[The differential diagnostic significance of the binding capacity of serum immunoglobulins with amino acids in rheumatism, rheumatoid arthritis and systemic lupus erythematosus with a minimal degree of activity]. / Differentsial'no-diagnosticheskoe znachenie sviazyvaiushchei sposobnosti syvorotochnykh immunoglobulinov s aminokislotami pri revmatizme, revmatoidnom artrite i sistemnoi krasnoi volchanke s minimal'noi stepen'iu aktivnosti.

The ability of immunoglobulins (Ig) G, A and M to bind to amino acids was studied in 27 patients with rheumatism (R), 28 with rheumatoid arthritis (RA) and 27 patients with systemic lupus erythematosus (SLE) with minimum degree of activity. The enhancement of the binding capacity of IgG with respect to arginine, glutamic acid, lysine and decrease of that of IgM towards serine was established to be of diagnostic value in R as was the enhancement of the above capacity of IgG and A with respect to proline and oxyproline in RA and enhancement of that of Ig of all three classes with respect to a broad range of amino acids in SLE. Information criteria were established of differential diagnosis of R, RA and SLE.

[The amino acid-binding capacity of immunoglobulins in rheumatoid arthritis patients]. / Sviazyvaiushchaia sposobnost' immunoglobulinov s aminokislotami u bol'nykh revmatoidnym artritom.

A study is presented of the binding capacity of immunoglobulins with amino acids in 60 patients with rheumatoid arthritis of grade I and II activity. Results of the investigation revealed an increase of the binding capacity of immunoglobulins of all three classes with a high range of amino acids that depended directly on the activity grade of the pathological process.

[The diagnostic significance of the binding capacity of immunoglobulins with amino acids in torpid rheumatism]. / Diagnosticheskoe znachenie sviazyvaiushchei sposobnosti immunoglobulinov s aminokislotami pri vialo tekushchem revmatizme.

The authors studied the binding capacity of immunoglobulins (Ig) in torpid rheumatism. An increase was established of the binding capacity of IgG with glutamic acid and arginine and reduction of the binding capacity of IgM with serine. The degree of increase of the binding capacity of Ig with amino acids was 2.2 times higher than increase of the Ig level which may be a more sensitive index of activity of the rheumatic process.

[Effects of sulfalene on the thymus, spleen and adrenals in an experiment]. / Vliianie sul'falena na timus, selezenku i nadpochechniki v éksperimente.

The effect of sulfalen on the weight and structure of the thymus, spleen and adrenal glands was studied. The findings were compared with the results observed in control rats. It was shown that after administration of sulfalen, the weight of the adrenal glands markedly decreased while their structure did not change. Thymus specimens showed a large number of hypertrophic epitheliocytes, in the medulla which was accompanied by a decrease in its weight.

[Effect of pentoxyl, ibuprofen and acetylsalicylic acid on the thymus, spleen and adrenals in an experiment]. / Deistvie pentoksila, ibuprofena i atsetilsalitsilovoi kisloty na timus, selezenku i nadpochechniki v éksperimente.

The effect of acetylsalicylic acid, ibuprofen and pentoxyl on the histological and morphometric pattern of the thymus and the weight of the thymus and spleen was studied in rats. There was decreased function of the thymus and its atrophy with acetylsalicylic acid and ibuprofen. Pentoxyl increased the secretory activity of the thymus. The effect of the drugs on the thymus and spleen was unidirectional.

[The binding capacity of serum immunoglobulins with amino acids in systemic lupus erythematosus]. / Sviazyvaiushchaia sposobnost' syvorotochnykh immunoglobulinov s aminokislotami pri sistemnoi krasnoi vo9lchanke.

The content of G, M, A, serum immunoglobulins and binding capacity with amino acids prolin, oxyprolin, alanin and serin was examined in 40 patients with systemic lupus erythematosus (grade I and II activity). It was established that the degree of increase of the binding capacity of Ig with amino acids was higher than that of corresponding Ig and depended on the activity of the process.