RESUMEN
In the title compound, C27H27BrFNO4, which is an inhibitor of acetyl-CoA carboxyl-ase, the cyclo-hexane ring displays a chair comformation with the spiro-C and meth-oxy-bearing C atoms deviating by 0.681â (7) and -0.655â (1)â Å, resppectively, from the mean plane formed by the other four C atoms of the spiro-C6 ring. The mean planes of the cyclo-hexane and 2-bromo-4-fluoro-phenyl rings are nearly perpendicular to that of the pyrrolidine ring, making dihedral angles 89.75â (6) and 87.60â (9)°, respectively. In the crystal, mol-ecules are linked via pairs of N-Hâ¯O hydrogen bonds, forming inversion dimers.
RESUMEN
In the title compound, C18H23NO3, the cyclo-hexane ring has a chair conformation. The oxirane plane (OCC) makes a dihedral angle of 76.15â (13)° with that of the pyrrolidine ring to which it is fused. The mean plane of the cyclo-hexane ring and the benzene ring are almost normal to the pyrrolidine ring, with dihedral angles of 88.47â (8) and 77.85â (8)°, respectively. In the crystal, mol-ecules are linked via pairs of N-Hâ¯O hydrogen bonds, forming inversion dimers. These dimers are linked via pairs of C-Hâ¯O hydrogen bonds, forming chains along the a-axis direction.