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J Ethnopharmacol ; 64(1): 23-34, 1999 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-10075119

RESUMEN

The medicinal system of the Asháninka Indians in Perú is portrayed. Three categories of medical disorders and healers are recognized. A human is viewed to consist of a physical and a spiritual being who communicate with each other by means of a regulating element. The significance of Uncaria tomentosa (Willd.) DC. (Rubiaceae), locally known as unã de gato, in traditional medicine is emphasized by its exclusive use by priests to influence this regulation. Pharmacological and toxicological results obtained with extracts or isolated compounds are summarized. Pentacyclic oxindole alkaloids stimulate endothelial cells in vitro to produce a lymphocyte-proliferation-regulating factor. Tetracyclic oxindole alkaloids act as antagonists. A significant normalization of lymphocyte percentage was observed in vivo although total leucocyte numbers did not change.


Asunto(s)
Alcaloides/farmacología , Linfocitos/efectos de los fármacos , Medicina Tradicional , Plantas Medicinales , Adulto , Alcaloides/uso terapéutico , Animales , Línea Celular/efectos de los fármacos , Femenino , Infecciones por VIH/tratamiento farmacológico , Humanos , Indígenas Sudamericanos , Activación de Linfocitos/efectos de los fármacos , Masculino , Ratones , Perú , Extractos Vegetales/farmacología , Extractos Vegetales/uso terapéutico , Ratas , Ratas Wistar
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