A Multicenter Study to Determine Knowledge and Perceptions on Stem Cell Donation, Transplantation Among Saudi Medical Students.

BACKGROUND: Despite significant contributions to stem cell research in Saudi Arabia, knowledge and awareness of stem cell research is the subject of ongoing studies with controversial findings, specifically among medical students. This was a cross-sectional study with 685 medical students aimed to explore their knowledge and attitudes in relation to stem cell research and transplantation. METHODS: A validated survey exploring knowledge and attitudes in relation to stem cell research and transplantation was administered. The total knowledge, attitude, and age scores were presented through mean and SD RESULTS: The results of the present study showed that university students in the Eastern Province had an average 35.88 knowledge of stem cell research. In contrast, the attitudes were positive among the entire study sample, with a mean of 3.79 out of 5. Both men and women had significant knowledge about the definition of stem cells and adult stem cells, bone marrow, whether stem cells can be used for drug testing, and recommended stem cell treatment if available. CONCLUSIONS: The medical curriculum needs to be refined and enriched with additional data on organ and stem cell donation. This can be further enriched with experimental evidence through additional training initiatives that will allow those with negative attitudes to re-evaluate their perceptions and provide accurate information to patients as future health care providers.

A literature review of carpal tunnel syndrome and its association with body mass index, wrist ratio, wrist to palm ratio, and shape index.

STUDY DESIGN: Systematic literature review of case-controlled studies. INTRODUCTION: Carpal tunnel syndrome (CTS) is one of the most common tubular neuropathies where certain anatomical variations may be accounted for as risk factors for CTS, including body mass index (BMI), wrist ratio (WR), wrist to palm ratio (WPR), shape index (SI), and digit length. PURPOSE OF THE STUDY: To assess case-control studies examining the association between specific anatomical variations of the wrist as risk factors for developing CTS and whether this effect is the same for both genders. METHODS: The literature search was conducted between February-June 2020 through PubMed, Cochrane Library, CINAHL Plus and PEDro. The literature search yielded 149 potential publications, fifteen of which were filtered in accordance with eligibility criteria. The methodological quality was assessed by using the Newcastle-Ottawa Quality Assessment Form for Case-Control Studies (NOS). RESULTS: The total number of subjects included in this review was n=4299. The largest sample was n=1117 participants and the smallest n=54. All studies included patients who had a clinical diagnosis of CTS confirmed with nerve conduction studies and or ultrasonography. CTS was significantly higher in patients with higher BMI, WR, WPR compared to control groups. BMI and WR were the only indicators that can be considered as strong risk factors. CONCLUSIONS: Discussion: Despite the general patterns on the association of BMI, WPR, WR and SI as risk factors for the development of CTS, there were exceptions to the accepted results and conclusions. CONCLUSION: Clinicians are recommended to conduct more research to confirm anthropometric measurements as risk factors for the development of CTS, mainly SI and WPR. When determining the cut-off values for BMI and WR, it is recommended to take into account additional risk factors such as occupation.

Knowledge, Attitude, and Behavior Toward Organ Donation and Transplantation Among Medical Students in the Eastern Province of Saudi Arabia.

BACKGROUND: Organ donation is an integral part of medical ethics worldwide, including Saudi Arabia. Although the Saudi community has a positive attitude toward the concept of organ donation and transplantation, several factors prevent people from agreeing to donate organs and tissues. This study aimed to explore and evaluate the knowledge and attitudes medical students in the Eastern Province of Saudi Arabia have toward organ donation and transplantation. METHODS: A cross-sectional study among 722 medical students in the Eastern Province. The questionnaire consisted of 3 parts: sociodemographic questions, organ donation and transplantation knowledge questions, and questions on attitudes toward organ donation and reasons for consenting or refusing to donate. RESULTS: Both men and women had positive attitudes toward organ donation. The level of knowledge of organ donation and related procedures did not differ significantly among men (13.07%) and women (13.60%) (P < .027). The motives for donation were the desire to help others (88.8%) (P = .02) and sympathy (59.8%). The main source of information on organ donation for respondents was television, followed by the internet and relatives and/or friends. CONCLUSIONS: While medical students are generally supportive of organ donation and transplantation, they may lack basic knowledge on organ donation. Due to lack of basic knowledge, they become hesitant to make the decision to donate. It is recommended that additional organ donation modules be included in the student curriculum to increase the knowledge of future health care providers. Most of the participants would not change their attitudes toward organ donation based on the Saudi government initiatives to register for the Saudi Center for Organ Transplantation organ donation program.