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Eur J Case Rep Intern Med ; 7(10): 001754, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-33083353

RESUMEN

Thyroid storm is a rare, life-threatening condition that can be caused by various pathologies including serious conditions associated with human chorionic gonadotropin (hCG)-producing tumours. We present the case of a 17-year-old male patient with a 1-month history of dyspnoea and a 3-day history of palpitations and fever. General examination revealed a left testicular mass. Blood tests revealed ß-hCG >225,000 mIU/ml, thyroid-stimulating hormone (TSH) 0.02 IU/ml, and thyroxine (T4) 19.07 µg/dl. He was admitted with thyroid storm. Treatment with antithyroid drugs and chemotherapy was started, but the patient died on the third day of admission. This case highlights a rare occurrence of thyroid storm linked to testicular choriocarcinoma, and provides a necessary reminder that, in some instances, hCG at very high levels can exert a thyrotropic effect due to its molecular structure, which is similar to that of TSH. LEARNING POINTS: Thyroid storm is rarely associated with testicular choriocarcinoma.Sometimes, human chorionic gonadotropin at very high levels can exert a thyrotropic effect due to its molecular structure, which is similar to that of thyroid-stimulating hormone.The clinical course and management of thyroid storm secondary to testicular choriocarcinoma in a young male is described.

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