Tianxia120: A Multimodal Medical Data Collection Bioinformatic System for Proactive Health Management in Internet of Medical Things.

A digital medical health system named Tianxia120 that can provide patients and hospitals with "one-step service" is proposed in this paper. Evolving from the techniques of Internet of Medical Things (IoMT), medical dig data, and medical Artificial Intelligence, the system can systematically promote the change of service status between doctors and patients from "passive mode" to "proactive mode" and realize online service that is similar to offline medical treatment scenarios. The system consists of a patient terminal and a doctor terminal. They can perform online inquiry (through graphic, voice, telephone, video, etc.), electronic prescription, multiparameter self-diagnosis, cold chain logistics, medicine distribution, etc. The system can provide rich medical health information, medical tools browsing, and health care big data aggregation processing functions. Compared with the traditional medical system, this system has the characteristics of full function, rich data, and high security. It is expected to be applied to hospital applications and medical research to promote the construction and innovation of clinical medical disciplines.

The design of a wide bandwidth time marker generator.

The Time Marker Generator (TMG) is an important instrument that is used to calibrate the time base of an oscilloscope. If a direct digital frequency synthesizer is used to generate the necessary waveforms, there is serious distortion in the generated square wave when the ratio of the sampling frequency to the output frequency is non-integer. In addition, the look-up table (LUT) in the direct digital waveform synthesizer needs a large storage capacity to generate a narrow triangular wave at a low output frequency. This paper proposes a design that will generate the time marker whose samples are synthesized by real-time calculation instead of storing them in a LUT. We also propose an M waveform data synthesizer with a parallel structure (M-WDSPS) to reduce the operating clock frequency of the field programmable gate array (FPGA). We built a 4-WDSPS TMG based on this design and reduced the required clock frequency from 1 GHz to 250 MHz, thus making the implementation possible in an FPGA. Our proposed TMG design can provide square wave, pulse wave, narrow triangular wave, and linear triangular wave with different amplitudes in two operating modes: normal mode and highlight mode. The TMG we constructed can provide the time marker with an output frequency range from 10 mHz to 111 MHz, a rising/falling edge time lower than 1 ns, regardless of whether the output frequency is low or high, and a frequency stability lower than 0.1 ppm.

Precisely synchronous and cascadable multi-channel arbitrary waveform generator.

The output bandwidth and the capability to generate multiple analog outputs with accurately adjustable relative phase are important specifications of arbitrary waveform generator (AWG). To increase the output bandwidth, AWG with a multi-memory paralleled direct digital synthesizer structure (DDS) was proposed to break through operating speed limitations of memory and field programmable gate array. But this structure does complicate synchronization of the analog outputs. This paper proposes a structure for synchronization of the outputs of multi-channel high speed AWG that generates arbitrary waveforms using a multi-memory paralleled DDS. Careful distribution of the clock and trigger signals enables elimination of the random initial phase caused by the frequency divider. Based on this structure, a four-channel 600 mega samples per second AWG is designed. An embedded clock synchronization calibration module is designed to eliminate the random phase difference caused by a frequency divider inside a digital-to-analog converter. The AWG provides a 240 MHz bandwidth, 16 mega-samples storage depth, inter-channel initial skew accuracy less than 150 ps, and 0.0001° phase resolution, which can be used to generate two pairs of I/Q signals or a pair of differential I/Q signals for the quadrature modulator. Additionally, more AWGs can be cascaded to obtain more output channels with an output timing skew between adjacent channels of less than 1.6 ns.