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Drug Deliv ; 22(3): 258-65, 2015 May.
Artículo en Inglés | MEDLINE | ID: mdl-24611941

RESUMEN

Targeting drug system (TDS) or targeted drug delivery system (TDDS) is a new kind of drug delivery system which could make drug to be directly concentrated on the target site with high curative effects and low side-effects. As the quintessence of Chinese culture, traditional Chinese medicine (TCM) has a large advantage in many disease clinical treatments, especially in cancer, hypertension and many other intractable diseases owing to their low toxicity and side-effects relative to western medicine. This article reviews literatures on development of TCM-targeted preparations which were published in the past 10 years. TDS including active-targeting, passive-targeting and physical-chemical-targeting preparations were introduced through domestic and overseas literatures to reveal the unique advantages of TCM-targeting preparations in drug delivery system. In this article, we have reviewed some kinds of TCM-targeting preparations and indicated that great attention should be paid to the research on the TCM-targeting preparations.


Asunto(s)
Sistemas de Liberación de Medicamentos/métodos , Medicamentos Herbarios Chinos/administración & dosificación , Medicamentos Herbarios Chinos/farmacocinética , Transporte Biológico , Portadores de Fármacos/química , Sistemas de Liberación de Medicamentos/tendencias , Emulsiones , Humanos , Liposomas , Microesferas , Nanopartículas , Tamaño de la Partícula , Propiedades de Superficie
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