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1.
Ukr Biokhim Zh (1999) ; 71(3): 104-7, 1999.
Artículo en Ucraniano | MEDLINE | ID: mdl-10609334

RESUMEN

The normal catalytic activity of insects cholinesterases was determined: Apanteles glomeratus L., Coccinella septempunctata L., Rhopalosiphum padi L. and Pieris brassicae L. Constants of bimolecular interaction of three insecticides for insects were calculated: cholinesterase of C. septempunctata were the most sensitive to Bi-58 new [Kii = (4.54 +/- 0.23). 10(4)], cholinesterase of aphids was revealed to be the most sensitive to acetec [Kii = (2.9 +/- 0.14). 10(5)]. The studies have been carried aimed to determination of anticholinesterase actioncoefficients: acetec demonstrated the selective anticholinesterase activity in the system Aphididae--Coccinellidae (Kache = 118.9). Its anticholinesterase activity underlies in the toxicity mechanism for the given species.


Asunto(s)
Inhibidores de la Colinesterasa/farmacología , Insectos/efectos de los fármacos , Insecticidas/farmacología , Compuestos Organofosforados , Virus de Plantas/efectos de los fármacos , Piretrinas/farmacología , Animales , Catálisis , Colinesterasas/metabolismo , Insectos/enzimología , Virus de Plantas/enzimología
2.
Probl Tuberk ; (2): 44-5, 1997.
Artículo en Ruso | MEDLINE | ID: mdl-9235590

RESUMEN

The paper shows the value of the activities of a medical sanitary detachment from the complex expedition of the USSR Academy of Sciences (1925-1930) in the development of surgical treatment for bone and joint tuberculosis and its sequelae in adults from Yakutia. A total of 981 operations were made from 1951 to 1994. Priorities were given to timely surgical interventions, including radical reparative spinal and joint operations, by using the Ilizarov apparatus.


Asunto(s)
Expediciones/historia , Asociaciones de Lucha contra la Tuberculosis/historia , Tuberculosis Osteoarticular/cirugía , Academias e Institutos , Adulto , Historia del Siglo XX , Humanos , U.R.S.S.
3.
Genetika ; 16(12): 2217-25, 1980.
Artículo en Ruso | MEDLINE | ID: mdl-6453040

RESUMEN

In 28 families with G6PD deficiency living in 3 settlements of Shekii district of Azerbaijan 11 G6PD variants of II and III classes differing by kinetic properties were identified according WHO program. 9 of them are characterized with the same electrophoretic mobility. Comparison of G6PD spectra in two subpopulations and in a mixed group permits to make a conclusion about existence of common and rare G6PD alleles in examined population. They distribute by gene drift supported by natural selection. Among 7 samples of G6PD with normal and increased activity two new variants of IV class -- Nukha and Bash-Kungut -- were found.


Asunto(s)
Alelos , Glucosafosfato Deshidrogenasa/genética , Mutación , Azerbaiyán , Activación Enzimática , Eritrocitos/enzimología , Genética de Población , Deficiencia de Glucosafosfato Deshidrogenasa/genética , Heterocigoto , Humanos , Polimorfismo Genético
4.
Genetika ; 13(8): 1455-61, 1977.
Artículo en Ruso | MEDLINE | ID: mdl-144081

RESUMEN

Examination on G6PD deficiency in 349 patients of Shekii district hospital (Azerbaijan) revealed 16 hemi-, 4 homo- and 9 heterozygotic carriers of the defect. Gd- frequency, calculated from the data obtained (7.7%), may be compared to neighbouring regions' frequencies (6-30%). Carriers of G6PD deficiency are residents of 11 villages located in Alasani-Aphtalan valley, highly endemic with malaria in the past; nearly all marriages are endogamic. Physico-chemical and kinetic study of 10 mutant forms of G6PD, according to WHO program, led to identification of 5 variants of the II class (Shekii, Bideiz, Shirin-Bulakh, Okhut I and Zakataly) and 2 variants of the III class (Okhut II and Martinique-like). Resemblance of the majority of variants in electrophoretic mobility and the level of erythrocyte enzyme activity permit to suggest the existence of a common parental mutant G6PD allele distributed in this area.


Asunto(s)
Deficiencia de Glucosafosfato Deshidrogenasa/genética , Alelos , Azerbaiyán , Eritrocitos/enzimología , Femenino , Variación Genética , Glucosafosfato Deshidrogenasa/genética , Deficiencia de Glucosafosfato Deshidrogenasa/sangre , Heterocigoto , Homocigoto , Humanos , Masculino , Mutación , Linaje
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