Spectrum mapping technology based creation of a color-contrast reading environment to reach comfort and clarity.

Reading with a bit of yellowish or greenish paper, as compared to white paper, is thought to be more comfortable and friendly, and can help decrease eye fatigue to some degree. In this work, we try to map the light of different colors on a given paper within a region of interest to alter the colors presented by the paper and consequently influence the reading experience. We conducted an ergonomic experiment to study the comfort and clarity under consistent illuminance levels. We adopted 6 color series(red, yellow, green, cyan, blue, and magenta), 5 chroma levels(0, 10, 20, 30, 40), and 4 types of paper with the same hue(yellow) but different lightness(the white, light yellow, yellow, and dark yellow), and conducted pairwise selection experiments within each light color series. Results show that white and low chroma (≈10) color characteristics contribute to comfort, while higher chroma blue(30∼40) color benefits clarity. Referring to white, low chroma greenish and yellowish color characteristics are preferred in terms of comfort and clarity. This work proposes the spectrum mapping technology to endow the paper with new color effects and verifies that although spectrum compositions might differ, people's preferences and comfort perception are consistent with the same object color.

Ni-Substituted Sr2FeMoO6-δ as an Electrode Material for Symmetrical and Reversible Solid-Oxide Cells.

This work develops a novel perovskite Sr2FeNi0.35Mo0.65O6-δ (SFN0.35M) simultaneously using as a fuel electrode and oxygen electrode in a reversible solid oxide cell (RSOC). SFN0.35M shows outstanding electrocatalytic activity for hydrogen oxidation, hydrogen evolution, oxygen reduction, and oxygen evolution. In situ exsolution and dissolution of Fe-Ni alloy nanoparticles in SFN0.35M is revealed. In a reducing atmosphere, SFN0.35M shows in situ exsolution of Fe-Ni alloy nanoparticles, and then the Fe-Ni alloy is reoxidized into SFN0.35M while converting into an oxidizing atmosphere. The polarization resistances of SFN0.35M electrode are 0.043 Ω cm2 in 20% O2-N2 and 0.064 Ω cm2 in H2 at 850 °C. Moreover, symmetric fuel cells using the SFN0.35M electrode achieves a maximum power density of 0.501 W cm-2 at 850 °C in H2 fuel, while the symmetric electrolysis cell has an electrolysis current density of 0.794 A cm-2 at 1.29 V in 90% H2O-10% H2 at 850 °C. It is the first time we demonstrate that the cell voltage of symmetrical cell at 0.5 A cm-2 in the fuel cell mode and -0.5 A cm-2 in the electrolysis cell mode can be fully recovered in 10 electrode alternating cycles and therefore demonstrate the possibility that SFN0.35M can be used in a fully symmetric RSOC stack with electrode alternating functions.

Buoyancy-Driven Dissolution Instability in a Horizontal Hele-Shaw Cell.

The dissolution of minerals within rock fractures is fundamental to many geological processes. Previous research on fracture dissolution has highlighted the significant role of buoyancy-driven convection leading to dissolution instability. Yet, the pore-scale mechanisms underlying this instability are poorly understood primarily due to the challenges in experimentally determining flow velocity and concentration fields. Here, we integrate pore-scale simulations with theoretical analysis to delve into the dissolution instability prompted by buoyancy-driven convection in a radial horizontal geometry. Initially, we develop a pore-scale modeling approach incorporating gravitational effects, subsequently validating it through experiments. We then employ pore-scale numerical simulations to elucidate the 3D intricacies of flow-dissolution dynamics. Our findings reveal that a simple criterion can delineate the condition for the onset of buoyancy-driven dissolution instability. If the characteristic length falls below a critical threshold, dissolution remains stable. Conversely, exceeding this threshold leads to two distinct regimes: the unstable regime of the confined domain affected by the initial aperture and the unstable regime of the semi-infinite domain independent of the initial aperture where the instability is no longer influenced by the lower boundary. We demonstrate that the pore-scale mechanism for this instability is due to the concentration boundary layer attaining a gravitationally unstable critical thickness. Through theoretical analysis of this layer and the time scales of diffusion and advection, we establish a theoretical model to predict where the dissolution instability occurs. This model aligns closely with our numerical simulations and experimental data across diverse conditions. Our work improves the understanding of buoyancy-driven dissolution instability in radial horizontal geometry. It is also of practical significance in understanding cavity formation in karst hydrology and preventing leaks in geological CO2 storage.

Integrated assessment of the pollution and risk of heavy metals in soils near chemical industry parks along the middle Yangtze River.

Industrialization in riparian areas of critical rivers has caused significant environmental and health impacts. Taking eight industrial parks along the middle Yangtze River as examples, this study proposes a multiple-criteria approach to investigate soil heavy metal pollution and associated ecological and health risks posed by industrial activities. Aiming at seven heavy metals, the results show that nickel (Ni), cadmium (Cd), and copper (Cu) exhibited the most significant accumulation above background levels. The comprehensive findings from Pearson correlation analysis, cluster analysis, principal component analysis, and industrial investigation uncover the primary sources of Cd, arsenic (As), mercury (Hg), and lead (Pb) to be chemical processing, while Ni and chromium (Cr) are predominantly derived from mechanical and electrical equipment manufacturing. In contrast, Cu exhibits a broad range of origins across various industrial processes. Soil heavy metals can cause serious ecological and carcinogenic health risks, of which Cd and Hg contribute to >70 % of the total ecological risk, and As contributes over 80 % of the total health risk. This study highlights the importance of employing multiple mathematical and statistical models in determining and evaluating environmental hazards, and may aid in planning the environmental remediation engineering and optimizing the industry standards.

3D pore-scale characterization of colloid aggregation and retention by confocal microscopy: Effects of fluid structure and ionic strength.

Understanding the mechanisms of colloid transport and retention as well as the spatial distribution of colloids in porous media is an important topic for contamination transport and remediation in subsurface environments. Utilizing advanced three-dimensional visualization experiments, we effectively capture the intricate distribution characteristics of colloids in the 3D pore space and quantify the size of colloid clusters that aggregate at fluid-fluid interfaces and solid surfaces during two-phase flow. Our experimental results reveal the influence of pore-scale events, such as Haines jumps and pinch-off, on colloid retention. Our results also indicate that large drainage rates can facilitate colloid retention on solid surfaces, especially under the condition of high ionic strength. This can be attributed to the migration of colloids from the fluid-fluid interface to the solid surface, propelled by transients in the local fluid structure. The findings reveal a synergistic effect of the ionic strength and hydrodynamic conditions on colloid transport and retention during two-phase flow and provide important insights for predicting the fate and transport of contaminants in soil and groundwater environments involving multiple fluid phases.

Pore-scale investigation of surfactant-enhanced DNAPL mobilization and solubilization.

Surfactant-enhanced aquifer remediation has been proved successful to remove dense non-aqueous phase liquids (DNAPLs) from contaminated sites. However, the underlying mechanisms of the DNAPL mobilization and solubilization at the pore scale remains to be addressed for efficient application to the field remediation system. In this work, the emerging microfluidic and imaging technologies are applied to investigate the dynamics of DNAPL remediation. Visualized experiments of the evolution of DNAPL remediation are performed to study the role of surfactant type, concentration and injection rate. The DNAPL remediation is dominated by mobilization followed by solubilization for most surfactants. Mobilization occurs as soon as surfactants and DNAPL are in contact until forming a new stable phase structure, and the solubilization continues until the end of injection. We observe the breakup behavior of long droplets and ganglia during the mobilization, which is attributed to the surfactant-reduced interfacial tension and thus expedites DNAPL mobilization and redistribution. During the solubilization, the formation of micelles incorporating DNAPL fractions increases the DNAPL concentration gradient and thus enhances the mass transfer, but the rate-limited diffusion of micelles reduces the mass transfer rate coefficient. Increasing the surfactant content and decreasing the injection rate can promote mobilization and solubilization. The DNAPL mobilization ability of the surfactants SDS and SDBS is stronger than SAOS and Tween 80 regardless of the injection rates. Tween 80 may be considered an ideal surfactant of only solubilization but not mobilization is desired. This work elucidates the pore-scale mechanisms during surfactant-enhanced DNAPL remediation, which are beneficial for upscaling studies, predictive modeling, and operation optimization of DNAPL remediation in the field.

The impact of resilience on the mental health of military personnel during the COVID-19 pandemic: coping styles and regulatory focus.

Military personnel encountered multiple stressful events during the COVID-19 lockdown. Reducing non-combat attrition due to mental disorders is crucial for military morale and combat effectiveness. Grounded in stress theory and regulatory focus theory, this study investigates the influence of resilience on military personnel's mental health; coping style and regulatory focus are considered potential mediators and moderators, respectively. We conducted a routine psychological assessment on 1,110 military personnel in China. The results indicate that: (1) resilience has a negative impact on the psychological symptoms of military groups; (2) mature and mixed coping styles in military personnel mediate the association between resilience and psychological symptoms; and (3) regulatory focus predominance has a negative moderating effect on mature coping styles' effects on psychological symptoms. Furthermore, this study supports previous findings that resilience and mental health are interrelated; it demonstrates that military personnel can effectively reduce negative psychological symptoms by improving their resilience level and adopting mature coping styles under stressful situations. The current study presents interventional insights regarding coping styles and mental health from a self-regulatory perspective during the COVID-19 pandemic.

The military occupational stress response scale: Development, reliability, and validity.

Soldiers in the military are exposed to numerous stressors, including some that are of an extreme nature. The main objective of this military psychology research study was to evaluate soldiers' occupational stress. Even though several tools have been developed to measure stress in this population, to date, none have focused on occupational stress. Hence, we developed the Military Occupational Stress Response Scale (MOSRS) to provide a tool to objectively measure soldiers' occupational stress responses. An initial pool of 27 items was assembled from the literature, existing instruments, and interviews with soldiers. Of those 27, 17 were included in the MOSRS. The scale was subsequently completed by soldiers from one military region, and exploratory factor analysis (EFA) and confirmatory factor analysis were conducted using Mplus8.3 and IBM SPSS 28.0 software, respectively. A total of 847 officers and soldiers were selected for scale testing, and 670 subjects were retained after data cleaning and screening according to the set criteria. After performing the Kaiser-Meyer-Olkin (KMO) and Bartlett's test, principal components analysis (PCA) was appropriate. The PCA yielded a three-factor model (physiological, psychological, and behavioral responses) with the items and factors strongly correlated. The confirmatory factor analysis revealed loads ranging from between 0.499 and 0.878 for each item. The Cronbach's α coefficient of the MOSRS was between 0.710 and 0.900, and the Omega reliability was between 0.714 and 0.898, which were all higher than the critical standard value of 0.7, indicating that the scale has good reliability. Analysis of the discrimination validity of each dimension revealed that the scale has good discrimination validity. The MOSRS demonstrated sound psychometric characteristics with acceptable reliability and validity, suggesting that it could be used to assess occupational stress in military personnel.

Molecular Origin of Wetting Characteristics on Mineral Surfaces.

Accurate determination of the wetting characteristics on mineral surfaces is critical for many natural processes and industrial applications where multiphase flow in porous media is involved. The wetting behaviors on mineral surfaces are controlled by water-mineral interactions, giving rise to various wetting characteristics, including contact line advancement, formation of precursor films, etc. However, a fundamental understanding of wetting characteristics on different mineral surfaces is still lacking at the molecular level. Here, utilizing a comprehensive set of molecular dynamics simulations, we investigate the wetting characteristics of water on various mineral surfaces and obtain the corresponding water-mineral interaction properties (including the areal density of water-mineral interaction energy and the work of adhesion of the water-mineral interface), mineral wettability, and structural and diffusion properties of water molecules near the surface. We show that the diffusion properties of water molecules on mineral surfaces play an important role in wetting characteristics. We find that the contact line tends to advance forward in the jumping mode or the rolling mode during the wetting process, which depends on the diffusion capacity of the water molecules on mineral surfaces. The corresponding evolution of the solid-liquid friction coefficient during dynamic spreading is also analyzed. We further demonstrate the strong impact of isomorphic substitution and charge-balancing counterions on wetting characteristics on the surfaces of clay minerals. It is shown that the introduction of charge-balancing counterions can shift the mineral surface from strongly hydrophilic to strongly hydrophobic and lead to completely different wetting characteristics. Our results provide a clearer picture of the molecular underpinnings in mineral wetting phenomena and deepen the understanding of the control of water-mineral interactions on the wetting properties.

Three-Dimensional Visualization Reveals Pore-Scale Mechanisms of Colloid Transport and Retention in Two-Phase Flow.

Colloids are ubiquitous in the natural environment, playing an important role in facilitating the transport of absorbed contaminants. However, due to the complexities arising from two-phase flow and difficulties in three-dimensional observations, the detailed mechanisms of colloid transport and retention under two-phase flow are still not well understood. In this work, we visualize the colloid transport and retention during immiscible two-phase flow based on confocal microscopy. We find that the colloid transport and retention behaviors depend strongly on the flow rate and pore/grain size. At low levels of saturation (high flow rate) with the wetting liquid mainly present as pendular rings, the colloids can aggregate at the liquid filaments in small-grain packings and are uniformly distributed in large-grain packings. Through theoretical analysis of the pendular ring geometry, we elucidate the mechanism responsible for the strong dependence of colloid clogging behavior on solid grain size. Our results further demonstrate that even at dilute concentrations, colloids can alter the flow paths and the wetting fluid topology, suggesting a strong two-way coupling dynamics between immiscible two-phase flow and colloid transport and calling for improved predictive models to incorporate the overlooked clogging behavior.

A pore-scale investigation of microplastics migration and deposition during unsaturated flow in porous media.

Microplastics are ubiquitous in the natural environment and have the potential to endanger the natural environment, ecology and even human health. A series of microfluidic experiments by using soft lithography technology were carried out to investigate the effect of flow rate, particle volume fraction, particle size and pore/throat ratio on microplastics migration and deposition at the pore scale. We discovered a range of deposition patterns of the spherical microplastics from no particle deposition, to discontinuous particle layer, and to continuous particle layers in the retained liquid in the pores, depending on the particle size and volume fraction. Several metrics, including air saturation, probability of particle detainment, expansion ratio and thickness of residual liquid, were quantified to examine the role of various parameters on particle migration and retention of microplastics. At low flow rate (Q = 0.05 µL/min), microplastics migration and deposition were sensitive to changes in particle volume fraction, particle size and pore/throat ratio. In contrast, at high flow rates (Q > 5 µL/min), the migration and retention of particles were mainly controlled by strongly channelized air invasion pattern, while the particle volume fraction, particle size and pore/throat size ratio have only secondary influence. At intermediate range of flow rates, microplastics migration and deposition were dramatically impacted by flow rate, particle volume fraction, particle size and pore/throat ratio. This work improves the understanding of the mechanisms of particle migration and retention in porous media and can provide a reference for more accurate assessment of the exposure levels and times of microplastics in soil and groundwater systems.

Relationship amongst Noise Sensitivity, Burnout and Psychological Resilience in Community Workers.

Background: The mental health status of community workers shows the characteristics of low job satisfaction, low self-efficacy and psychological resilience, and a high sense of burnout. This research aims to explore the relationship between noise sensitivity, burnout, and psychological resilience in community workers. Methods and Material: Convenience sampling was adopted to select 169 community workers from five communities as research objects for an anonymous questionnaire survey. A general questionnaire was used to collect the general information of the respondents. Noise sensitivity, burnout and psychological resilience scales were adopted to analyse the correlation amongst noise sensitivity, burnout and psychological resilience in community workers. Univariate and multivariate logistics regression analyses were used to analyse the influencing factors of job burnout and psychological resilience in community workers. Results: A total of 169 questionnaires were distributed, and after excluding 6 unqualified questionnaires, 163 valid questionnaires (96.45%) were collected. The scores on the noise sensitivity, burnout and psychological resilience scales were 63.80 ± 9.69, 78.57 ± 10.12 and 54.18 ± 8.77 points, respectively. The results of the correlation analysis showed that in community workers, the noise sensitivity score was negatively correlated with the psychological resilience score (P < 0.001) and positively correlated with the burnout score (P < 0.001). The burnout and psychological resilience scores of community workers showed statistical differences with different ages, working years and disposable monthly family income (P < 0.001). Multiple linear regression results revealed that noise sensitivity, age, working years and disposable monthly family income had an effect on burnout and psychological resilience scores (P < 0.001). Conclusion: In community workers, noise sensitivity is positively correlated with burnout and negatively correlated with psychological resilience. This study provides a certain research basis for conducting relevant psychological research and interventions.

Molecular signatures of soil-derived dissolved organic matter constrained by mineral weathering.

Dissolved organic matter (DOM) in soils drives biogeochemical cycling and soil functions in different directions depending on its molecular signature. Notably, there is a distinct paucity of information concerning how the molecular signatures of soil DOM vary with different degrees of weathering across wide geographic scales. Herein, we resolved the DOM molecular signatures from 22 diverse Chinese reference soils and linked them with soil organic matter and weathering-related mineralogical properties. The mixed-effects models revealed that the yields of DOM were determined by soil organic carbon content, whereas the molecular signature of DOM was primarily constrained by the weathering-related dimension. The soil weathering index showed a positive effect on the lability and a negative effect on the aromaticity of DOM. Specifically, DOM in highly weathered acidic soils featured more amino sugars, carbohydrates, and aliphatics, as well as less O-rich polyphenols and condensed aromatics, thereby conferring a higher DOM biolability and lower DOM aromaticity. This study highlights the dominance of the weathering-related dimension in constraining the molecular signatures and potential functions of DOM in soils across a wide geographic scale.

Pore-Scale Mechanisms of Solid Phase Emergence During DNAPL Remediation by Chemical Oxidation.

In situ chemical oxidation (ISCO) has proven successful in the remediation of aquifers contaminated with dense nonaqueous phase liquids (DNAPLs). However, the treatment efficiency can often be hampered by the formation of solids or gas, reducing the contact between remediation agents and residual DNAPLs. To further improve the efficiency of ISCO, fundamental knowledge is needed about the complex multiphase flow and reactive transport processes as new solid and fluid phases emerge at the microscale. Here, via microfluidic experiments, we study the pore-scale dynamics of trichloroethylene degradation by permanganate. We visualize how the remediation evolves under the influence of solid phase emergence and explore the roles of injection rate, oxidant concentration, and stabilization supplement. Combining image processing, pressure analysis, and stoichiometry calculations, we provide comprehensive descriptions of the oxidant concentration-dependent growth patterns of the solid phase and their impact on the remediation efficiency. We further corroborate the stabilization mechanism provided by phosphate supplement, which is effective in inhibiting solid phase generation and thus highly beneficial for the oxidation remediation. This work elucidates the pore-scale mechanisms during remediation of chlorinated solvents with a particular context in the solid phase production and the associated effects, which is of general significance to understanding various processes in natural and engineered systems involving solid phase emergence or aggregation phenomena, such as groundwater and soil remediation.

Mastoparan M extracted from Vespa magnifica alleviates neuronal death in global cerebral ischemia-reperfusion rat model.

Objectives: Global cerebral ischemia (GCI), a consequence of cardiac arrest (CA), can significantly damage the neurons located in the vulnerable hippocampus CA1 areas. Clinically, neurological injury after CA contributes to death in most patients. Mastoparan-M extracted from Vespa magnifica (Smith) can be used to treat major neurological disorders. Hence, this study aimed to assess the effects of Mastoparan-M on GCI. Materials and Methods: To evaluate the neurotoxicity and neuroprotective effect of Mastoparan-M, the CCK8 and Annexin V-FITC/PI apoptosis assays were first performed in hippocampal HT22 neuronal cells in vitro. Then, Pulsinelli's 4-vascular occlusion model was constructed in rats. After treatment with Mastoparan-M (0.05, 0.1, and 0.2 mg/kg, IP) for 3 or 7 days, behavioral tests, H&E staining or Nissl staining, immunohistochemistry, and ELISA were employed to investigate neuroprotective effects of Mastoparan-M on GCI in rats. Results: In vitro, the growth of HT22 neuronal cells was restrained at concentrations of 30-300 µg/ml (at 24 hr, IC50=105.2 µg/ml; at 48 hr, IC50=46.81 µg/ml), and Mastoparan-M treatment (0.1,1 and 5 µg/ml) restrained apoptosis. In vivo, Mastoparan-M improved neurocognitive function and neuronal loss in the hippocampal CA1 area of rats. In addition, these effects were associated with the prevention of neuroinflammation, oxidative stress, and apoptosis. Conclusion: Mastoparan-M acts as a neuroprotective agent to alleviate neuronal death in rats.

Flood inundation evolution of barrier lake and evaluation of regional ecological spatiotemporal response-a case study of Sichuan-Tibet region.

The Himalayan volcanic earthquake zone has significantly impacted China's Sichuan-Tibet region. Many barriers have formed as a result of the earthquake and secondary disasters, such as landslides, which have blocked the river. The breach of the barrier lake seriously threatens the lives and property safety of downstream personnel. There has been little research on the surrounding ecology for the later treatment of the barrier lake. This paper aims to scientifically predict the risk of dam break in a barrier lake as well as to explore its impact on the ecological environment and put forward controllable measures. Based on four major barrier lake events in the Sichuan-Tibet area, Diexihaizi, Tangjiashan barrier lake, and so on, we extract water bodies from remote sensing images and use the HEC-RAS (Hydrologic Engineering Center of River Analysis System) model to investigate whether there is a dam break risk and the route of the dam break is predictable. Simultaneously, from 1990 to 2020, the smallest administrative region is located. The InVEST (Integrated Valuation of Ecosystem Services and Tradeoffs) model is utilized to evaluate and analyze its habitat and create an evaluation based on flood inundation data. The results suggest that a stable barrier lake (such as Diexihaizi) has a sound effect on the habitat quality index following engineering treatment. The development of the barrier lake has altered the types of neighboring lands used and the natural patterns of the region's landscape. The habitat quality index will marginally deteriorate within a 1-km radius of the barrier lake. However, the quality of habitats in the area ranging within 3 km and 5 km has improved. It is necessary to discharge and strengthen the barrier lake artificially. Human-controlled regions, according to studies, will recover higher habitat quality index values than other locations. Whether the barrier lake has a positive impact on the surrounding area, on the other hand, is primarily dependent on the original ecology. The development of barrier lakes is damaging and unprofitable in Tibet, where the actual ecology is better in the short term. Still, in Sichuan Province, where the habitat quality is relatively low, the appearance of dammed lakes has played a role in correcting the ecology.

Roles of energy dissipation and asymmetric wettability in spontaneous imbibition dynamics in a nanochannel.

HYPOTHESIS: The imbibition dynamics is controlled by energy dissipation mechanisms and influenced by asymmetric wettability in a nanochannel. We hypothesize that the imbibition dynamics can be described by a combined model of the Lucas-Washburn equation and the Cox-Voinov law considering velocity-dependent contact angles. METHODS: Molecular dynamics simulations are utilized to investigate the imbibition dynamics. A wide range of wetting conditions is achieved via adjusting the liquid-solid interaction parameters, and the spontaneous imbibition processes are quantified and compared. FINDINGS: The critical condition for the occurrence of spontaneous imbibition is analyzed from a surface energy perspective. The analyses of energy conversion and dissipation indicate that the viscous dissipation is dominant during spontaneous imbibition. The classical Lucas-Washburn equation is modified with the Cox-Voinov law considering the effect of the dynamic contact angle and an effective equilibrium contact angle. We show that the proposed theory well captures the imbibition dynamics embodied in the growth of imbibition length as well as the transient interface shape and velocity for both the symmetric and asymmetric wetting conditions. In nanochannels with asymmetric wettability, the imbibition length difference between the sidewalls and interface oscillations increases with wetting disparity. Our findings deepen the understanding of imbibition dynamics on the nanoscale, and provide a theoretical reference for relevant applications.

Morphological patterns and interface instability during withdrawal of liquid-particle mixtures.

HYPOTHESIS: The stability of fluid-fluid interface is key to control the displacement efficiency in multiphase flow. The existence of particles can alter the interfacial dynamics and induce various morphological patterns. Moreover, the particle aggregations are expected to have a significant impact on the interface stability and patterns. EXPERIMENTS: Monodisperse polyethylene particles of different sizes are uniformly mixed in silicone oil to form the granular mixtures, which are injected into a transparent radial Hele-Shaw cell through different strategies to obtain the homogeneous and inhomogeneous (with particle aggregations) initial states. Subsequently, a systematic study of morphology and interface stability during the withdrawal of granular mixtures is performed. FINDINGS: For homogeneous mixtures, we observe earlier onset of fingering, more fingers and lower gas saturation at breakthrough than for pure fluid with equivalent viscosity. This effect can be attributed to the particle-induced perturbations. For inhomogeneous mixtures, particle clusters and bands significantly enhance the interface instability. Furthermore, we find that particle deposition due to liquid film entrainment occurs above a critical local flow velocity, and we elucidate the responsible mechanism through force balance analysis and the thin film theory. This work could be of practical significance in geoenergy and industrial applications.

Film entrainment and microplastic particles retention during gas invasion in suspension-filled microchannels.

Understanding of microplastics transport mechanism is highly important for soil contamination and remediation. The transport behaviors of microplastics in soils are complex and influenced by various factors including soil and particle properties, hydrodynamic conditions, and biota activities. Via a microfluidic experiments we study liquid film entrainment and microplastics transport and retention during two-phase displacement in microchannels with one end connected to the air and the other connected to the liquid with suspended particles. We discover three transport patterns of microplastic particles, ranging from no deposition to particle entrapment and to particle layering within liquid films, depending on the suspension withdrawal rates and the particle volume fraction in the suspension. The general behavior of particle motion is effectively captured by the film thickness evolution which is shown to be dependent on a modified capillary number Ca0 taking into account the effects of flow velocity, particle volume fraction, and channel shape. We also provide a theoretical prediction of the critical capillary number Ca0* for particle entrapment, consistent with the experimental results. In addition, the probability of microplastics being dragged into the trailing liquid film near the gas invading front is found to be proportional to both particle volume fraction and the capillary number. This work elucidates the microplastics transport mechanism during unsaturated flow, and therefore is of theoretical and practical importance to understand the contaminant migration in many natural and engineered systems spanning from groundwater sources to water treatment facilities.

Neonatal exposure to environment-relevant levels of tributyltin leads to uterine dysplasia in rats.

Endocrine-disrupting chemicals (EDCs) are natural/synthetic compounds that mimic or inhibit the biological actions of endogenous hormones. Studies have revealed that environmental estrogen, such as bisphenol A (BPA), causes developmental defects in the uterus. Tributyltin (TBT) is a typical environmental androgen. In this study, we aimed to explore the effect and mechanism of TBT on uterine development. Neonatal female rats were exposed to TBT (10 and 100 ng/kg bw) from postnatal days 1 to 16. BPA (50 µg/kg bw) was used as a positive control. Neonatal exposure to environmental concentrations of TBT resulted in pathological changes in the uterus, including thickening of the uterine luminal epithelium, a low density of glands, endometrial inflammation and fibrosis. Further, TBT affected the Wnt signaling pathway, which might mediate developmental disorders of the endometrial epithelial cells and glands in the uterus. TBT exposure also activated the NF-κB signaling pathway, which triggered inflammation. Moreover, TBT exposure upregulated the TGF-ß/Smads signaling pathway, possibly leading to endometrial fibrosis. In summary, our results demonstrate that neonatal exposure to an environment-relevant level of TBT leads to uterine dysplasia and provide potential molecular mechanisms. Our study is helpful for clarifying the effects of environmental androgens on the female reproduction system.