Age differences in the impact of dietary salt on metabolism, blood pressure and cognitive function in male rats.

The influence of salt consumption on physiological processes, especially blood pressure (BP), metabolism, and cognition, remains a topical concern. While guidelines endorse reduced salt diets, there are gaps in understanding the age-specific implications and challenges in adherence. The present study delved into the differential effects of salt intake on young adult and aged male rats over a 12-week period, using control, low-, and high-salt diets. Key metrics, such as BP, cognition, and general parameters, were monitored. Our findings revealed significant age-dependent effects of salt intake on survival rates, body weight, blood sodium, blood glucose, blood lipids, BP, heart rates, and cognition. Notably, young adult rats did not show significant sodium level changes on a high-salt diet, whereas aged rats experienced increased sodium levels even on a normal salt diet. Blood glucose levels decreased significantly in aged rats on a high-salt diet but remained stable in young adults. Aged rats had the highest survival rates on low-salt diets. Low-salt diets led to reduced BP in both age groups, more significantly in young adults. Young adult rats displayed increased BP variability on both high- and low-salt diets, while a decrease in BP variability was exclusive to aged rats on a low-salt diet. There were significant differences across age groups in short-term memory, but not in long-term memory. The study provides a nuanced understanding of the age-dependent physiological effects of salt intake, suggesting the necessity of age-specific guidelines for public health.

A Robust Cage-Based Metal-Organic Framework Showing Ultrahigh SO2 Uptake for Efficient Removal of Trace SO2 from SO2/CO2 and SO2/CO2/N2 Mixtures.

Removal of trace SO2 from an SO2-containing product is now receiving increasing attention. However, designing a robust porous adsorbent with high SO2 adsorption capacity and good SO2/CO2 selectivity, as well as validity under humid conditions, is still a challenging task. Herein, we report a porous cage-based metal-organic framework, namely ECUT-111, which contains two distinct cages with apertures of 5.4 and 10.2 Å, respectively, and shows high a BET of up to 1493 m2/g and a pore volume of 0.629 cm3/g. Impressively, ECUT-111 enables an ultrahigh SO2 uptake of up to 11.56 mmol/g, exceeding most reported top-performing adsorbents for such a use. More importantly, complete separation of trace SO2 from SO2/CO2 and SO2/CO2/N2 mixtures, especially under humid conditions, and excellent recycle use were observed for ECUT-111, suggesting its superior application in desulfurization of SO2-containing products.

High Adsorption Capacity and Selectivity of SO2 over CO2 in a Metal-Organic Framework.

Herein, we report a new metal-organic framework (MOF), namely, ECUT-77, which is built on rod-shaped secondary building units, showing a high Brunauer-Emmett-Teller surface area of 760.3 cm2/g, a pore volume of 0.4 cm3/g, and an aperture of about 1 nm. This MOF enables both high SO2 adsorption capacity up to 8.0 mmol/g at 0.92 bar and room temperature and a high SO2/CO2 selectivity of 44, resulting in excellent SO2 separation upon a ECUT-77 column from a SO2/CO2 mixture containing 2000 ppm of SO2.

General Approach for Constructing Mechanoresponsive and Redox-Active Metal-Organic and Covalent Organic Frameworks by Solid-Liquid Reaction: Ferrocene as the Versatile Function Unit.

We report for the first time the construction of mechanoresponsive and redox-active metal-organic frameworks (MOFs) and covalent organic frameworks (COFs) by anchoring ferrocene (Fc) pendants as mechanophores in the pore wall. This work outlines a simple, general, and low-cost route to tailor MOFs and COFs by a Fc unit for mechanoresponsive nature, the release of Fe ions, redox behavior, and modulation of the skeleton charge together.