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PLoS One ; 17(2): e0263587, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-35113973

RESUMEN

AIM: To evaluate the association between the value of neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), monocyte to high-density lipoprotein ratio (MHR) and the development of retinal artery occlusion (RAO) and retinal vein occlusion (RVO). METHODS: This retrospective study assessed 41 RAO, 50 RVO and 50 control (age and gender matched senile cataract) participants. The NLR, PLR and MHR parameters of patients' peripheral blood were analyzed. A receiver operating characteristics (ROC) curve analysis and the best cutoff value were used to specify the predictive value of NLR, PLR and MHR in RAO and RVO. RESULTS: The NLR, PLR and MHR were significantly higher in RAO group compared to the control group (p<0.001, p<0.001 and p = 0.008; respectively). The NLR, PLR and MHR were also significantly higher in the RVO group compared to the control group (p<0.001, p = 0.001 and p = 0.012, respectively). The NLR and PLR were significantly higher in the RAO group compared to the RVO group (p<0.001 and p = 0.022, respectively). The optimal cut-off value of NLR to predict RAO was >2.99, with 90.2% sensitivity and 100% specificity. The PLR to predict RAO was > 145.52, with 75.6% sensitivity and 80.0% specificity. CONCLUSION: Higher NLR, PLR and MHR are related to the occurrence of RAO and RVO. NLR and PLR are more prominent in RAO compared to RVO.


Asunto(s)
Plaquetas/citología , Linfocitos/citología , Neutrófilos/citología , Oclusión de la Arteria Retiniana/sangre , Oclusión de la Arteria Retiniana/fisiopatología , Anciano , Biomarcadores , Femenino , Humanos , Inflamación , Recuento de Linfocitos , Masculino , Monocitos , Recuento de Plaquetas , Curva ROC , Oclusión de la Vena Retiniana , Estudios Retrospectivos , Sensibilidad y Especificidad , Resultado del Tratamiento
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