Stress influence on real-world driving identified by monitoring heart rate variability and morphologic variability of electrocardiogram signals: the case of intercity roads.

Objectives. This study examines which of the heart rate variability (HRV) and morphologic variability (MV) metrics may have the highest accuracy in different stress detection during real-world driving. Methods. The cross-sectional study was carried out among 93 intercity mini-bus male drivers aged 22-67 years. The Trillium 5000 Holter Recorder and GARMIN Virb Elite camera were used to determine heart rate and vehicle speed measurements along the path, respectively. We considered the HRV and MV metrics of electrocardiogram (ECG) signals including the mean RR interval (mRR), mean heart rate (mHR), normalized low-frequency spectrum (nLF), normalized high-frequency spectrum (nHF), normalized very low-frequency spectrum (nVLF), difference of normalized low-frequency spectrum and normalized high-frequency spectrum (dLFHF), and sympathovagal balance index (SVI). Results. The analysis showed that the HRV metrics mHR, mRR, nVLF, nLF, nHF, dLFHF and SVI are effective in mental stress detection while driving as compared to rest time. We obtained a high accuracy of stress detection for MV metrics as compared to the traditional HRV analysis, of approximately 92%. Conclusions. Our findings indicate that driver stress could be detected with an accuracy of 92% using MV metrics as an accurate physiological index of the driver's state.

Assessing occupational exposure of airborne PMs and TVOCs in the nail salons in Tehran city, Iran.

There are concerns about the health of nail salon technicians due to the inherently harmful agents such as volatile organic compounds (VOCs) and released particles in the salons. For this reason, this study was conducted to investigate the occupational exposure of nail salon technicians to VOCs and particulate matters (PMs) in the nail salons in Tehran, Iran. In this cross-sectional study, indoor air quality and measurement continually Total VOCs and PMs in the various size of PM1-PM10 using PhoCheck Tiger and particle counter device investigated, respectively. site observation, and an interview with the manager in 49 salons in Tehran. Data was analyzed using SPSS software (version 22). Mean concentrations of PM1 with 2.56 µÉ¡/m3 was the lowest amount and PM10 with 346.86µÉ¡/m3 had the highest concentration. Also, the mean concentration of TVOCs was equal 2.61 ppm. The results of the regression model showed that there is a statistically significant between the number of services with airborne PMs (PM2.5), (p-Value≤0.050). In salons only with nail activities, the concentration of PM4 was less than the others, although this correlation was statistically significant just for PM1 (p-Value = 0.010). By implementing effective local exhaust ventilation systems equipped with dust collectors and utilizing safe products, the emission of particles and chemical compounds within salons can be significantly reduced.

Exposure assessment to BTEX in the air of nail salons in Tehran city, Iran.

The nail salon industry has grown considerably, but there are serious concerns about the health risks associated with working in this field. Therefore, the purpose of this study was to investigate the exposure of nail technicians to BTEX. A cross-sectional study was conducted on 49 salons, and NIOSH Method 1501 was used to measure the concentration of BTEX in the breathing zone of technicians. The EPA method was used to assess health risks. Statistical analysis was conducted using SPSS software. The mean concentrations of toluene were (82.65 ± 198.84µg/m3)µg/m3, followed by benzene (10.58 ± 9.62µg/m3), p-xylenes (20.77 ± 37.79µg/m3), o-xylene (13.79 ± 25.70µg/m3), and ethylbenzene (29.35 ± 58.26µg/m3) , that lower than the permissible exposure limits suggested by NIOSH. Among the BTEX, toluene (82.65 ± 198.84µg/m3) has the most concentration in the nail salons. It was also discovered through multiple linear regression analysis that humidity had a significant effect on increasing the concentration of toluene (Beta = 0.50, P-value = 0.001) and ethylbenzene (Beta = 0.16, P = 0.049), while there was a considerable association between the number of services performed and benzene concentration (Beta = 0.34, P = 0.010). The average inhalation lifetime cancer risk for benzene (4.9 × 10 -5±4.5 × 10-5) was higher than the recommended value set by the US EPA. Although the concentrations of BTEX were lower than the maximum permissible limits, the results of the cancer risk assessment for benzene showed that working in nail salons with poor ventilation is hazardous. Therefore, exposure can be minimized by ensuring appropriate ventilation in the workplace and using safe products.

The effect of subacute co-exposure to carbon tetrachloride and diclofenac on the liver of male wistar rats.

Carbon tetrachloride (CCl4) is a potent liver toxin. Diclofenac (Dic), leading adverse effects on the liver, is used among the employees of the industries that use CCl4. The increased use of CCl4 and Dic in industrial workers has prompted us to investigate their synergistic effect on the liver using male Wistar rats as a model. Male Wistar rats were divided into seven groups (n = 6), and the exposure was by intraperitoneal injection for 14 days as follows. Group 1: Control, 2: Olive oil, 3: CCl4 (0.8 mL/kg/day (3 times per week)), 4: Normal saline, 5: Dic (1.5 mg/kg/day per day), 6: Olive oil with normal saline, 7: CCl4 (0.8 mL/kg/day (3 times per week)) and Dic (1.5 mg/kg/day daily). At the end of day 14, the heart blood was collected to measure the liver enzymes, alanine-aminotransferase (ALT), aspartate-aminotransferase (AST), blood alkaline phosphatase (ALP), albumin (ALB), direct bilirubin, and total bilirubin. A pathologist examined the liver tissue. Prism software was used to analyze data using ANOVA and Tukey statistical tests. ALT, AST, ALP, and Total Bilirubin enzymes were increased significantly in the co-administered CCl4 and Dic group, while the ALB levels decreased (p < 0.05). The histological findings reported liver necrosis, focal hemorrhage, adipose tissue change, and lymphocytic portal hepatitis. In conclusion, using Dic while exposed to CCl4 may exacerbate hepatotoxicity in rats. Therefore, it is suggested that more severe restrictions and safety regulations be placed on using CCl4 in the industry, and caution is advised to these industry workers to use Diclofenac.

The impact of emotional intelligence and personality traits on the occurrence of unsafe behaviors and needle stick injuries among the nurses.

This study was aimed to investigate the effect of emotional intelligence and some personality traits on safe behavior and needle stick injuries among the nurses. This cross-sectional study was performed on 200 nursing staff of a hospital in Iran. To collect data, individuals were asked to complete several questionnaires, including demographic questionnaire, domain-specific risk-taking questionnaire, Rosenberg self-confidence questionnaire, Buss-Perry aggression questionnaire, Goleman emotional intelligence questionnaire, and safe behavior questionnaire. Also, the number of needlestick injuries in the participants was extracted from their medical records. Data were analyzed using the SPSS software (version 22), and path analysis was performed using AMOS software. The prevalence of needle stick injuries in the subjects was estimated by 45.5 percent. The results showed that increasing risk-taking, increasing aggression, decreasing self-confidence, and decreasing emotional intelligence reduced safe behavior and increased the number of needle injuries (P < 0.001). In the present study, some personal traits affecting the occurrence of needlestick injuries were identified. It is recommended that people without these negative traits are applied in dangerous occupations with a high probability of needle stick injuries.

Investigating the relationship between occupational exposure to nanomaterials and symptoms of nanotechnology companies' employees.

PURPOSE: The increasing use of nanomaterials in academic and industrial environments has raised concerns about the potential effects of these materials on human and the environment. Researches have shown that occupational exposure to nanomaterials can affect employees' health. Many companies are active in the field of nanotechnology in Iran. Therefore, this study was designed and conducted to investigate the relationship between the symptoms of these companies' employees and exposure to nanomaterials. METHODS: The study was conducted among employees of 52 nanotechnology companies in Tehran. For this study, the employees of these companies were categorized in two groups: "exposed" and "non-exposed" to nanomaterials. Data collection tools included the NanoTool method form and a nonspecific symptom questionnaire designed and validated by a team of 19 experts in various fields. Finally, data were analyzed using SPSS.22 software. RESULTS: The results showed that the frequency of cutaneous (such as roughness, itching and redness), respiratory (such as cough, sneezing, and burning throat) and ocular (such as burning, itching and redness) symptoms were higher among the exposed workers to nanomaterials. Examination of the correlation between these symptoms in the two studied groups showed that symptoms with high frequency have a significant relationship with exposure to nanomaterials. CONCLUSIONS: Given the high prevalence of some symptoms among the employees of the studied companies and their association with exposure to nanomaterials, it seems necessary to take control measures to reduce the exposure of employees to nanomaterials and consequently reduce the Investigated symptoms.

Improving healthy work culture measures using participatory ergonomic interventions.

Objectives. The productivity outcomes from proper implementation of participatory ergonomic interventions in industrial developing countries (IDCs) are important to have management support. However, the role of awareness promotion in engaged groups of intervention has been overlooked. This article explains the health effects of some ergonomic interventions including nutrition awareness, training and workstation redesign on the labor productivity indices of an industry using participatory ergonomics. Methods. The study design was a semi-experimental study. After the field study, the proper model of participatory ergonomics was presented to implement the interventions. The International Labour Organization (ILO) checkpoint, quick exposure check (QEC) checklist and Nordic questionnaire were applied to assess ergonomic risk factors. Labor productivity was measured using some indicators of health and production. Statistical tests including paired-sample t tests were performed for data analysis using SPSS version 22.0. Results. The ergonomic interventions with a focus on awareness promotion resulted in positive outcomes (p < 0.05) including a decrease of blood pressure (equally 3.1%), improvement in optimum monthly performance of labors, better QEC number and also time saving of about 18.93% in doing tasks. Conclusion. Awareness promotion and productivity outcomes were found to be important in management commitment and support to persuade participatory ergonomic interventions.

Prevention measures and risk factors for COVID-19 in Iranian workplaces.

BACKGROUND: Exposure to the coronavirus (COVID-19) in industrial workplaces has caused concerns all over the world. Implementation of prevention measures is the best solution for protection of workers' health. OBJECTIVE: The present study investigated prevention measures and risk factors for the COVID-19 infection in Iranian small, medium, and large industries. METHODS: This study was conducted on 349 occupational health, safety, and environment professionals working in different industries. Data was collected using a checklist of prevention measures for COVID-19 and a questionnaire of risk factors for the infection. RESULTS: The results demonstrated that 32.60% of industries reported positive cases of COVID-19. The mean of prevention measures in all the dimensions, except use of personal protective equipment (PPE), was in favorable status. Among prevention measures against COVID-19, the dimensions of education, engineering controls, use of PPE, use of hand washing soap and disinfectant, and physical distance were not significantly different among small, medium, and large industries. However, administrative controls were statistically lower in small and medium industries compared to the large industries. Moreover, screening was statistically lower in small industries than in large industries. The mean risk factors of ventilation, use of common tools and equipment, and physical distance as well as total risk factors were not statistically different among different industries. CONCLUSION: Workers are at risk of COVID-19 infection. The risk factors of ventilation, sharing tools and equipment, and physical distance are critical in classification of risk of infection with COVID-19 in industrial settings.

Assessing the risk of main activities of nanotechnology companies by the NanoTool method.

Purpose. Nanotechnology can be considered one of the greatest developments over the past few decades. Despite many applications of nanomaterials in various fields, there are concerns about their effects on humans and the environment. Therefore, this study was conducted to assess the risk level of activities involving nanomaterials in nanotechnology companies in Tehran, Iran. Materials and methods. After identifying the main activities of 18 nanotechnology companies, these activities were assessed using the NanoTool method, which is a method for assessing risks of activities involving nanomaterials. Data were analyzed using SPSS version 22. Results. The results showed that in six activities (33.30%) the risk level was 4 (RL4), in eight activities (44.40%) the risk level was 3 (RL3) and four activities (22.30%) had risk level 2 (RL2). Also, it was found that 78.88% of the controls used by these companies were not enough to reduce the risks of nanomaterials and need to be upgraded. Conclusions. The high level of risk in the activities involving nanomaterials shows that there are serious problems regarding the safety of nanomaterials in the nanotechnology companies in Tehran, Iran.

Identification, Selection and Prioritization of Key Performance Indicators for the Improvement of Occupational Health (Case Study: An Automotive Company).

Regarding the important role of occupational health in the continuous improvement of organizations, the aim of this study was to identify, select and prioritize key indicators for improvement of occupational health in an automotive company. This cross-sectional descriptive study was carried out in three stages. First, a semi-structured interview as well as an inspection and a review of the company's documentation and studies were carried out, and a set of key indicators were identified and selected. Then, the validity of the indicators were determined by experts (N = 11). Following that, the indicators were prioritized based on SMART criteria. Following the study framework, we collected a set of indicators that included 45 health indicators and 17 educational ones. The results of examining their content validity showed that among the 45 primary health indicators and 17 educational ones, 12 and 9 indicators had acceptable validity, respectively, and a total of 21 indicators were suggested for the purpose of the study by the expert team. The results of prioritizing showed that the leading indicator such as the percentage of corrective and preventive health actions done with the weight of 0.146 was the first priority. A set of key indicators was proposed according to the results, based on the objective of the study, which can help managers and industrial hygiene experts to assess performance in the automotive industry.

Oxidative/nitrosative stress, autophagy and apoptosis as therapeutic targets of melatonin in idiopathic pulmonary fibrosis.

INTRODUCTION: Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease associated with disruption of alveolar epithelial cell layer and expansion of fibroblasts/myofibroblasts. Excessive levels of oxidative/nitrosative stress, induction of apoptosis, and insufficient autophagy may be involved in IPF pathogenesis; hence, the targeting of these pathways may ameliorate IPF. Areas covered: We describe the ameliorative effect of melatonin on IPF. We summarize the research on IPF pathogenesis with a focus on oxidative/nitrosative stress, autophagy and apoptosis pathways and discuss the potential effects of melatonin on these pathways. Expert opinion: Oxidative/nitrosative stress, apoptosis and autophagy could be interesting targets for therapeutic intervention in IPF. Melatonin, as a potent antioxidant, induces the expression of antioxidant enzymes, scavenges free radicals and modulates apoptosis and autophagy pathways. The effect of melatonin in the induction of autophagy could be an important mechanism against fibrotic process in IPF lungs. Further clinical studies are necessary to determine if melatonin could be a candidate for treating IPF.

Selection of optimized air pollutant filtration technologies for petrochemical industries through multiple-attribute decision-making.

Selecting cost-effective and efficient air filtration technologies that ensure sustainable development is a challenge to national, regional and local policy makers. Various factors such as efficiency, maintainability, and design of the developed devices can affect the selection of optimized technologies. The present study aimed to select optimal technologies for air filtration devices in petrochemical industries through a multi-criteria decision-making (MADM) method based on a fuzzy model of Technique for Order of Preference by Similarity to Ideal Solution (TOPSIS). Five criteria (filtration efficiency, cost, maintainability, designability, and size) were used to rank air pollution control technologies designed to eliminate particulate matter (PM), volatile organic compounds (VOCs), and ammonia (NH3). According to the results, the research criteria had different weights for different air pollutants. High-efficiency particulate air (HEPA + pre collector) filters, plasma chemistry, and chemical absorption were identified as the most appropriate filtration methods for PM, VOCs, and NH3, respectively (coefficients = 0.923, 0.9586, and 0.867, respectively).

A Simple and Fast Method Based on New Magnetic Ion Imprinted Polymer as a Highly Selective Sorbent for Preconcentration and Determination of Cadmium in Environmental Samples.

BACKGROUND: The analysis of heavy metals at trace level is one of the main toxicologists concern, due to their vital rules in human`s life. Cadmium is one of these toxic heavy metals, which released to the environment from various industries. METHODS: In order to determine Cd (II) ions in various matrices magnetic ion-imprinted polymer (IIP) method has been developed and applied. This nano-sorbent has been synthesized by coating an IIP compound on Fe3O4 nanoparticles core to achieve highest surface area. This polymer has been used to evaluate Cd (II) levels in food, river, and wastewater in Tehran, Iran. RESULTS: Fe3O4@Cd-IIP was stable up to 300 °C. The various factors such as sample pH (optimized as 7), elution/sorption time (5 min), eluent amount (4 mL HCL), and its concentration (2 mol L-1) were optimized. Analysis instrument in all steps was Flame Atomic Abortion Spectrophotometer (FAAS). In this study, the detection limit was determined down to 0.6 µg L-1. CONCLUSION: This method was applied successfully for the preconcentration and determination of Cd (II) ions in environmental samples obtained from rivers, various foods and wastewater. In addition, the accuracy of the method was confirmed by analyzing a certified reference material (Seronorm LOT NO2525) and spiked real samples.

Health, safety and environmental risk management in laboratory fields.

BACKGROUND: Research project risks are uncertain contingent events or situations that, if transpire, will have positive or negative effects on objectives of a project. The Management of Health and Safety at Work (MHSW) Regulations 1999 require all employers and the self-employed persons to assess the risks from their work on anyone who may be affected by their activities. Risk assessment is the first step in risk-management procedure, and due to its importance, it has been deemed to be a vital process while having a unique place in the researchbased management systems. METHODS: In this research, a two-pronged study was carried out. Firstly, health and safety issues were studied and analyzed by means of ISO 14121. Secondly, environmental issues were examined with the aid of Failure Mode and Effect Analysis. Both processes were utilized to determine the risk level independently for each research laboratory and corrective measure priorities in each field (laboratory). RESULTS: Data analysis showed that the total main and inherent risks in laboratory sites reduced by 38% to 86%. Upon comparing the average risk levels before and after implementing the control and protective actions utilizing risk management approaches which were separate from health, safety and environmental aspects, a highly effective significance (p<0.001) was obtained for inherent risk reduction. Analysis of health, safety and environmental control priorities with the purpose of comparing the ratio of the number of engineering measures to the amount of management ones showed a relatively significant increase. CONCLUSION: The large number of engineering measures was attributed to the employment of a variety of timeworn machinery (old technologies) along with using devices without basic protection components.

Health, safety, and environmental management system operation in contracting companies: A case study.

Systematic and cooperative interactions among parent industry and contractors are necessary for a successful health, safety, and environmental management system (HSE-MS). This study was conducted to evaluate the HSE-MS performance in contracting companies in one of the petrochemical industries in Iran during 2013. Managers of parent and contracting companies participated in this study. The data collection forms included 7 elements of an integrated HSE-MS (leadership and commitment; policy and strategic objectives; organization, resources, and documentation; evaluation and risk management; planning; implementation and monitoring; auditing and reviewing). The results showed that mean percentage of the total scores in seven elements of HSE-MS was 85.7% and 87.0% based on self-report and report of parent company, respectively. In conclusion, this study showed that HSE-MS was desirably functioning; however, improvement to ensure health and safety of workers is still required.

Educational intervention for reducing work-related musculoskeletal disorders and promoting productivity.

BACKGROUND AND OBJECTIVES: Work-related musculoskeletal disorders (WMSDs) are the main causes of pain, suffering, absenteeism, disability and reduction in productivity. This research aims to determine the role of training intervention based on protection motivation theory in reducing WMSDs and promoting productivity. METHODOLOGY: The conducted study was based on a quasi-experimental design (control) that was carried out on 158 employees of the Kabl Khodro factory which were divided into two groups of 79 people. After splitting the 158 workers, an experimental and control group was formed. The data collection instruments were made up of two questionnaires and were analysed using a quick exposure check (QEC) method. RESULT: Before intervention in both the experimental and control groups, there were no significant differences among the average protection motivation theory constructs, productivity and QEC scores (p < 0.05). However, following training intervention there was a significant increase in these factors within the investigated group apart from the perceived response costs and efficacy. CONCLUSION: The conducted study shows that ergonomic training based on the protection motivation theory is effective in reducing musculoskeletal risk factors and that increased knowledge of the subject can lead to an increase in productivity.

Enhanced performance of non-thermal plasma coupled with TiO2/GAC for decomposition of chlorinated organic compounds: influence of a hydrogen-rich substance.

BACKGROUND: No study was found in the literature on the combination of TiO2/GAC catalyst and non-thermal plasma for chlorinated volatile organic compounds abatement in air. This paper presents this hybrid process for the decomposition of chloroform (as a target compound) using a multi-pin to plate discharge reactor. The experiments were performed using a high frequency pulsed transformer as the power supply system to examine the effect of SIE, frequency, as well as initial concentration on the chloroform removal efficiency (RE). Toluene was added as a hydrogen-rich source to shift the reactions into the formation of environmentally desirable products. RESULTS: RE of around 60% was observed with the NTP-alone process at the highest possible SIE (3000 J L(-1)), while it rocketed up to 100% (total oxidation) in the presence of TiO2/GAC at SIE of 1000 J L(-1). About 100% O3 destruction over TiO2/GAC and both adsorption and catalytic activities of GAC may be considered as the reasons for better performance of the hybrid process. Toluene feeding diminished the chlorinated by-products such as Cl2 and TCE significantly. The selectivity towards CO2 was noticed to enhance noticeably, when both catalyst and toluene were introduced, regardless of the input concentration. CONCLUSIONS: Our findings suggest that the hybrid of NTP with TiO2/GAC will highly be effective in the abatement of chloroform, and the addition of toluene will successfully decline harmful chlorinated by-products.