A case of multiple thrombosis and septic shock in a critically ill patient with Omicron infection.

The emergence of the acute respiratory syndrome coronavirus 2 variant named Omicron has become a global concern. A 74-year-old unvaccinated patient was critically ill infected with the Omicron variant characterised by septic shock, large-scale cerebral embolism, deep vein thrombosis, and multiple organ dysfunction with respiratory failure, acute renal failure, coagulation dysfunction. The clinical symptoms were successfully controlled by active rescue treatment such as anti-infection, anti-shock, implantation of a vena cava filter as well as multi-organ function support. Although there are many complications in critically ill patients with Omicron variant infections, especially coagulation disorders and thrombosis, they can be resolved with a combination of Chinese and Western medicine positive rescue.

State Anxiety Down-Regulates Empathic Responses: Electrophysiological Evidence.

State anxiety is common in our life and has a significant impact on our emotion, cognition and behavior. Previous studies demonstrate that people in a negative mood are associated with low sympathy and high personal distress. However, it is unknown how state anxiety regulates empathic responses so far. Here, we recorded event-related brain potentials (ERP) from the experimental group who were in state anxiety and the control group when they were watching painful and neutral pictures. Participants in the experimental group and the control group were asked to do the same mental arithmetic problems. The only difference was that the experimental group had time restriction and was evaluated by the observer. The results showed that no significant N2 differentiation between painful and neutral stimuli was found in both groups. In contrast, LPP amplitudes induced by painful stimuli were significantly larger than that of neutral stimuli in the control group, but not in the experimental group. Our results indicate that state anxiety inhibit empathic responses from the early emotional sharing stage to the late cognitive evaluation stage. It provides neuroscientific evidence that one's own emotional state will have an important impact on empathy.