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1.
Soc Sci Med ; 340: 116405, 2024 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-37992614

RESUMEN

Health disparities based on racial status are well-researched by social scientists, but this field of knowledge has rarely been investigated beyond the Western context. As the largest province in China, Xinjiang has over 50% non-Han populace-and this group is subjected to various forms of inequalities. The current study is the first to quantitatively demonstrate the disparity in mortality between the Han majority and Turkic minority in Xinjiang. We have developed a theory-driven framework to approach race as a fundamental cause of mortality disparity through both individual and context-level pathways that trigger the proximate determinants of death. We compiled the 2015 China Microcensus with the Sixth Decennial Census (2010) and web-extracted point-of-interest information for data at different ecological levels. The results reveal that the mortality rate is significantly pronounced for Turks at the county-level and Turks' death incidence is elevated at the household level. The inclusion of variables at the individual- and context-level explains about 38% of the mortality disparity between Han and Turks, but the significant disparity remains strong after considering the covariates, the "healthy migrant" scenario, geographical clustering, and exposure risk. We cautiously suggest the remaining unexplained portion of the mortality disparity may be due to unobserved racial inequity and urge the academic community to further investigate this underexplored subject.


Asunto(s)
Disparidades en el Estado de Salud , Mortalidad , Humanos , Incidencia , Grupos Minoritarios , China
2.
Nicotine Tob Res ; 26(6): 685-691, 2024 May 22.
Artículo en Inglés | MEDLINE | ID: mdl-38127442

RESUMEN

INTRODUCTION: Exposure to secondhand smoke (SHS) among women is prevalent in China which increases their risk of developing a wide range of diseases and can affect their susceptibility to adverse reproductive health effects. This study aims to examine the association between SHS exposure among women and the adoption and implementation of tobacco control measures on campus in China. AIMS AND METHODS: 7469 female college students who have never smoked were recruited from 50 universities across China using a multistage sampling technique. All participants reported their exposure to SHS and the tobacco advertising and promotion on campus. Participants from colleges with smoke-free policies reported the implementation of smoke-free policies on campus measured by: (1) no evidence of smoking and (2) the display of smoke-free signs in public places. Multivariate logistic regression models were applied using weighted survey data. RESULTS: SHS exposure among participants was 50.5% (95% CI = 44.2% to 56.9%). The adoption of a smoke-free policy was not associated with SHS exposure (OR: 1.01, 95% CI = .71, 1.42), however, the implementation of the policy was significantly negatively associated with SHS exposure (OR: 0.56, 95% CI = .47 to 0.67). In addition, tobacco advertising and promotion on campus were significantly positively associated with SHS exposure (OR: 2.33, 95% CI = 1.42, 3.82; OR: 1.52; 95% CI = 1.15, 2.02, respectively). CONCLUSIONS: Exposure to SHS is prevalent among female college students in China. Successful implementation of a smoke-free policy and banning tobacco advertising and promotion on campus could be effective measures to protect young women from the harms of SHS in China. IMPLICATIONS: Approximately half of female college students are exposed to SHS on campus in China. Failure to implement smoke-free policies and exposure to tobacco marketing on campus are associated with higher SHS exposure. To protect millions of young Chinese women from the health harms of SHS, universities need to enact and enforce smoke-free policies within campus boundaries and adopt comprehensive bans on tobacco advertising and promotion on campus.


Asunto(s)
Estudiantes , Contaminación por Humo de Tabaco , Humanos , Contaminación por Humo de Tabaco/prevención & control , Femenino , Universidades , China/epidemiología , Estudios Transversales , Adulto Joven , Estudiantes/estadística & datos numéricos , Adulto , Política para Fumadores/legislación & jurisprudencia , Publicidad/estadística & datos numéricos , Publicidad/legislación & jurisprudencia , Publicidad/métodos , Adolescente , Control del Tabaco
3.
Children (Basel) ; 10(3)2023 Mar 02.
Artículo en Inglés | MEDLINE | ID: mdl-36980053

RESUMEN

RATIONALE: Children's health is conventionally studied as an ultimate consequence resulting from various social and biological processes that jointly channel the risk factors and pathogens toward an individual health outcome. What is currently neglected is the rich tradition of a functionalist analysis of children's health as a necessary function in the family institution. Children's health may be associated with how children are integrated into the family's core functioning and how parents regulate children's behaviors. METHODS: The current study used a cross-sectional sample of 891 parents from 2018 southern Jiangsu and surveyed information about children's health and family activities. Employing a latent class analysis, we established four types of families based on children's integration and parental regulation: loose, free, pressed, and concerted. RESULTS: The regression results showed that a child's health is associated with the concerted family type (OR = 3.6, p < 0.05), indicating the necessary functionality of health in heavily regulated and mobilized families. CONCLUSION: This study broadens the perspective on children's health by ushering back functionalism and placing health in its social implications.

4.
Nicotine Tob Res ; 25(2): 237-246, 2023 01 05.
Artículo en Inglés | MEDLINE | ID: mdl-35182425

RESUMEN

INTRODUCTION: Prior studies on the association between the intensity of and motives for vaping e-cigarettes have highlighted the psychological dynamics of motivational changes, but less about how vaping motives may shift as a function of risk perceptions exacerbated by unanticipated events. This study frames the COVID-19 pandemic as an exacerbating threat to pulmonary health, and tests how e-cigarette users' risk perceptions of COVID-19 are related to different motives for vaping and ultimately the intensity of e-cigarette use. AIMS AND METHODS: An online survey of e-cigarette users in the United States (n = 562) was conducted during April 2020 when much of the United States was under "lockdown" conditions. We distinguished three types of vaping motives (health, socialization, and dependence) and established the classification with confirmatory factor analysis. Structural equation modeling was conducted for path analyses and mediation tests. RESULTS: All three vaping motives were significantly associated with greater use intensity. A heightened risk perception of e-cigarette users' vulnerability to COVID-19 was inversely associated with use intensity (-.18, p < .01) and health motives for vaping (-.27, p < .001), but not associated with socialization and dependence motivations. Health motives for vaping mediated 35% of the association between COVID-19 risk perceptions and use intensity. CONCLUSIONS: Our findings indicate that risk perceptions of exacerbated threats may reduce e-cigarette use directly, and also indirectly through shifting certain types of motivations for vaping. Beyond elucidating the relational dynamics between vaping psychology and health risks, these results also indicate health professionals may leverage the pandemic to promote nicotine cessation or reduced use. IMPLICATION: Little is known about how vaping motives shift after unanticipated events such as pandemics. This study contributes to knowledge of how the use of e-cigarettes is motivated by different dimensions of rationales and exogenous risks. Exploiting the emergence of the COVID-19 pandemic, we found risk perceptions are associated with the intensity of e-cigarette use indirectly specifically through health motivations. Risk perceptions are not associated with socialization and dependence motives for vaping.


Asunto(s)
COVID-19 , Sistemas Electrónicos de Liberación de Nicotina , Vapeo , Humanos , Estados Unidos/epidemiología , Vapeo/psicología , Pandemias , Motivación , COVID-19/epidemiología , Percepción
5.
Artículo en Inglés | MEDLINE | ID: mdl-36430051

RESUMEN

This study aims to investigate e-cigarette and tea cigarette gifting in China and their influencing factors, as well as to explore whether they were associated with tobacco use and cessation. Using a multistage sampling design, 1512 household heads from Guangdong and Shaanxi provinces were recruited for the study and filled out an online questionnaire about smoking status, social participation, e-cigarette, and tea cigarette gifting. Results showed that more than 30% and nearly 3% of participants had been gifted tea cigarettes and e-cigarettes, respectively. Marital status, province of residence, smoking status, and social participation were associated with gifting behaviors. Logistic regressions showed that receiving e-cigarettes (OR = 3.43, p < 0.05) and tea cigarettes (OR = 1.70, p < 0.01) were related to tobacco use. Smokers who have received e-cigarettes (OR = 9.85, p < 0.01) and tea cigarettes (OR = 1.92, p < 0.05) were also less likely to quit smoking.


Asunto(s)
Sistemas Electrónicos de Liberación de Nicotina , Productos de Tabaco , Humanos , Uso de Tabaco , China/epidemiología ,
6.
Health Sociol Rev ; 31(3): 309-325, 2022 11.
Artículo en Inglés | MEDLINE | ID: mdl-35514070

RESUMEN

The widespread exchange of tobacco cigarettes as a gift in some societies normalises the symbolic desirability of tobacco products and promotes smoking. Little is known about how and why people exchange toxic substances as gifts. This study argues two key factors involved in social exchange processes - reciprocity and social capital - can explain gift cigarette circulation. We conducted a multistage survey among household heads from China and measured the quantity and monetary values of outgoing and incoming gift cigarettes circulated by each household and measured social capital in three dimensions: collective participation, social ties, and trust. Ordinary Least Square regressions showed that reciprocity is strongly and significantly associated with both the value and quantity of gift cigarettes. All three dimensions of social capital are varyingly associated with gifting cigarettes. Income and higher classes are also associated with greater quantity and value of received cigarettes. This study broadens the phenomenon of gifting cigarettes to the more universal patterns of reciprocity and social capital, wherein better social capital and socioeconomic position ironically lead to a higher risk of tobacco use and endanger health. We suggest policymakers target the endemic social need for gift exchange in China's informal economy.


Asunto(s)
Capital Social , Productos de Tabaco , China/epidemiología , Donaciones , Humanos , Fumar/epidemiología
7.
J Gerontol Soc Work ; 65(7): 692-710, 2022 10.
Artículo en Inglés | MEDLINE | ID: mdl-34985409

RESUMEN

Caregiving burden proves to be a risk factor of anxiety disorders and anxiety affection. The current study investigates how an endogenous personality dimension - neuroticism - moderates the association between caregiving burden and anxiety affection. Between 2015 and 2017, the study deployed a cross-sectional survey of 674 (response rate = 89%) older adults who were hospitalized for dementia at two hospitals. From all primary caregivers of these patients, 661 agreed to participate in the survey which yielded 661 matched dyads as the final sample. Caregiving burden, neuroticism, and anxiety affection were each measured by established assessment instruments. We employed multivariate OLS regression to test the moderator and regressor effects. We found that care burden is a significant risk factor of higher levels of anxiety affection (ß = .17, p < .001), and accounts for 4.6% of the variance in anxiety. Neurotic personality is also significantly associated with a greater level of anxiety (ß = .26, p < .001). Neurotic personality moderates the association between anxiety and care burden (ß = .24, p < .001). Our findings suggest that social and healthcare workers should assess caregiver personality and burden as well as provide support, resources, and coping strategies to those with neurotic personality traits or high care burden in an effort to reduce anxiety among caregivers.


Asunto(s)
Cuidadores , Demencia , Anciano , Ansiedad/complicaciones , Trastornos de Ansiedad/complicaciones , Carga del Cuidador , Estudios Transversales , Demencia/complicaciones , Humanos , Neuroticismo
8.
Am J Health Behav ; 45(6): 1002-1015, 2021 11 15.
Artículo en Inglés | MEDLINE | ID: mdl-34969412

RESUMEN

OBJECTIVES: We examined associations between excessive WeChat use and mental disorders at the individual and contextual level. METHODS: We conducted a representative nationwide survey sampling process of 11,283 medical students from 30 universities in China. Mental health status was measured by the Chinese Health Questionnaire. Both unadjusted and adjusted methods were considered in the analyses. RESULTS: High frequency and long-time use prevalence was 19.1% and 31.2% respectively among WeChat users. The multilevel logistic regression model found that individual-level high frequency (OR = 1.26) and long-time use (OR = 1.24) were significantly associated with mental health disorders. University-level excessive WeChat use also was associated with the mental disorders (OR = 1.33 [high frequency use]; OR = 1.17 [long-time use]). Structural equation analysis showed that individual- and university-level high frequency and individual-level and university-level long-time WeChat use have a direct influence on poor mental health. The above variables, except individual-level long-time use, have an indirect influence on poor mental health through mental stress. CONCLUSIONS: This study provides new evidence that excessive WeChat use is associated with mental disorders. These findings underscore the importance of alerting people to the possible health risks of excessive social media use.


Asunto(s)
Trastornos Mentales , Estrés Psicológico , China/epidemiología , Humanos , Trastornos Mentales/epidemiología , Estrés Psicológico/epidemiología , Encuestas y Cuestionarios , Universidades
9.
Health Qual Life Outcomes ; 19(1): 156, 2021 May 28.
Artículo en Inglés | MEDLINE | ID: mdl-34049560

RESUMEN

BACKGROUND: As China's aging trend intensifies and the proportion of empty nests increases, the health-related quality of life of the elderly is the focus of social attention. Previous studies focused on the quality of life of the elderly, rather than empty nesters, and lacked the discussion of the mechanism of influencing factors. Thus, this study aimed to explore the influencing factors of the quality of life (QOL) and interaction mechanisms among empty nesters in Shanxi Province, China, so as to provide practical reference for improving the QOL of empty nesters. METHODS: A total of 4901 empty nesters in Shanxi Province, China, were selected using multi-stage random cluster sampling method in this cross-sectional study. The quality of life was assessed with the Short Form 36 Health Survey (SF-36). Multiple linear regression analysis (stepwise) was performed to examine the factor associated with QOL. Structural equation model (SEM) approach was conducted to test the direct and indirect association between QOL influencing factors with QOL. RESULTS: The average QOL score of empty nesters was 63.34 (SD = 17.23). The multiple linear regression revealed that gender, age, education, monthly income, drinking status, exercise frequency, physical examination frequency, attention to daily nutritional health, relationship with a spouse and relationship with children were significant predictors of the empty nester's QOL (P < 0.05) (R2 = 0.128). SEM showed that behavioral lifestyle had a direct effect on QOL (ß = 0.446, P < 0.001). Socio-economic status had an indirect effect (ß = 0.288, P < 0.001) on QOL through behavioral lifestyle. The family relationship had an indirect effect (ß = 0.115, P < 0.001) on QOL. CONCLUSION: Behavioral lifestyle was the strongest influencing factor in the quality of life among empty nesters, followed by socio-economic status and family relationships. Thus, maintaining a healthy behavioral lifestyle was important to improve the QOL of the empty nesters. Our findings provide a concrete and strong reference for the formulation of targeted intervention strategies.


Asunto(s)
Adaptación Psicológica , Estilo de Vida Saludable , Relaciones Padres-Hijo , Padres/psicología , Calidad de Vida/psicología , Clase Social , Anciano , Anciano de 80 o más Años , China , Estudios Transversales , Femenino , Humanos , Masculino , Persona de Mediana Edad , Análisis de Regresión , Encuestas y Cuestionarios
10.
Am J Health Behav ; 45(2): 334-341, 2021 03 01.
Artículo en Inglés | MEDLINE | ID: mdl-33888193

RESUMEN

Objectives: We examined changing trends of uncertainty stress, and its impact on disease fear and prevention behaviors during the Chinese COVID-19 epidemic, using a prospective observational study. Methods: We employed a longitudinal design. We recruited participants for an online panel survey from chat groups on social media platforms. There were 5 waves of interviews. Information on uncertainty stress and related variables were collected via the online survey. Descriptive statistics and the GIM program were used for data analysis. Results: Participants numbered 150 for the linkable baseline survey and 102 (68%) for the final survey. Uncertainty stress (ß = -.047, SE = .118, p > .05) did not show a statistically significant temporal change trend over the observation period. Disease fear manifested a statistically significant downwards trend (ß = -.342, SE = .157, p < .05), and prevention behaviors indicated an upwards trend (ß = .048, SE = .021, p < .05) during the observation period. Uncertainty stress was positively associated with disease fear (ß = .45046, SE = .05964, p < .001), and negatively associated with self-efficacy (ß = -.6698, SE = .01035, p < .001), and prevention behaviors (ß = -.02029, SE = .00876, p =.021). Conclusion: This study yielded new information about uncertainty stress among Chinese people during the COVID-19 epidemic. Policy changes and public education are essential for minimizing the negative effects of uncertainty stress in disease prevention.


Asunto(s)
COVID-19/prevención & control , COVID-19/psicología , Miedo , Estrés Psicológico , Incertidumbre , Adulto , Femenino , Humanos , Entrevistas como Asunto , Masculino , Persona de Mediana Edad , Estudios Prospectivos , Investigación Cualitativa , SARS-CoV-2 , Encuestas y Cuestionarios
11.
Tob Induc Dis ; 19: 21, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-33767605

RESUMEN

INTRODUCTION: Social deprivation is a known determinant of health and related behaviors. Many studies have linked socioeconomic factors to secondhand smoke (SHS) exposure. However, no studies have examined the relationship between social deprivation and SHS exposure. This study examined whether contextual social deprivation - variously based on living in a house without a car, that was overcrowded, or had an unemployed member (s) - had an independent association with SHS exposure at both individual and regional levels among Chinese residents. METHODS: A cross-sectional multistage sampling design was utilized to interview subjects from 6 selected cities in China. A standardized questionnaire selected sociodemographic characteristics, contextual social deprivation and SHS exposure. Multilevel logistic regression models were used to assess the association between social deprivation and SHS exposure. RESULTS: A total of 5782 valid questionnaires were collected in this study. Among 2930 non-smokers, the SHS exposure prevalence was 21.9% (95% CI: 19.5- 24.30). Multilevel logistic regression showed a negative association between household income, regional GDP, and SHS exposure, respectively, and positive associations between contextual social deprivation and SHS exposure. CONCLUSIONS: Findings support the central proposition that contextual social deprivation must be factored into SHS exposure messages. Our research underscores the importance of reducing health inequality in controlling SHS exposure.

12.
Health Educ Res ; 36(2): 151-158, 2021 04 12.
Artículo en Inglés | MEDLINE | ID: mdl-33724361

RESUMEN

This prospective observational study examined changing trends in mental and behavioral responses, and their association with perceived risk, severity, self-efficacy and isolation status during the Chinese COVID-19 epidemic. There were five waves of interviews. Descriptive statistics and non-parametric test methods were used for data analysis. Participants numbered 150 for the linkable baseline survey and 102 completed all 5 survey waves and were included in the analysis. Mental stress, emotional status and lifestyle manifested a statistically significant downwards trend across the total period of this panel study. The number of reported new confirmed patients perceived high risk and perceived severity were positively associated with mental stress, emotional status and lifestyle. Self-efficacy was negatively associated with each type of mental and behavioral response. The more time people were confined to their home, the more serious the emotional and lifestyle problems. Dose-response relationships were noted between the number of reported new confirmed patients and mental stress, emotional status and lifestyle during the five observation points. This study yielded new information about mental and behavioral responses among Chinese people during the COVID-19 epidemic. Policy changes and health education are essential for minimizing the adverse health effects of these responses.


Asunto(s)
COVID-19/psicología , Salud Mental , Adulto , Ansiedad , China/epidemiología , Estudios Transversales , Femenino , Humanos , Estilo de Vida , Masculino , Persona de Mediana Edad , Pandemias , Medición de Riesgo , Autoeficacia , Aislamiento Social , Estrés Psicológico , Encuestas y Cuestionarios
13.
Am J Health Promot ; 35(7): 977-983, 2021 09.
Artículo en Inglés | MEDLINE | ID: mdl-33787350

RESUMEN

PURPOSE: To investigate perceived beliefs, uncertainty, and behavioral responses among Chinese residents toward the COVID-19 outbreak, and explore their relationships amid an incipient pandemic. DESIGN: A cross-sectional correlational survey with a combination of a convenience and snowball sampling design. SETTING: This study was conducted online from February 7 to 14, 2020, the third week after the lockdown of Wuhan city on January 23. PARTICIPANTS: A total of 2,654 residents was contacted, 2,534 agreed to participate, and 2,215 completed valid questionnaires. The sample covered 30 provinces, municipalities, autonomous regions of China, and a broader region. MEASURES: The Uncertainty About COVID-19 Scale was applied to assess perceived public uncertainty. Five dimensions of health beliefs about COVID-19 and 12 health-related response behaviors were measured. ANALYSIS: Univariate analysis and multiple linear regression models were used to identify associations. Mediation was assessed by a bootstrapping technique. RESULTS: Five constructs of health beliefs were found to be significant predictors of multiple response behaviors. Uncertainty about COVID-19 has a direct relationship with general response behaviors (ß=-0.119**) and sanitization practices (ß=-0.068**). Emergency coping behaviors aside, uncertainty also partially mediated associations between perceived susceptibility, perceived effectiveness, and perceived barriers influencing general response behaviors and sanitization practices, respectively. CONCLUSION: Findings provide evidence-based information to government and policymakers for designing effective health communication messages and intervention strategies by targeting the key constructs of the health belief model and reducing perceived uncertainty about COVID-19. They support public health-related response behaviors to prevent COVID-19 spread among the population.


Asunto(s)
COVID-19 , China/epidemiología , Control de Enfermedades Transmisibles , Estudios Transversales , Brotes de Enfermedades , Humanos , SARS-CoV-2 , Encuestas y Cuestionarios , Incertidumbre
14.
Gerontology ; 67(2): 243-254, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-33454703

RESUMEN

OBJECTIVES: To investigate whether caregiver neuroticism affects the level of elder abuse and whether changes of caregiver perceived burden alter this relationship. METHODS: Using 2-year longitudinal data, a consecutive sample of 800 Chinese family caregivers and their care recipients with dementia were recruited from the geriatric and neurological departments of 3 grade-A hospitals in the People's Republic of China. All the participatory dyads were assessed between September 2015 and February 2016 and followed up for 2 years. RESULTS: Significant increase in the prevalence was found for physical abuse, psychological abuse, and caregiver neglect. Caregiver neuroticism was associated with an increased level of physical and psychological abuse over the 2-year observation period; however, change in the level of caregiver perceived burden altered this association. Specifically, the absence and decrease of perceived care burden prevented an increase in the level of physical and psychological abuse among caregivers high in neuroticism. Although caregiver neuroticism was also associated with an increased level of caregiver neglect, caregiver perceived burden did not appear to have an impact on this relationship. DISCUSSION: This study provided evidence that caregiver neuroticism was associated with an increased level of physical and psychological abuse, while changes in the level of caregiver perceived burden may alter this trajectory. These findings suggest the importance of implementing caregiver-centered intervention and prevention programs for elder abuse by specifically targeting caregivers' behaviors related to their neurotic personality trait and cognitive appraisal of caregiving stressors associated with such personality traits.


Asunto(s)
Cuidadores , Abuso de Ancianos , Anciano , China/epidemiología , Humanos , Neuroticismo , Prevalencia
15.
Front Public Health ; 9: 809484, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-35141191

RESUMEN

OBJECTIVES: Internet Addiction (IA) is a growing issue predominate in adolescents and young adults. Although the effects of diverse stressors on IA have been highlighted, there is little consensus about the specific underpinnings of IA. The current study aims to investigate associations between uncertainty stress, life stress and IA among Chinese university medical students. METHODS: A cross-sectional survey employing multi-stage sampling was used. Data were collected from 6,061 students from 27 university medical programs across China. Associations between uncertainty stress, life stress, and IA were examined by means of multivariate logistic regression. RESULTS: The findings indicated that the overall IA prevalence was 12.6% (95% CI 11.7-13.5), life stress prevalence was 8.1% (95% CI 7.4-8.8), and uncertainty stress prevalence was 19.1% (95% CI 18.1-20.1). Multivariate logistic regression showed that uncertainty stress [adjusted OR 2.60 (95% CI 2.14-3.15), P < 0.001] and life stress [adjusted OR 1.71 (95% CI 1.32-2.23), P < 0.001] were positively associated with IA. Population Attributable Risk (PAR) of uncertainty stress associated with IA was 29%, and that of life stress was 15%. CONCLUSIONS: The contribution of uncertainty stress to IA is significantly higher than that of life stress. High uncertainty stress, being male and born in a region of higher economic status were associated with excessive Internet use and IA.


Asunto(s)
Conducta Adictiva , Estudiantes de Medicina , Adolescente , Conducta Adictiva/epidemiología , Estudios Transversales , Depresión/epidemiología , Femenino , Humanos , Trastorno de Adicción a Internet , Masculino , Estrés Psicológico/epidemiología , Encuestas y Cuestionarios , Incertidumbre , Adulto Joven
16.
BMC Ophthalmol ; 20(1): 355, 2020 Aug 31.
Artículo en Inglés | MEDLINE | ID: mdl-32867704

RESUMEN

BACKGROUND: Herpes simplex virus type 1 (HSV-1) keratitis is a major cause of corneal blindness in the world, and an in-depth understanding of its pathogenesis may help improve existing diagnosis and treatment. The purpose of this study is to compare and analysis the total tear protein profile of HSV-1 epithelial keratitis patients, and to quantify the potential candidate biomarkers of HSV-1 epithelial keratitis. METHODS: We investigated the proteome in tear fluid from three HSV-1 epithelial keratitis patients and three healthy control subjects using nano-scale liquid chromatography-tandem mass spectrometry (nLC-MS/MS) analysis. Functional annotation of differentially expressed proteins was done with the Gene Ontology (GO) analysis. ELISA was done to quantify the potential candidate biomarkers in 26 clinical cases. RESULTS: Tear fluid from three HSV-1 epithelial keratitis patients and three healthy control subjects contained a total of 1275 proteins and 326 proteins were unique to tear fluid of HSV-1 epithelial keratitis patients. Bioinformatics analysis revealed that tear proteins from HSV-1 epithelial keratitis patients may be involved in metabolic processes, antigen presentation, inflammatory response, and in the TNF-mediated and T cell receptor pathways. Furthermore, IL1A, IL12B, DEFB4A, and CAMP, which are associated with the inflammatory response and inhibition of viral infection, were significantly more abundant in the HSV-1 epithelial keratitis patients than in the healthy control subjects. CONCLUSIONS: This study reports the proteomic profile of tears in HSV-1 epithelial keratitis for the first time and identifies a number of unique differentially expressed proteins.


Asunto(s)
Herpesvirus Humano 1 , Queratitis Herpética , ADN Viral , Proteínas del Ojo , Herpesvirus Humano 1/genética , Humanos , Queratitis Herpética/diagnóstico , Proteómica , Espectrometría de Masas en Tándem
17.
Nicotine Tob Res ; 22(12): 2188-2195, 2020 12 12.
Artículo en Inglés | MEDLINE | ID: mdl-32516391

RESUMEN

INTRODUCTION: There is growing attention to social mobility's impact on tobacco use, but few studies have differentiated the two conceptually distinct mechanisms through which changes in social class can affect tobacco smoking: the class status effect and the mobility effect. AIMS AND METHODS: I applied Diagonal Reference Modeling to smoking and heavy smoking among respondents of the 1991 China Health and Nutrition Survey who were revisited two decades later in 2011 (n = 3841, 49% male, baseline mean age was 38 years). I divided the sample into six social classes (non-employment, self-employed, owners, workers, farmers, and retirees) and measured social mobility by changes in income and occupational prestige. RESULTS: About 61.7% of men were smokers and those from the classes of workers, owners, and self-employees consumed more cigarettes compared to the unemployed, but women smokers (3.7%) tend to be from the lower classes (unemployed and farmers). Controlling for social class, each 1000 Yuan increase in annual income led to smoking 0.03 more cigarettes (p < .05) and 1% increase (p < .05) in the likelihood of heavy smoking among men, but the income effect is null for women. Upwardly mobile men (a 10-points surge in occupational prestige) smoked like their destination class (weight = 78%), whereas men with downward mobility were more similar to peers in the original class (weight = 60%). CONCLUSIONS: Contrary to the social gradient in smoking in other industrial countries, higher class status and upward mobility are each associated with more smoking among Chinese men, but not among women. IMPLICATIONS: Tobacco control policies should prioritize male smoking at workplaces and the instrumental purposes of using tobacco as gifts and social lubricant. Taxation may counter the surge in smoking brought by individuals' income increase after upward mobility. Caution should be paid to women joining the similar social gradient in smoking as they gain foothold in the labor market.


Asunto(s)
Etnicidad/estadística & datos numéricos , Clase Social , Movilidad Social/estadística & datos numéricos , Fumar Tabaco/epidemiología , Adolescente , Adulto , Anciano , China/epidemiología , Etnicidad/psicología , Femenino , Humanos , Renta , Masculino , Persona de Mediana Edad , Fumar Tabaco/psicología , Adulto Joven
18.
Traffic Inj Prev ; 21(6): 375-381, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-32496809

RESUMEN

Objective: The purpose of this study was to investigate the prevalence and behavioral and psychosocial correlates of road traffic injuries (RTIs) among Chinese university students.Methods: A cross-sectional survey was conducted among fifty universities in China, using a multi-stage sampling methodology. The participants were asked to report their RTIs in the past year. The chi-square test and binary logistic regression analysis were utilized to identify factors associated with RTIs, including specific types of RTIs.Results: Among the 11,770 participants, a total of 1,482 university students reported at least one RTI yielding an overall weighted injury prevalence of 12.96% over the past year. Estimated weighted prevalence by type was 6.10%, 5.94%, 5.12%, and 5.35% for automobile (car, truck, or bus), bicycle, motorcycle, and pedestrian injuries, respectively. Logistic regression analysis found that students who studied at low-level universities, smoked cigarettes, drank alcohol, slept less than 7 hours, went to bed after 12:00 am, or students with psychological distress were more likely to experience overall and four types of RTIs. Students who studied in the eastern universities had a higher likelihood of automobile injury, motorcycle injury and pedestrian injury than those who studied in western universities.Conclusions: Several critical factors associated with RTIs were identified. These findings have implications for the design and implementation of RTI prevention and interventions programs targeted at university students.


Asunto(s)
Accidentes de Tránsito/estadística & datos numéricos , Estudiantes/psicología , Heridas y Lesiones/epidemiología , China/epidemiología , Estudios Transversales , Femenino , Humanos , Masculino , Prevalencia , Factores de Riesgo , Estudiantes/estadística & datos numéricos , Universidades , Adulto Joven
19.
J Health Soc Behav ; 61(1): 79-95, 2020 03.
Artículo en Inglés | MEDLINE | ID: mdl-32054337

RESUMEN

A dominant discourse in the social sciences theorizes that religious diversity puts individuals' health at risk via interreligious hostility. However, this discourse overlooks the different subtypes of religious diversity and the moderation of political institutions. To better understand the issue of diversity and health, in this study, we distinguish between two subtypes of religious diversity-polarization and fractionalization-and argue that their impacts on health are heterogeneous. Using a sample of 67,399 individuals from 51 societies drawn from the 2010-2014 wave of the World Values Survey, our multilevel analyses show that religious polarization is negatively associated with individual health, whereas the health effects of religious fractionalization are positive. Moreover, the associations between religious polarization/fractionalization and individual health are found to depend on the democratic level of the state. In more democratic countries, the negative effects of polarization on health are mitigated, and the positive effects of fractionalization are stronger.


Asunto(s)
Diversidad Cultural , Autoevaluación Diagnóstica , Religión , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Femenino , Estado de Salud , Humanos , Masculino , Persona de Mediana Edad , Factores Socioeconómicos , Encuestas y Cuestionarios , Adulto Joven
20.
Health Qual Life Outcomes ; 17(1): 168, 2019 Nov 08.
Artículo en Inglés | MEDLINE | ID: mdl-31703707

RESUMEN

BACKGROUND: With the disintegration of the extended family in recent years, the empty-nest phenomenon is increasingly common in China and the health of empty nesters is attracting more attention. Lifestyles, accounting for 53% in determining death, play a vital role in improving the health of individuals. However, it was rarely studied in promoting the health of empty nesters. In this study, we proposed a "SMG" model in empty nesters, including the self-management, mutual management, and group management, to implement health-promoting lifestyles interventions among empty nesters to provide an effective means to improve their lifestyles and health. METHODS: We conducted a prospective intervention on 350 empty nesters in three communities located in Taiyuan, China. One hundred sixty-seven empty nesters were randomly assigned to the intervention group with SMG-based health-promoting lifestyles interventions used for 7-months, and 183 were randomly assigned to the control group with no measures imposed. The Health-Promoting Lifestyle Profile (HPLP-C) was used to rate the lifestyles of empty nesters. Generalized estimation model was used to analyze the differences between the intervention and control groups over time, adjusted for education and employment. RESULTS: After 7 months of health-promoting lifestyles intervention, HPLP-C score and each dimension score in the intervention group all increase from baseline. There were significant differences after intervention associated with time and group interaction effects in aspects of HPLP-C (mean score = 8.838, 95%CI:6.369-11.306), self-realization (mean score = 1.443, 95%CI:0.352-2.534), Health responsibility (mean score = 1.492, 95%CI:0.477-2.508), physical activity (mean score = 1.031, 95%CI:0.572-1.491), nutrition (mean = 0.827, 95%CI:0.177-1.476), interpersonal relations (mean = 2.917, 95%CI:2.365-3.469) and stress management (mean score = 0.729, 95%CI:0.131-1.327). And education is contributing to the effect of the health-promoting lifestyle intervention (Estimate:8.833, p < 0.001). CONCLUSIONS: SMG-based health-promoting lifestyles intervention in empty nesters effectively improved the lifestyles of empty nesters, and the outcome was affected by education. Lifestyle change requires ongoing intervention, and community service centres must be involved in implementing the "SMG" model to provide ongoing support and improve the effect of interventions among empty nesters. TRIAL REGISTRATION: Chinese Clinical Trial ChiCTR1800015884. Registration date: 26-04-2018. Retrospectively registered.


Asunto(s)
Promoción de la Salud/métodos , Estilo de Vida Saludable , Anciano , Anciano de 80 o más Años , China , Composición Familiar , Femenino , Humanos , Relaciones Interpersonales , Masculino , Persona de Mediana Edad , Estudios Prospectivos , Calidad de Vida
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