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Background: Breasts are considered one of the most physically and sexually appealing features of the female body. Reduction/augmentation techniques have greatly evolved in the last decades.We are reporting our experience with an innovative technique for mastopexy that recovers the aesthetics of the breast and avoids over-resection of its lower pole. Methods: Inclusion criteria were women who underwent kite mastopexy with or without implants between January 2018 and May 2022 in a single center (Bogota, Colombia). Exclusion criteria were patients with American Society of Anesthesiology score more than II, with any uncontrolled chronic illness and/or medical history of diabetic mellitus, metabolic syndrome, body mass index more than 32 kg per m2, and active smokers. Results: We found 133 consecutive female patients. Age range was 18 and 67 years (median 39). Breast implants were used for the purpose of kite mastopexy in 52% cases. Patients were divided into two groups: implants (group 1) versus no implants (group 2). Procedure 1 involved mastopexy without implants; procedure 2 included current implant users who underwent either implant removal or in whom implants were not used for the sake of mastopexy. Procedures 3 and 4 included patients who underwent either new implant placement or implant exchange, respectively. Average time of surgery was 1.5 hours. Minor complications were mostly related to wound dehiscence. No major complications were reported. Conclusions: Kite mastopexy restores the breast aesthetics by following specific markings, a new plication of breast pillars, and a reduced scar. Our technique demonstrates a very low rate of complications while entailing natural and appealing results.
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Radiofrequency is frequently used for skin rejuvenation, localized fat elimination and cellulite treatment. It prompts the expression of thermal shock proteins that lead to dermal thickening as a result of collagen synthesis. The authors report a histological and clinical analysis of the arm subdermal changes before and after bipolar radiofrequency treatment plus liposuction to determine their benefits for arm contouring. Methods: Inclusion criteria included patients with stage 1, 2a, and 2b brachial ptosis (Duncan classification) and upper limb fat deposits who were considered candidates for third-generation ultrasound-assisted liposculpture plus radiofrequency-assisted lipolysis/skin tightening. Arm subdermal tissue samples (5 mm³) were analyzed before and after the intervention. We used 10% formaldehyde for tissue fixation and stained each sample with hematoxylin/eosin, Masson trichrome, and antibody markers against the cell cycle Ki-67 protein. Results: We analyzed a total of 12 biopsies from six patients who meet the inclusion/exclusion criteria. Histological findings with hematoxylin/eosin revealed hyperplastic and metaplastic changes with focal distribution within the papillary and reticular dermis. Masson trichrome staining showed an increase of the characteristic basophilia of thin type-I and type-III collagen fibers. In contrast, molecular analysis reported an increase in fibroblast activity mediated by the activation of the heat shock protein HSP47. Conclusion: Radiofrequency may be a great alternative to improve skin retraction in patients with mild to moderate brachial dermatochalasis through the activation of HSP47 heat shock protein and the production of type-I and type-III collagen.
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RESUMEN Introducción. La pandemia del COVID-19, ocasionada por SARS-CoV-2, aumenta de manera exponencial, afectando el sistema de salud, la economía y poniendo en riesgo la vida de miles de personas por las características de contagio, además de la posibilidad de compromiso severo en adultos mayores e individuos inmunocomprometidos. Objetivos. Realizar una revisión en la literatura que aborde diferentes aspectos de la pandemia del COVID-19, dirigido a los profesionales de las ciencias de la salud o de otras disciplinas interesados en adquirir conocimientos sobre el SARS-CoV-2 con una visión integral. Materiales y métodos. Se realizó una búsqueda en la literatura utilizando términos Mesh en las siguientes bases de datos: Pubmed, Ovid, Clinical Key, Science Direct, para su análisis y selección de acuerdo con su relevancia en nuevos aportes. Resultados. Se evaluaron diversos estudios de cohortes, investigaciones clínicas experimentales, guías interinas de práctica de diversos organismos como el CDC y WHO, en donde se identifican las características epidemiológicas del patógeno, los estudios en CoVs previos, así como también los lineamientos preventivos, éticos y evaluación de fármacos ante el CO-VID-19. Conclusiones. Conocer el origen del patógeno, estructura, modo de transmisión, adecuada selección dentro de los criterios diagnósticos, entre otros puntos claves que contribuyen en el fortalecimiento de nuevas medidas preventivas y terapéuticas que puedan llegar a ser implementadas por el personal sanitario, generando mejoras en la atención de los pacientes con posible diagnóstico de COVID-19.
ABSTRACT Introduction. The COVID-19 pandemic, caused by SARS-CoV-2, increases exponentially, affecting the health system, the economy and putting at risk the lives of thousands of people due to the characteristics of contagion, in addition to the possibility of severe compromise in older adults and immunocompromised individuals. Objective. Carry out a review of the literature that addresses different aspects of the COVID-19 pandemic, aimed at professionals in the health sciences or other disciplines, interested in acquiring knowledge about SARS-CoV-2 with a comprehensive vision. Methods. A literature search was conducted using Mesh terms in the following databases: Pubmed, Ovid, Clinical Key, Science Direct for analysis and selection according to their relevance in new contributions. Results. Various cohort studies, experimental clinical studies, as well as interim practice guidelines from various agencies such as the CDC and WHO were evaluated, identifying the epidemiological characteristics of the pathogen from December 2019 to the present, as well as studies on previous CoVs, preventive guidelines and evaluation of drugs against COVID-19. Conclusion. Know the origin of the pathogen, structure, mode of transmission, adequate selection within the diagnostic criteria, among other key points that contribute to the strengthening of new preventive and therapeutic measures that may be implemented by health personnel, generating improvements in the care of patients with possible diagnosis of COVID-19.
