-min CPR sessions.


Asunto(s)
Reanimación Cardiopulmonar/instrumentación , Reanimación Cardiopulmonar/métodos , Auxiliares de Urgencia , Paro Cardíaco/terapia , Humanos , Maniquíes , Volumen de Ventilación Pulmonar/fisiología
SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA
...