Fusariosis in the Sphere.

In 2012, the US Centers for Disease Control and Prevention reported a fungal meningitis outbreak due to Exserohilum rostratum, caused by methylprednisolone administration. Twelve years later, an iatrogenic outbreak of Fusarium meningitis was documented in Mexico after epidural anesthesia.

Fusariosis in Mexico: A 10-year retrospective series.

Fusarium species represent an opportunistic fungal pathogen. The data in Mexico about Fusarium infections in humans are scarce. Here, we present a retrospective series of patients with a confirmed diagnosis of fusariosis in eight different hospitals in Mexico from January 2010 to December 2019. The diagnosis of proven fusariosis was made according to the European Organization for Research and Treatment of Cancer and the Mycoses Study Group Education and Research Consortium (EORT/MSG) criteria. A total of 49 cases were identified in our series. Most patients had burn injuries (49%), and 37% had hematological malignancies. Most patients had fire injuries (40%), followed by electric injuries (8%), febrile neutropenia (10%), and pancytopenia (6%). Patients had skin and soft tissue involvement in 49%, followed by blood culture isolation and biopsies from different sites of the body (lung, sinuses, bone tissue, and eyes). Febrile neutropenia (10%) and fungemia (8%) were the most common clinical syndromes in immunosuppressed patients. Most patients received monotherapy (67%), where voriconazole was used in 30% of the cases, followed by conventional amphotericin B (16%), and lipidic formulations of amphotericin B in 10% (either liposomal amphotericin B or amphotericin B lipid complex). Combination therapy was used in 20% of the cases, and the most common combination therapy was triazole plus any lipidic formulation of amphotericin B (10%). Mortality related to Fusarium infection occurred in 22% of patients. Fusariosis is a serious threat. Burn injuries and hematologic malignancies represent the most common causes of infection in this small series from Mexico.

This study describes the epidemiological characteristics of patients with fusariosis from a multicenter cohort in Mexico. These findings provide information from this invasive fungal disease that threatens different countries in Latin America.

Clostridioides Difficile in Latin America: An Epidemiological Overview.

Clostridioides difficile infection is one of the most significant causes of nosocomial diarrhea associated with antibiotic use worldwide. In recent years, the incidence of Clostridioides difficile infection in Latin American countries has increased due to the emergence and spread of epidemic Clostridioides difficile strains, such as RT027/NAP1/ST1, RT078/ST11, and RT017/ST37; additionally, endemic multi-drug-resistant strains have recently appeared due to the lack of heterogeneous diagnostic algorithms and guidelines for antibiotic use in each country. The aim of this review is to present the latest information regarding Clostridioides difficile and emphasize the importance of epidemiological surveillance of this pathogen in Latin American countries.

Teorias subjetivas da convivência escolar: o que os pais dizem? / Teorías subjetivas de la convivencia escolar: ¿qué dicen los padres / Subjective theories about school coexistence: what do parent say?

El objetivo de este trabajo fue describir e interpretar las TS de la convivencia escolar, de un grupo de padres y madres de una escuela de educación primaria chilena. Se utilizó un muestreo teórico y se aplicaron grupos de discusión y entrevistas episódicas a 16 padres y madres de una escuela de educación primaria. Los datos se analizaron mediante la técnica de la teoría fundamentada, encontrando (a) teorías subjetivas simples, pero que disponen a los padres a educar a sus hijos en convivencia; (b) factores asociados a la CE y propuestas para su mejora, (c) además de un rol parental educativo que se organiza en tres niveles para enseñar a sus hijos a convivir en la escuela. En la discusión se analiza la implicancia de estas teorías subjetivas en la convivencia escolar y el rol parental.

O objetivo deste trabalho foi descrever e interpretar as teorias subjetivas (TS) da convivência escolar (CE), de um grupo de pais e mães de uma escola de educação primária chilena. Uma amostragem teórica foi utilizada e se aplicaram grupos de discussão e entrevistas episódicas em 16 pais e mães de uma escola de educação primária. Os dados foram analisados através da técnica da teoria fundamentada (Grounded Theory), encontrando: (a) teorias subjetivas simples, mas que proporcionam aos pais educar seus filhos na convivência; (b) fatores associados à CE e propostas de melhoria; (c) além de um papel educativo dos pais que se organiza em três níveis para ensinar seus filhos a conviver na escola. Na discussão é analisada a implicação das teorias subjetivas na convivência escolar e no papel parental.

The aim of this work was to describe and to interpret subjective theories about school coexistence in a group of parents from a Chilean primary school. A theoretical sample was used, group discussions and episodic interviews were conducted to 16 parents from a primary school. Data was analyzed through grounded theory, finding (a) simple subjective theories lead parents to raise their children on an environment-based approach; (b) associated factors with school coexistence environment and emerging proposals to improve them; (c) as well as a schooling parental role that it organizes around three levels of climate schooling teaching. In the discussion section, we analyze implications of these subjective theories into schooling environment and parental role.

COVID-19 y comportamiento psicológico: revisión sistemática de los efectos psicológicos de las pandemias del siglo XXI

The aim of this work was to conduct a systematic review on psychological behavior in the context of pandemic scenarios during the twenty-first century. We focused on empirical works and brief case reports of H1N1 flu and COVID-19. Our review included 32 papers published both in English or Spanish. We built a set of tables that allowed us to classify the information in four main categories, namely the psychological impact of the pandemic, whether people follow or not official measures to protect themselves against the pandemic, psychological adherence considerations implied as mediators to respect official strategies, and relevant methodological characteristics of the pandemic research. Results show that there are significant impacts on the psychological behavior of people, social groups and organizations in several dimensions, namely emotion, cognition, behavior, mental health, organization and psychosocial factors. In addition, we found that certain social groups experienced a critical psychosocial impact likely due to the pandemic. Psychosocial factors affecting adherence were also identified, which allow us to better understand how health strategies are followed by the population. Different psychosocial suggestions, which emerged from the papers reviewed, were systematized and should be considered as possible pandemic strategies to be implemented.

The damage of the Watson-Crick base pairs by nickel nanoparticles: A first-principles molecular dynamics study.

The nickel nanoparticles are harmful atmospheric pollutants, and the damage caused by them in humans has become a topic of great relevance. In this study we investigate the interaction of the Ni2 and Ni3 clusters with the AT and GC Watson-Crick base pairs in an aqueous medium. Molecular dynamics in combination with density functional theory are employed. A novel method is implemented to create realistic thermodynamic conditions (NVT) in the simulations. The energies, the charges of the interacting compounds, the temperature changes, and the geometric rearrangements are reported. The results show the formation of stable organometallic compounds of the nickel nanoparticles with the DNA nucleic acid bases. In this respect, the biological processes where the DNA is implicated may be altered by the formation of such super-structures.

Bone scan positivity in non-metastatic, castrate-resistant prostate cancer: external validation study

ABSTRACT Introduction: Tables predicting the probability of a positive bone scan in men with non-metastatic, castrate-resistant prostate cancer have recently been reported. We performed an external validation study of these bone scan positivity tables. Materials and Methods: We performed a retrospective cohort study of patients seen at a tertiary care medical center (1996-2012) to select patients with non-metastatic, castrate-resistant prostate cancer. Abstracted data included demographic, anthropometric, and disease-specific data such as patient race, BMI, PSA kinetics, and primary treatment. Primary outcome was metastasis on bone scan. Multivariable logistic regression was performed using generalized estimating equations to adjust for repeated measures. Risk table performance was assessed using ROC curves. Results: We identified 6.509 patients with prostate cancer who had received hormonal therapy with a post-hormonal therapy PSA ≥2ng/mL, 363 of whom had non-metastatic, castrate-resistant prostate cancer. Of these, 187 patients (356 bone scans) had calculable PSA kinetics and ≥1 bone scan. Median follow-up after castrate-resistant prostate cancer diagnosis was 32 months (IQR: 19-48). There were 227 (64%) negative and 129 (36%) positive bone scans. On multivariable analysis, higher PSA at castrate-resistant prostate cancer (4.67 vs. 4.4ng/mL, OR=0.57, P=0.02), shorter time from castrate-resistant prostate cancer to scan (7.9 vs. 14.6 months, OR=0.97, P=0.006) and higher PSA at scan (OR=2.91, P <0.0001) were significantly predictive of bone scan positivity. The AUC of the previously published risk tables for predicting scan positivity was 0.72. Conclusion: Previously published risk tables predicted bone scan positivity in men with non-metastatic, castrate-resistant prostate cancer with reasonable accuracy.

Frecuencia de posiciones de terceros molares impactados en pacientes atendidos en la IPS CES-Sabaneta - Antioquia / Frequency of impacted third molar positions in patients treated in the IPS CES-Sabaneta-Antioquia / Frequência de posições de terceiros molares impactos em pacientes atendidos no IPS CES-Sabaneta - Antioquia

Resumen Introducción y Objetivo: La impactación de terceros molares es una situación clínica muy común en la población mundial; Pell & Gregory han sugerido una clasificación para la impactación basados en la posición horizontal y vertical. Identificar la frecuencia de posiciones de terceros molares impactados en pacientes atendidos en la clínica CES-Sabaneta entre los años 2006-2016. Materiales y métodos: De acuerdo a la base de datos del servicio de cirugía oral, dos examinadores durante 3 meses revisaron 626 historias clínicas en pacientes entre 17 a 28 años de edad que tuvieran formula dental completa, con radiografía panorámica y que fueron remitidos por motivos ortodónticos, restaurativos o quirúrgicos. Resultados: Un total de 515 terceros molares fueron evaluados, el tercer molar más impactado fue el 28 (25,6%), seguido del 18 (25,4%), el 48 con 24,6% y el 38 con 24,2%. Prevaleció el género femenino con 58,6%, el diente más impactado fue el 28 (87.8%), a nivel vertical la posición C fue la que más se impactó, mientras que en los hombres el diente más impactado es el 18 con un 79.7%, la posición B fue la más impactada y a nivel horizontal la clase II fue la más común en ambos sexos. Conclusión: A nivel vertical la posición B, fue la más frecuente en los terceros molares del género femenino, sin embargo, en el género masculino hubo una variación, en el maxilar predomino la posición C; a nivel horizontal la clase II fue las posiciones más frecuentes en ambos géneros.

Abstract Introduction and objective: The Impaction of third molars is a very common clinical situation in the world population; Pell & Gregory have suggested a classification for impaction based on horizontal and vertical position. To identify the frequency of impacted third molar positions in patients treated at the CES-Sabaneta clinic between the years 2006-2016. Materials and methods: According to the oral surgery service database, two examiners during 3 months reviewed 626 clinical histories in patients between 17 and 28 years of ages who had complete dental formula, with panoramic radiography and who were remitted for reasons orthodontic, restorative or surgical. Results: A total of 515 third molars were evaluated, the third most impacted molar was 28 (25.6%), followed by 18 (25.4%), 48 with 24.6% and 38 with 24.2%. %. The female gender prevailed with 58.6%. The most impacted tooth was 28 (87.8%). At the vertical level, position C was the most impacted, while in men the most impacted tooth is 18 with a 79.7. %, position B was the most impacted and at the horizontal level class II was the most common in both sex. Conclusions: At the vertical level, position B was the most frequent in the third molars of the female gender, however in the male gender there was a variation, in the maxillary the position C predominated; A horizontal level class II was the most frequent positions in both sex.

Sumário Introdução e Objetivo: O impacto dos terceiros molares é uma situação clínica muito comum na população mundial; Pell & Gregory sugeriram uma classificação para o impacto com base na posição horizontal e vertical. Identifique a frequência de comprometimento das posições dos terceiros molares em pacientes tratados na clínica CES-Sabaneta entre 2006-2016. Materiais e métodos: Segundo o banco de dados do serviço de cirurgia oral, dois examinadores, durante 3 meses, revisaram 626 prontuários em pacientes entre 17 e 28 anos de idade que possuíam fórmula dental completa, com radiografia panorâmica e foram encaminhados por motivos ortodôntico, restaurador ou cirúrgico. Resultados: Foram avaliados 515 terceiros molares, o terceiro molar mais impactado foi 28 (25,6%), seguido por 18 (25,4%), 48 com 24,6% e 38 com 24,2 % O sexo feminino prevaleceu com 58,6%, o dente mais impactado foi 28 (87,8%), no nível vertical a posição C foi a mais impactada, enquanto nos homens o dente mais impactado é 18 com 79,7%. %, posição B foi a mais impactada e horizontalmente a classe II foi a mais comum em ambos os sexos. Conclusão: No nível vertical, a posição B foi a mais frequente nos terceiros molares do sexo feminino, no entanto, no sexo masculino houve variação, na posição maxilar C predominou; horizontalmente, a classe II foi a posição mais frequente em ambos os sexos.

Bone scan positivity in non-metastatic, castrate-resistant prostate cancer: external validation study.

INTRODUCTION: Tables predicting the probability of a positive bone scan in men with non-metastatic, castrate-resistant prostate cancer have recently been reported. We performed an external validation study of these bone scan positivity tables. MATERIALS AND METHODS: We performed a retrospective cohort study of patients seen at a tertiary care medical center (1996-2012) to select patients with non-metastatic, castrate-resistant prostate cancer. Abstracted data included demographic, anthropometric, and disease-specific data such as patient race, BMI, PSA kinetics, and primary treatment. Primary outcome was metastasis on bone scan. Multivariable logistic regression was performed using generalized estimating equations to adjust for repeated measures. Risk table performance was assessed using ROC curves. RESULTS: We identified 6.509 patients with prostate cancer who had received hormonal therapy with a post-hormonal therapy PSA ≥2ng/mL, 363 of whom had non-metastatic, castrate-resistant prostate cancer. Of these, 187 patients (356 bone scans) had calculable PSA kinetics and ≥1 bone scan. Median follow-up after castrate-resistant prostate cancer diagnosis was 32 months (IQR: 19-48). There were 227 (64%) negative and 129 (36%) positive bone scans. On multivariable analysis, higher PSA at castrate-resistant prostate cancer (4.67 vs. 4.4ng/mL, OR=0.57, P=0.02), shorter time from castrate-resistant prostate cancer to scan (7.9 vs. 14.6 months, OR=0.97, P=0.006) and higher PSA at scan (OR=2.91, P<0.0001) were significantly predictive of bone scan positivity. The AUC of the previously published risk tables for predicting scan positivity was 0.72. CONCLUSION: Previously published risk tables predicted bone scan positivity in men with non-metastatic, castrate-resistant prostate cancer with reasonable accuracy.

[COVID-19 and psychological behavior: a systematic review of the psychological effects of 21st century pandemics]. / COVID-19 y comportamiento psicológico: revisión sistemática de los efectos psicológicos de las pandemias del siglo XXI.

The aim of this work was to conduct a systematic review on psychological behavior in the context of pandemic scenarios during the twenty-first century. We focused on empirical works and brief case reports of H1N1 flu and COVID-19. Our review included 32 papers published both in English or Spanish. We built a set of tables that allowed us to classify the information in four main categories, namely the psychological impact of the pandemic, whether people follow or not official measures to protect themselves against the pandemic, psychological adherence considerations implied as mediators to respect official strategies, and relevant methodological characteristics of the pandemic research. Results show that there are significant impacts on the psychological behavior of people, social groups and organizations in several dimensions, namely emotion, cognition, behavior, mental health, organization and psychosocial factors. In addition, we found that certain social groups experienced a critical psychosocial impact likely due to the pandemic. Psychosocial factors affecting adherence were also identified, which allow us to better understand how health strategies are followed by the population. Different psychosocial suggestions, which emerged from the papers reviewed, were systematized and should be considered as possible pandemic strategies to be implemented.

Predictores de identidad profesional en estudiantes de psicología: un estudio de análisis de senderos / Predictors of Professional Identity in Psychology Students: a Path Analysis Study

Resumen El objetivo de este estudio fue determinar la relación entre identidad profesional, identidad estudiantil universitaria, autoeficacia académica, autoeficacia profesional, créditos cursados y dificultad percibida ante la carrera, en estudiantes de psicología tradicionales y no tradicionales. Se utilizó un diseño transversal y un muestreo no probabilístico de 136 estudiantes de psicología de una universidad pública del norte chileno. Se aplicaron cuatro escalas y una encuesta sociodemográfica. Se realizó estadística descriptiva, análisis de correlación de Pearson, análisis de varianza (ANOVA) y análisis de senderos. Se encontraron diferencias significativas en la autoeficacia académica y profesional de estudiantes tradicionales y no tradicionales, y un modelo que predice la identidad profesional a partir de las variables identidad estudiantil universitaria, autoeficacia académica, autoeficacia profesional, créditos cursados y dificultad percibida ante la carrera (R 2 = .24). Los resultados se discuten en función de la literatura existente.

Abstract The aim of this study was to determine the relationship between professional identity, university student identity, academic self-efficacy, professional self-efficacy, credits taken and difficulty perceived in the career, in traditional and non-traditional psychology students. We used a cross-sectional design and a non-probabilistic sample of 136 psychology students from a public university in the north of Chile. Four scales and a sociodemographic survey were used. Descriptive statistics, Pearson correlation analysis, analysis of variance (ANOVA) and path analysis were performed. Results showed significant differences in the academic and professional self-efficacy grouped into traditional and non-traditional students and a model that predicts professional identity based on the variables of university student identity, academic self-efficacy, professional self-efficacy, credits taken and perceived difficulty in the career (R 2 = .24). Outcomes are discussed according to the existing literature.

Efficient Editing of the Nuclear APT Reporter Gene in Chlamydomonas reinhardtii via Expression of a CRISPR-Cas9 Module.

The clustered regularly interspaced short palindromic repeat/CRISPR-associated protein 9 (CRISPR/Cas9) technology is a versatile and useful tool to perform genome editing in different organisms ranging from bacteria and yeast to plants and mammalian cells. For a couple of years, it was believed that the system was inefficient and toxic in the alga Chlamydomonas reinhardtii. However, recently the system has been successfully implemented in this model organism, albeit relying mostly on the electroporation of ribonucleoproteins (RNPs) into cell wall deficient strains. This requires a constant source of RNPs and limits the application of the technology to strains that are not necessarily the most relevant from a biotechnological point of view. Here, we show that transient expression of the Streptococcus pyogenes Cas9 gene and sgRNAs, targeted to the single-copy nuclear apt9 gene, encoding an adenine phosphoribosyl transferase (APT), results in efficient disruption at the expected locus. Introduction of indels to the apt9 locus results in cell insensitivity to the otherwise toxic compound 2-fluoroadenine (2-FA). We have used agitation with glass beads and particle bombardment to introduce the plasmids carrying the coding sequences for Cas9 and the sgRNAs in a cell-walled strain of C. reinhardtii (CC-125). Using sgRNAs targeting exons 1 and 3 of apt9, we obtained disruption efficiencies of 3 and 30% on preselected 2-FA resistant colonies, respectively. Our results show that transient expression of Cas9 and a sgRNA can be used for editing of the nuclear genome inexpensively and at high efficiency. Targeting of the APT gene could potentially be used as a pre-selection marker for multiplexed editing or disruption of genes of interest.

Intercistronic expression elements (IEE) from the chloroplast of Chlamydomonas reinhardtii can be used for the expression of foreign genes in synthetic operons.

KEY MESSAGE: Two intercistronic regions were identified as functional intercistronic expression elements (IEE) for the simultaneous expression of aphA-6 and gfp in a synthetic operon in the chloroplast of C. reinhardtii. Chlamydomonas reinhardtii, a biflagellate photosynthetic microalga, has been widely used in basic and applied science. Already three decades ago, Chlamydomonas had its chloroplast genome transformed and to this day constitutes the only alga routinely used in transplastomic technology. Despite the fact that over a 100 foreign genes have been expressed from the chloroplast genome, little has been done to address the challenge of expressing multiple genes in the form of operons, a development that is needed and crucial to push forward metabolic engineering and synthetic biology in this organism. Here, we studied five intercistronic regions and investigated if they can be used as intercistronic expression elements (IEE) in synthetic operons to drive the expression of foreign genes in the chloroplast of C. reinhardtii. The intercistronic regions were those from the psbB-psbT, psbN-psbH, psaC-petL, petL-trnN and tscA-chlN chloroplast operons, and the foreign genes were the aminoglycoside 3'-phosphotransferase (aphA-6), which confers resistance to kanamycin, and the green fluorescent protein gene (gfp). While all the intercistronic regions yielded lines that were resistant to kanamycin, only two (obtained with intercistronic regions from psbN-psbH and tscA-chlN) were identified as functional IEEs, yielding lines in which the second cistron (gfp) was translated and generated GFP. The IEEs we have identified could be useful for the stacking of genes for metabolic engineering or synthetic biology circuits in the chloroplast of C. reinhardtii.

Sociodemographic differences among HIV-positive and HIV-negative recently pregnant women in Mexico City: A case-control study.

National HIV preventive programs in Mexico focus on high-risk groups that do not consider women, apart from prenatal screening. Nonetheless, the epidemic in women is growing, and there is a need to better understand sociodemographic factors in women living with HIV (WLH). We performed a case-control study in Mexico City, including HIV+ and HIV- women with a recent pregnancy to compare their sociodemographic characteristics and describe the circumstances of diagnosis in HIV+ women, as well as prenatal screening frequency in both groups. Fifty cases and 102 controls were interviewed. HIV+ women were more frequently the only economic support of the family (20% vs 0%, P < .0001). Thirty-eight percent of cases had their first pregnancy at ≤18 years, versus 16% of controls (odds ratio 2.47, 95% confidence interval 1.07-5.72, P = .03); 16% of cases had lived in the street; 6% reported transactional sex, versus none of the controls (P < .0001). In the multivariate analysis, there was strong evidence of an association between HIV infection and age at the time of the interview, history of sexually transmitted diseases, substance abuse, history of violence, and civil status. Only 6% of controls were tested for HIV during prenatal follow-up. WLH in this study faced important social vulnerability. Targeting women living in these social contexts might increase early diagnosis and could tailor HIV prevention strategies. Prenatal coverage needs to be improved and should represent a national priority.

mRNA imaging in the chloroplast of Chlamydomonas reinhardtii using the light-up aptamer Spinach.

Light-up aptamers are practical tools to image RNA localization in vivo. A now classical light-up aptamer system is the combination of the 3,5-difluoro-4-hydroxybenzylidene (DFHBI) fluorogen and the RNA aptamer Spinach, which has been successfully used in bacterial and mammalian cells. However, light-up aptamers have not been used in algae. Here, we show that a simple vector, carrying Spinach, transcriptionally fused to the aphA-6 gene, can be effectively used to generate a functional light-up aptamer in the chloroplast of Chlamydomonas reinhardtii. After incubation with DFHBI, lines expressing the aphA-6/Spinach mRNA were observed with laser confocal microscopy to evaluate the functionality of the light-up aptamer in the chloroplast of C. reinhardtii. Clear and strong fluorescence was localized to the chloroplast, in the form of discrete spots. There was no background fluorescence in the strain lacking Spinach. Light-up aptamers could be further engineered to image RNA or to develop genetically encoded biosensors in algae.

Cultural effects on mindreading.

People from other cultural backgrounds sometimes seem inscrutable. We identified a potential cause of this phenomenon in two experiments demonstrating that adults' mental state inferences are influenced by the cultural identity of the target. We adapted White, Hill, Happé, and Frith's (2009) Strange Stories to create matched intra-cultural and cross-cultural mindreading and control conditions. Experiment 1 showed that Australian participants were faster to respond and received higher scores in the intra-cultural mindreading condition relative to the cross-cultural mindreading condition, but performance in the control conditions was equivalent. Experiment 2 replicated this pattern in independent samples of Australian and Chilean participants. These findings have important implications for cross-cultural communication and understanding.

Production of Recombinant Proteins in the Chloroplast of the Green Alga Chlamydomonas reinhardtii.

Chloroplast transformation in the green algae Chlamydomonas reinhardtii can be used for the production of valuable recombinant proteins. Here, we describe chloroplast transformation of C. reinhardtii followed by protein detection. Genes of interest integrate stably by homologous recombination into the chloroplast genome following introduction by particle bombardment. Genes are inherited and expressed in lines recovered after selection in the presence of an antibiotic. Recombinant proteins can be detected by conventional techniques like immunoblotting and purified from liquid cultures.

Influencia de variables organizacionales en la calidad de vida laboral de funcionarios del sector público de salud en el extremo norte de Chile / Influence of Organizational Variables in Quality of Working Life of Officials Public Health Sector in the Far North of Chile

En el presente estudio se describe la calidad de vida laboral y su relación con el clima organizacional, la satisfacción laboral y el engagement en funcionarios de organizaciones públicas de salud de la ciudad de Arica, Chile. Participaron 142 sujetos de ambos sexos. Se utilizaron el Inventario de Calidad de Vida Laboral, el Inventario de Clima Organizacional, el Cuestionario de Satisfacción Laboral S21/26 y el Cuestionario de Engagement. Los resultados muestran una relación significativa entre la calidad de vida laboral y las variables organizacionales medidas, observando la presencia de diferencias significativas en función del estamento administrativo de los funcionarios. Conjuntamente, se encontró que la variable engagement modula la relación entre la calidad de vida laboral, clima organizacional y satisfacción laboral. Estos resultados evidencian la asociación entre las variables organizacionales e interpersonales que confluyen en el ámbito laboral con las valoraciones subjetivas que los sujetos construyen sobre las características de su entorno de trabajo, modulando su implicación y productividad.

We describe the Quality of Working Life and its relationship with the Organizational Climate, Job Satisfaction and Engagement in officials of public health organization in the city of Arica, Chile. 142 adult subjects of both sexes. We used the Inventory of Quality of Work Life, Organizational Climate Inventory, Job Satisfaction Questionnaire S21/26, and Engagement Questionnaire. The results show a significant relationship between the quality of working life and organizational variables measures, noting the presence of significant differences in the Quality of Working Life in terms of establishment of civil administration. Jointly, we found that the variable Engagement modulates the relation between Quality of Working Life, organizational climate and job satisfaction. These results demonstrate the association between organizational and interpersonal variables that come together in the workplace, with subjective assessments that subjects build on the characteristics of their work environment, modulating their involvement and productivity.

Hidrodinámica aplicada a la gestión y la conservación de ecosistemas marinos y costeros: Isla Gorgona, Océano Pacífico Colombiano / Hydrodynamics applied to the management and conservation of marine and coastal ecosystems: Gorgona Island, Colombian Pacific Ocean

Palmeras (Gorgona National Park) is one of the most important sites for sea turtle nesting in South and Central America. Because of the morphological processes affecting the beach, the turtle nests are increasingly exposed to the impact of waves and tides, threatening conservation. A study was made to determine the hydrodynamical processes of the zone adjacent to Playa Palmeras, which affects directly the morphodynamical behavior of the beach and thus the preservation of the nests. Field measurements and numerical modeling were used to obtain the general circulation patterns and thermohaline structure behavior in the area in order to determine the spatial and temporal variability of waves and its effects on the beach. A marked seasonality was found, both in the waves and the currents, influenced mainly by the meridional displacement of the ITCZ (Inter-Tropical Convergence Zone) and an interannual variability of the waves, associated with ENSO (El Niño Southern Oscillation). The flooding levels of the beach were determined and flooding probability maps were made, where safer sites to locate the turtle nests could be identified. These maps serve the officials responsible of monitoring the turtles as a tool to take decisions on moving the nests, since they have flood risk information for any point on the beach. The results show that the middle zone north of the beach is the one with the lowest risk of flooding, therefore the most appropriate zone to relocate nests that are in high risk areas. Rev. Biol. Trop. 62 (Suppl. 1): 133-147. Epub 2014 February 01.

Playa Palmeras (En el Parque Nacional Isla Gorgona) es uno de los sitios más importantes para la anidación de tortugas marinas en América del Sur y Centroamérica. Debido a procesos morfológicos que afectan la playa, los nidos de las tortugas se han visto cada vez más expuestos al impacto del oleaje y la marea, poniendo en riesgo la conservación de éstas especies. Se llevó a cabo un estudio para conocer los procesos hidrodinámicos de la zona costera en Playa Palmeras, de los cuales depende el comportamiento morfodinámico de la playa y la preservación de los nidos. Se usó modelación numérica y mediciones en campo para conocer la variabilidad espacio-temporal del oleaje y obtener los patrones generales de circulación y la estructura termohalina de la zona. Se encontró un marcado ciclo anual, tanto en el oleaje como en las corrientes, influenciado por la Zona de Convergencia Intertropical (ZCIT) y una variabilidad interanual del oleaje, asociada a El Niño Oscilación del Sur (ENSO). Se estimó la cota de inundación de la playa y se crearon mapas de probabilidad de inundación, identificando los sitios potencialmente más seguros para la anidación. Los resultados muestran que hacia el norte de la playa está la zona de menor riesgo.

Renal tuberculosis.

BACKGROUND: tuberculosis (TB) is a disease with a high incidence and prevalence worldwide. Renal TB is the second most common extrapulmonary form of TB. The purpose of this report is to present the case of a patient with renal TB in order to emphasize the importance of this disease. CLINICAL CASE: we report the case of a 30-year-old female who presented with fever, cough, diaphoresis and an abdominal right flank mass. Right hydronephrosis, dilated collector system and loss of renal function were documented. A right nephrectomy was performed. Histopathological exam revealed acid-fast mycobacteria, granulomas and multinucleated Langhans-type giant cells. Renal TB was diagnosed and anti-TB treatment was initiated. CONCLUSIONS: renal TB is a disease whose incidence has increased in relation to the TB epidemic. Renal TB should be considered in the evaluation of renal masses.