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1.
J Adv Nurs ; 79(3): 865-884, 2023 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-35511714

RESUMEN

AIMS: To investigate and describe the current state of knowledge about Fundamental Care in terms of population, contexts, concepts and gaps. DESIGN: A scoping review. DATA SOURCES: CINAHL, Medline, PsycINFO and EMBASE databases were searched in April 2021 for eligible literature, published from January 2010, onwards. REVIEW METHODS: This scoping review was built around the recommendations of Peters et al. (2020 version). Two researchers conducted the literature search, and three researchers independently screened the titles and abstracts of the retrieved studies' data, using the eligibility criteria and the review questions as a guide. RESULTS: The search yielded 763 records, of which 107 were included. Results are presented under seven subheadings: (a) Countries and Continents, (b) Context, (c) Research Design, (d) Publishing/Journal, (e) Participants and Population, (f) Keywords and (g) Fundamental of Care Framework and Practice Process. All the retrieved articles describe the current state of knowledge about Fundamental Care in terms of population, contexts, concepts and gaps. CONCLUSION: This scoping review highlighted the elevated number of articles that have been published since the beginning of the work on Fundamental Care, 10 years ago. The included articles are related to different dimensions of research, practice and teaching and to the Fundamentals of Nursing Care, but also to nursing theory. Finally, most of the articles had a nursing focus. IMPACT: The results of this scoping review allow us to highlight the work from the past 10 years. This may be of interest to learn more about the research surrounding Fundamental Care. This scoping review allows us to better target the theoretical and empirical developments to focus on in the coming years.


Asunto(s)
Atención de Enfermería , Humanos , Aprendizaje , Teoría de Enfermería
2.
Chem Commun (Camb) ; 54(81): 11463-11466, 2018 Oct 09.
Artículo en Inglés | MEDLINE | ID: mdl-30255872

RESUMEN

A method for the carboallylation of electron-deficient alkenes with tetraorganosilicon reagents and allylic carbonates based on Pd/Cu catalysis has been developed. This method affords a wide range of structurally diverse carbon skeletons from readily available starting materials, and tolerates various functional groups.

3.
Phys Rev Lett ; 121(25): 257201, 2018 Dec 21.
Artículo en Inglés | MEDLINE | ID: mdl-30608774

RESUMEN

Using high-resolution spin-resolved photoemission spectroscopy, we observe a thermal spin depolarization to which all spin-polarized electrons contribute. Furthermore, we observe a distinct minority spin state near the Fermi level and a corresponding depolarization that seldom contributes to demagnetization. The origin of this depolarization has been identified as the many-body effect characteristic of half-metallic ferromagnets. Our investigation opens an experimental field of itinerant ferromagnetic physics focusing on phenomena with sub-meV energy scale.

4.
Bioorg Med Chem Lett ; 17(9): 2590-3, 2007 May 01.
Artículo en Inglés | MEDLINE | ID: mdl-17317168

RESUMEN

A novel lipid analog based on amino acids for liposome modification was developed. It consisted of three different kinds of amino acid derivatives and two fatty acids, and can react directly with the peptide synthesized first on resin by Fmoc solid-phase synthesis. In this study, lipid analog conjugated with HIV-TAT peptide (domain of human immunodeficiency virus TAT protein) was synthesized and successfully incorporated into liposome. The liposome containing the lipopeptide bearing HIV-TAT exhibited efficient cellular uptake.


Asunto(s)
Química Farmacéutica/métodos , Productos del Gen tat/química , Lípidos/química , Liposomas/química , Péptidos/química , Animales , Células COS , Chlorocebus aethiops , Cromatografía Líquida de Alta Presión , Diseño de Fármacos , Ácidos Grasos/química , Espectroscopía de Resonancia Magnética , Modelos Químicos , Conformación Molecular , Espectrometría de Masa por Láser de Matriz Asistida de Ionización Desorción
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